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公开(公告)号:US20200281225A1
公开(公告)日:2020-09-10
申请号:US15773363
申请日:2016-11-04
发明人: Elijah G. Kiarie , Luis Fernando Romero Millan , Laura Payling , Maria Walsh , Susan Arent Lund
IPC分类号: A23K10/18 , A23K20/189 , A23K20/174 , A23K50/30
摘要: Disclosed is feed additive composition consisting essentially of a direct fed microbial comprising one or more bacterial strains in combination with at least one protease and a method for improving the performance of a subject or for improving digestibility of a raw material in a feed, which method comprising administering to a subject a direct fed microbial in combination with a protease.
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公开(公告)号:US10695384B2
公开(公告)日:2020-06-30
申请号:US16181427
申请日:2018-11-06
发明人: Luis Fernando Romero Millan , Gregory Ross Siragusa , Mari Ellen Davis , Alexandra Helena Smith
IPC分类号: A61K35/741 , C12N1/20 , A23K20/189 , C12R1/125 , A23K40/10 , A23K40/30 , A23K10/18 , A23K50/75 , A61K35/742 , A61K38/46 , A61K38/47 , A61K38/48
摘要: A feed additive composition comprising a direct fed microbial in combination with a protease, a xylanase, an amylase and a phytase, and a method for improving the performance of a subject or for improving digestibility of a raw material in a feed (e.g. nutrient digestibility, such as amino acid digestibility), or for improving nitrogen retention, or for avoiding the negative effects of necrotic enteritis or for improving feed conversion ratio (FCR) or for improving weight gain in a subject or for improving feed efficiency in a subject or for modulating (e.g. improving) the immune response of the subject or for promoting the growth of beneficial bacteria in the gastrointestinal tract of a subject, which method comprising administering to a subject a direct fed microbial in combination with a protease, a xylanase, an amylase and a phytase.
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公开(公告)号:US20150351433A1
公开(公告)日:2015-12-10
申请号:US14418906
申请日:2012-08-03
发明人: Susan Lund Arent , Brian Sogaard Laursen , Elijah Gituanjah Kiarie , Luis Fernando Romero Millan , Zhenghong Zhang , Rosalyn Lau , Zheyong Yu , Soren Dalsgaard
CPC分类号: C12C7/04 , A23K10/38 , A23K20/189 , A23L7/115 , A23L7/25 , A23L29/06 , A23L33/21 , A23V2002/00 , C12C5/004 , C12G2200/15 , C12N9/248 , C12Y302/01008 , Y02P60/873
摘要: The present invention provides a xylanase comprising amino acid sequence as set forth in SEQ ID No.1, SEQ ID No.2 or SEQ ID No.8, and a nucleotide sequence encoding said xylanase shown as SEQ ID No.3, SEQ ID No.4 or SEQ ID No.5. The present invention also provides a method of preparing a corn based product comprising contacting a plant composition comprising corn or a corn by-product or a combination thereof with said xylanase.
摘要翻译: 本发明提供包含如SEQ ID No.1,SEQ ID No.2或SEQ ID No.8所示的氨基酸序列的木聚糖酶和编码所述木聚糖酶的核苷酸序列,其显示为SEQ ID No.3,SEQ ID No .4或SEQ ID No.5。 本发明还提供了一种制备玉米基产品的方法,包括使包含玉米或玉米副产物或其组合的植物组合物与所述木聚糖酶接触。
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公开(公告)号:US20150150282A1
公开(公告)日:2015-06-04
申请号:US14418905
申请日:2013-08-02
发明人: Susan Lund Arent , Brian Sogaard Laursen , Elijah Gituanjah Kiarie , Luis Fernando Romero Millan , Zhenghong Zhang , Rosalyn Lau , Zheyong Yu , Mads Brogger Pedersen , Soren Dalsgaard
CPC分类号: A23L29/06 , A23K10/14 , A23K10/38 , A23K20/189 , A23L7/115 , A23L33/21 , C12C5/004 , C12N9/2482 , Y02P60/873
摘要: The present invention relates to a method of preparing a corn based product said method comprising contacting a plant composition comprising (consisting of or consisting essentially of) corn or a corn by-product or a combination thereof with a xylanase comprising: i) a polypeptide as set forth in SEQ ID No. 8 or SEQ ID No. 7 or SEQ ID No. 6; or ii) a variant, fragment, homologue, fragment or derivative thereof having at least 85% identity with SEQ ID No. 8 or SEQ ID No. 7 or SEQ ID No. 6; or with a xylanase encoded by: a) a nucleotide sequence shown herein as SEQ ID No. 3, SEQ ID No. 2 or SEQ ID No. 1; or b) a nucleotide sequence which can hybridize to the complement of SEQ ID No. 3, SEQ ID No. 2 or SEQ ID No. 1 under high stringency conditions: or c) a nucleotide sequence which has at least 80% identity with SEQ ID No. 3, SEQ ID No. 2 or SEQ ID No. 1. The present invention further relates to the use of the enzyme to produce corn based feedstuffs. The present invention yet further relates to a method of producing a fermented beverage comprising the step of contacting a mash and/or a wort with a xylanase comprising a polypeptide as set forth in SEQ ID No. 8 or SEQ ID No. 7 or SEQ ID No. 6; or a variant, fragment, homologue or derivative thereof having at least 85% identity with SEQ ID No. 8 or SEQ ID No. 7 or SEQ ID No. 6; or encoded by a nucleotide sequence shown herein as SEQ ID No. 3, SEQ ID No. 2 or SEQ ID No. 1, or a nucleotide sequence which can hybridize to the complement of SEQ ID No. 3, SEQ ID No. 2 or SEQ ID No. 1 under high stringency conditions, or a nucleotide sequence which has at least 80% identity with SEQ ID No. 3, SEQ ID No. 2 or SEQ ID No. 1.
摘要翻译: 本发明涉及一种制备玉米基产品的方法,所述方法包括将包含玉米或玉米副产物或其组合的玉米或其组合的(由或由其组成)的植物组合物与木聚糖酶接触,所述木聚糖酶包含:i) 如SEQ ID No.8或SEQ ID No.7或SEQ ID No.6所示; 或ii)与SEQ ID No.8或SEQ ID No.7或SEQ ID No.6具有至少85%同一性的变体,片段,同源物,片段或衍生物; 或与由以下编码的木聚糖酶组合:a)本文所示的SEQ ID No.3,SEQ ID No.2或SEQ ID No.1的核苷酸序列; 或b)在高度严格条件下可以与SEQ ID No.3,SEQ ID No.2或SEQ ID No.1的互补序列杂交的核苷酸序列:或c)与SEQ ID No至少具有80%同一性的核苷酸序列 ID No.3,SEQ ID No.2或SEQ ID No.1。本发明还涉及该酶用于生产玉米基饲料的用途。 本发明进一步涉及一种生产发酵饮料的方法,该方法包括使醪液和/或麦芽汁与包含如SEQ ID No.8或SEQ ID No.7或SEQ ID No.7所示的多肽的木聚糖酶接触的步骤 6号 或其与SEQ ID No.8或SEQ ID No.7或SEQ ID No.6具有至少85%同一性的变体,片段,同系物或衍生物; 或由本文所示的核苷酸序列编码,如SEQ ID No.3,SEQ ID No.2或SEQ ID No.1,或可与SEQ ID No.3,SEQ ID No.2的互补序列杂交的核苷酸序列或 在高严格条件下的SEQ ID No.1,或与SEQ ID No.3,SEQ ID No.2或SEQ ID No.1具有至少80%同一性的核苷酸序列。
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公开(公告)号:US11172693B2
公开(公告)日:2021-11-16
申请号:US16257556
申请日:2019-01-25
IPC分类号: A23K40/10 , C12N1/20 , C12N9/16 , A23K40/30 , A23K10/18 , A23K20/189 , A23K50/75 , A23K50/30 , A23K50/60 , C12R1/125
摘要: A feed additive composition comprising a direct fed microbial in combination with a protease, and a phytase, and a method for improving the performance of a subject or for improving digestibility of a raw material in a feed (e.g. nutrient digestibility, such as amino acid digestibility), or for improving nitrogen retention, or for improving the subject's resistance to necrotic enteritis or for improving feed conversion ratio (FCR) or for improving weight gain in a subject or for improving feed efficiency in a subject or for modulating (e.g. improving) the immune response of the subject or for promoting the growth of beneficial bacteria in the gastrointestinal tract of a subject, which method comprising administering to a subject a direct fed microbial in combination with a protease and a phytase.
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公开(公告)号:US20190223470A1
公开(公告)日:2019-07-25
申请号:US16257556
申请日:2019-01-25
IPC分类号: A23K40/10 , A23K50/60 , A23K50/30 , A23K50/75 , A23K20/189 , A23K10/18 , C12N1/20 , C12R1/125 , C12N9/50 , C12N9/16 , A23K40/30
摘要: A feed additive composition comprising a direct fed microbial in combination with a protease, and a phytase, and a method for improving the performance of a subject or for improving digestibility of a raw material in a feed (e.g. nutrient digestibility, such as amino acid digestibility), or for improving nitrogen retention, or for improving the subject's resistance to necrotic enteritis or for improving feed conversion ratio (FCR) or for improving weight gain in a subject or for improving feed efficiency in a subject or for modulating (e.g. improving) the immune response of the subject or for promoting the growth of beneficial bacteria in the gastrointestinal tract of a subject, which method comprising administering to a subject a direct fed microbial in combination with a protease and a phytase.
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公开(公告)号:US10058110B2
公开(公告)日:2018-08-28
申请号:US14618151
申请日:2015-02-10
发明人: Mari Ellen Davis , Justin Sawall , Anthony Neumann , Gregory Ross Siragusa , Luis Fernando Romero Millan
摘要: The disclosure relates to enzyme producing Bacillus strains that provide benefits to animals and methods of using these strains. In one embodiment, the disclosure relates compositions comprising the enzyme producing Bacillus strains. In yet another embodiment, the disclosure relates to a feed for an animal comprising enzyme producing Bacillus strains.
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公开(公告)号:US20190090525A1
公开(公告)日:2019-03-28
申请号:US16156572
申请日:2018-10-10
发明人: Susan Arent Lund , Brian Soegaard Laursen , Elijah G. Kiarie , Luis Fernando Romero Millan , Zhenghong Zhang , Rosalyn Lau , Zheyong Yu , Mads Broegger Pedersen , Soeren Dalsgaard
摘要: The present invention relates to a method of preparing a corn based product said method comprising contacting a plant composition comprising (consisting of or consisting essentially of) corn or a corn by-product or a combination thereof with a xylanase comprising: i) a polypeptide as set forth in SEQ ID No. 8 or SEQ ID No. 7 or SEQ ID No. 6; or ii) a variant, fragment homologue, fragment or derivative thereof having at least 85% identity with SEQ ID No. 8 or SEQ ID No. 7 or SEQ ID No. 6; or with a xylanase encoded by: a) a nucleotide sequence shown herein as SEQ ID No. 3. SEQ ID No. 2 or SEQ ID No. 1; or b) a nucleotide sequence which can hybridize to the complement of SEQ ID No. 3. SEQ ID No. 2 or SEQ ID No. 1 under high stringency conditions: or c) a nucleotide sequence which has at least 80% identity with SEQ ID No. 3. SEQ ID No. 2 or SEQ ID No. 1. The present invention further relates to the use of the enzyme to produce corn based feedstuffs. The present invention yet further relates to a method of producing a fermented beverage comprising the step of contacting a mash and/or a wort with a xylanase comprising a polypeptide as set forth in SEQ ID No. 8 or SEQ ID No. 7 or SEQ ID No. 6; or a variant, fragment, homologue or derivative thereof having at least 85% identity with SEQ ID No. 8 or SEQ ID No. 7 or SEQ ID No. 6; or encoded by a nucleotide sequence shown herein as SEQ ID No. 3, SEQ ID No. 2 or SEQ ID No. 1, or a nucleotide sequence which can hybridize to the complement of SEQ ID No. 3, SEQ ID No. 2 or SEQ ID No. 1 under high stringency conditions, or a nucleotide sequence which has at least 80% identity with SEQ ID No. 3, SEQ ID No. 2 or SEQ ID No. 1.
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公开(公告)号:US20180295858A1
公开(公告)日:2018-10-18
申请号:US15520140
申请日:2015-10-23
发明人: Svend Haaning , Karsten Matthias Kragh , Stepan Shipovskov , Andrei Miasnikov , Maria Ma , Luis Fernando Romero Millan , Luke Barnard , Shukun Yu , Ernst Meinjohanns , Steffen Bak , Päivi Nurminen , Heli Putaala
IPC分类号: A23K10/14 , C12N9/48 , A23K20/147 , A23K50/75 , A23K50/30
摘要: A method of preparing a feed additive composition comprising: (a) admixing at least one proline tolerant tripeptidyl peptidase predominantly having exopeptidase activity wherein said proline tolerant tripeptidyl peptidase is capable of cleaving tri-peptides from the N-terminus of peptides having (i) (A) Proline at P1; and (B) An amino acid selected from alanine, arginine, asparagine, aspartic acid, cysteine, glutamine, glutamic acid, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, serine, threonine, tryptophan, tyrosine, valine or synthetic amino acids at P1; or (ii) (a′) Proline at P1′; and (b′) An amino acid selected from alanine, arginine, asparagine, aspartic acid, cysteine, glutamine, glutamic acid, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, serine, threonine, tryptophan, tyrosine, valine or synthetic amino acids or amines at P1′; and one or more ingredients selected from the group consisting of a salt, polyol including sorbitol and glycerol, wheat or a wheat component, sodium acetate, sodium acetate trihydrate, potassium sorbate Talc, polyvinyl alcohol (PVA), benzoate, sorbiate, 1,3-propane diol, glucose, parabens, sodium chloride, citrate, metabisulfite, formate or a combination thereof; and (b) optionally packaging as well as uses of such proline tolerant tripeptidyl peptidases, feed additive compositions, feed additive kits, feeds or feedstuffs and/or premixes.
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公开(公告)号:US11931385B2
公开(公告)日:2024-03-19
申请号:US17368282
申请日:2021-07-06
发明人: Mai Faurschou Isaksen , Marion Bernardeau , Luis Fernando Romero Millan , Elijah G. Kiarie , Susan Lund Arent , Päivi Nurminen , Sofia Forssten , Daniel Petri , Elizabeth Ann Galbraith , Mari Ellen Davis
IPC分类号: A61K35/742 , A23K10/16 , A23K10/18 , A23K20/189 , A23K50/30 , A23K50/60 , A23K50/75 , A61K35/747 , A61K38/47
CPC分类号: A61K35/742 , A23K10/16 , A23K10/18 , A23K20/189 , A23K50/30 , A23K50/60 , A23K50/75 , A61K35/747 , A61K38/47 , A23V2400/11 , C12Y302/01008 , C12Y302/01021
摘要: A feed additive composition comprising a direct fed microbial (DFM), in combination with a xylanase (e.g. endo-1,4-β-d-xylanase) and a β-glucanase (and optionally a further fibre degrading enzyme).
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