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1.发明授权公开(公告)号：US09011874B2
公开(公告)日：2015-04-21
申请号：US13510601
申请日：2010-11-22
IPC分类号： A61K49/00 , A61K39/38 , A61K39/295 , A61K39/145 , A61K39/245 , C12Q1/70 , C12N15/863 , A61K39/12 , A61K39/00 , C07K14/005
CPC分类号： C12N15/86 , A61K39/00 , A61K39/12 , A61K39/145 , A61K2039/5256 , C07K14/005 , C07K2319/02 , C12N15/863 , C12N2710/24134 , C12N2710/24143 , C12N2760/16034 , C12N2760/16122 , C12N2760/16134
摘要： Embodiments of the present invention generally disclose methods, compositions and uses for generating and expressing poxvirus constructs. In some embodiments, constructs may contain an influenza virus gene segment. In certain embodiments, methods generally relate to making and using compositions of constructs including, but not limited to, poxvirus vaccine compositions. In other embodiments, vaccine compositions are reported of use in a subject.
摘要翻译： 本发明的实施方案通常公开了用于产生和表达痘病毒构建体的方法，组合物和用途。 在一些实施方案中，构建体可以含有流感病毒基因区段。 在某些实施方案中，方法通常涉及制备和使用构建体的组合物，包括但不限于痘病毒疫苗组合物。 在其它实施方案中，报告了在受试者中使用的疫苗组合物。
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公开(公告)号：US20130136767A1
公开(公告)日：2013-05-30
申请号：US13510601
申请日：2010-11-22
IPC分类号： C12N15/863 , A61K39/145 , A61K39/00
CPC分类号： C12N15/86 , A61K39/00 , A61K39/12 , A61K39/145 , A61K2039/5256 , C07K14/005 , C07K2319/02 , C12N15/863 , C12N2710/24134 , C12N2710/24143 , C12N2760/16034 , C12N2760/16122 , C12N2760/16134
摘要： Embodiments of the present invention generally disclose methods, compositions and uses for generating and expressing poxvirus constructs. In some embodiments, constructs may contain an influenza virus gene segment. In certain embodiments, methods generally relate to making and using compositions of constructs including, but not limited to, poxvirus vaccine compositions. In other embodiments, vaccine compositions are reported of use in a subject.
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3.发明授权Compositions, methods and uses for expression of enterobacterium-associated peptides 有权用于表达肠杆菌相关肽的组合物，方法和用途公开(公告)号：US09028809B2
公开(公告)日：2015-05-12
申请号：US13511652
申请日：2010-11-24
IPC分类号： A01N63/00 , A61K39/275 , A61K39/00 , A61K39/02
CPC分类号： A61K39/025 , A61K39/0291 , A61K2039/5256 , A61K2039/53 , C07K14/24 , C12N7/00 , C12N15/86 , C12N2710/24134 , C12N2710/24141 , C12N2710/24143 , C12N2710/24171 , C12N2840/002 , C12N2840/85 , Y02A50/407
摘要： Embodiments of the present invention generally disclose methods, compositions and uses for generating and expressing enterobacterial-associated peptides. In some embodiments, enterobacterial-associated peptides include, but are not limited to plague-associated peptides. In certain embodiments, methods generally relate to making and using compositions of constructs including, but not limited to, attenuated or modified vaccinia virus vectors expressing enterobacterial-associated peptides. In other embodiments, vaccine compositions are reported of use in a subject.
摘要翻译： 本发明的实施方案通常公开了用于产生和表达肠细菌相关肽的方法，组合物和用途。 在一些实施方案中，肠细菌相关肽包括但不限于瘟疫相关肽。 在某些实施方案中，方法通常涉及制备和使用构建体的组合物，包括但不限于表达肠细菌相关肽的减毒或修饰的痘苗病毒载体。 在其它实施方案中，报告了在受试者中使用的疫苗组合物。
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4.发明授权Compositions, methods and uses for poxvirus elements in vaccine constructs against influenza virus subtypes or strains 有权针对流感病毒亚型或株系的疫苗结构中痘病毒元件的组成，方法和用途公开(公告)号：US09005632B2
公开(公告)日：2015-04-14
申请号：US13555026
申请日：2012-07-20
IPC分类号： A61K49/00 , A61K39/38 , A61K39/295 , A61K39/145 , A61K39/245 , C12Q1/70 , C12N15/863 , A61K39/12 , C07K14/005 , A61K39/00
CPC分类号： A61K39/145 , A61K39/00 , A61K39/12 , A61K2039/5254 , A61K2039/5256 , A61K2039/545 , A61K2039/58 , A61K2039/70 , C07K14/005 , C07K2319/02 , C12N15/863 , C12N2710/24143 , C12N2760/16034 , C12N2760/16122 , C12N2760/16134
摘要： Embodiments of the present invention generally disclose methods, compositions and uses for generating and expressing poxvirus constructs. In some embodiments, constructs may contain an influenza virus gene segment. In certain embodiments, methods generally relate to making and using compositions of constructs including, but not limited to, poxvirus vaccine compositions having two or more influenza gene segments. In other embodiments, vaccine compositions are reported of use in a subject.
摘要翻译： 本发明的实施方案通常公开了用于产生和表达痘病毒构建体的方法，组合物和用途。 在一些实施方案中，构建体可以含有流感病毒基因区段。 在某些实施方案中，方法通常涉及制备和使用构建体的组合物，包括但不限于具有两个或更多个流感基因片段的痘病毒疫苗组合物。 在其它实施方案中，报告了在受试者中使用的疫苗组合物。
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公开(公告)号：US20130209513A1
公开(公告)日：2013-08-15
申请号：US13555026
申请日：2012-07-20
IPC分类号： C12N15/863
CPC分类号： A61K39/145 , A61K39/00 , A61K39/12 , A61K2039/5254 , A61K2039/5256 , A61K2039/545 , A61K2039/58 , A61K2039/70 , C07K14/005 , C07K2319/02 , C12N15/863 , C12N2710/24143 , C12N2760/16034 , C12N2760/16122 , C12N2760/16134
摘要： Embodiments of the present invention generally disclose methods, compositions and uses for generating and expressing poxvirus constructs. In some embodiments, constructs may contain an influenza virus gene segment. In certain embodiments, methods generally relate to making and using compositions of constructs including, but not limited to, poxvirus vaccine compositions having two or more influenza gene segments. In other embodiments, vaccine compositions are reported of use in a subject.
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公开(公告)号：US20130034583A1
公开(公告)日：2013-02-07
申请号：US13511652
申请日：2010-11-24
IPC分类号： C12N15/63 , A61P37/04 , A61K39/275
CPC分类号： A61K39/025 , A61K39/0291 , A61K2039/5256 , A61K2039/53 , C07K14/24 , C12N7/00 , C12N15/86 , C12N2710/24134 , C12N2710/24141 , C12N2710/24143 , C12N2710/24171 , C12N2840/002 , C12N2840/85 , Y02A50/407
摘要： Embodiments of the present invention generally disclose methods, compositions and uses for generating and expressing enterobacterial-associated peptides. In some embodiments, enterobacterial-associated peptides include, but are not limited to plague-associated peptides. In certain embodiments, methods generally relate to making and using compositions of constructs including, but not limited to, attenuated or modified vaccinia virus vectors expressing enterobacterial-associated peptides. In other embodiments, vaccine compositions are reported of use in a subject.
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