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    VARIABLE GEOMETRY BALLOON CATHETER AND METHOD
    1.
    发明申请
    VARIABLE GEOMETRY BALLOON CATHETER AND METHOD 审中-公开
    可变几何气球导管和方法

    公开(公告)号：US20100114269A1

    公开(公告)日：2010-05-06

    申请号：US12609463

    申请日：2009-10-30

    申请人： Dan WITTENBERGER ,  Marwan ABBOUD ,  Iona Alina DEAC

    发明人： Dan WITTENBERGER ,  Marwan ABBOUD ,  Iona Alina DEAC

    IPC分类号： A61F7/12 ,  A61M25/10

    CPC分类号： A61B18/02 ,  A61B2017/00256 ,  A61B2017/00867 ,  A61B2017/22051 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61M25/1002 ,  A61M29/02 ,  A61M2029/025

    摘要： A medical device is provided that may include a catheter body having proximal and distal portions, a fluid injection lumen disposed within elongate body, and a guidewire lumen disposed within the elongate body. A tip portion defining a cavity in fluid communication with the fluid injection lumen may be coupled to the distal end of the guidewire lumen, and an expandable element may be coupled to the distal portion of the catheter body and to the tip portion, such that the expandable element is in fluid communication with the fluid injection lumen. A shaping element may at least partially surround the expandable element, where the shaping element is configurable in a first geometric configuration and a second geometric configuration.

    摘要翻译： 提供了一种医疗装置，其可以包括具有近端部分和远端部分的导管主体，设置在细长主体内的流体注射腔，以及设置在细长主体内的导丝管腔。 限定与流体注射腔流体连通的空腔的尖端部分可以联接到导丝管腔的远端，并且可扩张元件可以联接到导管主体的远端部分和尖端部分，使得 可膨胀元件与流体注射内腔流体连通。 成形元件可以至少部分地围绕可膨胀元件，其中成形元件可配置为第一几何配置和第二几何配置。

    MESH LEAK DETECTION SYSTEM FOR A MEDICAL DEVICE
    3.
    发明申请
    MESH LEAK DETECTION SYSTEM FOR A MEDICAL DEVICE 有权
    用于医疗设备的MESH泄漏检测系统

    公开(公告)号：US20100204687A1

    公开(公告)日：2010-08-12

    申请号：US12767012

    申请日：2010-04-26

    申请人： Marwan ABBOUD ,  Dan WITTENBERGER

    发明人： Marwan ABBOUD ,  Dan WITTENBERGER

    IPC分类号： A61B18/02 ,  A61M25/10

    CPC分类号： G01M3/02 ,  A61B18/02 ,  A61B2017/00119 ,  A61B2017/22051 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61M25/0147 ,  A61M25/10 ,  A61M2205/15

    摘要： The present invention provides a surgical device including an elongate body defining a fluid flow path therethrough. An expandable element may be coupled to the elongate body and placed in fluid communication with the fluid flow path. Moreover, the surgical device may include a first leak detection element at least partially surrounding a portion of the expandable element, and a second leak detection element may be provided in fluid communication with the fluid flow path. In addition, a console may be provided, where the console may be in communication with the first and second leak detection elements. Further, a supply of cryogenic fluid as well as a vacuum source may be provided in fluid communication with the fluid flow path.

    摘要翻译： 本发明提供一种手术装置，其包括限定通过其中的流体流动通道的细长主体。 可膨胀元件可以联接到细长主体并且被放置成与流体流动路径流体连通。 此外，手术装置可以包括至少部分地围绕可膨胀元件的一部分的第一泄漏检测元件，并且第二泄漏检测元件可以设置成与流体流动路径流体连通。 此外，可以提供控制台，其中控制台可以与第一和第二泄漏检测元件通信。 此外，可以提供与流体流动路径流体连通的低温流体以及真空源的供应。

    THERMOCOUPLE-CONTROLLED CATETHER COOLING SYSTEM
    5.
    发明申请
    THERMOCOUPLE-CONTROLLED CATETHER COOLING SYSTEM 有权
    热电偶控制CATETHER冷却系统

    公开(公告)号：US20090287201A1

    公开(公告)日：2009-11-19

    申请号：US12122436

    申请日：2008-05-16

    申请人： Jean-Pierre LALONDE ,  Dan WITTENBERGER ,  Marwan ABBOUD ,  Constantin Bogdan CIOBOTARU ,  Ramin SABBAGHE-KERMANI

    发明人： Jean-Pierre LALONDE ,  Dan WITTENBERGER ,  Marwan ABBOUD ,  Constantin Bogdan CIOBOTARU ,  Ramin SABBAGHE-KERMANI

    IPC分类号： A61B18/02 ,  A61F7/12 ,  A61M25/01

    CPC分类号： A61B18/02 ,  A61B2018/00023 ,  A61B2018/0022 ,  A61B2018/00797 ,  A61B2018/00821 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61M25/0136

    摘要： The present invention provides a medical system, including a catheter defining an injection lumen, a chamber in fluid communication with the injection lumen, and an exhaust lumen in fluid communication with the chamber; a first temperature sensor positioned in the exhaust lumen proximal to the chamber; a second temperature sensor positioned in the chamber; and a console in electrical communication with the first and second temperature sensors, the controller modifying coolant flow through the medical device based at least in part upon a signal received from the first and second temperature sensor. The system may further include a thermally-conductive element circumscribing a substantial portion of the exhaust lumen proximal to the chamber, where the first temperature sensor is mounted to the thermally-conductive element, and the thermally-conductive element may include at least one of a braid, coil, and band.

    摘要翻译： 本发明提供了一种医疗系统，其包括限定注射腔的导管，与注射腔流体连通的腔室和与腔室流体连通的排气腔; 定位在靠近所述腔室的所述排气腔内的第一温度传感器; 位于所述室中的第二温度传感器; 以及与所述第一和第二温度传感器电连通的控制台，所述控制器至少部分地基于从所述第一和第二温度传感器接收的信号来改变通过所述医疗设备的冷却剂流动。 该系统还可以包括限定靠近腔室的排气腔的主要部分的导热元件，其中第一温度传感器安装到导热元件，并且导热元件可以包括以下中的至少一个： 辫子，线圈和乐队。

    METHOD AND APPARATUS FOR INFLATING AND DEFLATING BALLOON CATHETERS
    7.
    发明申请
    METHOD AND APPARATUS FOR INFLATING AND DEFLATING BALLOON CATHETERS 有权
    用于泄露和排除气泡导管的方法和装置

    公开(公告)号：US20090088735A1

    公开(公告)日：2009-04-02

    申请号：US12238865

    申请日：2008-09-26

    申请人： Marwan ABBOUD ,  Rachid MAHROUCHE

    发明人： Marwan ABBOUD ,  Rachid MAHROUCHE

    IPC分类号： A61B18/02

    CPC分类号： A61M25/10187 ,  A61B18/02 ,  A61B18/1492 ,  A61B2017/22051 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61M25/1011 ,  A61M25/10182 ,  A61M25/10185 ,  A61M2025/1013 ,  A61M2205/15 ,  A61M2205/3337

    摘要： A system and method for controlling the inflation, ablation, and deflation of a balloon catheter. The system includes a balloon catheter, a console, a pressurized gas or liquid inflation source, and an umbilical system to deliver pressurized coolant to the balloon catheter. The system may include controller that monitors the amount of pressure and volume within the balloon catheter. During inflation, the pressure and/or volume of fluid within the balloon is maintained at a target amount in order to provide sufficient mechanized pressure against the desired target region. The system limits the inflation pressure such that a safe quantity of gas would be released should a leak occur. If the amount falls below a certain threshold level, gas or fluid egress is presumed and the inflation process is halted.

    摘要翻译： 用于控制气囊导管的充气，消融和放气的系统和方法。 该系统包括球囊导管，控制台，加压气体或液体充气源，以及将加压冷却剂输送到球囊导管的脐带系统。 该系统可以包括监控气囊导管内的压力和体积的量的控制器。 在充气期间，气囊内的流体的压力和/或体积保持在目标量，以便提供相对于期望目标区域的足够的机械化压力。 该系统会限制通气压力，以便在发生泄漏时释放出安全数量的气体。 如果该量低于某一阈值水平，则假设气体或流体出口，并且暂停充气过程。

    CLOSED LOOP CATHETER COOLANT SYSTEM
    8.
    发明申请
    CLOSED LOOP CATHETER COOLANT SYSTEM 有权
    封闭式导管冷却系统

    公开(公告)号：US20080077124A1

    公开(公告)日：2008-03-27

    申请号：US11948321

    申请日：2007-11-30

    申请人： Jean-Pierre LALONDE ,  Marwan ABBOUD

    发明人： Jean-Pierre LALONDE ,  Marwan ABBOUD

    IPC分类号： A61B18/02

    CPC分类号： A61B18/02 ,  A61B2017/00092 ,  A61B2017/00119 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61F7/12

    摘要： A coolant system for a cryoablation or treatment probe such as a mapping or ablation catheter, or a treatment wand, includes a compressor and condenser having a low pressure inlet side and a high pressure outlet side, wherein the outlet side passes through a heat exchanger and is cooled by the inlet side and conditioned for injection to a catheter inlet. A vacuum return system connectable to the catheter outlet draws thermally expended coolant from the catheter and returns it to the low pressure inlet side. A motorized pressure regulator between the heat exchanger and the catheter inlet determines the pressure of coolant passing into the catheter and thus regulates the cooling rate for a selected mapping or ablation regimen. The low pressure compressor inlet supply preferentially conditions the pressurized coolant to ambient temperature or lower before injection into the catheter, allowing the coolant to travel through the body at ambient before expansion in the tip. In a preferred embodiment, a coolant reservoir feeds into the low pressure inlet side and receives a return flow of excess fluid from a branch off the outlet side of the compressor. The vacuum return assures that coolant does not leak into the blood stream, and preferably various check valves and bypass valves operate in the event of pressure buildup to return fluid to either the inlet or supply from different points along the loop. The coolant mixture preferably has a boiling point of approximately −60° Fahrenheit at about 1-2 bar, and may be compressed to several hundred psi. The entire system is amenable to microprocessor control for providing ablation cooling cycles to operate the catheter tip in accordance with a selected protocol, and for effecting system functions such as recharging and venting of the supply, and shutting down during nonuse or upon occurrence of a fault condition.

    摘要翻译： 用于冷冻消融或治疗探针如冷凝或消融导管或治疗棒的冷却剂系统包括具有低压入口侧和高压出口侧的压缩机和冷凝器，其中出口侧通过热交换器和 通过入口侧冷却并调节注射到导管入口。 可连接到导管出口的真空返回系统从导管吸出热消耗的冷却剂并将其返回到低压入口侧。 热交换器和导管入口之间的电动压力调节器确定冷却剂通过导管的压力，从而调节所选择的定位或消融方案的冷却速率。 低压压缩机入口供应优选地将加压的冷却剂调节到环境温度或更低温度，然后注入导管，允许冷却剂在环境温度下在尖端中膨胀之前穿过身体。 在优选实施例中，冷却剂储存器进入低压入口侧并接收来自压缩机出口侧的分支的多余流体的回流。 真空回流确保冷却剂不会泄漏到血液中，并且优选地，在压力累积的情况下，各种止回阀和旁通阀操作，以将流体从沿着回路的不同点返回到入口或供应源。 冷却剂混合物优选在约1-2巴下具有约-60华氏度的沸点，并且可以压缩至几百磅/平方英寸。 整个系统适于微处理器控制，以根据所选择的方案提供消融冷却循环来操作导管尖端，并且用于实现系统功能，例如电源的再充电和排气，以及在不使用或发生故障时关闭。 条件。

    WIDE AREA ABLATION OF MYOCARDIAL TISSUE
    10.
    发明申请
    WIDE AREA ABLATION OF MYOCARDIAL TISSUE 有权

    公开(公告)号：US20080103493A1

    公开(公告)日：2008-05-01

    申请号：US11969321

    申请日：2008-01-04

    申请人： Marwan ABBOUD ,  Fredric MILDER ,  George KLEIN

    发明人： Marwan ABBOUD ,  Fredric MILDER ,  George KLEIN

    IPC分类号： A61B18/02

    CPC分类号： A61B18/02 ,  A61B2017/22051 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2018/0262

    摘要： The present invention advantageously provides a method and system for cryogenically ablating large areas of tissue within the left atrium. In an exemplary embodiment a cryotherapy device includes a catheter body having a substantially fixed diameter, a proximal end and a distal end; a first lumen for permitting passage of a cooling fluid from the proximal end to the distal end; a second lumen permitting return of the cooling fluid from the distal end to the proximal end; and an ablation element expandable from a first diameter that is substantially the same as the diameter of the catheter body to a second diameter that is at least twice the diameter of the catheter body, the ablation element having a surface portion that conforms to the uneven surface topography of the cardiac tissue. The ablation element can include one or more balloon and/or a flexible element that is deformed by moving the distal end of the catheter toward the proximal end of the catheter. The surface of the balloon can further be shaped by regulation of pressure within the one or more balloons. In an exemplary method a tissue ablation device is provided and tissue in the antrum of the left atrium is ablated with the device. In an exemplary method, only tissue in the antrum is ablated, and the ablation is created by freezing tissue.