Cosmetic composition containing an aqueous polymer dispersion and an insoluble silicone, and process and use thereof
    3.
    发明授权
    Cosmetic composition containing an aqueous polymer dispersion and an insoluble silicone, and process and use thereof 失效
    含有聚合物水分散体和不溶性硅氧烷的化妆品组合物及其工艺和用途

    公开(公告)号:US06703028B1

    公开(公告)日:2004-03-09

    申请号:US09689818

    申请日:2000-10-13

    IPC分类号: A61K700

    摘要: An aqueous or aqueous/alcoholic cosmetic composition which can be sprayed, comprising an aqueous dispersion of insoluble film-forming polymer particles and at least one insoluble silicone, wherein the polymer particles are present in a concentration greater than 15%, relative to the total weight of the composition, and further wherein the glass transition temperature of the insoluble polymer particles ranges from 15 to 35° C. The invention also relates to a process for the cosmetic treatment of keratinous substances using these compositions and to the use of the silicone for improving the quality of the spraying of the composition.

    摘要翻译: 可喷雾的水性或水性/醇类化妆品组合物,其包含不溶性成膜聚合物颗粒和至少一种不溶性硅氧烷的水性分散体,其中聚合物颗粒以相对于总重量的大于15%的浓度存在 的组合物,并且其中不溶性聚合物颗粒的玻璃化转变温度为15-35℃。本发明还涉及使用这些组合物和使用硅氧烷来改善角质化物质的美容处理方法 喷涂组合物的质量。

    Cosmetic composition comprising an aqueous non-ionic polymer dispersion
and process of using
    6.
    发明授权
    Cosmetic composition comprising an aqueous non-ionic polymer dispersion and process of using 失效
    包含非离子型聚合物水分散体的化妆品组合物和使用方法

    公开(公告)号:US6083494A

    公开(公告)日:2000-07-04

    申请号:US693640

    申请日:1996-08-09

    CPC分类号: A61Q5/06 A61K8/8152

    摘要: An aqueous or aqueous/alcoholic cosmetic composition comprising an aqueous dispersion of insoluble particles of a non-ionic film-forming polymer, the polymer particles being at a concentration greater than 15% by weight with respect to the total weight of the composition and the glass transition temperature of the polymer particles of the composition ranging from 15 to 35.degree. C. and a process for the cosmetic treatment of keratinous substances using these compositions.

    摘要翻译: 一种水性或水性/醇类化妆品组合物,其包含非离子成膜聚合物的不溶性颗粒的水性分散体,所述聚合物颗粒的浓度相对于组合物的总重量和玻璃的总重量大于15重量% 组合物的聚合物颗粒的转变温度为15至35℃,以及使用这些组合物来美化处理角质物质的方法。

    Flight Accident Insurance
    8.
    发明申请
    Flight Accident Insurance 失效
    飞行事故保险

    公开(公告)号:US20120245964A1

    公开(公告)日:2012-09-27

    申请号:US13488484

    申请日:2012-06-05

    IPC分类号: G06Q40/08

    CPC分类号: G06Q40/08

    摘要: A system for providing flight accident insurance at low price and fixed coverage comprises means for limiting the number of policies that can be sold on any given flight to not more than a predetermined number. The predetermined number may be 20. The system comprises an input device for receiving information from a traveler and an output device for providing an insurance quote to said traveler.

    摘要翻译: 以低价和固定覆盖面提供飞行事故保险的系统包括将任何给定航班上可以出售的政策数量限制在不超过预定数量的手段。 预定数量可以是20.系统包括用于从旅行者接收信息的输入装置和用于向所述旅行者提供保险报价的输出装置。

    Regulation of Autophagy and Cell Survival
    9.
    发明申请
    Regulation of Autophagy and Cell Survival 审中-公开
    自噬和细胞存活的调控

    公开(公告)号:US20080269259A1

    公开(公告)日:2008-10-30

    申请号:US11814365

    申请日:2006-01-19

    摘要: Methods of treating an individual who has been identified as having glycolysis dependent cancer are disclosed. The methods comprise the step of: administering to such an individual a combination of an anti-cancer composition that renders the cancer incapable of glycolysis and an autophagy inhibitor. Pharmaceutical compositions and kits comprising that renders the cancer incapable of glycolysis and an autophagy inhibit are also disclosed. Methods of treating an individual who has a disease characterized b cell degeneration and cell death due to autophagy are disclosed. The methods comprise administering to the individual a permeable form of a metabolic substrate that can be oxidized in the tricarboxylic acid cycle to produce NADH. Methods for identifying an autophagy inhibitor comprising performing a test assay using an apopto sis-resistant cell are disclosed.

    摘要翻译: 公开了已经鉴定为具有糖酵解依赖性癌症的个体的治疗方法。 所述方法包括以下步骤:向这样的个体施用使癌症不能糖酵解的抗癌组合物与自噬抑制剂的组合。 还公开了包含其的药物组合物和试剂盒,使癌症不能进行糖酵解和自噬抑制。 公开了治疗患有由于自噬引起的b细胞变性和细胞死亡的疾病的个体的方法。 所述方法包括向个体施用可在三羧酸循环中被氧化以产生NADH的代谢底物的可渗透形式。 公开了用于鉴定自噬抑制剂的方法,包括使用抗凋亡细胞进行测试测定。

    Compositions and methods for treating cancer
    10.
    发明申请
    Compositions and methods for treating cancer 有权
    用于治疗癌症的组合物和方法

    公开(公告)号:US20070259956A1

    公开(公告)日:2007-11-08

    申请号:US10556220

    申请日:2004-05-07

    IPC分类号: A61K31/215 A61K31/21

    CPC分类号: A61K31/34 A61K51/0491

    摘要: Methods of treating individuals identified as having cancer using ATP citrate lyase inhibitor and/or tricarboxylate transporter inhibitor are disclosed. Methods of inducing apoptosis in cancer cells using an ATP citrate lyase inhibitor and/or tricarboxylate transporter inhibitor are disclosed. Methods of treating an individual who has cancer comprising the steps of identifying the cancer as having a high rate of aerobic glycolysis, and administering an ATP citrate lyase inhibitor and/or tricarboxylate transporter inhibitor are disclosed. Methods of treating individuals who have cancer using compounds that inhibit the expression of ATP citrate lyase or tricarboxylate transporter are disclosed. Methods of identifying a compound with anticancer activity are disclosed.

    摘要翻译: 公开了使用ATP柠檬酸裂解酶抑制剂和/或三羧酸转运蛋白抑制剂治疗被鉴定为具有癌症的个体的方法。 公开了使用ATP柠檬酸裂解酶抑制剂和/或三羧酸转运蛋白抑制剂诱导癌细胞凋亡的方法。 公开了治疗患有癌症的个体的方法,包括将癌症鉴定为具有高比例的有氧糖酵解的步骤,以及施用ATP柠檬酸裂解酶抑制剂和/或三羧酸转运蛋白抑制剂。 公开了使用抑制ATP柠檬酸裂合酶或三羧酸转运蛋白的表达的化合物治疗患有癌症的个体的方法。 公开了鉴定具有抗癌活性的化合物的方法。