利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

42 条记录 (耗时 0.038 秒)

    Ceramic encapsulation with controlled layering by use of functionalized silanes
    1.
    发明授权
    Ceramic encapsulation with controlled layering by use of functionalized silanes 有权
    通过使用官能化硅烷控制分层的陶瓷封装

    公开(公告)号：US09192548B2

    公开(公告)日：2015-11-24

    申请号：US13168715

    申请日：2011-06-24

    申请人： Daniel H. Traynor ,  Hao Xu ,  Henry G. Traynor ,  Daniel H. Traynor ,  John Carson ,  Martin S. Flacks ,  Rachel Sullivan

    发明人： Daniel H. Traynor ,  Hao Xu ,  Henry G. Traynor ,  John Carson ,  Martin S. Flacks ,  Rachel Sullivan

    IPC分类号： B01J13/22 ,  A61K8/11 ,  A61K8/58 ,  A61Q19/00 ,  A61K8/02

    CPC分类号： A61K8/11 ,  A61K8/0279 ,  A61K8/585 ,  A61Q19/00

    摘要： This invention relates to a method for forming hollow silica-based particles suitable for containing one or more active ingredients or for containing other smaller particles which may include one or more active ingredients. The method comprises preparing an emulsion including a continuous phase that is polar or non-polar and a dispersed phase comprising droplets including (i) a polar active ingredient when the continuous phase is non-polar or (ii) a non-polar active ingredient when the continuous phase is polar; and adding a silica precursor to the emulsion such that the silica precursor can be emulsion templated on the droplets to form hollow silica-based particles. The silica precursor has the general formula (I): R1x—Si—(OR2)y, wherein R1 is selected from substituted and unsubstituted alkyl, substituted and unsubstituted aryl, alcohols, amines, amides, aldehydes, acids, esters, and functional groups having an unsaturated carbon-carbon bond, R2 is an alkyl group, x+y=4, and y=1, 2 or 3. The —OR2 group is a hydrolyzable organic group that exhibits an ability to form a silicon-oxygen bond chain as a result of hydrolysis and condensation.

    摘要翻译： 本发明涉及一种形成中空二氧化硅基颗粒的方法，该方法适于含有一种或多种活性成分或含有其它可包含一种或多种活性成分的较小颗粒。 该方法包括制备包含极性或非极性的连续相的乳液和包含液滴的分散相，包括（i）连续相为非极性时的极性活性成分或（ii）非极性活性成分， 连续相为极性; 并将二氧化硅前体添加到乳液中，使得二氧化硅前体可以在液滴上乳液模板化以形成中空二氧化硅基颗粒。 二氧化硅前体具有通式（I）：R1x-Si-（OR2）y，其中R1选自取代和未取代的烷基，取代和未取代的芳基，醇，胺，酰胺，醛，酸，酯和官能团 具有不饱和碳 - 碳键，R2是烷基，x + y = 4，y = 1,2或3. -OR2基团是表现出形成硅 - 氧键键的能力的可水解的有机基团 作为水解和缩合的结果。

    Ceramic Encapsulation With Controlled Layering By Use of Functionalized Silanes
    4.
    发明申请
    Ceramic Encapsulation With Controlled Layering By Use of Functionalized Silanes 有权
    通过使用功能化硅烷控制分层的陶瓷封装

    公开(公告)号：US20120107499A1

    公开(公告)日：2012-05-03

    申请号：US13168715

    申请日：2011-06-24

    申请人： Daniel H. Traynor ,  Hao Xu ,  Henry G. Traynor ,  Daniel H. Traynor ,  John Carson ,  Martin S. Flacks ,  Rachel Sullivan

    发明人： Daniel H. Traynor ,  Hao Xu ,  Henry G. Traynor ,  Daniel H. Traynor ,  John Carson ,  Martin S. Flacks ,  Rachel Sullivan

    IPC分类号： B29B9/12

    CPC分类号： A61K8/11 ,  A61K8/0279 ,  A61K8/585 ,  A61Q19/00

    摘要： This invention relates to a method for forming hollow silica-based particles suitable for containing one or more active ingredients or for containing other smaller particles which may include one or more active ingredients. The method comprises preparing an emulsion including a continuous phase that is polar or non-polar and a dispersed phase comprising droplets including (i) a polar active ingredient when the continuous phase is non-polar or (ii) a non-polar active ingredient when the continuous phase is polar; and adding a silica precursor to the emulsion such that the silica precursor can be emulsion templated on the droplets to form hollow silica-based particles. The silica precursor has the general formula (I): R1x—Si—(OR2)y, wherein R1 is selected from substituted and unsubstituted alkyl, substituted and unsubstituted aryl, alcohols, amines, amides, aldehydes, acids, esters, and functional groups having an unsaturated carbon-carbon bond, R2 is an alkyl group, x+y=4, and y=1, 2 or 3. The —OR2 group is a hydrolyzable organic group that exhibits an ability to form a silicon-oxygen bond chain as a result of hydrolysis and condensation.

    摘要翻译： 本发明涉及一种形成中空二氧化硅基颗粒的方法，该方法适于含有一种或多种活性成分或含有其它可包含一种或多种活性成分的较小颗粒。 该方法包括制备包含极性或非极性的连续相的乳液和包含液滴的分散相，包括（i）连续相为非极性时的极性活性成分或（ii）非极性活性成分， 连续相为极性; 并将二氧化硅前体添加到乳液中，使得二氧化硅前体可以在液滴上乳液模板化以形成中空二氧化硅基颗粒。 二氧化硅前体具有通式（I）：R1x-Si-（OR2）y，其中R1选自取代和未取代的烷基，取代和未取代的芳基，醇，胺，酰胺，醛，酸，酯和官能团 具有不饱和碳 - 碳键，R2是烷基，x + y = 4，y = 1,2或3. -OR2基团是表现出形成硅 - 氧键键的能力的可水解的有机基团 作为水解和缩合的结果。

    CARBOXAMIDO OPIOID COMPOUNDS
    8.
    发明申请
    CARBOXAMIDO OPIOID COMPOUNDS 审中-公开
    CARBOXAMIDO OPIOID化合物

    公开(公告)号：US20070244194A1

    公开(公告)日：2007-10-18

    申请号：US11766892

    申请日：2007-06-22

    申请人： John Carson ,  Philip Pitis

    发明人： John Carson ,  Philip Pitis

    IPC分类号： A61K31/195 ,  A61P25/00

    CPC分类号： A41D27/201 ,  A45F5/022 ,  A61K31/195 ,  Y10T24/1376

    摘要： This invention is directed to carboxamido opioid compounds pharmaceutically useful as agents for treating or modulating a central nervous system disorder and methods for treating or modulating a central nervous system disorder.

    摘要翻译： 本发明涉及药物上可用作治疗或调节中枢神经系统障碍的药物的甲酰胺阿片样物质和治疗或调节中枢神经系统疾病的方法。