摘要:
Disclosed are immunogenic Nogo receptor-1 polypeptides, Nogo receptor-1 antibodies, antigen-binding fragments thereof, soluble Nogo receptors and fusion proteins thereof and nucleic acids encoding the same. Also disclosed are compositions comprising, and methods for making and using, such Nogo receptor antibodies, antigen-binding fragments thereof, soluble Nogo receptors and fusion proteins thereof and nucleic acids encoding the same.
摘要:
The invention provides Sp35 polypeptides and fusion proteins thereof, Sp35 antibodies and antigen-binding fragments thereof and nucleic acids encoding the same. The invention also provides compositions comprising, and methods for making and using, such Sp35 antibodies, antigen-binding fragments thereof, Sp35 polypeptides and fusion proteins thereof.
摘要:
The invention provides methods for treating diseases involving aberrant amyloid-β (Aβ) peptide deposition, including Alzheimer's Disease, by the administration of Nogo receptor antagonists. The invention also provides method for reducing levels of Aβ peptide in a mammal by the administration of soluble Nogo receptor polypeptides
摘要:
Method and device for capturing images of a target object using image templates at a device are disclosed. The method includes rendering an image template on the display for determining a position of the target object in an image to be captured using the device; capturing a first image of the target object using the image sensor and displaying the captured first image on the display while keeping the image template on the display; extracting one or more features associated with the position of the target object from the captured first image; determining whether the one or more features extracted from the captured first image match the image template; and generating an alert signal in accordance with a determination that at least one of the one or more features extracted from the captured first image matches the image template.
摘要:
A socket and ratchet wrench comprises: an annular-toothed block rotatably received in a wrench body, and a socket. The annular-toothed block has a through engaging hole defined with multiple ribs each connected by a negative arc surface, the respective ribs includes two flat first engaging surfaces and one cambered second engaging surface connected the first engaging surfaces by an arc surface. At a first end of the socket are formed multiple grooves for mating with the respective ribs of the annular-toothed block, and at the second end are provided multiple planes for engaging with the second engaging surfaces of the respective ribs.
摘要:
A demultiplexer disposed between a touch sensor circuit and electrodes of a touchpad electrode grid, wherein instead of using the touch sensor circuitry to directly drive each electrode, the touch sensor circuitry instead transmits control signals to the demultiplexer, wherein the control signals instruct the demultiplexer to select a subset of the plurality of electrodes to be driven, and thereby perform object detection and tracking, wherein by using the demultiplexer to drive electrodes, a much greater number of electrodes can be driven by the touch sensor circuit, thereby increasing the effective size of a touchpad that can be controlled by the touch sensor circuitry.
摘要:
Therapy patches provide portable massaging devices that can also deliver topical treatment chemicals. These patches can be adhered to the skin via an adhesive layer that is also impregnated with the treatment chemical. Kits are also provided to create a string of linked patches that can be used together or separately, and a microcontroller controls the vibration of the device for optimized massaging effects.
摘要:
An optical display that can also function as an optical touchpad, wherein a substrate is used as a light guide to provide a plurality of paths for light to travel and arrive at a display region, wherein a unique image is selectively made visible in the display region by choosing to transmit light to the display region through one of the plurality of paths, and wherein optical sensors are also associated with the display region to thereby enable detection of an object that is in contact with at least one display region.
摘要:
A graphical documentation system allows clinicians to record information about specific zones of an anatomical image in a fast, intuitive, and easy to understand manner. A graphical user interface system supporting recording of patient medical and other data, includes a display processor for initiating display of data representing a display image. The display image includes, a first area presenting a graphical anatomical image retrieved from a repository, the graphical anatomical image identifies at least one anatomical zone and a second area presents a form associated with a zone selected via user interaction with the identified graphical anatomical image zone. A repository associates a particular form of a particular patient with a corresponding zone identified in the displayed graphical anatomical image. A data processor uses the repository and receives data entered by a user via a displayed form and stores the entered data in a patient medical record of the particular patient.
摘要:
The present invention is directed to novel 1,2,4-thiadiazol-2-ium derivatives useful as agonists or antagonists of the melanocortin receptor. More particularly, the compounds of the present invention are useful for the treatment of metabolic, CNS and dermatological disorders such as obesity, impaired oral glucose tolerance, elevated blood glucose levels, type II diabetes, Syndrome X, diabetic retinopathy, spinal cord injury, nerve injury, acute neurodegenerative disorders, chronic neurodegenerative disorders, plexopathies, male erectile dysfunction, dry eyes, acne, dry skin, aged skin, seborrheic dermatitis, rosacea, excessive ear wax, meibomian gland disorder, pseudofolliculitis, yeast infections, dandruff, hidradenitis suppurativa, ocular rosacea and eccrine gland disorder.