-
公开(公告)号：US20080004479A1
公开(公告)日：2008-01-03
申请号：US11820238
申请日：2007-06-18
申请人： Daren Stewart , Paul Lovoi , Thomas Rusch , Alex Lim , Darius Francescatti
发明人： Daren Stewart , Paul Lovoi , Thomas Rusch , Alex Lim , Darius Francescatti
IPC分类号： A61N5/00
CPC分类号： A61N5/1015 , A61B90/39 , A61B2017/22051 , A61B2090/3933 , A61N2005/1003 , A61N2005/1061
摘要： Methods and apparatus are described for irradiating living tissue via a cavity or lumen, using an inflatable balloon applicator. In a preferred embodiment the applicator balloon has a balloon skin with x-ray contrast material in relatively low concentration, so that an outline of the balloon will appear sharply when imaged externally. In another preferred embodiment the balloon catheter has a drain for withdrawing liquids from the cavity, which may include channels or texture on the exterior of the balloon. Methods are described for using a switchable miniature x-ray tube, variable as to voltage and current, to achieve accuracy in an isodose profile.
摘要翻译： 描述了用于通过空腔或内腔照射活组织的方法和装置，使用可充气球囊施放器。 在优选实施例中，施放器气球具有具有相对较低浓度的x射线造影材料的气球皮肤，使得当从外部成像时气球的轮廓将显现出明显。 在另一个优选实施例中，球囊导管具有用于从空腔抽出液体的排水口，其可以包括气囊外部上的通道或纹理。 描述了使用可变形的微型X射线管的方法，其可变电压和电流，以获得等剂量曲线的精度。
-
公开(公告)号：US20050080313A1
公开(公告)日：2005-04-14
申请号：US10683885
申请日：2003-10-10
申请人： Daren Stewart , Paul Lovoi , Thomas Rusch , Alex Lim , Darius Francescatti
发明人： Daren Stewart , Paul Lovoi , Thomas Rusch , Alex Lim , Darius Francescatti
CPC分类号： A61N5/1015 , A61M25/1002 , A61M2025/0008 , A61M2025/1086 , A61M2210/1007 , A61N2005/1018
摘要： An applicator for facilitating radiation treatment in a body cavity, particularly post resection, provides for superior wound closure management, with an integrated drain and a flexible main shaft that permits further treatments at intervals without disturbing the wound closure. The drain includes channels in the shaft, and the surface of an expandable balloon of the applicator may have features that help channel the flow of drain liquids toward the cavity entrance. Non-spherical, irregular geometries of balloons are achieved in several different ways. In some embodiments multiple balloons are included, either an inner and outer balloon or a series of balloons extending outwardly from the main shaft. Non-balloon applicators are also disclosed.
摘要翻译： 用于促进体腔中辐射治疗，特别是后切除术的施用器提供了优异的创伤闭合管理，具有集成的排水管和柔性主轴，其允许间隔进一步的治疗而不干扰伤口闭合。 排水口包括轴中的通道，并且施加器的可膨胀气囊的表面可以具有帮助将排出液体流向空腔入口的特征。 气球的非球形，不规则几何形状以几种不同的方式实现。 在一些实施例中，包括多个气囊，内球囊和外球囊或从主轴向外延伸的一系列气球。 还公开了无气球涂抹器。
-
公开(公告)号：US20050080340A1
公开(公告)日：2005-04-14
申请号：US10962247
申请日：2004-10-08
申请人： Daren Stewart , Paul Lovoi , Thomas Rusch , Alex Lim , Darius Francescatti
发明人： Daren Stewart , Paul Lovoi , Thomas Rusch , Alex Lim , Darius Francescatti
IPC分类号： A61B5/00 , A61B6/00 , A61B17/22 , A61B19/00 , A61M25/00 , A61M36/00 , A61N20060101 , A61N5/10
CPC分类号： A61N5/1015 , A61B90/39 , A61B2017/22051 , A61B2090/3933 , A61N2005/1003 , A61N2005/1061
摘要： Methods and apparatus are described for irradiating living tissue via a cavity or lumen, using an inflatable balloon applicator. In a preferred embodiment the applicator balloon has a balloon skin with x-ray contrast material in relatively low concentration, so that an outline of the balloon will appear sharply when imaged externally. In another preferred embodiment the balloon catheter has a drain for withdrawing liquids from the cavity, which may include channels or texture on the exterior of the balloon. Methods are described for using a switchable miniature x-ray tube, variable as to voltage and current, to achieve accuracy in an isodose profile.
摘要翻译： 描述了用于通过空腔或内腔照射活组织的方法和装置，使用可充气球囊施放器。 在优选实施例中，施放器气球具有具有相对较低浓度的x射线造影材料的气球皮肤，使得当从外部成像时气球的轮廓将显现出明显。 在另一个优选实施例中，球囊导管具有用于从空腔抽出液体的排水口，其可以包括气囊外部上的通道或纹理。 描述了使用可变形的微型X射线管的方法，其可变电压和电流，以获得等剂量曲线的精度。
-
公开(公告)号：US07783006B2
公开(公告)日：2010-08-24
申请号：US10962247
申请日：2004-10-08
IPC分类号： G21K5/00
CPC分类号： A61N5/1015 , A61B90/39 , A61B2017/22051 , A61B2090/3933 , A61N2005/1003 , A61N2005/1061
摘要： Methods and apparatus are described for irradiating living tissue via a cavity or lumen, using an inflatable balloon applicator. In a preferred embodiment the applicator balloon has a balloon skin with x-ray contrast material in relatively low concentration, so that an outline of the balloon will appear sharply when imaged externally. In another preferred embodiment the balloon catheter has a drain for withdrawing liquids from the cavity, which may include channels or texture on the exterior of the balloon. Methods are described for using a switchable miniature x-ray tube, variable as to voltage and current, to achieve accuracy in an isodose profile.
摘要翻译： 描述了用于通过空腔或内腔照射活组织的方法和装置，使用可充气球囊施放器。 在优选实施例中，施放器气球具有具有相对较低浓度的x射线造影材料的气球皮肤，使得当从外部成像时气球的轮廓将显现出明显。 在另一个优选实施例中，球囊导管具有用于从空腔抽出液体的排水口，其可以包括气囊外部上的通道或纹理。 描述了使用可变形的微型X射线管的方法，其可变电压和电流，以获得等剂量曲线的精度。
-
公开(公告)号：US07885382B2
公开(公告)日：2011-02-08
申请号：US11820238
申请日：2007-06-18
IPC分类号： G21K5/00
CPC分类号： A61N5/1015 , A61B90/39 , A61B2017/22051 , A61B2090/3933 , A61N2005/1003 , A61N2005/1061
摘要： Methods and apparatus are described for irradiating living tissue via a cavity or lumen, using an inflatable balloon applicator. In a preferred embodiment the applicator balloon has a balloon skin with x-ray contrast material in relatively low concentration, so that an outline of the balloon will appear sharply when imaged externally. In another preferred embodiment the balloon catheter has a drain for withdrawing liquids from the cavity, which may include channels or texture on the exterior of the balloon. Methods are described for using a switchable miniature x-ray tube, variable as to voltage and current, to achieve accuracy in an isodose profile.
摘要翻译： 描述了用于通过空腔或内腔照射活组织的方法和装置，使用可充气球囊施放器。 在优选实施例中，施放器气球具有具有相对较低浓度的x射线造影材料的气球皮肤，使得当从外部成像时气球的轮廓将显现出明显。 在另一个优选实施例中，球囊导管具有用于从空腔抽出液体的排水口，其可以包括气囊外部上的通道或纹理。 描述了使用可变形的微型X射线管的方法，其可变电压和电流，以获得等剂量曲线的精度。
-
6.发明授权Applicators and methods for intraoperative treatment of proliferative diseases of the breast 有权用于术中治疗乳腺增殖性疾病的应用者和方法公开(公告)号：US08303476B2
公开(公告)日：2012-11-06
申请号：US12156298
申请日：2008-05-30
IPC分类号： A61N5/01
CPC分类号： A61N5/1015 , A61N5/1043 , A61N5/1083
摘要： A device for administering brachytherapy to a patient includes a vessel that may be in the form of a hollow cylindrical cup, for fleshing into and substantially filling the open-ended cavity. The vessel has a closed outer end, which may be a removable cover, and a source guide penetrates the closed outer end so as to extend deep into the vessel, to receive a radiation source in the source guide. A manipulator can be connected to the radiation source, and also to the source guide, for allowing several different types of manipulation of the source orientation and position within the vessel during the brachytherapy procedure.
摘要翻译： 用于向患者施行近距离放射疗法的装置包括可以是中空圆柱形杯形式的容器，用于充满开口腔并基本上填充开口腔。 容器具有封闭的外端，其可以是可移除的盖，并且源引导件穿过封闭的外端，以便深入到容器中，以在源引导件中接收辐射源。 操纵器可以连接到辐射源以及源引导件，用于允许在近距离放射治疗过程期间几何不同类型的源取向和容器内的位置的操纵。
-
公开(公告)号：US20090209802A1
公开(公告)日：2009-08-20
申请号：US11871116
申请日：2007-10-11
申请人： Darius Francescatti , David J. Hoffmann , Scott Tremberth , Michael Klein , Paul A. Lovoi , James E. Jervis
发明人： Darius Francescatti , David J. Hoffmann , Scott Tremberth , Michael Klein , Paul A. Lovoi , James E. Jervis
IPC分类号： A61N5/00
CPC分类号： A61N5/1015 , A61M2025/1063
摘要： Methods and applicator apparatus are disclosed for brachytherapy treatment of tissue surrounding a cavity in a patient, particularly a resection cavity. In treatment regimes requiring recovery time between successive radiation treatments, applicators of the invention are retained under the skin, with the skin allowed to at least partially heal, and are re-accessed later for one or more subsequent treatments. To reduce patient discomfort an anesthetic agent can be infused through the applicator to patient tissue, for insertion, balloon inflation or removal of the applicator.
摘要翻译： 公开了用于近距离放射治疗患者，特别是切除腔中的腔周围的组织的方法和施用装置。 在需要在连续辐射治疗之间恢复时间的治疗方案中，本发明的施用器保留在皮肤下，允许皮肤至少部分愈合，并且稍后重新进行一次或多次随后的治疗。 为了减少患者的不适，麻醉剂可以通过施用器输注到患者组织，用于插入，球囊充气或去除涂抹器。
-
公开(公告)号：US07571728B2
公开(公告)日：2009-08-11
申请号：US10820433
申请日：2004-04-08
IPC分类号： A61B19/00
CPC分类号： A61B10/0041 , A61B6/502 , A61B2090/3908
摘要： A system and method to position and orient an excised breast tissue specimen on a support structure in a duplicate anatomic orientation relative to the operated breast is provided. One embodiment of the system includes an anatomically representative map of the breast under investigation. The system allows a surgeon to suture, ink, or otherwise fix the excised specimen on the map in accordance to its original position and orientation in the operated breast or organ. A radiogram of the excised specimen can be taken that shows the location of calcifications on a grid with radiopaque markers. The system allows a pathologist to cut through the specimen utilizing the map as a template in order to perform histological analysis and correlate the position and orientation of each slice to its anatomic position in the breast and thereby direct a precise and anatomically accurate re-excision by the surgeon if so required.
摘要翻译： 提供了一种系统和方法，用于将切除的乳房组织样本定位和定向在相对于被操作的乳房的重复解剖方向的支撑结构上。 该系统的一个实施例包括正在调查的乳房的解剖学代表性的地图。 该系统允许外科医生根据其在操作的乳房或器官中的原始位置和取向缝合，油墨或以其他方式将切除的样本固定在地图上。 可以采取切除标本的放射线图，显示在具有不透射线标记的网格上钙化的位置。 该系统允许病理学家通过使用地图作为模板切割样本，以便进行组织学分析，并将每个切片的位置和取向与其在乳房中的解剖位置相关联，从而通过以下方式指导精确和解剖学上准确的再切除 外科医生如果需要的话。
-
公开(公告)号：US07727137B2
公开(公告)日：2010-06-01
申请号：US11871116
申请日：2007-10-11
申请人： Darius Francescatti , David J. Hoffmann , Scott Tremberth , Michael Klein , Paul A. Lovoi , James E. Jervis
发明人： Darius Francescatti , David J. Hoffmann , Scott Tremberth , Michael Klein , Paul A. Lovoi , James E. Jervis
CPC分类号： A61N5/1015 , A61M2025/1063
摘要： Methods and applicator apparatus are disclosed for brachytherapy treatment of tissue surrounding a cavity in a patient, particularly a resection cavity. In treatment regimes requiring recovery time between successive radiation treatments, applicators of the invention are retained under the skin, with the skin allowed to at least partially heal, and are re-accessed later for one or more subsequent treatments. To reduce patient discomfort an anesthetic agent can be infused through the applicator to patient tissue, for insertion, balloon inflation or removal of the applicator.
摘要翻译： 公开了用于近距离放射治疗患者，特别是切除腔中的腔周围的组织的方法和施用装置。 在需要在连续辐射治疗之间恢复时间的治疗方案中，本发明的施用器保留在皮肤下，允许皮肤至少部分愈合，并且稍后重新进行一次或多次随后的治疗。 为了减少患者的不适，麻醉剂可以通过施用器输注到患者组织，用于插入，球囊充气或去除涂抹器。
-
公开(公告)号：US07726318B2
公开(公告)日：2010-06-01
申请号：US11385255
申请日：2006-03-20
CPC分类号： A61N5/1015 , A61B90/04 , A61B2090/0445 , A61N2005/1094
摘要： A flexible, relatively flat and thin patch, optionally made of biodegradable material, substantially attenuates ionizing radiation from normal but sensitive anatomy during radio-therapy, particularly breast brachytherapy. The patch is of such a thickness as to substantially attenuate radiation by distance or consists of a material that has been formulated with radio-attenuating filler or is of radio-attenuating material. An alternative version consists of a thin patch that is coated with radio-attenuating material.
摘要翻译： 可选地由可生物降解材料制成的柔性，相对平坦和薄的贴片在放射治疗期间，特别是乳房近距离放射治疗中，基本上减弱了来自正常但敏感的解剖结构的电离辐射。 该贴片具有如此厚度以使辐射基本上被距离缩短或由已经用无线电衰减填料配制的材料或具有无线电衰减材料的材料组成。 替代版本由涂有无线电衰减材料的薄贴片组成。
-
-
-
-
-
-
-
-
-
搜索结果
23 条记录 (耗时 0.021 秒)
