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    Enteral formulation designed for optimized wound healing
    4.
    发明授权
    Enteral formulation designed for optimized wound healing 失效
    肠内制剂设计用于优化伤口愈合

    公开(公告)号：US5733884A

    公开(公告)日：1998-03-31

    申请号：US554475

    申请日：1995-11-07

    申请人： Adrian Barbul ,  Lisa Stewart Bebenek ,  David A. Mark ,  Susan Trimbo ,  Diana Twyman ,  Paul Lin

    发明人： Adrian Barbul ,  Lisa Stewart Bebenek ,  David A. Mark ,  Susan Trimbo ,  Diana Twyman ,  Paul Lin

    IPC分类号： A23G3/00 ,  A23G3/36 ,  A23L1/29 ,  A23L1/30 ,  A23L1/302 ,  A61K38/01 ,  A61K38/00 ,  A23J1/00

    CPC分类号： A23G3/368 ,  A23L33/12 ,  A23L33/15 ,  A23L33/40 ,  A61K38/01 ,  A23V2002/00 ,  Y10S514/943

    摘要： The present invention provides an enteral nutritional formulation that meets the nutrient requirements of patients with wounds. The present invention meets the unique nutrient needs of the acute or chronic patient that are generated due to tissue repair and healing requirements of wounds. To this end, in an embodiment, the present invention provides a method for providing nutritional support to a patient with an acute or chronic wound comprising the step of administering a therapeutically effective amount of composition comprising a protein source including an arginine source and a proline source in the ratio by weight of approximately 1:0.5 to about 4:1. The composition may also include a carbohydrate source, a lipid source including an appropriate n6:n3 ratio, and at least the U.S. RDA for vitamins and minerals provided in an amount of formula supplying 1000 kcal, with vitamin A, beta-carotene, vitamin C, vitamin E, thiamine, pyridoxine, biotin and zinc being supplied in amounts above the U.S. RDAs.

    摘要翻译： 本发明提供了能够满足伤口患者营养需求的肠内营养制剂。 本发明满足由于组织修复和伤口愈合要求而产生的急性或慢性患者的独特的营养需求。 为此，在一个实施方案中，本发明提供了一种用于向患有急性或慢性伤口的患者提供营养支持的方法，包括施用治疗有效量的组合物的步骤，所述组合物包含蛋白质源，所述蛋白源包括精氨酸源和脯氨酸来源 重量比为约1:0.5至约4:1。 组合物还可以包括碳水化合物源，包括适当的n6：n3比例的脂质源，至少提供以供给1000千卡的配方的维生素和矿物质的美国RDA，维生素A，β-胡萝卜素，维生素C ，维生素E，硫胺素，吡哆醇，生物素和锌的供应量高于美国RDAs。

    Enternal formulation designed for optimized nutrient absorption and wound healing
    5.
    发明授权
    Enternal formulation designed for optimized nutrient absorption and wound healing 失效
    设计用于优化营养吸收和伤口愈合的内在配方

    公开(公告)号：US5714472A

    公开(公告)日：1998-02-03

    申请号：US530877

    申请日：1995-09-20

    申请人： Debora Gray ,  Nancy S. Schmelkin ,  John Alexander ,  David A. Mark ,  Diana Twyman

    发明人： Debora Gray ,  Nancy S. Schmelkin ,  John Alexander ,  David A. Mark ,  Diana Twyman

    IPC分类号： A23L1/29 ,  A23L1/30 ,  A23L1/305 ,  A61K38/00 ,  A23G3/00 ,  A23J1/00

    CPC分类号： A23L33/18 ,  A23L33/12 ,  A23L33/40 ,  Y10S424/13 ,  Y10S514/943

    摘要： The present invention provides an enteral nutritional formulation that meets the nutrient requirements of intensive care patients who may have compromised absorption capacity. The present invention meets the unique nutrient needs of the patient that are generated due to tissue repair and healing requirements. To this end, in an embodiment the present invention provides a method for providing nutritional support to intensive care patients comprising the steps of administering a therapeutically effective amount of a composition comprising: a protein source; a carbohydrate source; and a lipid source including a source of medium chain triglycerides, a source of omega-3 fatty acids, and a source of omega-6 fatty acids.

    摘要翻译： 本发明提供一种能够满足可能损害吸收能力的重症监护病人的营养需求的肠内营养制剂。 本发明满足由于组织修复和愈合要求而产生的患者的独特的营养需求。 为此，在一个实施方案中，本发明提供了一种向重症监护病人提供营养支持的方法，包括施用治疗有效量的组合物的步骤，所述组合物包含：蛋白质来源; 碳水化合物来源; 以及包含中链甘油三酸酯源，ω-3脂肪酸源和ω-6脂肪酸来源的脂质源。

    Enteral formulation designed for optimized nutrient absorption and wound healing
    6.
    发明授权
    Enteral formulation designed for optimized nutrient absorption and wound healing 失效
    肠内制剂设计用于优化营养吸收和伤口愈合

    公开(公告)号：US5723446A

    公开(公告)日：1998-03-03

    申请号：US680703

    申请日：1996-07-17

    申请人： Debora Gray ,  Nancy S. Schmelkin ,  John Alexander ,  David A. Mark ,  Diana Twyman

    发明人： Debora Gray ,  Nancy S. Schmelkin ,  John Alexander ,  David A. Mark ,  Diana Twyman

    IPC分类号： A23G3/00 ,  A23G3/36 ,  A23G3/44 ,  A23J3/32 ,  A61K38/01 ,  A61K38/00 ,  A23J1/00

    CPC分类号： A23G3/44 ,  A23G3/368 ,  A23J3/325 ,  A61K38/01 ,  Y10S424/13 ,  Y10S514/943

    摘要： The present invention provides an enteral nutritional formulation that meets the nutrient requirements of intensive care patients who may have compromised absorption capacity. The present invention meets the unique nutrient needs of the patient that are generated due to tissue repair and healing requirements. To this end, in an embodiment the present invention provides a method for treating and/or providing nutritional support to intensive care patients comprising the steps of administering a therapeutically effective amount of a composition comprising: a protein source; a carbohydrate source; and a lipid source including a source of medium chain triglycerides, a source of omega-3 fatty acids, and a source of omega-6 fatty acids.

    摘要翻译： 本发明提供一种能够满足可能损害吸收能力的重症监护病人的营养需求的肠内营养制剂。 本发明满足由于组织修复和愈合要求而产生的患者的独特的营养需求。 为此，在一个实施方案中，本发明提供了一种治疗和/或为重症监护病人提供营养支持的方法，包括以下步骤：施用治疗有效量的组合物，所述组合物包含：蛋白质来源; 碳水化合物来源; 以及包含中链甘油三酸酯源，ω-3脂肪酸源和ω-6脂肪酸来源的脂质源。

    Enternal composition for pediatric patients
    7.
    发明授权
    Enternal composition for pediatric patients 失效
    儿科患者的完整成分

    公开(公告)号：US5549905A

    公开(公告)日：1996-08-27

    申请号：US324727

    申请日：1994-10-18

    申请人： David A. Mark ,  Diana Twyman ,  Donna Buckley

    发明人： David A. Mark ,  Diana Twyman ,  Donna Buckley

    IPC分类号： A23L1/30 ,  A23L1/305 ,  A61K47/00

    CPC分类号： A23L33/18 ,  A23L33/12

    摘要： The present invention provides a method and nutritional composition for providing nutrition to pediatric patients. The methods of the present invention are directed to pediatric patients with impaired nutrient absorption and/or reduced gastrointestinal tolerance. Pursuant to the present invention, the enteral composition includes a hydrolyzed protein source comprising approximately 12% of the total calories, a carbohydrate source and a lipid source comprising a mixture of medium and long chain triglycerides, wherein at least 55% of the lipid source are medium chain triglycerides.

    摘要翻译： 本发明提供了一种为儿科患者提供营养的方法和营养组合物。 本发明的方法涉及营养吸收受损和/或胃肠耐受性降低的儿科患者。 根据本发明，肠内组合物包括包含总卡路里的约12％的水解蛋白源，碳水化合物源和包含中长链甘油三酯的混合物的脂质源，其中至少55％的脂质来源是 中链甘油三酸酯。

    Enteral composition for malabsorbing patients
    8.
    发明授权
    Enteral composition for malabsorbing patients 失效
    用于吸收不良患者的肠内成分

    公开(公告)号：US5661123A

    公开(公告)日：1997-08-26

    申请号：US372980

    申请日：1995-01-17

    申请人： Lance Stalker ,  Diana Twyman ,  Shen-Youn Chang ,  Veronique Jaussan

    发明人： Lance Stalker ,  Diana Twyman ,  Shen-Youn Chang ,  Veronique Jaussan

    IPC分类号： A61K38/01 ,  A61K31/015 ,  A61K31/11 ,  A61K31/12 ,  A61K31/14 ,  A61K31/185 ,  A61K31/20 ,  A61K31/205 ,  A61K31/225 ,  A61K31/34 ,  A61K31/70

    CPC分类号： A61K38/018

    摘要： The present invention provides a method for providing nutrition to non-catabolic and moderately catabolic patients. Pursuant to the present invention, the enteral composition includes a peptide based protein source of hydrolyzed whey, a lipid source, and a carbohydrate source. Preferably, the protein source includes approximately 22% to about 27% of the total calories. The composition has a caloric density of approximately 1000 Kcal/L and a low osmolality of approximately 300 to 450 mOsm/Kg H.sub.2 O. Still further, the composition of the present invention also includes increased levels of certain vitamins and minerals.

    摘要翻译： 本发明提供了一种为非分解代谢和中度分解代谢患者提供营养的方法。 根据本发明，肠内组合物包括水解乳清的肽基蛋白质来源，脂质源和碳水化合物源。 优选地，蛋白质源包括总热量的约22％至约27％。 该组合物具有约1000千卡/升的热密度和约300至450mOsm / KgH 2 O的低渗透压。 此外，本发明的组合物还包括某些维生素和矿物质的增加的水平。