公开(公告)号：US20090099617A1

公开(公告)日：2009-04-16

申请号：US11873292

申请日：2007-10-16

申请人： David F. Hastings ,  Xin Good ,  Volker Lang

发明人： David F. Hastings ,  Xin Good ,  Volker Lang

IPC分类号： A61N1/365

CPC分类号： A61N1/362

摘要： An implantable medical device that continuously measures the patient's intracardiac ventricular impedance. Extracts cardiac performance information based on the intracardiac impedance, including amplitude, timing and variability of cardiac contraction function. The device records and analyses trends in the performance information. The device identifies changes, which exceed the selected threshold limits. In the event of an incipient crisis, the device transmits an alert message.

摘要翻译： 可植入的医疗装置，可持续测量患者的心内心室阻抗。 基于心脏内阻抗提取心脏性能信息，包括心脏收缩功能的幅度，时间和变异性。 设备记录和分析性能信息的趋势。 设备识别出超出选定阈值限制的更改。 在发生初期危机的情况下，设备会发送警报消息。

公开(公告)号：US08649864B2

公开(公告)日：2014-02-11

申请号：US11873292

申请日：2007-10-16

申请人： David F. Hastings ,  Xin Good ,  Volker Lang

发明人： David F. Hastings ,  Xin Good ,  Volker Lang

IPC分类号： A61N1/365

CPC分类号： A61N1/362

摘要： An implantable medical device that continuously measures the patient's intracardiac ventricular impedance. Extracts cardiac performance information based on the intracardiac impedance, including amplitude, timing and variability of cardiac contraction function. The device records and analysis trends in the performance information. The device identifies changes, which exceed the selected threshold limits. In the event of an incipient crisis, the device transmits an alert message.

摘要翻译： 可植入的医疗装置，可持续测量患者的心内心室阻抗。 基于心脏内阻抗提取心脏性能信息，包括心脏收缩功能的幅度，时间和变异性。 设备记录和分析性能信息的趋势。 设备识别出超出选定阈值限制的更改。 在发生初期危机的情况下，设备会发送警报消息。

公开(公告)号：US20140360982A1

公开(公告)日：2014-12-11

申请号：US14366010

申请日：2012-12-12

申请人： Karsten Gerving ,  Volker Lang ,  Johannes Meissner ,  Ralf Thar

发明人： Karsten Gerving ,  Volker Lang ,  Johannes Meissner ,  Ralf Thar

IPC分类号： H01H33/18 ,  H01H33/20 ,  H01H33/10

CPC分类号： H01H33/182 ,  H01H9/362 ,  H01H9/443 ,  H01H9/46 ,  H01H33/10 ,  H01H33/20

摘要： A switching device suitable for DC operation includes at least one pair of contacts having a first contact and a second contact, wherein at least one of the two contacts is mobile and the two contacts are in contact with one another in a switched-on state of the switching device and are not in contact with one another in a switched-off state of the switching device, further having an arc driver arrangement for generating a magnetic field and an arc guiding arrangement for guiding an arc, which is produced between the contacts, to a quenching device. The problem of quenching arcs independently of the current direction in just one individual quenching apparatus in each case is solved with a substantially homogeneous magnetic field which is generated by permanent magnets.

摘要翻译： 适用于直流操作的开关装置包括具有第一触点和第二触点的至少一对触点，其中两个触点中的至少一个触点是可移动的，并且两个触点在接通状态下彼此接触 切换装置并且在切换装置的关闭状态下彼此不接触，还具有用于产生磁场的电弧驱动装置和用于引导在触点之间产生的电弧的电弧引导装置， 到淬火装置。 在每种情况下，仅在一个单独的淬火装置中独立于电流方向的电弧的问题就由永磁体产生的基本均匀的磁场来解决。

公开(公告)号：US08843198B2

公开(公告)日：2014-09-23

申请号：US13603418

申请日：2012-09-05

申请人： Jie Lian ,  Volker Lang ,  Hannes Kraetschmer ,  Dirk Muessig

发明人： Jie Lian ,  Volker Lang ,  Hannes Kraetschmer ,  Dirk Muessig

IPC分类号： A61N1/368 ,  A61B5/04 ,  A61N1/365 ,  A61N1/362 ,  A61B5/0402

CPC分类号： A61N1/3627 ,  A61B5/0402 ,  A61N1/36521 ,  A61N1/3682 ,  A61N1/3684 ,  A61N1/3686

摘要： The present disclosure refers to a heart stimulator comprising a stimulation control unit, a stimulation unit, an impedance measurement unit and an impedance evaluation unit. The stimulation control unit is operatively connected to the stimulation unit to control timing of stimulation pulses by said stimulation unit. The impedance measurement unit is configured to determine an impedance signal reflecting intracardiac impedance. The impedance evaluation unit is operatively connected to the impedance measurement unit and to the stimulation control unit and is configured to evaluate the impedance signal so as to determine an isovolumic contraction time, an isovolumic relaxation time, an ejection time and a filling time from said impedance signal. The stimulation control unit is further configured to control timing of stimulation pulses depending on a performance index.

摘要翻译： 本公开涉及包括刺激控制单元，刺激单元，阻抗测量单元和阻抗评估单元的心脏刺激器。 刺激控制单元可操作地连接到刺激单元以控制所述刺激单元的刺激脉冲的定时。 阻抗测量单元被配置为确定反映心内阻抗的阻抗信号。 阻抗评估单元可操作地连接到阻抗测量单元和刺激控制单元，并被配置为评估阻抗信号，以便确定等容收缩时间，等容弛豫时间，喷射时间和来自所述阻抗的填充时间 信号。 刺激控制单元还被配置为根据性能指标来控制刺激脉冲的定时。

公开(公告)号：US20130313228A1

公开(公告)日：2013-11-28

申请号：US13992278

申请日：2011-12-07

申请人： Lutz Friedrichsen ,  Volker Lang

发明人： Lutz Friedrichsen ,  Volker Lang

IPC分类号： H01H33/18

CPC分类号： H01H33/182 ,  H01H1/20 ,  H01H9/346 ,  H01H9/443 ,  H01H33/596

摘要： A switch for polarity-independent direct current operation includes fixed contacts, each including a first contact area. A movable bridge contact with second contact areas is configured to form an electrically conducting connection between the contact areas in an ON state and to separate the contact areas in an OFF state. A magnetic field exerts a magnetic force on an arc occurring between the contact areas when the OFF state is generated. Quenching chambers are provided to quench arcs with a first current direction. A first arc deflector plate extends from each of the quenching chambers toward the first contact area and a second arc deflector plate extends toward the second contact area for removing the arc into the quenching chambers. Each movable bridge contact includes two bridge plates which extend around each of the first contact areas so as to quench arcs in a second direction.

摘要翻译： 用于极性独立直流操作的开关包括固定触点，每个包括第一接触区域。 与第二接触区域的可移动桥接触构造成在接通状态之间的接触区域之间形成导电连接，并将接触区域分离成断开状态。 当产生OFF状态时，磁场对接触区域之间发生的电弧施加磁力。 提供淬火室以使第一电流方向骤冷。 第一弧形偏转板从每个淬火室朝向第一接触区域延伸，并且第二弧形偏转板朝向第二接触区域延伸，以将电弧移除到淬火室中。 每个可移动桥接器包括两个桥板，它们围绕每个第一接触区域延伸，以在第二方向上淬火。

公开(公告)号：US08380307B2

公开(公告)日：2013-02-19

申请号：US12255516

申请日：2008-10-21

申请人： Jie Lian ,  Garth Garner ,  Dirk Muessig ,  Volker Lang

发明人： Jie Lian ,  Garth Garner ,  Dirk Muessig ,  Volker Lang

IPC分类号： A61N1/00

CPC分类号： A61N1/3627 ,  A61N1/3688

摘要： The invention is directed to a heart stimulator for left-ventricular pacing comprising a left ventricular stimulation pulse generator connected or connectable to a single electrode lead for left ventricular stimulation having one or more electrodes for delivery of stimulation pulses to left ventricular myocardial heart tissue, said stimulation pulse generator being adapted to generate and deliver stimulation pulses of switchable polarity. The heart stimulator further comprises a control unit connected to the stimulation pulse generator for controlling the stimulation pulse generator and to trigger generation and delivery of stimulation pulses having a polarity controlled by said control unit, wherein the control unit is adapted to control said left ventricular stimulation pulse generator so as to deliver at least a pair of suprathreshold stimulation pulses of opposite polarity.

摘要翻译： 本发明涉及用于左心室起搏的心脏刺激器，其包括连接或可连接到用于左心室刺激的单个电极引线的左心室刺激脉冲发生器，其具有用于将刺激脉冲递送至左心室心肌心脏组织的一个或多个电极，所述左心室起搏器 刺激脉冲发生器适于产生和递送可切换极性的刺激脉冲。 心脏刺激器还包括连接到刺激脉冲发生器的控制单元，用于控制刺激脉冲发生器并触发具有由所述控制单元控制的极性的刺激脉冲的产生和传递，其中控制单元适于控制所述左心室刺激 以产生相反极性的至少一对超阈值刺激脉冲。

公开(公告)号：US07915985B2

公开(公告)日：2011-03-29

申请号：US12271562

申请日：2008-11-14

申请人： Gerd Schmitz ,  Volker Lang ,  Wolfgang Kremers ,  Lothar Winzen

发明人： Gerd Schmitz ,  Volker Lang ,  Wolfgang Kremers ,  Lothar Winzen

IPC分类号： H01H9/30 ,  H01H9/02 ,  H01H13/04 ,  H01H9/44 ,  H01H33/18

CPC分类号： H01H9/443 ,  H01H1/20 ,  H01H9/36

摘要： A switching device for direct-current applications includes a housing having a first wall and a second wall, a plurality of receiving areas for respective mutually substantially parallel current paths disposed in the housing. Each of the current paths has a respective stationary switching contact element and a respective movable switching contact element, the movable switching element being actuatable into a closed position and into an open position so as to form a respective air break, the respective movable switching contact elements being actuatable simultaneously. The switching device includes a plurality of arc-quenching devices associated with the current paths and disposed next to each other, and at least one magnet. The at least one magnet is configured to generate a magnetic field so as to generate a deflection force on the arcs so as to deflect the respective arcs toward at least one of the respective arc-quenching devices.

摘要翻译： 用于直流应用的开关装置包括具有第一壁和第二壁的壳体，用于设置在壳体中的各个相互基本平行的电流路径的多个接收区域。 每个电流路径具有相应的固定开关接触元件和相应的可移动开关触点元件，可移动开关元件可致动到关闭位置并进入打开位置以形成相应的空气断路，各个可移动开关触点元件 可同时启动。 切换装置包括与电流路径相关联并彼此相邻布置的多个灭弧装置和至少一个磁体。 所述至少一个磁体被配置为产生磁场，以便在所述电弧上产生偏转力，以便使各个弧朝着相应的灭弧装置中的至少一个偏转。

公开(公告)号：US07899520B2

公开(公告)日：2011-03-01

申请号：US12124499

申请日：2008-05-21

申请人： Jie Lian ,  Garth Garner ,  Dirk Muessig ,  Volker Lang

发明人： Jie Lian ,  Garth Garner ,  Dirk Muessig ,  Volker Lang

IPC分类号： A61B5/04

CPC分类号： G06K9/00496 ,  A61N1/3684 ,  A61N1/3712 ,  G06K9/00536

摘要： A medical device having a sensor for sampling a biological signal, the biological signal representing a signal waveform and forming a waveform vector composed of the biological signal samples, and a memory for storing a least two threshold vectors composed of boundary samples representing at least two boundaries related to the biological signal defining subspaces for the biological signal samples. One threshold vector is an upper threshold vector composed of upper boundary samples and the other threshold vector is a lower threshold vector composed of lower boundary samples. An evaluation unit connected to the sensor determines a similarity index (ASCI) by comparing each of the biological signal samples of the waveform vector to corresponding boundary samples of the threshold vectors, thus determining to which subspace each biological signal sample belongs to and creating a trichotomized signal vector, and calculating the signed correlation product of two trichotomized signal vectors.

摘要翻译： 一种具有用于对生物体信号进行采样的传感器的医疗装置，生物信号表示信号波形并形成由生物信号样本构成的波形矢量，以及存储器，用于存储由表示至少两个边界的边界样本组成的至少两个阈值向量 与生物信号样品的生物信号定义子空间有关。 一个阈值向量是由上边界样本组成的上阈值向量，另一阈值向量是由下边界样本组成的下阈值向量。 连接到传感器的评估单元通过将波形向量的生物信号样本与阈值向量的相应边界样本进行比较来确定相似性指数（ASCI），从而确定每个生物信号样本属于哪个子空间并创建三分法 信号向量，并计算两个三分信号向量的有符号相关乘积。

公开(公告)号：US20080294217A1

公开(公告)日：2008-11-27

申请号：US12124499

申请日：2008-05-21

申请人： Jie Lian ,  Garth Garner ,  Dirk Muessig ,  Volker Lang

发明人： Jie Lian ,  Garth Garner ,  Dirk Muessig ,  Volker Lang

IPC分类号： A61N1/368 ,  A61B5/00

CPC分类号： G06K9/00496 ,  A61N1/3684 ,  A61N1/3712 ,  G06K9/00536

摘要： A medical device having a sensor for sampling a biological signal, the biological signal representing a signal waveform and forming a waveform vector composed of the biological signal samples, and a memory for storing a least two threshold vectors composed of boundary samples representing at least two boundaries related to the biological signal defining subspaces for the biological signal samples. One threshold vector is an upper threshold vector composed of upper boundary samples and the other threshold vector is a lower threshold vector composed of lower boundary samples. An evaluation unit connected to the sensor determines a similarity index (ASCI) by comparing each of the biological signal samples of the waveform vector to corresponding boundary samples of the threshold vectors, thus determining to which subspace each biological signal sample belongs to and creating a trichotomized signal vector, and calculating the signed correlation product of two trichotomized signal vectors.

摘要翻译： 一种具有用于对生物体信号进行采样的传感器的医疗装置，生物信号表示信号波形并形成由生物信号样本构成的波形矢量，以及存储器，用于存储由表示至少两个边界的边界样本组成的至少两个阈值向量 与生物信号样品的生物信号定义子空间有关。 一个阈值向量是由上边界样本组成的上阈值向量，另一个阈值向量是由下边界样本组成的下阈值向量。 连接到传感器的评估单元通过将波形向量的生物信号样本与阈值向量的相应边界样本进行比较来确定相似性指数（ASCI），从而确定每个生物信号样本属于哪个子空间并创建三分法 信号矢量，并计算两个三分信号矢量的有符号相关乘积。

公开(公告)号：US20080114411A1

公开(公告)日：2008-05-15

申请号：US11560141

申请日：2006-11-15

申请人： Jie Lian ,  Dirk Muessig ,  Volker Lang

发明人： Jie Lian ,  Dirk Muessig ,  Volker Lang

IPC分类号： A61N1/365

CPC分类号： A61N1/3621 ,  A61B5/0452

摘要： Heart stimulator that provides for timing a premature stimulation pulse for anti-tachycardia pacing outside the vulnerable phase of a ventricle, to terminate stable ventricular tachycardia while minimizing the risk of accelerating stable ventricular tachycardia into unstable ventricular tachycardia or ventricular fibrillation. RT interval is determined instead of QT interval. Conventional QT interval is defined to end at T wave offset, which is difficult to measure because inherent imprecision in identifying the end of T wave from surface ECG. For safe ATP, such problems may be avoided. Because the VP usually refers to the portion of the T wave near the peak and early downslope (FIG. 3), in order to avoid the VP, only need to determine the peak of T wave, then set an blanking window or safety margin (e.g., 20 ms before to 20 ms after the peak of T wave) during which ATP pulses should not be delivered.

摘要翻译： 心脏刺激器提供定时的过早刺激脉冲，用于在心室易失性阶段之外的抗心动过速起搏，以终止稳定的室性心动过速，同时最小化加速稳定性室性心动过速到不稳定室性心动过速或心室纤维性颤动的风险。 确定RT间隔而不是QT间隔。 常规QT间隔被定义为在T波偏移处结束，这是难以测量的，因为在从表面ECG识别T波的末端的固有的不精确性。 为了安全的ATP，可以避免这样的问题。 因为VP通常是指峰值附近的T波的一部分和早期的下坡（图3），为了避免VP，只需要确定T波的峰值，则设置消隐窗口或安全裕度（ 例如，在T波峰值之前到20ms之前20ms），其中不应该递送ATP脉冲。