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1.O-LINKED PYRIMIDIN-4-AMINE-BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE TO TREAT CANCER 有权
标题翻译: O型连接的吡啶基-4-胺基化合物,包含它们的组合物及其用于治疗癌症的方法公开(公告)号:US20080146571A1
公开(公告)日:2008-06-19
申请号:US11954433
申请日:2007-12-12
申请人: David J. Augeri , Marianne Carlsen , Kenneth G. Carson , Qinghong Fu , Jason P. Healy , Alexander Heim-Riether , Theodore C. Jessop , Philip E. Keyes , Min Shen , James E. Tarver , Jerry A. Taylor , Xiaolian Xu
发明人: David J. Augeri , Marianne Carlsen , Kenneth G. Carson , Qinghong Fu , Jason P. Healy , Alexander Heim-Riether , Theodore C. Jessop , Philip E. Keyes , Min Shen , James E. Tarver , Jerry A. Taylor , Xiaolian Xu
IPC分类号: A61K31/506 , C07D239/47 , C07D403/12 , A61K31/519 , A61P35/00 , A61K31/5377 , C07D491/044 , C07D413/12
CPC分类号: C07D401/12 , C07D401/14 , C07D409/14
摘要: O-linked pyrimidin-4-amine-based compounds, pharmaceutical compositions comprising them, and methods of their use are described. Particular compounds of the invention are of formula I:
摘要翻译: 描述了O-连接的嘧啶-4-胺类化合物,包含它们的药物组合物及其使用方法。 本发明的具体化合物具有式I:
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2.O-linked pyrimidin-4-amine-based compounds, compositions comprising them, and methods of their use to treat cancer 有权
标题翻译: O-连接的嘧啶-4-胺类化合物,包含它们的组合物及其用于治疗癌症的方法公开(公告)号:US08093246B2
公开(公告)日:2012-01-10
申请号:US11954433
申请日:2007-12-12
申请人: David J. Augeri , Marianne Carlsen , Kenneth G. Carson , Qinghong Fu , Jason P. Healy , Alexander Heim-Riether , Theodore C. Jessop , Philip E. Keyes , Min Shen , James E. Tarver , Jerry A. Taylor , Xiaolian Xu
发明人: David J. Augeri , Marianne Carlsen , Kenneth G. Carson , Qinghong Fu , Jason P. Healy , Alexander Heim-Riether , Theodore C. Jessop , Philip E. Keyes , Min Shen , James E. Tarver , Jerry A. Taylor , Xiaolian Xu
IPC分类号: C07D403/14 , A61K31/506
CPC分类号: C07D401/12 , C07D401/14 , C07D409/14
摘要: O-linked pyrimidin-4-amine-based compounds, pharmaceutical compositions comprising them, and methods of their use are described. Particular compounds of the invention are of formula I:
摘要翻译: 描述了O-连接的嘧啶-4-胺类化合物,包含它们的药物组合物及其使用方法。 本发明的具体化合物具有式I:
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