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    Endoluminal stent having a matched stiffness region and/or a stiffness gradient
    1.
    发明授权
    Endoluminal stent having a matched stiffness region and/or a stiffness gradient 有权
    具有匹配刚度区域和/或刚度梯度的腔内支架

    公开(公告)号：US07722664B2

    公开(公告)日：2010-05-25

    申请号：US11735180

    申请日：2007-04-13

    申请人： David J. Zarbatany ,  Ari Moskowitz ,  Fergus Quigley ,  Lukas J. Hijlkema

    发明人： David J. Zarbatany ,  Ari Moskowitz ,  Fergus Quigley ,  Lukas J. Hijlkema

    IPC分类号： A61F2/06

    CPC分类号： A61F2/86 ,  A61F2/064 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/065 ,  A61F2002/067 ,  A61F2002/91558 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2250/0018 ,  A61F2250/0036

    摘要： A modular elongated stent having an overlap region where two modular components fit together, the overlap region being relatively stiff as compared to another more flexible region of the stent when the stent is in an assembled configuration, the stent further comprising a mimic region that has a stiffness essentially equivalent to the stiffness of the overlap region, to provide kink resistance. A stent having such a mimic region or otherwise stiff region and a flexible region may have a transition region between the stiff and flexible regions, also to provide kink resistance. A stent may have relatively stiff regions and relatively flexible regions positioned to align the flexible regions with curved regions of a body lumen when deployed within the body lumen. The stiffness of the stiff, flexible, and transition regions may be controlled by varying the cross-sectional area of the stent components and/or by varying the stent architecture.

    摘要翻译： 一种模块化细长支架，其具有两个模块化部件装配在一起的重叠区域，当所述支架处于组装构型时，所述重叠区域与所述支架的另一更柔性区域相比是相对刚性的，所述支架还包括模具区域， 刚度基本上等于重叠区域的刚度，以提供扭结阻力。 具有这种模拟区域或其他刚性区域和柔性区域的支架可以在刚性区域和柔性区域之间具有过渡区域，也提供扭结阻力。 支架可以具有相对刚性的区域和相对柔性的区域，其定位成当部署在体腔内时将柔性区域与体腔的弯曲区域对准。 可以通过改变支架部件的横截面面积和/或通过改变支架结构来控制刚性，柔性和过渡区域的刚度。

    Endoluminal stent having a matched stiffness region and/or a stiffness gradient and methods for providing stent kink resistance
    2.
    发明授权
    Endoluminal stent having a matched stiffness region and/or a stiffness gradient and methods for providing stent kink resistance 失效
    具有匹配刚度区域和/或刚度梯度的腔内支架和用于提供支架扭结阻力的方法

    公开(公告)号：US07214241B2

    公开(公告)日：2007-05-08

    申请号：US10612110

    申请日：2003-07-02

    申请人： David J. Zarbatany ,  Ari Moskowitz ,  Fergus P. Quigley ,  Lukas J. Hijlkema

    发明人： David J. Zarbatany ,  Ari Moskowitz ,  Fergus P. Quigley ,  Lukas J. Hijlkema

    IPC分类号： A61F2/06

    CPC分类号： A61F2/86 ,  A61F2/064 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/065 ,  A61F2002/067 ,  A61F2002/91558 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2250/0018 ,  A61F2250/0036

    摘要： A modular elongated stent having an overlap region where two modular components fit together, the overlap region being relatively stiff as compared to another more flexible region of the stent when the stent is in an assembled configuration, the stent further comprising a mimic region that has a stiffness essentially equivalent to the stiffness of the overlap region, to provide kink resistance. A stent having such a mimic region or otherwise stiff region and a flexible region may have a transition region between the stiff and flexible regions, such as a bridging material attached to the stent, also to provide kink resistance. A stent may have relatively stiff regions and relatively flexible regions positioned to align the flexible regions with curved regions of a body lumen when deployed within the body lumen. The stiffness of the stiff, flexible, and transition regions may be controlled by attaching material to the stent, varying the cross-sectional area of the stent components, varying the metallurgical properties thereof, and/or by varying the stent architecture. Methods for providing kink resistance by controlling stent stiffness are also disclosed. A stent having regions of different metallurgical properties is also disclosed, as are methods for creating such a stent.

    摘要翻译： 一种模块化细长支架，其具有两个模块化部件装配在一起的重叠区域，当所述支架处于组装构型时，所述重叠区域与所述支架的另一更柔性区域相比是相对刚性的，所述支架还包括模具区域， 刚度基本上等于重叠区域的刚度，以提供扭结阻力。 具有这种模拟区域或其他刚性区域和柔性区域的支架可以在刚性区域和柔性区域之间具有过渡区域，例如连接到支架的桥接材料，也提供扭结阻力。 支架可以具有相对刚性的区域和相对柔性的区域，其定位成当部署在体腔内时将柔性区域与体腔的弯曲区域对准。 可以通过将材料附接到支架，改变支架部件的横截面面积，改变其冶金特性和/或通过改变支架结构来控制刚性，柔性和过渡区域的刚度。 还公开了通过控制支架刚度提供扭结阻力的方法。 还公开了具有不同冶金特性的区域的支架，以及用于产生这种支架的方法。

    Endoluminal stent having a matched stiffness region and/or a stiffness gradient and methods for providing stent kink resistance
    3.
    发明授权
    Endoluminal stent having a matched stiffness region and/or a stiffness gradient and methods for providing stent kink resistance 失效
    具有匹配刚度区域和/或刚度梯度的腔内支架和用于提供支架扭结阻力的方法

    公开(公告)号：US06610087B1

    公开(公告)日：2003-08-26

    申请号：US09442192

    申请日：1999-11-16

    申请人： David J. Zarbatany ,  Ari Moskowitz ,  Fergus P. Quigley ,  Lukas J. Hijlkema

    发明人： David J. Zarbatany ,  Ari Moskowitz ,  Fergus P. Quigley ,  Lukas J. Hijlkema

    IPC分类号： A61F206

    CPC分类号： A61F2/86 ,  A61F2/064 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/065 ,  A61F2002/067 ,  A61F2002/91558 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2250/0018 ,  A61F2250/0036

    摘要： A modular elongated stent having an overlap region where two modular components fit together, the overlap region being relatively stiff as compared to another more flexible region of the stent when the stent is in an assembled configuration, the stent further comprising a mimic region that has a stiffness essentially equivalent to the stiffness of the overlap region, to provide kink resistance. A stent having such a mimic region or otherwise stiff region and a flexible region may have a transition region between the stiff and flexible regions, such as a bridging material attached to the stent, also to provide kink resistance. A stent may have relatively stiff regions and relatively flexible regions positioned to align the flexible regions with curved regions of a body lumen when deployed within the body lumen. The stiffness of the stiff, flexible, and transition regions may be controlled by attaching material to the stent, varying the cross-sectional area of the stent components, varying the metallurgical properties thereof, and/or by varying the stent architecture. Methods for providing kink resistance by controlling stent stiffness are also disclosed. A stent having regions of different metallurgical properties is also disclosed, as are methods for creating such a stent.

    摘要翻译： 一种模块化细长支架，其具有两个模块化部件装配在一起的重叠区域，当所述支架处于组装构型时，所述重叠区域与所述支架的另一更柔性区域相比是相对刚性的，所述支架还包括模具区域， 刚度基本上等于重叠区域的刚度，以提供扭结阻力。 具有这种模拟区域或其他刚性区域和柔性区域的支架可以在刚性区域和柔性区域之间具有过渡区域，例如连接到支架的桥接材料，也提供扭结阻力。 支架可以具有相对刚性的区域和相对柔性的区域，其定位成当部署在体腔内时将柔性区域与体腔的弯曲区域对准。 可以通过将材料附接到支架，改变支架部件的横截面面积，改变其冶金特性和/或通过改变支架结构来控制刚性，柔性和过渡区域的刚度。 还公开了通过控制支架刚度提供扭结阻力的方法。 还公开了具有不同冶金特性的区域的支架，以及用于产生这种支架的方法。

    Dilatation catheter with varied stiffness
    4.
    发明授权
    Dilatation catheter with varied stiffness 失效
    扩张导管具有不同的刚度

    公开(公告)号：US6030405A

    公开(公告)日：2000-02-29

    申请号：US104949

    申请日：1998-06-25

    申请人： David J. Zarbatany ,  Rafael Pintor ,  Maurice Verbeek

    发明人： David J. Zarbatany ,  Rafael Pintor ,  Maurice Verbeek

    IPC分类号： A61M25/00 ,  A61M29/02 ,  A61M29/00

    CPC分类号： A61M25/0054 ,  A61M2025/0063 ,  A61M2025/0098 ,  A61M25/104

    摘要： A dilation catheter having a balloon inflation shaft with an inflation lumen into which a stiffening wire extends and a guidewire shaft having a guide wire lumen adjacent to the balloon. The stiffening wire includes at least two stepped diameter reductions along its length to vary stiffness from a stiff proximal end providing improved pushability to a less stiff distal end providing improved trackability. A manifold at the inflation shaft proximal end includes a handle for adjusting the distance the stiffening wire extends into the inflation lumen to allow stiffness to be optimized. The handle includes a tubular flange frictionally engaging the manifold to prevent inadvertent handle movement. The balloon inflation shaft and guidewire shafts are bonded together in a manner producing an assembly having a circular cross section for improved connection to a circular balloon and improved catheter performance.

    摘要翻译： 一种扩张导管，其具有球囊充气轴，所述球囊充气轴具有充气腔，加强线延伸到所述膨胀腔内，导丝轴具有与球囊相邻的导丝腔。 加强丝线沿其长度包括至少两个阶梯直径的减小，以从刚性近端改变刚度，从而提供对较不刚性的远端提供改善的推进性，从而提供改善的跟踪性。 在充气轴近端处的歧管包括用于调节加强丝延伸到充气腔中的距离的手柄，以允许优化刚度。 手柄包括与歧管摩擦接合的管状凸缘，以防止无意的手柄移动。 球囊充气轴和导丝轴以一种产生具有圆形横截面的组件的方式结合在一起，以改善与圆形气囊的连接并改善导管性能。

    Dilatation catheter with varied stiffness
    7.
    发明授权
    Dilatation catheter with varied stiffness 失效

    公开(公告)号：US5810867A

    公开(公告)日：1998-09-22

    申请号：US847897

    申请日：1997-04-28

    申请人： David J. Zarbatany ,  Rafael Pintor ,  Maurice T. Verbeek

    发明人： David J. Zarbatany ,  Rafael Pintor ,  Maurice T. Verbeek

    IPC分类号： A61M25/00 ,  A61M29/02 ,  A61M29/00

    CPC分类号： A61M25/0054 ,  A61M2025/0063 ,  A61M2025/0098 ,  A61M25/104

    摘要： A dilation catheter having a balloon inflation shaft with an inflation lumen into which a stiffening wire extends and a guidewire shaft having a guide wire lumen adjacent to the balloon. The stiffening wire includes at least two stepped diameter reductions along its length to vary stiffness from a stiff proximal end providing improved pushability to a less stiff distal end providing improved trackability. A manifold at the inflation shaft proximal end includes a handle for adjusting the distance the stiffening wire extends into the inflation lumen to allow stiffness to be optimized. The handle includes a tubular flange frictionally engaging the manifold to prevent inadvertent handle movement. The balloon inflation shaft and guidewire shafts are bonded together in a manner producing an assembly having a circular cross section for improved connection to a circular balloon and improved catheter performance.