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1.发明申请Reconstitution system for mixing the contents of a vial containing a first substance with a second substance stored in a cartridge 有权用于将容纳第一物质的小瓶的内容物与存储在筒中的第二物质混合的重构系统公开(公告)号：US20080172001A1
公开(公告)日：2008-07-17
申请号：US11974737
申请日：2007-10-16
IPC分类号： A61M5/00
CPC分类号： A61J1/2089 , A61J1/062 , A61J1/201 , A61J1/2013 , A61J1/2051 , A61J1/2055 , A61J1/2065
摘要： A transfer assembly for transfering a fluid to a vial, admixing the same and then returning the fluid to a cartridge, the transfer assembly having a vial gripper located at a first end and a cartridge holder at the second end of an elongated outer housing, a fluid passageway extending between the vial gripper and the cartridge holder with piercing elements being located at respective ends of the fluid passageway. In a preferred embodiment, an adaptor is mounted on the end of the outer housing where the cartridge holder is situated. The adaptor may move from a retracted to an extended position wherein it will surround the needle.
摘要翻译： 一种转移组件，用于将流体转移到小瓶中，将其混合，然后将流体返回到药筒，转移组件具有位于第一端的小瓶夹持器和位于细长外壳体的第二端处的药筒保持器， 流体通道在小瓶夹持器和药筒保持器之间延伸，穿刺元件位于流体通道的相应端部处。 在优选实施例中，适配器安装在外壳的其中盒保持器所在的端部。 适配器可以从缩回移动到延伸位置，其中它将围绕针。
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公开(公告)号：US20110068124A1
公开(公告)日：2011-03-24
申请号：US12737013
申请日：2009-06-10
IPC分类号： B67D7/06
CPC分类号： B01F15/0201 , A61M5/2448 , A61M2005/3152 , B01F13/002 , B01F13/0023 , B01F15/0087 , B01F15/0237
摘要： A device for mixing a substance comprised of two constituents contained in a cartridge (12) and having a cartridge holder (32) thereabout, the device comprising a plunger rod (46) for pushing a closure member (20) to permit the transfer of a diluent in a second chamber (28) through a by-pass channel (24) to mix with a constituent in a first chamber (26), the plunger rod (48) being driven by means of a rack (48) and a pinion gear (50) arrangement to prevent overly rapid movement of the plunger rod (46).
摘要翻译： 一种用于混合包含在盒（12）中的两个组分并且在其周围具有盒保持器（32）的物质的装置，该装置包括用于推动封闭构件（20）以允许传送一个 稀释剂通过旁通通道（24）在第二腔室（28）中与第一腔室（26）中的组分混合，柱塞杆（48）通过齿条（48）和小齿轮 （50）布置以防止柱塞杆（46）的过度快速移动。
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公开(公告)号：US20100042071A1
公开(公告)日：2010-02-18
申请号：US12462696
申请日：2009-08-06
IPC分类号： A61M5/32
CPC分类号： A61M5/385 , A61J1/201 , A61J1/2055 , A61J1/2096
摘要： A method for transferring and mixing a pharmaceutical mixture utilizing a by-pass cartridge and a syringe. After mixing the dry component and the diluent in the by-pass cartridge, the mixture can be passed to a syringe which includes a syringe plunger having a fluid passageway therein with a hydrophobic membrane covering the passageway. The mixture can be transferred back and forth between the by-pass cartridge and the syringe through a small bore to achieve mixing, particularly in the case of microspheres held in suspension.
摘要翻译： 一种利用旁路药筒和注射器转运和混合药物混合物的方法。 在旁路盒中混合干燥组分和稀释剂之后，可以将混合物送入注射器，该注射器包括其中具有流体通道的注射器柱塞，其中覆盖通道的疏水膜。 混合物可以通过小孔在旁路筒和注射器之间来回传递以实现混合，特别是在保持悬浮的微球的情况下。
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公开(公告)号：US08523807B2
公开(公告)日：2013-09-03
申请号：US12009783
申请日：2008-01-22
IPC分类号： A61M37/00
CPC分类号： A61M5/385 , A61J1/201 , A61J1/2055 , A61J1/2096
摘要： A transfer and mixing device which utilizes a by-pass cartridge and a syringe. After mixing the dry component and the diluent in the by-pass cartridge, the mixture can be passed to a syringe which includes a syringe plunger having a fluid passageway therein with a hydrophobic membrane covering the passageway. The mixture can be transferred back and forth between the by-pass cartridge and the syringe through a small bore to achieve mixing, particularly in the case of microspheres held in suspension.
摘要翻译： 一种利用旁路药筒和注射器的转运和混合装置。 在旁路盒中混合干燥组分和稀释剂之后，可以将混合物送入注射器，该注射器包括其中具有流体通道的注射器柱塞，其中覆盖通道的疏水膜。 混合物可以通过小孔在旁路筒和注射器之间来回传递以实现混合，特别是在保持悬浮的微球的情况下。
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公开(公告)号：US20120330280A1
公开(公告)日：2012-12-27
申请号：US13507273
申请日：2012-06-18
IPC分类号： A61M5/31
CPC分类号： A61M5/385 , A61J1/201 , A61J1/2055 , A61J1/2096
摘要： A method for transferring and mixing a pharmaceutical mixture utilizing a by-pass cartridge and a syringe. After mixing the dry component and the diluent in the by-pass cartridge, the mixture can be passed to a syringe which includes a syringe plunger having a fluid passageway therein with a hydrophobic membrane covering the passageway. The mixture can be transferred back and forth between the by-pass cartridge and the syringe through a small bore to achieve mixing, particularly in the case of microspheres held in suspension.
摘要翻译： 一种利用旁路药筒和注射器转运和混合药物混合物的方法。 在旁路盒中混合干燥组分和稀释剂之后，可以将混合物送入注射器，该注射器包括其中具有流体通道的注射器柱塞，其中覆盖通道的疏水膜。 混合物可以通过小孔在旁路筒和注射器之间来回传递以实现混合，特别是在保持悬浮的微球的情况下。
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公开(公告)号：US08123084B2
公开(公告)日：2012-02-28
申请号：US12737013
申请日：2009-06-10
IPC分类号： B67D7/60
CPC分类号： B01F15/0201 , A61M5/2448 , A61M2005/3152 , B01F13/002 , B01F13/0023 , B01F15/0087 , B01F15/0237
摘要： A device for mixing a substance comprised of two constituents contained in a cartridge (12) and having a cartridge holder (32) thereabout, the device comprising a plunger rod (46) for pushing a closure member (20) to permit the transfer of a diluent in a second chamber (28) through a by-pass channel (24) to mix with a constituent in a first chamber (26), the plunger rod (48) being driven by means of a rack (48) and a pinion gear (50) arrangement to prevent overly rapid movement of the plunger rod (46).
摘要翻译： 一种用于混合包含在盒（12）中的两个组分并且在其周围具有盒保持器（32）的物质的装置，该装置包括用于推动封闭构件（20）以允许传送一个 稀释剂通过旁通通道（24）在第二腔室（28）中与第一腔室（26）中的组分混合，柱塞杆（48）通过齿条（48）和小齿轮 （50）布置以防止柱塞杆（46）的过度快速移动。
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公开(公告)号：US20080188828A1
公开(公告)日：2008-08-07
申请号：US12009783
申请日：2008-01-22
CPC分类号： A61M5/385 , A61J1/201 , A61J1/2055 , A61J1/2096
摘要： A transfer and mixing device which utilizes a by-pass cartridge and a syringe. After mixing the dry component and the diluent in the by-pass cartridge, the mixture can be passed to a syringe which includes a syringe plunger having a fluid passageway therein with a hydrophobic membrane covering the passageway. The mixture can be transferred back and forth between the by-pass cartridge and the syringe through a small bore to achieve mixing, particularly in the case of microspheres held in suspension.
摘要翻译： 一种利用旁路药筒和注射器的转运和混合装置。 在旁路盒中混合干燥组分和稀释剂之后，可以将混合物送入注射器，该注射器包括其中具有流体通道的注射器柱塞，其中覆盖通道的疏水膜。 混合物可以通过小孔在旁路筒和注射器之间来回传递以实现混合，特别是在保持悬浮的微球的情况下。
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公开(公告)号：US08998880B2
公开(公告)日：2015-04-07
申请号：US13507273
申请日：2012-06-18
CPC分类号： A61M5/385 , A61J1/201 , A61J1/2055 , A61J1/2096
摘要： A method for transferring and mixing a pharmaceutical mixture utilizing a by-pass cartridge and a syringe. After mixing the dry component and the diluent in the by-pass cartridge, the mixture can be passed to a syringe which includes a syringe plunger having a fluid passageway therein with a hydrophobic membrane covering the passageway. The mixture can be transferred back and forth between the by-pass cartridge and the syringe through a small bore to achieve mixing, particularly in the case of microspheres held in suspension.
摘要翻译： 一种利用旁路药筒和注射器转运和混合药物混合物的方法。 在旁路盒中混合干燥组分和稀释剂之后，可以将混合物送入注射器，该注射器包括其中具有流体通道的注射器柱塞，其中覆盖通道的疏水膜。 混合物可以通过小孔在旁路筒和注射器之间来回传递以实现混合，特别是在保持悬浮的微球的情况下。
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9.发明授权Reconstitution system for mixing the contents of a vial containing a first substance with a second substance stored in a cartridge 有权用于将容纳第一物质的小瓶的内容物与存储在筒中的第二物质混合的重构系统公开(公告)号：US08100154B2
公开(公告)日：2012-01-24
申请号：US11974737
申请日：2007-10-16
IPC分类号： B65B1/04
CPC分类号： A61J1/2089 , A61J1/062 , A61J1/201 , A61J1/2013 , A61J1/2051 , A61J1/2055 , A61J1/2065
摘要： A transfer assembly for transfering a fluid to a vial, admixing the same and then returning the fluid to a cartridge, the transfer assembly having a vial gripper located at a first end and a cartridge holder at the second end of an elongated outer housing, a fluid passageway extending between the vial gripper and the cartridge holder with piercing elements being located at respective ends of the fluid passageway. In a preferred embodiment, an adaptor is mounted on the end of the outer housing where the cartridge holder is situated. The adaptor may move from a retracted to an extended position wherein it will surround the needle.
摘要翻译： 一种转移组件，用于将流体转移到小瓶中，将其混合，然后将流体返回到药筒，转移组件具有位于第一端的小瓶夹持器和位于细长外壳体的第二端处的药筒保持器， 流体通道在小瓶夹持器和药筒保持器之间延伸，穿刺元件位于流体通道的相应端部处。 在优选实施例中，适配器安装在外壳的其中盒保持器所在的端部。 适配器可以从缩回移动到延伸位置，其中它将围绕针。
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公开(公告)号：US20090308895A1
公开(公告)日：2009-12-17
申请号：US12157866
申请日：2008-06-13
CPC分类号： B01F15/0201 , A61M5/2448 , A61M2005/3152 , B01F13/002 , B01F13/0023 , B01F15/0087 , B01F15/0237
摘要： A device for mixing a substance comprised of two constituents contained in a cartridge and having a cartridge holder thereabout, the device comprising a plunger rod for pushing the closure member to permit the transfer of a diluent in a first chamber through a by-pass channel to mix with a constituent in a first chamber, the plunger rod being driven by means of a rack and a pinion gear arrangement to prevent overly rapid movement of the plunger rod.
摘要翻译： 一种用于混合包含在盒中的两个组分并且在其周围具有盒保持器的物质的装置，该装置包括用于推动封闭构件的柱塞杆，以允许通过旁通通道将第一室中的稀释剂转移到 与第一室中的组分混合，柱塞杆通过齿条和小齿轮装置驱动，以防止柱塞杆的过度快速运动。
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