利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

98 条记录 (耗时 0.049 秒)

    Distributed charge inflator system
    2.
    发明授权
    Distributed charge inflator system 失效
    分布充电充气机系统

    公开(公告)号：US07162958B2

    公开(公告)日：2007-01-16

    申请号：US10224435

    申请日：2002-08-21

    申请人： David Shilliday ,  Gregory J. Scaven ,  Kevin Fitzgerald

    发明人： David Shilliday ,  Gregory J. Scaven ,  Kevin Fitzgerald

    IPC分类号： C06D5/00

    CPC分类号： B60R21/272 ,  B60R21/23138 ,  B60R21/232 ,  B60R21/2644 ,  B60R21/2646 ,  B60R2021/0018 ,  B60R2021/2648 ,  C06D5/06

    摘要： An inflator includes a distributed charge to be distributed within an inflatable component of an inflatable system and a housing. The housing includes a combustion chamber and a gas storage chamber. The combustion chamber includes an initiator and a gas propellant. The gas storage chamber includes an inert gas at a high pressure. The housing also includes a gas nozzle. The distributed charge is connected to the housing through the gas nozzle. The distributed charge may be mechanically joined to the housing by a ferrule. Upon receiving an electrical signal from a crash sensor or other activator, the initiator ignites the gas propellant in the combustion chamber. The hot gas and hot particles from the burning gas propellant and the initiator flow into the gas storage chamber and heat the compressed inert gas in the gas storage chamber. The heated, compressed gas in the gas storage chamber flows through the gas nozzle and ignites the distributed charge. Combustion of the distributed charge generates a high volume of gas and inflates an inflatable component of an inflatable system.

    摘要翻译： 充气机包括分布在充气系统和壳体的可充气部件内的电荷。 壳体包括燃烧室和气体储存室。 燃烧室包括引发剂和气体推进剂。 气体储存室包括高压惰性气体。 壳体还包括气体喷嘴。 分配的电荷通过气体喷嘴连接到壳体。 分配的电荷可以通过套圈机械地接合到壳体。 当从碰撞传感器或其他激活器接收到电信号时，起动器点燃燃烧室中的气体推进剂。 来自燃烧气体推进剂和引发剂的热气体和热颗粒流入气体储存室，并加热储气室中的压缩惰性气体。 气体储存室中的加热的压缩气体流过气体喷嘴并点燃分布的电荷。 分配的电荷的燃烧产生大量的气体并且使充气系统的可充气部件膨胀。

    Membrane-translocating peptides
    8.
    发明授权
    Membrane-translocating peptides 有权
    膜易位肽

    公开(公告)号：US08557744B2

    公开(公告)日：2013-10-15

    申请号：US11996496

    申请日：2006-07-24

    申请人： David Coomber ,  Kevin Fitzgerald ,  Duncan McGregor ,  Chris Ullman ,  Tomas Leanderson

    发明人： David Coomber ,  Kevin Fitzgerald ,  Duncan McGregor ,  Chris Ullman ,  Tomas Leanderson

    IPC分类号： C40B30/04 ,  C12Q1/70

    CPC分类号： C12N15/1075

    摘要： A method is selects membrane-translocating peptides (MTPs) from a peptide display library that are capable of crossing or penetrating a lipid membrane. A plurality of nucleic acid constructs that encode displayed peptides are expressed, resulting in the formation of a plurality of nucleic acid-peptide complexes, each complex comprising at least one displayed peptide associated with the corresponding nucleic acid construct encoding the displayed peptide; the complexes are exposed to a population of membrane-encapsulated compartments, allowing a translocating reaction to occur; complexes that remain unassociated with the membrane are removed; optionally complexes that are associated with the membrane are removed; and internalized nucleic acid-peptide complexes are recovered. The membrane-encapsulated compartments may be artificial vesicles such as liposomes, or populations of one or more cell types.

    摘要翻译： 一种方法是从能够穿透或穿透脂质膜的肽展示文库中选择膜 - 位移肽（MTP）。 表达编码显示的肽的多个核酸构建体，导致形成多个核酸 - 肽复合物，每个复合物包含与编码所显示肽的相应核酸构建体相关联的至少一个显示的肽; 复合物暴露于膜包封的隔室群，允许发生易位反应; 与膜保持不相关的复合物被去除; 去除与膜相关的任选复合物; 并回收内化的核酸 - 肽复合物。 膜包封的隔室可以是人造囊泡，例如脂质体或一种或多种细胞类型的群体。