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公开(公告)号：US20090138000A1
公开(公告)日：2009-05-28
申请号：US12321818
申请日：2009-01-26
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/4216 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262
摘要： A cryoablation system including a cannula having a proximal end, a distal end, and a longitudinal axis, an expandable balloon extending from the distal end of the cannula and fluidly connected to a source of heat transfer fluid by at least one fluid path, a pump for circulating the heat transfer fluid into and out of the balloon, a probe handle coupled to the proximal end of the cannula and in fluidic communication with the balloon through the cannula, and a heat exchanger for varying the temperature of the heat transfer fluid, wherein the heat exchanger is fluidly connected to a secondary refrigerant source. The heat exchanger may be positioned within the probe handle, within the cannula, or at least partially within the balloon. The heat transfer fluid of this cryoablation system preferably has a freezing point lower than about −110° C. and a boiling point greater than about 50° C.
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公开(公告)号：US07500973B2
公开(公告)日：2009-03-10
申请号：US11020791
申请日：2004-12-22
IPC分类号： A61B18/18
CPC分类号： A61B18/02 , A61B2017/4216 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262
摘要： A cryoablation system including a cannula having a proximal end, a distal end, and a longitudinal axis, an expandable balloon extending from the distal end of the cannula and fluidly connected to a source of heat transfer fluid by at least one fluid path, a pump for circulating the heat transfer fluid into and out of the balloon, a probe handle coupled to the proximal end of the cannula and in fluidic communication with the balloon through the cannula, and a heat exchanger for varying the temperature of the heat transfer fluid, wherein the heat exchanger is fluidly connected to a secondary refrigerant source. The heat exchanger may be positioned within the probe handle, within the cannula, or at least partially within the balloon. The heat transfer fluid of this cryoablation system preferably has a freezing point lower than about −110° C. and a boiling point greater than about 50° C.
摘要翻译： 一种冷冻消融系统，包括具有近端，远端和纵向轴线的插管，从套管的远端延伸并且通过至少一个流体路径流体连接到传热流体源的可膨胀气囊，泵 用于使所述传热流体循环到所述球囊中;探针手柄，其耦合到所述套管的近端并通过所述套管与所述球囊流体连通;以及热交换器，用于改变所述传热流体的温度，其中 热交换器流体地连接到二次制冷剂源。 热交换器可以位于探针手柄内，套管内，或者至少部分地位于气囊内。 该冷冻消融系统的传热流体优选具有低于约-110℃的凝固点和大于约50℃的沸点。
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公开(公告)号：US07381208B2
公开(公告)日：2008-06-03
申请号：US11020792
申请日：2004-12-22
IPC分类号： A61B18/18
CPC分类号： A61B18/02 , A61B2017/4216 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262
摘要： A cryoablation system for performing endometrial ablation comprising an elongated tubular cannula having a proximal end, a distal end, and a longitudinal axis, an expandable balloon extending from the distal end of the cannula and fluidly connected to a source of heat transfer fluid by at least one fluid path, a pump for circulating the heat transfer fluid into and out of the balloon, a probe handle coupled to the proximal end of the cannula and in fluidic communication with the balloon through the cannula, and a heat exchanger for varying the temperature of the heat transfer fluid, wherein the heat exchanger is fluidly connected to a secondary refrigerant source, and wherein the heat exchanger comprises an outer tubular wall and a plurality of fins extending from the tubular wall toward the interior portion of the heat exchanger.
摘要翻译： 一种用于进行子宫内膜消融的冷冻消融系统，包括具有近端，远端和纵向轴线的细长管状插管，从套管的远端延伸并且至少流体连接到传热流体源的可膨胀气囊 一个流体路径，用于将传热流体循环到气囊中的泵;耦合到套管的近端并通过插管与气囊流体连通的探针手柄，以及用于改变温度的热交换器 所述传热流体，其中所述热交换器流体地连接到二次制冷剂源，并且其中所述热交换器包括外部管状壁和从所述管状壁朝向所述热交换器的内部延伸的多个翅片。
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公开(公告)号：US20080027420A1
公开(公告)日：2008-01-31
申请号：US11828095
申请日：2007-07-25
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B34/10 , A61B90/37 , A61B2017/00101
摘要： Improved imaging and monitoring systems for use with a closed loop cryosurgical system. As described herein, various systems can be used alone or in conjunction with one another to plan and/or monitor cryosurgical procedures in order to improve cryosurgical outcomes. These systems can include computer assisted planning systems, non-ultrasound based imaging systems and temperature monitoring systems utilized individually or in combination. Through the use of these systems, the precision by which cryosurgical procedures are performed are enhanced.
摘要翻译： 改进的成像和监测系统用于闭环冷冻手术系统。 如本文所述，各种系统可以单独使用或者彼此结合使用来规划和/或监测冷冻手术程序，以便改善冷冻手术的结果。 这些系统可以包括计算机辅助计划系统，基于非超声的成像系统和单独或组合使用的温度监测系统。 通过使用这些系统，提高了执行冷冻手术的精度。
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公开(公告)号：US20110112524A1
公开(公告)日：2011-05-12
申请号：US12927311
申请日：2010-11-10
CPC分类号： A61B18/1492 , A61B18/1206 , A61B18/1485 , A61B2018/00011 , A61B2018/00083 , A61B2018/0016 , A61B2018/00214 , A61B2018/00267 , A61B2018/00482 , A61B2018/00559 , A61B2018/00577 , A61B2018/00684 , A61B2018/00916 , A61B2018/1407 , A61B2018/1437 , A61B2018/144 , A61B2018/1465 , A61B2018/1467 , A61B2018/1475 , A61B2218/007 , A61M25/0136 , A61M25/0147
摘要： An ablation apparatus places electrodes at the perimeter of a cavity. In an embodiment, the alternating electric field is used to expose the cavity to enough energy to ablate the cavity. In an embodiment, two modes are used to expose different regions of the cavity to different amounts of power for so that the thermal effect is more uniform. In an embodiment, the electrodes have a relatively large surface area so as to avoid charring the cavity, but are shaped so as to fit within a body orifice. For example, the diameter of the sheathed housing the electrodes during penetration may be only 5.5 mm.
摘要翻译： 消融装置将电极放置在空腔的周边。 在一个实施例中，交变电场用于将空腔暴露于足够的能量以消融空腔。 在一个实施例中，使用两种模式来将空腔的不同区域暴露于不同的功率量，使得热效应更均匀。 在一个实施例中，电极具有相对较大的表面积，以避免烧焦空腔，但是成形为适合于主体孔。 例如，在穿透期间，护套电极的直径可以仅为5.5mm。
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公开(公告)号：US07806917B2
公开(公告)日：2010-10-05
申请号：US11736465
申请日：2007-04-17
申请人： Jia Hua Xiao
发明人： Jia Hua Xiao
IPC分类号： A61F2/06
CPC分类号： A61B17/0682 , A61B17/12118 , A61B2017/0649 , A61B2017/1205 , A61F2/07 , A61F2/848 , A61F2/89 , A61F2002/075 , A61F2002/8483 , A61F2230/0054
摘要： A stent graft fixation system and method including a stent graft for fastening to a fixation point in a body lumen, the stent graft including a stent; a graft material supported by the stent and having a fixation region; and a guide suture joined to the graft material in the fixation region. The guide suture has a length selected to extend from the fixation point to outside of the body lumen.
摘要翻译： 一种支架植入物固定系统和方法，包括用于紧固到体腔内的固定点的支架移植物，所述支架植入物包括支架; 由支架支撑并具有固定区域的移植材料; 以及与固定区域中的移植材料接合的引导缝合线。 引导缝合线具有从固定点延伸到体腔外部的长度。
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公开(公告)号：US20090270971A1
公开(公告)日：2009-10-29
申请号：US12109076
申请日：2008-04-24
申请人： Jia Hua Xiao , Trevor Greenan , Walter Bruszewski , David Gray , Mark L. Stiger , Morgan House , Matthew Rust
发明人： Jia Hua Xiao , Trevor Greenan , Walter Bruszewski , David Gray , Mark L. Stiger , Morgan House , Matthew Rust
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/848 , A61F2/89 , A61F2002/075 , A61F2002/8486 , A61F2220/0016 , A61F2220/005 , A61F2220/0075 , A61F2220/0091 , A61F2230/0013 , A61F2230/005
摘要： A tubular prosthesis comprises a tubular graft; and an undulating stent having a plurality of apexes, a first end defined at least in part by a first group of the apexes, and a second end defined at least in part by a second group of the apexes, the first group of apexes being pivotally attached to the tubular graft so as to form a plurality of circumferentially arranged hinges about which the stent can pivot so that the second group of apexes can move between a position where they are inside the tubular graft and a position where they are outside the tubular graft. In one embodiment a tubular prosthesis comprises a tubular graft having a first end margin, a second end margin and a central portion therebetween; and an undulating stent having a plurality of apexes, a first end defined at least in part by a first group of the apexes, and a second end defined at least in part by a second group of the apexes, the undulating stent being secured to the tubular graft in a manner such that it can be inverted to extend generally in the same direction as the tubular graft with one end thereof forming an end of said tubular prosthesis and pointing away from the central portion of the tubular graft.
摘要翻译： 管状假体包括管状移植物; 以及具有多个顶点的起伏支架，第一端部至少部分地由第一组顶点限定，第二端部至少部分地由第二组顶点限定，第一组顶点枢轴 附接到管状移植物以形成多个周向布置的铰链，支架可围绕该铰链枢转，使得第二组顶点可以在它们在管状移植物内部的位置和它们在管状移植物外部的位置之间移动 。 在一个实施例中，管状假体包括具有第一端部边缘，第二端部边缘和中间部分之间的管状移植物; 和具有多个顶点的起伏支架，第一端部至少部分地由第一组顶点限定，第二端部至少部分地由第二组顶点限定，波状支架固定到 管状移植物的方式使得其可以反向以与管状移植物相同的方向延伸，其一端形成所述管状假体的端部并且远离管状移植物的中心部分。
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公开(公告)号：US06960203B2
公开(公告)日：2005-11-01
申请号：US10183600
申请日：2002-06-26
申请人： Jia Hua Xiao , Carrie M. Brookner , Craig Hidalgo
发明人： Jia Hua Xiao , Carrie M. Brookner , Craig Hidalgo
CPC分类号： A61B18/04 , A61B18/08 , A61B2017/22051 , A61B2017/4216 , A61B2018/044
摘要： A medical device is provided and includes a thermal ablation catheter and a deployable cage assembly for use in thermal ablation therapy. The deployable cage assembly includes a plurality of arms, each of which has a pair of opposed ends attached to the thermal ablation catheter. Each of the arms is movable from a relaxed configuration to a deployed configuration. When relaxed, the arms are substantially proximate to the thermal ablation catheter. When deployed, the arms cooperate with each other to form an open structure which extends radially outward from the thermal ablation catheter. The thermal ablation device also includes a distensible bladder that serves as an endocervical seal.
摘要翻译： 提供了一种医疗设备，并且包括用于热消融治疗的热消融导管和可展开的保持架组件。 可部署的保持架组件包括多个臂，每个臂具有连接到热消融导管的一对相对端。 每个臂可以从轻松的配置移动到展开的配置。 当松弛时，臂基本上靠近热消融导管。 当展开时，臂彼此协作以形成从热消融导管径向向外延伸的开放结构。 热消融装置还包括用作子宫颈内密封的可扩张囊。
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公开(公告)号：US20080262596A1
公开(公告)日：2008-10-23
申请号：US11736465
申请日：2007-04-17
申请人： Jia Hua Xiao
发明人： Jia Hua Xiao
IPC分类号： A61F2/06
CPC分类号： A61B17/0682 , A61B17/12118 , A61B2017/0649 , A61B2017/1205 , A61F2/07 , A61F2/848 , A61F2/89 , A61F2002/075 , A61F2002/8483 , A61F2230/0054
摘要： A stent graft fixation system and method including a stent graft for fastening to a fixation point in a body lumen, the stent graft including a stent; a graft material supported by the stent and having a fixation region; and a guide suture joined to the graft material in the fixation region. The guide suture has a length selected to extend from the fixation point to outside of the body lumen.
摘要翻译： 一种支架植入物固定系统和方法，包括用于紧固到体腔内的固定点的支架移植物，所述支架植入物包括支架; 由支架支撑并具有固定区域的移植材料; 以及与固定区域中的移植材料接合的引导缝合线。 引导缝合线具有从固定点延伸到体腔外部的长度。
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10.发明授权公开(公告)号：US07115124B1
公开(公告)日：2006-10-03
申请号：US10973056
申请日：2004-10-25
申请人： Jia Hua Xiao
发明人： Jia Hua Xiao
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B2018/0016 , A61B2018/143
摘要： A device for tissue ablation comprises plural arrays of segmented needle electrodes, each of which contains a plurality of electrically conductive segments, a plurality of non-conductive joints, and a needle tip. Each of the electrically conductive segments is wired to a radio-frequency electrical power source and can be connected to and disconnected from the power source. After the needle electrodes of the device are penetrated into a target tissue to be ablated, the intended volume of ablation can be configured in three dimensions. Thus, the device allows physicians to effectively control ablation boundaries.
摘要翻译： 用于组织消融的装置包括多个分段针电极阵列，每个阵列的针电极包含多个导电段，多个非导电接头和针尖。 每个导电段被连接到射频电源，并且可以连接到电源并从电源断开。 在装置的针电极穿透到待烧伤的目标组织中之后，预期的消融体积可以被构造成三维。 因此，该装置允许医生有效地控制消融边界。
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