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公开(公告)号：US06746392B2
公开(公告)日：2004-06-08
申请号：US09885112
申请日：2001-06-20
申请人： Mark L. Stiger , Sam Ciamacco, Jr.
发明人： Mark L. Stiger , Sam Ciamacco, Jr.
IPC分类号： A61N500
CPC分类号： A61N5/1002 , A61N2005/1003
摘要： An over-the-wire catheter provides substantially shadow-free delivery of radiation to a body lumen by having a treatment region wherein a guidewire tube and a radiation source tube form a parallel double helix configuration. When a radiation source is inserted into the radiation source tube and a guidewire is present in the guidewire tube, no portion of the treatment site will be obscured from all radiation emitted by the radiation source because, within the treatment region, the guidewire and the radiation source are not in a conventional, axially parallel configuration. Optionally, a balloon may be mounted about or adjacent the treatment region of the catheter, the balloon providing centering and/or dilatation functions.
摘要翻译： 线上导管通过具有其中导丝管和辐射源管形成平行双螺旋结构的治疗区域向体腔提供基本无阴影的辐射输送。 当辐射源被插入辐射源管中并且导丝存在于导丝管中时，处理部位的任何部分将不会被辐射源发射的所有辐射遮蔽，因为在处理区域内，导丝和辐射 源不是常规的轴向平行构造。 任选地，气囊可以安装在导管的治疗区域周围或附近，气囊提供定中心和/或扩张功能。
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公开(公告)号：US09358370B2
公开(公告)日：2016-06-07
申请号：US13418092
申请日：2012-03-12
申请人： Mark L. Stiger , Richard L. Thomas
发明人： Mark L. Stiger , Richard L. Thomas
CPC分类号： A61M25/09 , A61L31/022 , A61L31/146 , A61L31/18 , A61M2025/09075 , A61M2025/09108 , A61M2025/09133 , A61M2025/09166 , C23F4/00
摘要： Embodiments hereof relate to a guidewire formed from an elongated shaft, at least a portion of the shaft having an outer layer, a plurality of channels formed through the outer layer, and an inner core. The outer layer is formed from a material non susceptible to erosion by an erosion agent and the inner core is formed from a radiopaque material susceptible to erosion by the erosion agent. When exposed to the erosion agent, core material adjacent to the channels is removed to form a pattern of integral radiopaque segments or markers with a plurality of voids therebetween. By controlling the location of channels and the rate of erosion of the core material, the pattern of integral radiopaque segments and voids allow for in situ measurement when viewed under fluoroscopy.
摘要翻译： 本发明的实施方案涉及由细长轴形成的导丝，所述轴的至少一部分具有外层，穿过外层形成的多个通道和内芯。 外层由不易受侵蚀剂侵蚀的材料形成，内芯由易受腐蚀剂腐蚀的不透射线材料形成。 当暴露于侵蚀剂时，除去与通道相邻的芯材料以形成其间具有多个空隙的整体不透射线段或标记的图案。 通过控制通道的位置和芯材的侵蚀速率，整体不透射线段和空隙的图案允许在荧光透视下观察时的原位测量。
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公开(公告)号：US06589274B2
公开(公告)日：2003-07-08
申请号：US09816795
申请日：2001-03-23
申请人： Mark L. Stiger , Michael A. Mohn , Mark Hoekwater , Lior Sobe
发明人： Mark L. Stiger , Michael A. Mohn , Mark Hoekwater , Lior Sobe
IPC分类号： A61F206
CPC分类号： A61F2/958 , A61F2002/9583
摘要： A stent delivery catheter includes an extendable shaft portion, a tubular balloon mounted thereon, a stent and a pair of elastic retaining caps. The balloon is mounted onto the catheter at a mounted length that is shorter than the formed length of the balloon to generate excess balloon material which is gathered into circumferential folds. The extendable portion of the catheter shaft elongates in response to tension applied by the balloon as the folds open during inflation. Elongation of the catheter shaft drives the retaining caps apart to uncover the ends of the stent.
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4.发明授权公开(公告)号：US06183505B2
公开(公告)日：2001-02-06
申请号：US09266113
申请日：1999-03-11
IPC分类号： A61F206
CPC分类号： A61F2/958 , A61F2002/9583
摘要： A stent delivery balloon catheter system includes a pair of retainers which are anchored to the catheter to hold the stent against the balloon until the stent is to be deployed. Each retainer is made of filaments which are woven together to form a braided tube shaped structure. Further, each retainer has one end which is anchored to the catheter while the free end of the retainer overlaps a respective end of the stent. Upon inflation of the balloon for deployment of the stent, the balloon also urges against each retainer. This causes the woven tube structure of the retainer to expand, and thereby shorten. As the retainers shorten, they also withdrawn from the stent, and thereby release the stent for deployment.
摘要翻译： 支架递送球囊导管系统包括一对保持器，其被锚定到导管以将支架保持在抵靠气囊上直到支架被展开。 每个保持器由长丝组成，其编织在一起以形成编织管状结构。 此外，每个保持器具有固定到导管的一端，而保持器的自由端与支架的相应端部重叠。 当用于展开支架的气囊膨胀时，气囊也推动每个保持器。 这使得保持器的编织管结构膨胀，从而缩短。 随着保持器缩短，它们也从支架中退出，从而释放用于展开的支架。
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公开(公告)号：US20100268315A1
公开(公告)日：2010-10-21
申请号：US12426020
申请日：2009-04-17
申请人： Brian Glynn , Mark L. Stiger
发明人： Brian Glynn , Mark L. Stiger
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61F2002/9505
摘要： A method of deploying a stent graft includes radially constraining proximal apexes of a proximal anchor stent ring of the stent-graft in a space between merlons of a castellated sleeve of a tip and a spindle having spindle pins, the proximal apexes extending around the spindle pins. A graft material of the stent-graft is radially constrained in a primary sheath, a proximal end of the graft material being attached to distal apexes of the proximal anchor stent ring. The proximal anchor stent ring further includes struts extending between the proximal apexes and the distal apexes. The primary sheath is retracted to allow the proximal end of the graft material and the distal apexes of the proximal anchor stent ring to pivot out beyond the confines of the sleeve to a large angle as the proximal end radially expands. The struts then extend through embrasures of the castellated sleeve. The tip is advanced to deploy the proximal apexes.
摘要翻译： 一种部署支架移植物的方法包括将支架移植物的近端锚固支架环的近侧顶点径向约束在尖端的雉皮套管的鲤状物和具有心轴销的心轴之间的空间中，近端顶点围绕心轴销延伸 。 支架移植物的移植材料径向地约束在初级护套中，移植材料的近端附接到近端锚固支架环的远端顶点。 近端锚固支架环还包括在近端顶点和远侧顶点之间延伸的支柱。 主护套被缩回以允许移植物材料的近端和近端锚固支架环的远端顶点在近端径向扩张时枢转超出套管的范围到大角度。 支柱然后延伸穿过城堡套筒的囊袋。 尖端前进以部署近端顶点。
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公开(公告)号：US06547813B2
公开(公告)日：2003-04-15
申请号：US09815615
申请日：2001-03-23
申请人： Mark L. Stiger , Michael A. Mohn
发明人： Mark L. Stiger , Michael A. Mohn
IPC分类号： A61F206
CPC分类号： A61F2/958 , A61F2002/9583
摘要： A stent delivery catheter and method for making the same includes a tubular balloon, an elastic sleeve, and a stent. The balloon is mounted around a catheter shaft, and the stent is crimped onto the balloon. The elastic sleeve is positioned between the balloon and the stent, the sleeve extending beyond the ends of the stent where the ends of the sleeve are fixed to the catheter shaft. Sleeve material is gathered and folded over the ends of the stent to retain the stent snugly against the balloon during delivery.
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公开(公告)号：US5938582A
公开(公告)日：1999-08-17
申请号：US938780
申请日：1997-09-26
CPC分类号： A61N5/1002 , A61M2025/1047 , A61M2025/1072 , A61M25/1002 , A61N2005/1003
摘要： An apparatus for centering a radiation delivery device at a selected location in a body vessel such as a coronary artery. An elongated catheter is insertable into the body vessel until the catheter head is in the desired position. The catheter has a guidewire lumen, inflation lumen and treatment lumen running lengthwise. The catheter head includes an expandable mechanism for engaging the vessel internal wall with the treatment lumen centered in the vessel. At least one channel is provided extending past the expandable mechanism so that a fluid, such as blood, can perfuse past the catheter head. A radiation delivery device, such as a wire having a radiation source at the distal end can be inserted into the treatment lumen to uniformly irradiate the vessel wall at the selected location.
摘要翻译： 一种用于将放射线输送装置定心在诸如冠状动脉的体容器中的选定位置的装置。 细长导管可插入体内容器，直到导管头处于所需位置。 导管具有导丝管腔，充气腔和处理腔纵向延伸。 导管头包括用于使容器内壁与容器中心的处理腔接合的可扩张机构。 提供延伸通过可扩张机构的至少一个通道，使得诸如血液的流体可以灌注通过导管头。 诸如在远端具有辐射源的线的辐射递送装置可以被插入到处理腔中以在选定位置均匀地照射血管壁。
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公开(公告)号：US20090270971A1
公开(公告)日：2009-10-29
申请号：US12109076
申请日：2008-04-24
申请人： Jia Hua Xiao , Trevor Greenan , Walter Bruszewski , David Gray , Mark L. Stiger , Morgan House , Matthew Rust
发明人： Jia Hua Xiao , Trevor Greenan , Walter Bruszewski , David Gray , Mark L. Stiger , Morgan House , Matthew Rust
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/848 , A61F2/89 , A61F2002/075 , A61F2002/8486 , A61F2220/0016 , A61F2220/005 , A61F2220/0075 , A61F2220/0091 , A61F2230/0013 , A61F2230/005
摘要： A tubular prosthesis comprises a tubular graft; and an undulating stent having a plurality of apexes, a first end defined at least in part by a first group of the apexes, and a second end defined at least in part by a second group of the apexes, the first group of apexes being pivotally attached to the tubular graft so as to form a plurality of circumferentially arranged hinges about which the stent can pivot so that the second group of apexes can move between a position where they are inside the tubular graft and a position where they are outside the tubular graft. In one embodiment a tubular prosthesis comprises a tubular graft having a first end margin, a second end margin and a central portion therebetween; and an undulating stent having a plurality of apexes, a first end defined at least in part by a first group of the apexes, and a second end defined at least in part by a second group of the apexes, the undulating stent being secured to the tubular graft in a manner such that it can be inverted to extend generally in the same direction as the tubular graft with one end thereof forming an end of said tubular prosthesis and pointing away from the central portion of the tubular graft.
摘要翻译： 管状假体包括管状移植物; 以及具有多个顶点的起伏支架，第一端部至少部分地由第一组顶点限定，第二端部至少部分地由第二组顶点限定，第一组顶点枢轴 附接到管状移植物以形成多个周向布置的铰链，支架可围绕该铰链枢转，使得第二组顶点可以在它们在管状移植物内部的位置和它们在管状移植物外部的位置之间移动 。 在一个实施例中，管状假体包括具有第一端部边缘，第二端部边缘和中间部分之间的管状移植物; 和具有多个顶点的起伏支架，第一端部至少部分地由第一组顶点限定，第二端部至少部分地由第二组顶点限定，波状支架固定到 管状移植物的方式使得其可以反向以与管状移植物相同的方向延伸，其一端形成所述管状假体的端部并且远离管状移植物的中心部分。
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公开(公告)号：US20080167637A1
公开(公告)日：2008-07-10
申请号：US11549379
申请日：2006-10-13
IPC分类号： A61M31/00
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12136 , A61B17/12186 , A61B17/12195 , A61L24/001 , A61L24/06
摘要： An irritant or polymer is dispensed to the inner surface area of an aneurysm to exert a contractile force on the inner surface area of the aneurysm, thereby shrinking the aneurysm. As a result, the artery wall at the aneurysm site is strengthened, the risk of rupture is decreased, and at least a partial cure for the expansion of the arterial wall at the aneurysm site is provided.
摘要翻译： 刺激物或聚合物被分配到动脉瘤的内表面区域以在动脉瘤的内表面区域施加收缩力，从而使动脉瘤收缩。 结果，动脉瘤部位的动脉壁被加强，破裂的风险降低，并且提供至少部分治愈动脉瘤部位的动脉壁的膨胀。
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10.发明授权Intraluminal therapy catheter with inflatable helical member and methods of use 失效管腔内治疗导管与充气螺旋成员及使用方法公开(公告)号：US06679860B2
公开(公告)日：2004-01-20
申请号：US09885072
申请日：2001-06-19
申请人： Mark L. Stiger
发明人： Mark L. Stiger
IPC分类号： A61M2900
CPC分类号： A61M25/104 , A61M25/1002 , A61M25/1011 , A61M2025/1047
摘要： The invention is an intraluminal therapy catheter having a least two treatment members disposed near the distal end of the catheter, the members being independently inflatable to perform angioplasty and/or fluid-sourced brachytherapy. A first treatment member is helically mounted about the shaft of the catheter, and forms a helical perfusion channel when inflated into contact with the vessel being treated. In a first embodiment of the invention, the second treatment member is also helically mounted about the catheter shaft and capable of forming a helical perfusion channel when inflated into contact with the vessel. The first and second treatment members are intertwined to form a double helix configuration wherein each member is capable of being inflated to generally fill the helical perfusion channel created by simultaneous inflation of the other member. In a second embodiment of the invention, the second treatment member is a tubular balloon mounted generally coaxially about the catheter shaft, adjacent to the first treatment member.
摘要翻译： 本发明是一种管腔内治疗导管，其具有设置在导管远端附近的至少两个治疗部件，该部件独立地可充气以进行血管成形术和/或流体来源的近距离放射治疗。 第一处理构件围绕导管的轴线螺旋地安装，并且当膨胀与待处理的血管接触时，形成螺旋灌注通道。 在本发明的第一实施例中，第二处理构件也围绕导管轴螺旋安装，并且当膨胀成与容器接触时能够形成螺旋灌注通道。 第一和第二处理构件相互缠绕以形成双螺旋构造，其中每个构件能够被充气以通常填充通过另一构件的同时充气而产生的螺旋灌注通道。 在本发明的第二实施例中，第二处理构件是与导管轴大致同轴地安装的管状球囊，与第一处理构件相邻。
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