-
公开(公告)号：US20160030557A1
公开(公告)日：2016-02-04
申请号：US14775087
申请日：2014-03-13
申请人： David WEINER , Matthew MORROW , Jian YAN , Bernadette FERRARO , David HOKEY
发明人： David Weiner , Jian Yan , Matthew Morrow , Bernadette Ferraro , David Hokey
CPC分类号： A61K39/39 , A61K9/0009 , A61K39/015 , A61K39/12 , A61K2039/53 , A61K2039/54 , A61K2039/55527 , C07K14/54 , C12N7/00 , C12N15/03 , C12N2710/20033 , C12N2710/20034 , C12P21/02 , Y02A50/412
摘要： Disclosed herein is a vaccine comprising an antigen and IL-23. Also disclosed herein are methods for increasing an immune response in a subject. The methods may comprise administering the vaccine to the subject in need thereof.
摘要翻译： 本文公开了包含抗原和IL-23的疫苗。 本文还公开了增加受试者的免疫应答的方法。 所述方法可以包括向有需要的受试者施用疫苗。
-
公开(公告)号：US09669091B2
公开(公告)日：2017-06-06
申请号：US14775087
申请日：2014-03-13
申请人： David B. Weiner , Jian Yan , Matthew Morrow , Bernadette Ferraro , David Hokey
发明人： David B. Weiner , Jian Yan , Matthew Morrow , Bernadette Ferraro , David Hokey
IPC分类号： C12P21/02 , C12N15/03 , A61K39/39 , C07K14/54 , A61K9/00 , A61K39/015 , A61K39/12 , C12N7/00 , C12P21/00 , C12N15/09 , C12N15/10 , A61K39/00
CPC分类号： A61K39/39 , A61K9/0009 , A61K39/015 , A61K39/12 , A61K2039/53 , A61K2039/54 , A61K2039/55527 , C07K14/54 , C12N7/00 , C12N15/03 , C12N2710/20033 , C12N2710/20034 , C12P21/02 , Y02A50/412
摘要： Disclosed herein is a vaccine comprising an antigen and IL-23. Also disclosed herein are methods for increasing an immune response in a subject. The methods may comprise administering the vaccine to the subject in need thereof.
-
公开(公告)号：US20160022806A1
公开(公告)日：2016-01-28
申请号：US14774241
申请日：2014-03-12
申请人： David Weiner , Jian Yan , Matthew Morrow
发明人： David B. Weiner , Jian Yan , Matthew Morrow
IPC分类号： A61K39/145 , C12N7/00 , C07K14/005
CPC分类号： A61K39/145 , A61K39/12 , A61K2039/53 , A61K2039/70 , C07K14/005 , C07K2319/02 , C07K2319/42 , C12N7/00 , C12N2760/16022 , C12N2760/16034 , C12N2760/16041 , C12N2760/16071 , C12N2760/16122 , C12N2760/16134 , C12N2760/16222 , C12N2760/16234 , C12N2800/22
摘要： Provided herein are nucleic acid sequences that encode novel consensus amino acid sequences of HA hemagglutinin and/or influenza B hemagglutinin, as well as genetic constructs/vectors and vaccines expressing the sequences. Also provided herein are methods for generating an immune response against one or more influenza A serotypes and/or influenza B serotypes, or combinations thereof, using the vaccines that are provided.
-
公开(公告)号：US10022434B2
公开(公告)日：2018-07-17
申请号：US14774241
申请日：2014-03-12
申请人： David B. Weiner , Jian Yan , Matthew Morrow
发明人： David B. Weiner , Jian Yan , Matthew Morrow
IPC分类号： A61K39/145 , A61K39/12 , C07K14/005 , C12N7/00 , A61K39/00
摘要： Provided herein are nucleic acid sequences that encode novel consensus amino acid sequences of HA hemagglutinin and/or influenza B hemagglutinin, as well as genetic constructs/vectors and vaccines expressing the sequences. Also provided herein are methods for generating an immune response against one or more influenza A serotypes and/or influenza B serotypes, or combinations thereof, using the vaccines that are provided.
-
公开(公告)号：US20160038584A1
公开(公告)日：2016-02-11
申请号：US14774256
申请日：2014-03-12
申请人： David WEINER , Jian YAN , INOVIO PHARMACEUTICALS, INC. , The Trustees of the University of Pennsylvania
发明人： David B. Weiner , Jian Yan , Matthew Morrow
IPC分类号： A61K39/145 , C12N7/00 , C07K14/005
CPC分类号： A61K39/145 , A61K39/12 , A61K2039/53 , A61K2039/70 , C07K14/005 , C07K2319/02 , C07K2319/42 , C12N7/00 , C12N2760/16022 , C12N2760/16034 , C12N2760/16041 , C12N2760/16071 , C12N2760/16122 , C12N2760/16134 , C12N2760/16222 , C12N2760/16234 , C12N2800/22
摘要： Provided herein are nucleic acid sequences that encode novel consensus amino acid sequences of HA hemagglutinin and/or influenza B hemagglutinin, as well as genetic constructs/vectors and vaccines expressing the sequences. Also provided herein are methods for generating an immune response against one or more influenza A serotypes and/or influenza B serotypes, or combinations thereof, using the vaccines that are provided.
摘要翻译： 本文提供了编码HA血凝素和/或乙型血凝素的新共识氨基酸序列以及表达序列的遗传构建体/载体和疫苗的核酸序列。 本文还提供了使用提供的疫苗产生针对一种或多种甲型流感血清型和/或流感乙型血清型或其组合的免疫应答的方法。
-
-
-
-
搜索结果
5 条记录 (耗时 0.027 秒)
