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公开(公告)号:US20070104651A1
公开(公告)日:2007-05-10
申请号:US10522527
申请日:2004-11-17
申请人: David Wright , Anthony Harman , Nikki Robinson , Garry Hodges , Adil Kadar , Geoffrey Moggridge , Hugh Van Liew
发明人: David Wright , Anthony Harman , Nikki Robinson , Garry Hodges , Adil Kadar , Geoffrey Moggridge , Hugh Van Liew
IPC分类号: A61K9/12
CPC分类号: B65B3/003 , A61B17/00008 , A61B17/00491 , A61B17/12022 , A61B17/12109 , A61B17/12186 , A61B2017/00495 , A61K9/0019 , A61K9/08 , A61K9/122 , A61K9/124 , A61K31/08 , A61K47/02 , A61K47/10 , A61K47/20 , A61K47/32 , A61M5/178 , A61M5/19 , A61M16/00 , A61M2202/00 , A61M2210/086 , A61M2210/12 , B01F3/04446 , B01F5/0685 , B01F5/0693 , B01F13/0023 , B65B31/00 , Y10S514/945
摘要: A therapeutic foam for the treatment of, inter alia, varicose veins comprises a sclerosing solution foamed with a physiological gas such as carbon dioxide, oxygen or a mixture thereof. The foam has a nitrogen content of less than 0.8%. It may be generated using a pressurised canister system incorporating a fine mesh of micron dimensions through which the gas and sclerosing liquid are passed to make the foam. Alternatively, the foam may be generated by passing gas and solution between two syringes through a fine mesh. Techniques are described for minimising the amount of nitrogen in a canister or syringe based product. A technique for generating and delivering foam simultaneously using a syringe based device is also disclosed.
摘要翻译: 用于治疗静脉曲张的治疗性泡沫包括用诸如二氧化碳,氧气或其混合物的生理气体发泡的硬化溶液。 泡沫的氮含量小于0.8%。 它可以使用包含微米尺寸的精细网格的加压罐系统来产生,气体和硬化液通过该微孔尺寸通过以制造泡沫。 或者,泡沫可以通过气体和溶液在两个注射器之间通过细网而产生。 描述了用于最小化基于罐或注射器的产品中氮的量的技术。 还公开了一种使用基于注射器的装置同时产生和递送泡沫的技术。
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公开(公告)号:US20070003488A1
公开(公告)日:2007-01-04
申请号:US10522528
申请日:2004-11-17
申请人: David Wright , Anthony Harman , Nikki Robinson , Garry Hodges , Adil Kadar , Geoffrey Moggridge , Hugh Van Liew
发明人: David Wright , Anthony Harman , Nikki Robinson , Garry Hodges , Adil Kadar , Geoffrey Moggridge , Hugh Van Liew
IPC分类号: A61K9/00
CPC分类号: B65B3/003 , A61B17/00008 , A61B17/00491 , A61B17/12022 , A61B17/12109 , A61B17/12186 , A61B2017/00495 , A61K9/0019 , A61K9/08 , A61K9/122 , A61K9/124 , A61K31/08 , A61K47/02 , A61K47/10 , A61K47/20 , A61K47/32 , A61M5/178 , A61M5/19 , A61M16/00 , A61M2202/00 , A61M2210/086 , A61M2210/12 , B01F3/04446 , B01F5/0685 , B01F5/0693 , B01F13/0023 , B65B31/00 , Y10S514/945
摘要: A therapeutic foam for the treatment of, inter alia, varicose veins comprises a sclerosing solution foamed with a physiological gas such as carbon dioxide, oxygen or a mixture thereof. The foam has a nitrogen content of less than 0.8%. It may be generated using a pressurised canister system incorporating a fine mesh of micron dimensions through which the gas and sclerosing liquid are passed to make the foam. Alternatively, the foam may be generated by passing gas and solution between two syringes through a fine mesh. Techniques are described for minimising the amount of nitrogen in a canister or syringe based product. A technique for generating and delivering foam simultaneously using a syringe based device is also disclosed.
摘要翻译: 用于治疗静脉曲张的治疗性泡沫包括用诸如二氧化碳,氧气或其混合物的生理气体发泡的硬化溶液。 泡沫的氮含量小于0.8%。 它可以使用包含微米尺寸的精细网格的加压罐系统来产生,气体和硬化液通过该微孔尺寸通过以制造泡沫。 或者,泡沫可以通过气体和溶液在两个注射器之间通过细网而产生。 描述了用于最小化基于罐或注射器的产品中氮的量的技术。 还公开了一种使用基于注射器的装置同时产生和递送泡沫的技术。
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公开(公告)号:US20060280690A1
公开(公告)日:2006-12-14
申请号:US10522529
申请日:2004-11-17
申请人: David Wright , Anthony Harman , Nikki Robinson , Garry Hodges , Adil Kadar , Geoffrey Moggridge , Hugh Van Liew
发明人: David Wright , Anthony Harman , Nikki Robinson , Garry Hodges , Adil Kadar , Geoffrey Moggridge , Hugh Van Liew
摘要: Present application discloses a device for generating and dispensing a foam for therapeutic use comprising a) a housing, b) a first chamber with gas at a substantially atmospheric pressure, a second chamber with at least one sclerosant agent c) an outlet for dispensing gas and the solution in the form of a foam d) the flow path for mixing the gas and the solution e) a foaming unit.
摘要翻译: 本申请公开了一种用于产生和分配用于治疗用途的泡沫的装置,包括:a)壳体,b)具有基本上大气压的气体的第一室,具有至少一种硬化剂的第二室; c)用于分配气体的出口和 以泡沫形式的溶液d)用于混合气体和溶液的流动路径e)发泡单元。
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公开(公告)号:US20060062736A1
公开(公告)日:2006-03-23
申请号:US10522525
申请日:2004-11-17
申请人: David Wright , Anthony Harman , Nikki Robinson , Garry Hodges , Adil Kadar
发明人: David Wright , Anthony Harman , Nikki Robinson , Garry Hodges , Adil Kadar
IPC分类号: A61L9/04
摘要: A therapeutic foam for the treatment of, inter alia, varicose veins comprises a sclerosing solution foamed with a physiological gas such as carbon dioxide, oxygen or a mixture thereof. The foam has a nitrogen content of less than 0.8%. It may be generated using a pressurised canister system incorporating a fine mesh of micron dimensions through which the gas and sclerosing liquid are passed to make the foam. Alternatively, the foam may be generated by passing gas and solution between two syringes through a fine mesh. Techniques are described for minimising the amount of nitrogen in a canister or syringe based product. A technique for generating and delivering foam simultaneously using a syringe based device is also disclosed.
摘要翻译: 用于治疗静脉曲张的治疗性泡沫包括用诸如二氧化碳,氧气或其混合物的生理气体发泡的硬化溶液。 泡沫的氮含量小于0.8%。 它可以使用包含微米尺寸的精细网格的加压罐系统来产生,气体和硬化液通过该微孔尺寸通过以制造泡沫。 或者,泡沫可以通过气体和溶液在两个注射器之间通过细网而产生。 描述了用于最小化基于罐或注射器的产品中氮的量的技术。 还公开了一种使用基于注射器的装置同时产生和递送泡沫的技术。
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公开(公告)号:US20070003489A1
公开(公告)日:2007-01-04
申请号:US11128265
申请日:2005-05-13
申请人: David Wright , Anthony Harman , Nikki Robinson , Garry Hodges , Adil Kadar
发明人: David Wright , Anthony Harman , Nikki Robinson , Garry Hodges , Adil Kadar
CPC分类号: A61K9/122
摘要: A therapeutic foam for the treatment of, inter alia, varicose veins comprises a sclerosing solution foamed with a physiological gas such as carbon dioxide, oxygen or a mixture thereof. The foam has a nitrogen content of less than 0.8%. It may be generated using a pressurised canister system incorporating a fine mesh of micron dimensions through which the gas and sclerosing liquid are passed to make the foam. Alternatively, the foam may be generated by passing gas and solution between two syringes through a fine mesh. Techniques are described for minimising the amount of nitrogen in a canister or syringe based product. A technique for generating and delivering foam simultaneously using a syringe based device is also disclosed.
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公开(公告)号:US20050266033A1
公开(公告)日:2005-12-01
申请号:US11171293
申请日:2005-07-01
IPC分类号: A61J3/00 , A61K9/12 , A61K47/04 , A61K47/20 , A61K47/34 , A61M5/31 , A61P9/14 , B65D83/14 , B65D83/16 , A61K9/00 , A61M37/00
CPC分类号: A61K9/122 , A61K9/0019 , A61K31/08 , B05B7/0037 , B05B11/02 , B65D83/14 , B65D83/20 , B65D83/48 , B65D83/60 , B65D83/62 , Y10S514/945
摘要: Improved therapeutic sclerosing microfoams and methods and devices for making them are provided that have advantage in producing a consistent profile injectable foam with minimal input by the physician yet using high volume percentages of blood dispersible gases, thus avoiding use of potentially hazardous amounts of nitrogen.
摘要翻译: 提供了改进的治疗性硬化微泡,以及用于制造它们的方法和装置,其具有生产一致的轮廓可注射泡沫的优点,医师具有最小的输入,但是使用高体积百分比的血液分散性气体,从而避免使用潜在的危险量的氮。
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公开(公告)号:US20070051426A1
公开(公告)日:2007-03-08
申请号:US10571608
申请日:2004-09-09
申请人: Anthony Harman , David Wright , Jam Mijers , Stuart Kay , Christopher Huristone , Julian Dixon , Andrew Pocock , Brendan Hogan
发明人: Anthony Harman , David Wright , Jam Mijers , Stuart Kay , Christopher Huristone , Julian Dixon , Andrew Pocock , Brendan Hogan
CPC分类号: B65D83/205 , B65B3/22 , B65D83/7532 , B65D83/756
摘要: A foam transfer device (600) is described, for use with aerosol canister apparatus for producing a sclerosant foam for the treatment of, inter alia, varicose veins. The device enables diversion of an initial quantity of below-specification foam from the canister to waste, e.g. to an integral waste chamber, before dispensing a further quantity of foam for use in treatment. The switching of the flow from the waste chamber to a different outlet (618) for use is accomplished without interrupting the flow from the aerosol canister since this would cause the foam to drop below specification again. The waste chamber may be transparent so that the foam entering it can be observed and a decision made by a user when to stop diverting foam to waste. Alternatively, the foam may be diverted automatically e.g. when a set time has elapsed or a set volume of foam dispensed. The foam for use is normally dispensed into a syringe for subsequent injection into a varicose vein of a patient.
摘要翻译: 描述了泡沫转移装置(600),用于气溶胶罐装置,用于产生用于治疗静脉曲张的硬化泡沫。 该装置能够将来自罐的初始数量低于规格的泡沫转移到废物,例如。 在分配更多量的泡沫以用于治疗之前,到整体的废物室。 在不中断来自气溶胶罐的流动的情况下,实现从废物室到不同出口(618)的流动切换,因为这将导致泡沫再次下降到规格以下。 废物室可以是透明的,使得可以观察到进入其中的泡沫,并且由用户决定何时停止将泡沫转移到废物中。 或者,泡沫可以自动转移,例如 当设定的时间过去或一定量的泡沫分配时。 使用的泡沫通常分配到注射器中,以便随后注射到患者的静脉曲张静脉中。
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公开(公告)号:US20050002873A1
公开(公告)日:2005-01-06
申请号:US10890267
申请日:2004-07-14
申请人: Anthony Harman , David Wright
发明人: Anthony Harman , David Wright
IPC分类号: A61B20060101 , A61K9/00 , A61K9/12 , A61K9/28 , B65D83/16
CPC分类号: A61K9/124 , A61K9/0019 , A61K31/08 , A61K33/00 , A61K45/06
摘要: A sclerosing foam comprising a physiologically acceptable gas that is readily dispersible in blood together with an aqueous sclerosant liquid is a microfoam further including one or more detectable gases selected from helium, neon, xenon, argon, sulfur hexafluoride and nitrous oxide, where the total volume of detectable gases comprises from 0.01% to 40% of the total volume of gas.
摘要翻译: 包含容易与水硬化液体一起分散在血液中的生理上可接受的气体的硬化泡沫是进一步包括一种或多种选自氦,氖,氙,氩,六氟化硫和一氧化二氮的可检测气体的微泡,其中总体积 的可检测气体占气体总体积的0.01%至40%。
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公开(公告)号:US08826932B2
公开(公告)日:2014-09-09
申请号:US12596222
申请日:2008-04-16
申请人: Michael Seal , Derek Sumsion , Anthony Harman
发明人: Michael Seal , Derek Sumsion , Anthony Harman
CPC分类号: E03C1/04 , E03C2201/30 , E03C2201/40 , Y10T137/2683 , Y10T137/86879 , Y10T137/87153 , Y10T137/87249 , Y10T137/87579 , Y10T137/87804
摘要: A diverter valve which is operable to divert a water supply to a spray includes an undiverted through passage for another water supply, such as filtered water.
摘要翻译: 可操作以将供水转移到喷雾器的分流阀包括用于另一个供水的未通过的通道,例如过滤的水。
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公开(公告)号:US20070031346A1
公开(公告)日:2007-02-08
申请号:US11580059
申请日:2006-10-13
申请人: Anthony Harman , Paul Harper , Neil Pollock , Gary Sinclair
发明人: Anthony Harman , Paul Harper , Neil Pollock , Gary Sinclair
CPC分类号: A61K9/122 , A61J1/2051 , A61J1/2055 , A61J1/2065 , A61J1/2096 , B65D81/3211 , B65D83/425 , Y10S514/945
摘要: A method for producing a microfoam suitable for use in scleropathy of blood vessels comprises introducing a physiologically acceptable blood-dispersible gas into a container (1) holding an aqueous sclerosant liquid and releasing the mixture of blood-dispersible gas and sclerosant liquid, whereby upon release of the mixture the components of the mixture interact to form a microfoam.
摘要翻译: 适用于血管硬化症的微泡的制造方法包括将生理学上可接受的血液分散性气体引入容纳含水硬化液的容器(1)中,释放出可分散血液和硬化液的混合物,由此释放 的混合物,混合物的组分相互作用形成微泡沫。
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