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公开(公告)号:US20160287527A1
公开(公告)日:2016-10-06
申请号:US15177687
申请日:2016-06-09
发明人: David Armbruster , James Dwyer , Jeffrey Chomyn , Sean Kerr
IPC分类号: A61K9/70 , B29C39/26 , C08J5/18 , B29C39/38 , A61K31/085 , A61K31/7036 , B29C39/24 , B29C39/02
CPC分类号: A61K9/7007 , A61B17/70 , A61B17/80 , A61B17/8028 , A61B2017/00004 , A61B2017/00526 , A61B2017/561 , A61F2/0063 , A61F2/0077 , A61F2/02 , A61F2/28 , A61F2/2846 , A61F2/30907 , A61F2002/30062 , A61F2002/30064 , A61F2002/30067 , A61F2002/30069 , A61F2002/30919 , A61F2013/00221 , A61F2013/00357 , A61F2210/0004 , A61F2250/0031 , A61F2250/0067 , A61K9/0024 , A61K31/085 , A61K31/7036 , A61L27/18 , A61L27/50 , A61L27/54 , A61L2300/604 , A61M31/002 , B29C39/003 , B29C39/026 , B29C39/24 , B29C39/26 , B29C39/38 , B29C41/02 , B29D7/01 , B29K2067/04 , B29K2067/043 , B29K2067/046 , B29K2105/0002 , B29K2105/0035 , B29K2105/0073 , B29K2995/006 , B29L2007/008 , B29L2031/753 , C08J5/18 , C08J2367/04 , C08J2369/00 , C08L67/04 , C08L69/005 , Y10S525/937 , Y10T428/24182 , Y10T428/24281 , Y10T428/24479 , Y10T428/25 , Y10T428/26
摘要: A flexible body comprises a polymer film having a first surface and an opposing second surface. The polymer film has a plurality of apertures extending from the first surface to the second surface and a plurality of raised lips protruding from the first surface such that each of the plurality of apertures is surrounded by one of the plurality of raised lips. A method of producing a polymer film comprises placing a polymer solution into a one sided mold having a plurality of protrusions extending from a bottom of the mold wherein the polymer solution is characterized by a viscosity that inhibits the unaided flow of the polymer throughout the mold; urging the polymer solution around each of the plurality of protrusions; and solidifying the polymer solution.
摘要翻译: 柔性体包括具有第一表面和相对的第二表面的聚合物膜。 聚合物膜具有从第一表面延伸到第二表面的多个孔,以及从第一表面突出的多个凸起的唇部,使得多个孔中的每一个被多个凸起的唇中的一个包围。 制备聚合物膜的方法包括将聚合物溶液放置在具有从模具底部延伸的多个突起的单面模具中,其中聚合物溶液的特征在于抑制聚合物在整个模具中的无支撑流动的粘度; 在所述多个突起中的每一个周围施加聚合物溶液; 并固化聚合物溶液。
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公开(公告)号:US20200061234A1
公开(公告)日:2020-02-27
申请号:US16672697
申请日:2019-11-04
发明人: David Armbruster , James Dwyer , Jeffrey Chomyn , Sean H. Kerr
摘要: Embodiments of the present disclosure are directed to perforated polymer films and methods of making the same. In some embodiments, the films are for use with implantable medical devices. In one embodiment there is a flexible body including a polymer film having a first surface and an opposing second surface, the film having a plurality of apertures extending from the first surface to the second surface and a plurality of raised lips protruding from the first surface such that each of the plurality of apertures is surrounded by a one of the plurality of raised lips. In one embodiment, the film comprises a single layer, and in another embodiment, the film can comprise a plurality of layers. In certain embodiments, the film can comprise an adhesive layer. In another embodiment, one or more of the layers may be a drug containing layer and/or a rate controlling layer for drug release.
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公开(公告)号:US11511019B2
公开(公告)日:2022-11-29
申请号:US16665134
申请日:2019-10-28
发明人: David Armbruster , Katlin Adlon Lumme , Jeffrey Chomyn , Aaron Yu
摘要: The present application discloses embodiments related to an implant and a method of forming an implant configured to treat a fractured bone. The implant can include a body having a proximal end, a distal end, and an outer surface extending from the proximal end to the distal end, wherein the body defines a central axis extending from the proximal end to the distal end; and a high tensile strand positioned adjacent the body such that at least a portion of the strand extends at least partially along the outer surface of the body in a direction substantially parallel with the central axis, and wherein the strand is loaded with an active agent.
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公开(公告)号:US20200054798A1
公开(公告)日:2020-02-20
申请号:US16665134
申请日:2019-10-28
发明人: David Armbruster , Katlin Adlon Lumme , Jeffrey Chomyn , Aaron Yu
摘要: The present application discloses embodiments related to an implant and a method of forming an implant configured to treat a fractured bone. The implant can include a body having a proximal end, a distal end, and an outer surface extending from the proximal end to the distal end, wherein the body defines a central axis extending from the proximal end to the distal end; and a high tensile strand positioned adjacent the body such that at least a portion of the strand extends at least partially along the outer surface of the body in a direction substantially parallel with the central axis, and wherein the strand is loaded with an active agent.
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公开(公告)号:US20160354523A1
公开(公告)日:2016-12-08
申请号:US15240210
申请日:2016-08-18
发明人: David Armbruster , Katlin Adlon Lumme , Jeffrey Chomyn , Aaron Yu
CPC分类号: A61L31/16 , A61B17/72 , A61B17/80 , A61B17/84 , A61B2017/00004 , A61B2017/561 , A61F2002/30677 , A61L2300/406 , A61L2430/02 , Y10T29/49826
摘要: The present application discloses embodiments related to an implant and a method of forming an implant configured to treat a fractured bone. The implant can include a body having a proximal end, a distal end, and an outer surface extending from the proximal end to the distal end, wherein the body defines a central axis extending from the proximal end to the distal end; and a high tensile strand positioned adjacent the body such that at least a portion of the strand extends at least partially along the outer surface of the body in a direction substantially parallel with the central axis, and wherein the strand is loaded with an active agent.
摘要翻译: 本申请公开了与植入物相关的实施例以及形成用于治疗骨折骨的植入物的方法。 植入物可以包括具有近端,远端和从近端延伸到远端的外表面的主体,其中主体限定从近端延伸到远端的中心轴线; 以及位于所述主体附近的高拉伸股线,使得所述股线的至少一部分沿着与所述中心轴线基本平行的方向至少部分地沿着所述主体的外表面延伸,并且其中所述股线装载有活性剂。
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公开(公告)号:US20200222335A1
公开(公告)日:2020-07-16
申请号:US16832406
申请日:2020-03-27
发明人: David Armbruster , James Dwyer , Jeffrey Chomyn , Sean Kerr
IPC分类号: A61K9/70 , B29C39/02 , B29C39/00 , A61L27/18 , A61L27/50 , A61L27/54 , A61K9/00 , A61B17/70 , A61B17/80 , B29D7/01 , B29C41/02 , C08J5/18 , A61K31/085 , A61K31/7036 , B29C39/24 , B29C39/26 , B29C39/38
摘要: A flexible body comprises a polymer film having a first surface and an opposing second surface. The polymer film has a plurality of apertures extending from the first surface to the second surface and a plurality of raised lips protruding from the first surface such that each of the plurality of apertures is surrounded by one of the plurality of raised lips. A method of producing a polymer film comprises placing a polymer solution into a one sided mold having a plurality of protrusions extending from a bottom of the mold wherein the polymer solution is characterized by a viscosity that inhibits the unaided flow of the polymer throughout the mold; urging the polymer solution around each of the plurality of protrusions; and solidifying the polymer solution.
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公开(公告)号:US20180028714A1
公开(公告)日:2018-02-01
申请号:US15725586
申请日:2017-10-05
发明人: David A. Armbruster , James Dwyer , Jeffrey Chomyn , Sean H. Kerr
CPC分类号: A61L24/0015 , A61B17/80 , A61B17/8057 , A61B17/8085 , A61B2017/00526 , A61F2/30907 , A61F2002/30677 , A61F2310/00389 , A61F2310/0097 , A61K9/7007 , A61L31/06 , A61L31/14 , A61L31/16 , A61L2430/02 , B32B3/266 , B32B2535/00 , C08L67/04
摘要: Embodiments of the present disclosure are directed to perforated polymer films and methods of making the same. In some embodiments, the films are for use with implantable medical devices. In one embodiment there is a flexible body including a polymer film having a first surface and an opposing second surface, the film having a plurality of apertures extending from the first surface to the second surface and a plurality of raised lips protruding from the first surface such that each of the plurality of apertures is surrounded by a one of the plurality of raised lips. In one embodiment, the film comprises a single layer, and in another embodiment, the film can comprise a plurality of layers. In certain embodiments, the film can comprise an adhesive layer. In another embodiment, one or more of the layers may be a drug containing layer and/or a rate controlling layer for drug release.
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公开(公告)号:US09440009B2
公开(公告)日:2016-09-13
申请号:US13767061
申请日:2013-02-14
发明人: David Armbruster , Katlin Adlon , Jeffrey Chomyn , Aaron Yu
CPC分类号: A61L31/16 , A61B17/72 , A61B17/80 , A61B17/84 , A61B2017/00004 , A61B2017/561 , A61F2002/30677 , A61L2300/406 , A61L2430/02 , Y10T29/49826
摘要: The present application discloses embodiments related to an implant and a method of forming an implant configured to treat a fractured bone. The implant can include a body having a proximal end, a distal end, and an outer surface extending from the proximal end to the distal end, wherein the body defines a central axis extending from the proximal end to the distal end; and a high tensile strand positioned adjacent the body such that at least a portion of the strand extends at least partially along the outer surface of the body in a direction substantially parallel with the central axis, and wherein the strand is loaded with an active agent.
摘要翻译: 本申请公开了与植入物相关的实施例以及形成用于治疗骨折骨的植入物的方法。 植入物可以包括具有近端,远端和从近端延伸到远端的外表面的主体,其中主体限定从近端延伸到远端的中心轴线; 以及位于所述主体附近的高拉伸股线,使得所述股线的至少一部分沿着与所述中心轴线基本平行的方向至少部分地沿着所述主体的外表面延伸,并且其中所述股线装载有活性剂。
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公开(公告)号:US09381683B2
公开(公告)日:2016-07-05
申请号:US13727682
申请日:2012-12-27
发明人: David Armbruster , James Dwyer , Jeffrey Chomyn , Sean Kerr
IPC分类号: A61F2/02 , A61F2/28 , B29C39/02 , B29C39/00 , A61B17/70 , A61B17/80 , B29D7/01 , B29C41/02 , C08J5/18 , A61L27/18 , A61L27/50 , A61L27/54 , A61K9/00 , A61K9/70 , A61F2/30 , C08L69/00 , C08L67/04 , A61F2/00 , A61B17/00 , A61B17/56 , B29K67/00 , A61F13/00
CPC分类号: A61K9/7007 , A61B17/70 , A61B17/80 , A61B2017/00004 , A61B2017/00526 , A61B2017/561 , A61F2/0063 , A61F2/0077 , A61F2/02 , A61F2/28 , A61F2/2846 , A61F2/30907 , A61F2002/30062 , A61F2002/30064 , A61F2002/30067 , A61F2002/30069 , A61F2002/30919 , A61F2013/00221 , A61F2013/00357 , A61F2210/0004 , A61F2250/0031 , A61F2250/0067 , A61K9/0024 , A61K31/085 , A61K31/7036 , A61L27/18 , A61L27/50 , A61L27/54 , A61L2300/604 , B29C39/003 , B29C39/026 , B29C39/24 , B29C39/26 , B29C39/38 , B29C41/02 , B29D7/01 , B29K2067/04 , B29K2067/043 , B29K2067/046 , B29K2105/0002 , B29K2105/0035 , B29K2105/0073 , B29K2995/006 , B29L2007/008 , B29L2031/753 , C08J5/18 , C08J2367/04 , C08J2369/00 , C08L67/04 , C08L69/005 , Y10S525/937 , Y10T428/24182 , Y10T428/24281 , Y10T428/24479 , Y10T428/25 , Y10T428/26
摘要: A flexible body comprises a polymer film having a first surface and an opposing second surface. The polymer film has a plurality of apertures extending from the first surface to the second surface and a plurality of raised lips protruding from the first surface such that each of the plurality of apertures is surrounded by one of the plurality of raised lips. A method of producing a polymer film comprises placing a polymer solution into a one sided mold having a plurality of protrusions extending from a bottom of the mold wherein the polymer solution is characterized by a viscosity that inhibits the unaided flow of the polymer throughout the mold; urging the polymer solution around each of the plurality of protrusions; and solidifying the polymer solution.
摘要翻译: 柔性体包括具有第一表面和相对的第二表面的聚合物膜。 聚合物膜具有从第一表面延伸到第二表面的多个孔,以及从第一表面突出的多个凸起的唇部,使得多个孔中的每一个被多个凸起的唇中的一个包围。 制备聚合物膜的方法包括将聚合物溶液放置在具有从模具底部延伸的多个突起的单面模具中,其中聚合物溶液的特征在于抑制聚合物在整个模具中的无支撑流动的粘度; 在所述多个突起中的每一个周围施加聚合物溶液; 并固化聚合物溶液。
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