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公开(公告)号:US20100040672A1
公开(公告)日:2010-02-18
申请号:US12481400
申请日:2009-06-09
申请人: Dean Ho , Robert Lam , Mark Chen , Houjin Huang , Erik Pierstorff , Erik Robinson
发明人: Dean Ho , Robert Lam , Mark Chen , Houjin Huang , Erik Pierstorff , Erik Robinson
IPC分类号: A61K9/70 , A61K31/56 , A61K31/351
CPC分类号: A61K31/573 , A61K9/0024 , A61K9/5115 , A61K9/7007 , A61K31/704 , A61K47/6957 , A61L27/34 , A61L27/54 , A61L2300/222 , A61L2300/41 , A61L2300/416 , A61L2300/602 , A61L2300/608 , A61L2300/624 , A61L2420/08 , C08L65/04
摘要: The present invention provides materials and devices for the controlled release of therapeutics, and methods for uses thereof.
摘要翻译: 本发明提供用于控制释放治疗剂的材料和装置及其用途的方法。
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公开(公告)号:US20100305309A1
公开(公告)日:2010-12-02
申请号:US12789966
申请日:2010-05-28
申请人: Dean Ho , Mark Chen , Erik Pierstorff , Erik Robinson , Robert Lam , Rafael Shimkunas , Xueqing Zhang
发明人: Dean Ho , Mark Chen , Erik Pierstorff , Erik Robinson , Robert Lam , Rafael Shimkunas , Xueqing Zhang
IPC分类号: C07K17/14 , C07H21/00 , C07C237/26
CPC分类号: C07K17/14 , A61K47/6921 , A61K47/6929 , B82Y5/00
摘要: The present invention provides various functionalized nanodiamond particles. In particular, the present invention provides soluble complexes of nanodiamond particles and therapeutic agents, for example insoluble therapeutics, anthracycline and/or tetracycline compounds, nucleic acids, proteins, etc.
摘要翻译: 本发明提供了各种官能化纳米金刚石颗粒。 特别地,本发明提供了纳米金刚石颗粒和治疗剂的可溶性复合物,例如不溶性治疗剂,蒽环类抗生素和/或四环素化合物,核酸,蛋白质等。
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公开(公告)号:US20130004560A1
公开(公告)日:2013-01-03
申请号:US13609588
申请日:2012-09-11
申请人: Dean Ho , Mark Chen , Erik Pierstorff , Houjin Huang , Edward K. Chow , Genhong Cheng
发明人: Dean Ho , Mark Chen , Erik Pierstorff , Houjin Huang , Edward K. Chow , Genhong Cheng
CPC分类号: A61L27/34 , A61L27/18 , A61L27/54 , A61L27/56 , A61L2300/41 , A61L2300/416 , A61L2300/606 , A61L2400/12 , Y10T428/24355 , Y10T428/24975 , C08L83/04 , C08L71/02
摘要: Disclosed herein are nanofilm coatings for implantable medical devices comprising a diblock or triblock copolymer (PEO-PMMA or PMOXA-PDMS-PMOXA, respectively). Such nanofilms, may be used, for example, as amphiphilic supports for therapeutic agents. These materials are conducive towards the formation of active substrates for a suite of biological and medical applications.
摘要翻译: 本文公开了包含二嵌段或三嵌段共聚物(分别为PEO-PMMA或PMOXA-PDMS-PMOXA)的可植入医疗装置的纳米薄膜。 这样的纳米膜可以用作例如治疗剂的两亲性载体。 这些材料有助于形成用于一系列生物和医学应用的活性底物。
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公开(公告)号:US08263104B2
公开(公告)日:2012-09-11
申请号:US12135640
申请日:2008-06-09
申请人: Dean Ho , Mark Chen , Erik Pierstorff , Houjin Huang , Edward K Chow , Genhong Cheng
发明人: Dean Ho , Mark Chen , Erik Pierstorff , Houjin Huang , Edward K Chow , Genhong Cheng
CPC分类号: A61L27/34 , A61L27/18 , A61L27/54 , A61L27/56 , A61L2300/41 , A61L2300/416 , A61L2300/606 , A61L2400/12 , Y10T428/24355 , Y10T428/24975 , C08L83/04 , C08L71/02
摘要: Disclosed herein are nanofilm coatings for implantable medical devices comprising a diblock or triblock copolymer (PEO-PMMA or PMOXA-PDMS-PMOXA, respectively). Such nanofilms, may be used, for example, as amphiphilic supports for therapeutic agents. These materials are conducive towards the formation of active substrates for a suite of biological and medical applications.
摘要翻译: 本文公开了包含二嵌段或三嵌段共聚物(分别为PEO-PMMA或PMOXA-PDMS-PMOXA)的可植入医疗装置的纳米薄膜。 这样的纳米膜可以用作例如治疗剂的两亲性载体。 这些材料有助于形成用于一系列生物和医学应用的活性底物。
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公开(公告)号:US20090004241A1
公开(公告)日:2009-01-01
申请号:US12135640
申请日:2008-06-09
申请人: Dean Ho , Mark Chen , Erik Pierstorff , Houjin Huang , Edward K. Chow , Genhong Cheng
发明人: Dean Ho , Mark Chen , Erik Pierstorff , Houjin Huang , Edward K. Chow , Genhong Cheng
CPC分类号: A61L27/34 , A61L27/18 , A61L27/54 , A61L27/56 , A61L2300/41 , A61L2300/416 , A61L2300/606 , A61L2400/12 , Y10T428/24355 , Y10T428/24975 , C08L83/04 , C08L71/02
摘要: Disclosed herein are nanofilm coatings for implantable medical devices comprising a diblock or triblock copolymer (PEO-PMMA or PMOXA-PDMS-PMOXA, respectively). Such nanofilms, may be used, for example, as amphiphilic supports for therapeutic agents. These materials are conducive towards the formation of active substrates for a suite of biological and medical applications.
摘要翻译: 本文公开了包含二嵌段或三嵌段共聚物(分别为PEO-PMMA或PMOXA-PDMS-PMOXA)的可植入医疗装置的纳米薄膜。 这样的纳米膜可以用作例如治疗剂的两亲性载体。 这些材料有助于形成用于一系列生物和医学应用的活性底物。
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公开(公告)号:US09172186B2
公开(公告)日:2015-10-27
申请号:US13657866
申请日:2012-10-23
IPC分类号: H01R13/64 , H01R13/642
CPC分类号: H01R13/64 , H01R13/642 , H01R24/64
摘要: An anti-misinsertion structure of a socket connector includes a pivot clasped to both sides of the top of an insulating base of the socket connector and two connecting arms extended horizontally from both sides of the pivot. Each connecting arm has a guide piece extended horizontally from an end of each connecting arm, a stop piece formed at the bottom of the connecting arm and proximate to the guide piece of the connecting arm, a downwardly tilted first guide bevel formed at the bottom of the guide piece, a position limit surface defined on a side of the guide piece and proximate to the stop piece, an upwardly tilted second guide bevel formed at the bottom of the stop piece, and a stop surface defined on a side of the stop piece and proximate to the guide piece and perpendicular to the position limit surface of the guide piece.
摘要翻译: 插座连接器的防误插入结构包括紧固在插座连接器的绝缘基座的顶部的两侧的枢轴和从枢轴的两侧水平延伸的两个连接臂。 每个连接臂具有从每个连接臂的端部水平延伸的引导件,形成在连接臂的底部并且靠近连接臂的引导件的止挡件,形成在底部的向下倾斜的第一引导斜面 所述引导件是限定在所述引导件的一侧并且靠近所述止挡件的位置限制表面,形成在所述止挡件的底部的向上倾斜的第二引导斜面,以及限定在所述止动件 并且靠近引导件并且垂直于引导件的位置限制表面。
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公开(公告)号:US08424817B1
公开(公告)日:2013-04-23
申请号:US13317715
申请日:2011-10-26
申请人: Mark Chen
发明人: Mark Chen
摘要: An article holder includes a base having a chamber and two opposite grooves, and having two ears, a follower having two projections slidably engaged with the grooves of the base and having a latching tongue, a carrier member having a pivot shaft extended from a protrusion and pivotally engaged with the ears of the base and having an engaging cavity, a spring member biases the latching tongue to engage with the engaging cavity of the carrier member at a working position, the carrier member is pivotal relative to the base to a storing position when the latching tongue of the follower is disengaged from the engaging cavity of the carrier member, a gripping block is pivotally attached to the carrier member and biased to engage with an article.
摘要翻译: 物品保持器包括具有腔室和两个相对的凹槽的底座,并且具有两个耳朵;从动件,具有两个突起,其与基座的凹槽可滑动地接合并具有闩锁舌;承载构件,具有从突出部延伸的枢轴; 枢转地与基部的耳朵接合并具有接合空腔,弹簧构件偏压闩锁舌片以在工作位置处与承载构件的接合腔体接合,承载构件相对于基座枢转到存储位置,当存储位置 从动件的闩锁舌片与承载构件的接合腔脱离,把持块枢转地附接到承载构件并被偏压以与制品接合。
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公开(公告)号:US20060150780A1
公开(公告)日:2006-07-13
申请号:US11031043
申请日:2005-01-10
申请人: Mark Chen
发明人: Mark Chen
CPC分类号: B23B51/00 , B23B2260/124 , B25B27/18
摘要: This artistic creation relates to a tool for removing screws with damaged heads. The tool comprises of a screw-removing section and a hold section. The screw-removing section extends a central drill involving a tip and composite angles, so as to remove the broken screws with even heads and avoid incline in operating. Moreover, the sunken relief surfaces of the screw-removing section form scraping edges with strong stress resistance. Some recesses on the scraping surfaces enhance resistance to dig into the heads of deformed screws and are apt to remove the broken screws. More specifically, this invention relates to such a bit especially adapted for use in a power drill running in a counter-clockwise direction.
摘要翻译: 这种艺术创作涉及用于去除损坏头部的螺丝的工具。 该工具包括螺丝去除部和保持部。 螺丝去除部分延伸中心钻头涉及尖端和复合角度,以便去除具有均匀头部的破碎的螺钉,并避免操作中的倾斜。 此外,螺纹除去部的下沉的浮雕表面形成具有强应力阻力的刮削刃。 刮削表面上的一些凹陷提高了抵抗变形螺钉头部的阻力,并且易于拆下破碎的螺钉。 更具体地,本发明涉及特别适用于在逆时针方向上运行的电钻的这种钻头。
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公开(公告)号:US06589122B1
公开(公告)日:2003-07-08
申请号:US10099383
申请日:2002-03-18
申请人: Mark Chen
发明人: Mark Chen
IPC分类号: B21J1302
CPC分类号: B23G9/009 , Y10T408/904
摘要: A thread tapping device has a main seat, a rotating head, a handle rod, an adjustment rod, a pivot connector, and a pair of scrape blades. The main seat has a V-shaped groove, a bottom pivot hole, a through aperture, two connection bars, and an end block. The rotating head is disposed on the handle rod and inserted in the bottom pivot hole of the main seat. The adjustment rod has an upper lug and an outer threaded portion inserted in the rotating head. The pivot connector has a round aperture, a circular aperture, and a lower groove to receive the upper lug of the adjustment rod. Each scrape blade is disposed between the end block and one of the connection bars.
摘要翻译: 螺纹攻丝装置具有主座椅,旋转头,手柄杆,调节杆,枢轴连接器和一对刮刀。 主座具有V形槽,底部枢轴孔,通孔,两个连接杆和端块。 旋转头设置在把手上并插入主座的底部枢轴孔中。 调节杆具有插入旋转头部的上凸耳和外螺纹部分。 枢转连接器具有圆形孔,圆形孔和下槽,以容纳调节杆的上凸耳。 每个刮刀设置在端块与一个连接杆之间。
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公开(公告)号:US06442781B1
公开(公告)日:2002-09-03
申请号:US09881186
申请日:2001-06-12
申请人: Mark Chen
发明人: Mark Chen
IPC分类号: B25F100
摘要: A plane saw assembly has a handle, a nut inserted in the handle, a hollow plane saw connected to the handle, a hollow plug inserted in the hollow plane saw and the handle, a bolt inserted in the hollow plug, a collar receiving the hollow plane saw, and a drill device having a threaded post inserted in the collar. The hollow plane saw has an end slot, a large number of plane blades, and a large number of through holes matching the plane blades. Each of the plane blades has a cutting edge.
摘要翻译: 平面锯组件具有手柄,插入手柄中的螺母,连接到手柄的中空平面锯,插入中空平面锯和手柄的中空塞子,插入中空塞子中的螺栓,容纳中空部件的轴环 平面锯和具有插入轴环中的螺纹柱的钻孔装置。 中空平面锯具有端槽,多个平面叶片和与平面叶片匹配的大量通孔。 每个平面叶片具有切割边缘。
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