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1.发明授权公开(公告)号：US09289925B2
公开(公告)日：2016-03-22
申请号：US13262996
申请日：2010-03-22
申请人： Dennis E. Ferguson , Stanley Rendon
发明人： Dennis E. Ferguson , Stanley Rendon
CPC分类号： B29C43/021 , A61B2010/008 , A61M37/0015 , A61M2037/003 , A61M2037/0053 , B29C33/0088 , B29C33/301 , B29C45/37 , B29C2043/025 , B29C2045/0094 , B29L2031/7544 , B29L2031/756
摘要： A method of making hollow microneedle arrays is described. Also described are the articles therefrom and the use of the articles in applications such as delivering fluid to and/or extracting body fluid from a subject.
摘要翻译： 描述了制造中空微针阵列的方法。 还描述了它们的制品，以及在诸如从受试者中输送流体和/或从体内提取体液的应用中使用制品。
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公开(公告)号：US08236231B2
公开(公告)日：2012-08-07
申请号：US12600557
申请日：2008-06-18
申请人： Dennis E. Ferguson , Satinder K. Nayar , Peter T. Benson , Stanley Rendon , Donald L. Pochardt , James N. Dobbs , Daniel H. Carlson
发明人： Dennis E. Ferguson , Satinder K. Nayar , Peter T. Benson , Stanley Rendon , Donald L. Pochardt , James N. Dobbs , Daniel H. Carlson
IPC分类号： B29C45/73
CPC分类号： B29C45/14016 , A61M37/0015 , A61M2037/0053 , B01F13/0827 , B29C45/14 , B29C45/1634 , B29C45/1671 , B29C45/27 , B29C45/34 , B29C45/568 , B29C45/73 , B29C2035/0811 , B29C2045/0094 , B29C2045/14942 , B29C2045/2683 , B29C2791/008 , B29D11/00009 , B29K2069/00 , B29K2669/00 , B29L2011/0016 , B29L2031/753 , B29L2031/756 , B32B3/10 , G02B3/00 , Y10T428/24355 , Y10T428/24479 , Y10T428/24612 , Y10T428/24802 , Y10T428/2481 , Y10T428/24917
摘要： Injection molding, parts onto a carrier web (34) located between mold halves (18,20). Flow of polymer melt into the mold is assisted by application of ultrasonic energy to the mold cavity. After the molding operation, mold halves are separated, and the carrier web is advanced, or indexed, to a next position for another molding sequence. Molding apparatus comprises a moving mold face (20), that can move toward and away from a first mold member (18) (which can be stationary) in which the mold cavity is located, a means (24,25,26,30,32) for moving and/or indexing carrier web between the first mold member and the moving mold face, means (16) to inject polymer melt into the mold cavity, and an ultrasonic system (42) providing ultrasonic energy to the mold cavity. The carrier web can transport molded parts to subsequent process steps, such as coating, drying, inspection, curing, assembly or packaging.
摘要翻译： 将部件注射到位于半模（18,20）之间的载体网（34）上。 聚合物熔体进入模具的流程通过向模腔施加超声波能量来辅助。 在模制操作之后，将半模分开，并且将载体网推进或分度到另一模制顺序的下一位置。 成型设备包括移动的模具面（20），其可朝向和远离模具腔所在的第一模具构件（18）（其可以是静止的）移动;一个装置（24,25,26,30， 32），用于在第一模具构件和移动模具面之间移动和/或分度载体网，用于将聚合物熔体注入模腔中的装置（16）以及向模腔提供超声波能量的超声波系统（42）。 载体网可以将模制零件输送到随后的工艺步骤，例如涂覆，干燥，检查，固化，组装或包装。
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公开(公告)号：US20130345384A1
公开(公告)日：2013-12-26
申请号：US14003045
申请日：2012-03-14
申请人： Stanley Rendon , Dennis E. Ferguson , Donald L. Pochardt , Joseph S. Warner , Timothy J. Rowell , Peter T. Benson , Satinder K. Nayar
发明人： Stanley Rendon , Dennis E. Ferguson , Donald L. Pochardt , Joseph S. Warner , Timothy J. Rowell , Peter T. Benson , Satinder K. Nayar
IPC分类号： B29C45/73 , C08F220/06
CPC分类号： B29C45/73 , B29C45/0025 , B29C45/568 , B29C45/7207 , B29C2045/7393 , B29L2011/00 , C08F220/06
摘要： An ultrasonic-assisted injection molding system and method for making precisely-shaped articles. A source of ultrasonic energy is positioned to apply vibrational energy to a mold cavity connected to at least one gate in flow communication with a source of molten (co)polymer. The mold is heated to a temperature of 104-116° C., and the molten (co)polymer is injected into the mold cavity. After cooling the mold until the molten (co)polymer within the gate has solidified, ultrasonic energy is applied to the mold without remelting the solidified (co)polymer within the gate until the temperature increases to 116-122° C., thereby substantially relieving flow induced stresses. The mold is then cooled until the temperature decreases to 101-107° C., and is thereafter heated until the temperature increases to 116-122° C., thereby substantially relieving any thermally induced stresses. The mold is cooled until the molten (co)polymer has solidified, thereby forming a precision molded plastic optical element.
摘要翻译： 超声波辅助注射成型系统及制造精密成形制品的方法。 定位超声波能源，以将振动能施加到与熔融（共）聚合物源流动连通的至少一个浇口连接的模腔上。 将模具加热到104-116℃的温度，并将熔融的（共）聚合物注入模腔中。 在模具冷却之后，门内的熔融（共）聚合物已经固化，超声波能量被施加到模具上，而不使固化的（共）聚合物在浇口内重熔，直到温度升至116-122℃，从而基本上缓解 流动应力。 然后将模具冷却直到温度降至101-107℃，然后加热直到温度升至116-122℃，从而基本上减轻任何热诱导的应力。 将模具冷却直到熔融（共）聚合物固化，从而形成精密模塑塑料光学元件。
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公开(公告)号：US08449807B2
公开(公告)日：2013-05-28
申请号：US13530382
申请日：2012-06-22
申请人： Dennis E. Ferguson , Satinder K. Nayar , Peter T. Benson , Stanley Rendon , Donald L. Pochardt , Daniel H. Carlson
发明人： Dennis E. Ferguson , Satinder K. Nayar , Peter T. Benson , Stanley Rendon , Donald L. Pochardt , Daniel H. Carlson
IPC分类号： B29C45/14
CPC分类号： B29C45/14016 , A61M37/0015 , A61M2037/0053 , B01F13/0827 , B29C45/14 , B29C45/1634 , B29C45/1671 , B29C45/27 , B29C45/34 , B29C45/568 , B29C45/73 , B29C2035/0811 , B29C2045/0094 , B29C2045/14942 , B29C2045/2683 , B29C2791/008 , B29D11/00009 , B29K2069/00 , B29K2669/00 , B29L2011/0016 , B29L2031/753 , B29L2031/756 , B32B3/10 , G02B3/00 , Y10T428/24355 , Y10T428/24479 , Y10T428/24612 , Y10T428/24802 , Y10T428/2481 , Y10T428/24917
摘要： Injection molding parts onto a carrier web located between mold halves, each mold half having a cavity, resulting in molded articles having parts on both sides of the carrier web. Polymer flow into the cavities is assisted by application of ultrasonic energy to the mold. After the molding operation, mold halves are separated, and the carrier web is advanced, or indexed, to a next position for another molding sequence. Articles produced include lenses with part of the carrier web between lens halves, and a carrier web bearing an array of molded parts.
摘要翻译： 将注模部件注射到位于半模之间的载体网上，每个半模具有空腔，导致模制品在载体网的两侧具有部分。 通过向模具中施加超声能量来辅助进入空腔的聚合物流。 在模制操作之后，将半模分开，并且将载体网推进或分度到另一模制顺序的下一位置。 产生的制品包括具有半透镜之间的载体网的一部分的透镜以及具有模制部件阵列的载体网。
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公开(公告)号：US09289931B2
公开(公告)日：2016-03-22
申请号：US14003045
申请日：2012-03-14
申请人： Stanley Rendon , Dennis E. Ferguson , Donald L. Pochardt , Joseph S. Warner , Timothy J. Rowell , Peter T. Benson , Satinder K. Nayar
发明人： Stanley Rendon , Dennis E. Ferguson , Donald L. Pochardt , Joseph S. Warner , Timothy J. Rowell , Peter T. Benson , Satinder K. Nayar
CPC分类号： B29C45/73 , B29C45/0025 , B29C45/568 , B29C45/7207 , B29C2045/7393 , B29L2011/00 , C08F220/06
摘要： An ultrasonic-assisted injection molding system and method for making precisely-shaped articles. A source of ultrasonic energy is positioned to apply vibrational energy to a mold cavity connected to at least one gate in flow communication with a source of molten (co)polymer. The mold is heated to a temperature of 104-116° C., and the molten (co)polymer is injected into the mold cavity. After cooling the mold until the molten (co)polymer within the gate has solidified, ultrasonic energy is applied to the mold without remelting the solidified (co)polymer within the gate until the temperature increases to 116-122° C., thereby substantially relieving flow induced stresses. The mold is then cooled until the temperature decreases to 101-107° C., and is thereafter heated until the temperature increases to 116-122° C., thereby substantially relieving any thermally induced stresses. The mold is cooled until the molten (co)polymer has solidified, thereby forming a precision molded plastic optical element.
摘要翻译： 超声波辅助注射成型系统及制造精密成形制品的方法。 定位超声波能源，以将振动能施加到与熔融（共）聚合物源流动连通的至少一个浇口连接的模腔上。 将模具加热到104-116℃的温度，并将熔融的（共）聚合物注入模腔中。 在模具冷却之后，门内的熔融（共）聚合物已经固化，超声波能量被施加到模具上，而不使固化的（共）聚合物在浇口内重熔，直到温度升至116-122℃，从而基本上缓解 流动应力。 然后将模具冷却直到温度降至101-107℃，然后加热直到温度升至116-122℃，从而基本上减轻任何热诱导的应力。 将模具冷却直到熔融（共）聚合物固化，从而形成精密模塑塑料光学元件。
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公开(公告)号：US08637136B2
公开(公告)日：2014-01-28
申请号：US13530256
申请日：2012-06-22
CPC分类号： B29C45/14016 , A61M37/0015 , A61M2037/0053 , B01F13/0827 , B29C45/14 , B29C45/1634 , B29C45/1671 , B29C45/27 , B29C45/34 , B29C45/568 , B29C45/73 , B29C2035/0811 , B29C2045/0094 , B29C2045/14942 , B29C2045/2683 , B29C2791/008 , B29D11/00009 , B29K2069/00 , B29K2669/00 , B29L2011/0016 , B29L2031/753 , B29L2031/756 , B32B3/10 , G02B3/00 , Y10T428/24355 , Y10T428/24479 , Y10T428/24612 , Y10T428/24802 , Y10T428/2481 , Y10T428/24917
摘要： Articles enabled by an injection molding process that molds parts on a carrier web located between mold halves and uses ultrasonic energy to assist flow of polymer melt into the mold cavity. One such article is a carrier web having a high density of molded parts, i.e., bearing an array of molded articles adhered to the web in rows and columns, the articles being spaced closer (center-to-center or edge-to-edge) than the diagonal spacing between articles in the next adjacent row and next adjacent column. Another such article is a microneedle array on a land no more than 250 μm thick on which at least 60% of the microneedles across the array are filled (i.e., completely formed).
摘要翻译： 通过注射成型工艺实现的制品，其模制位于半模之间的载体网上的部件并且使用超声波能量以帮助聚合物熔体流入模腔。 一种这样的制品是具有高密度模制部件的载体网，即以行和列方式附着到卷材上的模制品的阵列，物品间隔得更近（中心到中心或边缘到边缘） 比下一个相邻行和下一个相邻列中的物品之间的对角线间隔。 另一种这样的制品是在不超过250μm厚的地面上的微针阵列，其上穿过阵列的至少60％的微针被填充（即完全形成）。
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公开(公告)号：US20120263919A1
公开(公告)日：2012-10-18
申请号：US13530256
申请日：2012-06-22
申请人： Dennis E. Ferguson , Satinder K. Nayar , Peter T. Benson , Stanley Rendon , Donald L. Pochardt , James N. Dobbs , Daniel H. Carlson
发明人： Dennis E. Ferguson , Satinder K. Nayar , Peter T. Benson , Stanley Rendon , Donald L. Pochardt , James N. Dobbs , Daniel H. Carlson
CPC分类号： B29C45/14016 , A61M37/0015 , A61M2037/0053 , B01F13/0827 , B29C45/14 , B29C45/1634 , B29C45/1671 , B29C45/27 , B29C45/34 , B29C45/568 , B29C45/73 , B29C2035/0811 , B29C2045/0094 , B29C2045/14942 , B29C2045/2683 , B29C2791/008 , B29D11/00009 , B29K2069/00 , B29K2669/00 , B29L2011/0016 , B29L2031/753 , B29L2031/756 , B32B3/10 , G02B3/00 , Y10T428/24355 , Y10T428/24479 , Y10T428/24612 , Y10T428/24802 , Y10T428/2481 , Y10T428/24917
摘要： Articles enabled by an injection molding process that molds parts on a carrier web located between mold halves and uses ultrasonic energy to assist flow of polymer melt into the mold cavity. One such article is a carrier web having a high density of molded parts, i.e., bearing an array of molded articles adhered to the web in rows and columns, the articles being spaced closer (center-to-center or edge-to-edge) than the diagonal spacing between articles in the next adjacent row and next adjacent column. Another such article is a microneedle array on a land no more than 250 μm thick on which at least 60% of the microneedles across the array are filled (i.e., completely formed).
摘要翻译： 通过注射成型工艺实现的制品，其模制位于半模之间的载体网上的部件并且使用超声波能量以帮助聚合物熔体流入模腔。 一种这样的制品是具有高密度模制部件的载体网，即以行和列方式附着到卷材上的模制品的阵列，物品间隔得更近（中心到中心或边缘到边缘） 比下一个相邻行和下一个相邻列中的物品之间的对角线间隔。 另一种这样的制品是在不超过250μm厚的地面上的微针阵列，其上穿过阵列的至少60％的微针被填充（即完全形成）。
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公开(公告)号：US20120262796A1
公开(公告)日：2012-10-18
申请号：US13530382
申请日：2012-06-22
申请人： Dennis E. Ferguson , Satinder K. Nayar , Peter T. Benson , Stanley Rendon , Donald L. Pochardt , James N. Dobbs , Daniel H. Carlson
发明人： Dennis E. Ferguson , Satinder K. Nayar , Peter T. Benson , Stanley Rendon , Donald L. Pochardt , James N. Dobbs , Daniel H. Carlson
CPC分类号： B29C45/14016 , A61M37/0015 , A61M2037/0053 , B01F13/0827 , B29C45/14 , B29C45/1634 , B29C45/1671 , B29C45/27 , B29C45/34 , B29C45/568 , B29C45/73 , B29C2035/0811 , B29C2045/0094 , B29C2045/14942 , B29C2045/2683 , B29C2791/008 , B29D11/00009 , B29K2069/00 , B29K2669/00 , B29L2011/0016 , B29L2031/753 , B29L2031/756 , B32B3/10 , G02B3/00 , Y10T428/24355 , Y10T428/24479 , Y10T428/24612 , Y10T428/24802 , Y10T428/2481 , Y10T428/24917
摘要： Injection molding parts onto a carrier web located between mold halves, each mold half having a cavity, resulting in molded articles having parts on both sides of the carrier web. Polymer flow into the cavities is assisted by application of ultrasonic energy to the mold. After the molding operation, mold halves are separated, and the carrier web is advanced, or indexed, to a next position for another molding sequence. Articles produced include lenses with part of the carrier web between lens halves, and a carrier web bearing an array of molded parts.
摘要翻译： 将注模部件注射到位于半模之间的载体网上，每个半模具有空腔，导致模制品在载体网的两侧具有部分。 通过向模具中施加超声能量来辅助进入空腔的聚合物流。 在模制操作之后，将半模分开，并且将载体网推进或分度到另一模制顺序的下一位置。 产生的制品包括具有半透镜之间的载体网的一部分的透镜以及具有模制部件阵列的载体网。
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9.发明申请公开(公告)号：US20120041337A1
公开(公告)日：2012-02-16
申请号：US13262996
申请日：2010-03-22
申请人： Dennis E. Ferguson , Stanley Rendon
发明人： Dennis E. Ferguson , Stanley Rendon
CPC分类号： B29C43/021 , A61B2010/008 , A61M37/0015 , A61M2037/003 , A61M2037/0053 , B29C33/0088 , B29C33/301 , B29C45/37 , B29C2043/025 , B29C2045/0094 , B29L2031/7544 , B29L2031/756
摘要： A method of making hollow microneedle arrays is described. Also described are the articles therefrom and the use of the articles in applications such as delivering fluid to and/or extracting body fluid from a subject.
摘要翻译： 描述了制造中空微针阵列的方法。 还描述了它们的制品，以及在诸如从受试者中输送流体和/或从体内提取体液的应用中使用制品。
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公开(公告)号：US20100159197A1
公开(公告)日：2010-06-24
申请号：US12600557
申请日：2008-06-18
申请人： Dennis E. Ferguson , Satinder K. Nayar , Peter T. Benson , Stanley Rendon , Donald L. Pochardt , James N. Dobbs , Daniel H. Carlson
发明人： Dennis E. Ferguson , Satinder K. Nayar , Peter T. Benson , Stanley Rendon , Donald L. Pochardt , James N. Dobbs , Daniel H. Carlson
CPC分类号： B29C45/14016 , A61M37/0015 , A61M2037/0053 , B01F13/0827 , B29C45/14 , B29C45/1634 , B29C45/1671 , B29C45/27 , B29C45/34 , B29C45/568 , B29C45/73 , B29C2035/0811 , B29C2045/0094 , B29C2045/14942 , B29C2045/2683 , B29C2791/008 , B29D11/00009 , B29K2069/00 , B29K2669/00 , B29L2011/0016 , B29L2031/753 , B29L2031/756 , B32B3/10 , G02B3/00 , Y10T428/24355 , Y10T428/24479 , Y10T428/24612 , Y10T428/24802 , Y10T428/2481 , Y10T428/24917
摘要： Injection molding, parts onto a carrier web (34) located between mold halves (18,20). Flow of polymer melt into the mold is assisted by application of ultrasonic energy to the mold cavity. After the molding operation, mold halves are separated, and the carrier web is advanced, or indexed, to a next position for another molding sequence. Molding apparatus comprises a moving mold face (20), that can move toward and away from a first mold member (18) (which can be stationary) in which the mold cavity is located, a means (24,25,26,30,32) for moving and/or indexing carrier web between the first mold member and the moving mold face, means (16) to inject polymer melt into the mold cavity, and an ultrasonic system (42) providing ultrasonic energy to the mold cavity. The carrier web can transport molded parts to subsequent process steps, such as coating, drying, inspection, curing, assembly or packaging.
摘要翻译： 将部件注射到位于半模（18,20）之间的载体网（34）上。 聚合物熔体进入模具的流程通过向模腔施加超声波能量来辅助。 在模制操作之后，将半模分开，并且将载体网推进或分度到另一模制顺序的下一位置。 成型设备包括移动的模具面（20），该移动的模具面可朝向和远离模具腔位于其中的第一模具构件（18）移动（24,25,26,30， 32），用于在第一模具构件和移动模具面之间移动和/或分度载体网，用于将聚合物熔体注入模腔中的装置（16）以及向模腔提供超声波能量的超声波系统（42）。 载体网可以将模制零件输送到随后的工艺步骤，例如涂覆，干燥，检查，固化，组装或包装。
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