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公开(公告)号:US07867749B2
公开(公告)日:2011-01-11
申请号:US11326080
申请日:2006-01-05
申请人: Deryck J. Williams , Merry B. McLaird , Michelle Coutu Hresko , Anita M. Frevert-Thompson , Ronald E. Worthington , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
发明人: Deryck J. Williams , Merry B. McLaird , Michelle Coutu Hresko , Anita M. Frevert-Thompson , Ronald E. Worthington , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
CPC分类号: C12N9/1007
摘要: Nucleic acid molecules from nematodes encoding phosphoethanolamine n-methyltransferase polypeptides are described. PEAMT-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PEAMT-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
摘要翻译: 描述了编码磷酸乙醇胺正甲基转移酶多肽的线虫的核酸分子。 还提供了PEAMT样多肽序列,载体,宿主细胞和用于产生PEAMT样核苷酸和多肽的重组方法也是如此。 还描述了用于鉴定抑制剂和/或激活剂的筛选方法以及用于抗体生产的方法。
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公开(公告)号:US07442533B2
公开(公告)日:2008-10-28
申请号:US10602268
申请日:2003-06-23
申请人: Deryck J. Williams , Merry B. McLaird , Michelle Coutu Hresko , Anita M. Frevert , Ronald E. Worthington , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
发明人: Deryck J. Williams , Merry B. McLaird , Michelle Coutu Hresko , Anita M. Frevert , Ronald E. Worthington , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
CPC分类号: C12N9/1007
摘要: Nucleic acid molecules from nematodes encoding phosphoethanolamine n-methyltransferase polypeptides are described. PEAMT-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PEAMT-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
摘要翻译: 描述了编码磷酸乙醇胺正甲基转移酶多肽的线虫的核酸分子。 还提供了PEAMT样多肽序列,载体,宿主细胞和用于产生PEAMT样核苷酸和多肽的重组方法也是如此。 还描述了用于鉴定抑制剂和/或激活剂的筛选方法以及用于抗体生产的方法。
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公开(公告)号:US08198060B2
公开(公告)日:2012-06-12
申请号:US12260071
申请日:2008-10-28
申请人: Deryck J. Williams , Merry B. McLaird , Michelle Coutu Hresko , Anita M. Frevert , Ronald E. Worthington , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
发明人: Deryck J. Williams , Merry B. McLaird , Michelle Coutu Hresko , Anita M. Frevert , Ronald E. Worthington , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
IPC分类号: C12N9/12
CPC分类号: C12N9/1007
摘要: Nucleic acid molecules from nematodes encoding phosphoethanolamine n-methyltransferase polypeptides are described. PEAMT-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PEAMT-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
摘要翻译: 描述了编码磷酸乙醇胺正甲基转移酶多肽的线虫的核酸分子。 还提供了PEAMT样多肽序列,载体,宿主细胞和用于产生PEAMT样核苷酸和多肽的重组方法也是如此。 还描述了用于鉴定抑制剂和/或激活剂的筛选方法以及用于抗体生产的方法。
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公开(公告)号:US20090123986A1
公开(公告)日:2009-05-14
申请号:US12260071
申请日:2008-10-28
申请人: Deryck J. Williams , Merry B. McLaird , Michelle Coutu Hresko , Anita M. Frevert , Ronald E. Worthington , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
发明人: Deryck J. Williams , Merry B. McLaird , Michelle Coutu Hresko , Anita M. Frevert , Ronald E. Worthington , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
IPC分类号: C12N9/10
CPC分类号: C12N9/1007
摘要: Nucleic acid molecules from nematodes encoding phosphoethanolamine n-methyltransferase polypeptides are described. PEAMT-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PEAMT-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
摘要翻译: 描述了编码磷酸乙醇胺正甲基转移酶多肽的线虫的核酸分子。 还提供了PEAMT样多肽序列,载体,宿主细胞和用于产生PEAMT样核苷酸和多肽的重组方法也是如此。 还描述了用于鉴定抑制剂和/或激活剂的筛选方法以及用于抗体生产的方法。
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公开(公告)号:US07339044B2
公开(公告)日:2008-03-04
申请号:US11191588
申请日:2005-07-28
申请人: Michelle Coutu Hresko , Merry B. McLaird , Deryck J. Williams , Anita M. Frevert , Brandi Chiapelli , Catherine Baublite , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
发明人: Michelle Coutu Hresko , Merry B. McLaird , Deryck J. Williams , Anita M. Frevert , Brandi Chiapelli , Catherine Baublite , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
CPC分类号: C07K14/705
摘要: Nucleic acid molecules from nematodes encoding PAN and ZP domain containing receptor polypeptides are described. PANZP polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PANZP nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
摘要翻译: 描述了编码含有PAN和ZP结构域的受体多肽的线虫的核酸分子。 还提供PANZP多肽序列,载体,宿主细胞以及用于产生PANZP核苷酸和多肽的重组方法。 还描述了用于鉴定抑制剂和/或激活剂的筛选方法以及用于抗体生产的方法。
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公开(公告)号:US07265204B2
公开(公告)日:2007-09-04
申请号:US11191375
申请日:2005-07-28
申请人: Michelle Coutu Hresko , Merry B. McLaird , Deryck J. Williams , Anita M. Frevert , Brandi Chiapelli , Catherine Baublite , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
发明人: Michelle Coutu Hresko , Merry B. McLaird , Deryck J. Williams , Anita M. Frevert , Brandi Chiapelli , Catherine Baublite , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
CPC分类号: C07K14/705
摘要: Nucleic acid molecules from nematodes encoding PAN and ZP domain containing receptor polypeptides are described. PANZP polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PANZP nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
摘要翻译: 描述了编码含有PAN和ZP结构域的受体多肽的线虫的核酸分子。 还提供PANZP多肽序列,载体,宿主细胞以及用于产生PANZP核苷酸和多肽的重组方法。 还描述了用于鉴定抑制剂和/或激活剂的筛选方法以及用于抗体生产的方法。
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公开(公告)号:US20080227955A1
公开(公告)日:2008-09-18
申请号:US12042297
申请日:2008-03-04
申请人: Michelle Coutu Hresko , Merry B. Mclaird , Deryck J. Williams , Anita M. Frevert , Brandi Chiapelli , Catherine Baublite , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
发明人: Michelle Coutu Hresko , Merry B. Mclaird , Deryck J. Williams , Anita M. Frevert , Brandi Chiapelli , Catherine Baublite , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
IPC分类号: C07K14/435
CPC分类号: C07K14/705
摘要: Nucleic acid molecules from nematodes encoding PAN and ZP domain containing receptor polypeptides are described. PANZP polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PANZP nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
摘要翻译: 描述了编码含有PAN和ZP结构域的受体多肽的线虫的核酸分子。 还提供PANZP多肽序列,载体,宿主细胞以及用于产生PANZP核苷酸和多肽的重组方法。 还描述了用于鉴定抑制剂和/或激活剂的筛选方法以及用于抗体生产的方法。
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公开(公告)号:US07250500B2
公开(公告)日:2007-07-31
申请号:US11191374
申请日:2005-07-28
申请人: Michelle Coutu Hresko , Merry B. McLaird , Deryck J. Williams , Anita M. Frevert , Brandi Chiapelli , Catherine Baublite , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
发明人: Michelle Coutu Hresko , Merry B. McLaird , Deryck J. Williams , Anita M. Frevert , Brandi Chiapelli , Catherine Baublite , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
CPC分类号: C07K14/705
摘要: Nucleic acid molecules from nematodes encoding PAN and ZP domain containing receptor polypeptides are described. PANZP polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PANZP nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
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公开(公告)号:US06936693B2
公开(公告)日:2005-08-30
申请号:US10771708
申请日:2004-02-04
申请人: Michelle Coutu Hresko , Merry B. McLaird , Deryck J. Williams , Anita M. Frevert , Brandi Chiapelli , Catherine Baublite , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
发明人: Michelle Coutu Hresko , Merry B. McLaird , Deryck J. Williams , Anita M. Frevert , Brandi Chiapelli , Catherine Baublite , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
IPC分类号: A61K38/17 , C07H21/04 , C07K1/00 , C07K14/00 , C07K14/435 , C07K14/705 , C07K17/00 , C12N20060101 , C12N15/00 , C12P21/06 , C12Q1/68
CPC分类号: C07K14/705
摘要: Nucleic acid molecules from nematodes encoding PAN and ZP domain containing receptor polypeptides are described. PANZP polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PANZP nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
摘要翻译: 描述了编码含有PAN和ZP结构域的受体多肽的线虫的核酸分子。 还提供PANZP多肽序列,载体,宿主细胞以及用于产生PANZP核苷酸和多肽的重组方法。 还描述了用于鉴定抑制剂和/或激活剂的筛选方法以及用于抗体生产的方法。
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公开(公告)号:US20080249160A1
公开(公告)日:2008-10-09
申请号:US12105591
申请日:2008-04-18
申请人: Deryck J. Williams , Andrew P. Kloek , Michelle Coutu Hresko , Barry J. Shortt , Jennifer A. Davila-Aponte , John D. Bradley , James McCarter , Merry B. McLaird
发明人: Deryck J. Williams , Andrew P. Kloek , Michelle Coutu Hresko , Barry J. Shortt , Jennifer A. Davila-Aponte , John D. Bradley , James McCarter , Merry B. McLaird
摘要: Certain fatty acids and related compounds useful in the control nematodes that infest plants or the situs of plants are described. Nematodes that parasitize animals can also be controlled using the methods and compounds of this invention.
摘要翻译: 描述了可用于控制线虫的某些脂肪酸和相关化合物,其侵染植物或植物的部位。 也可以使用本发明的方法和化合物来控制寄生动物的线虫。
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