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公开(公告)号:US20230301563A1
公开(公告)日:2023-09-28
申请号:US18182941
申请日:2023-03-13
Applicant: Dexcom, Inc.
Inventor: Peter C. Simpson , Robert Boock , Paul V Neale , Sebastian Bohm , Matthew D. Wightlin , Jack Pryor , Jason Mitchell , Jeff Jackson , Kaushik Patel , Antonio C. Lievares
IPC: A61B5/1473 , A61B5/1486 , B05C3/12 , B05C3/02 , B23K26/362 , A61B5/145 , B05C3/10
CPC classification number: A61B5/1473 , A61B5/14865 , B05C3/125 , B05C3/02 , B23K26/362 , A61B5/14532 , B05C3/10 , A61B5/1451 , A61B5/14517 , A61B5/14503 , A61B5/14546 , A61B2560/0223 , A61B2562/043 , A61B2562/125 , A61B2562/0209 , B05C5/0241
Abstract: Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor system 800 comprising two working electrodes and at least one reference/counter electrode is provided. The sensor system 800 comprises first and second elongated bodies E1, E2, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layer 810 that separates the conductive layer 820 from the elongated body, a membrane layer deposited on top of the elongated bodies E1, E2, and working electrodes 802′, 802″ formed by removing portions of the conductive layer 820 and the insulating layer 810, thereby exposing electroactive surface of the elongated bodies E1, E2.
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公开(公告)号:US20220346674A1
公开(公告)日:2022-11-03
申请号:US17867608
申请日:2022-07-18
Applicant: DexCom, Inc.
Inventor: Robert Boock , Jeff Jackson , Huashi Zhang , Jason Mitchell
IPC: A61B5/1473 , A61B5/1486 , B05C3/12 , B05C3/02 , A61B5/145 , B05C3/10
Abstract: Described here are embodiments of processes and systems for the continuous manufacturing of implantable continuous analyte sensors. In some embodiments, a method is provided for sequentially advancing an elongated conductive body through a plurality of stations, each configured to treat the elongated conductive body. In some of these embodiments, one or more of the stations is configured to coat the elongated conductive body using a meniscus coating process, whereby a solution formed of a polymer and a solvent is prepared, the solution is continuously circulated to provide a meniscus on a top portion of a vessel holding the solution, and the elongated conductive body is advanced through the meniscus. The method may also comprise the step of removing excess coating material from the elongated conductive body by advancing the elongated conductive body through a die orifice. For example, a provided elongated conductive body 510 is advanced through a pre-coating treatment station 520, through a coating station 530, through a thickness control station 540, through a drying or curing station 550, through a thickness measurement station 560, and through a post-coating treatment station 570.
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公开(公告)号:US09572523B2
公开(公告)日:2017-02-21
申请号:US14861963
申请日:2015-09-22
Applicant: DexCom, Inc.
Inventor: Robert Boock , Monica Rixman Swinney , Huashi Zhang , Michael J. Estes , Kristina Lawrence
IPC: A61B5/1468 , A61B5/1486 , A61B5/145 , G01N27/40 , A61B5/1473 , C12Q1/00 , A61B5/00
CPC classification number: A61B5/14865 , A61B5/14503 , A61B5/14532 , A61B5/14546 , A61B5/1468 , A61B5/1473 , A61B5/1486 , A61B5/72 , A61B5/7475 , B33Y70/00 , C12Q1/006 , G01N27/40
Abstract: Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species.
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公开(公告)号:US09173606B2
公开(公告)日:2015-11-03
申请号:US14169018
申请日:2014-01-30
Applicant: DexCom, Inc.
Inventor: Robert Boock , Monica Rixman Swinney , Huashi Zhang , Michael J. Estes , Kristina Lawrence
IPC: A61B5/145 , G01N27/40 , A61B5/1468 , A61B5/1473 , A61B5/1486 , C12Q1/00
CPC classification number: A61B5/14865 , A61B5/14503 , A61B5/14532 , A61B5/14546 , A61B5/1468 , A61B5/1473 , A61B5/1486 , A61B5/72 , A61B5/7475 , B33Y70/00 , C12Q1/006 , G01N27/40
Abstract: Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species.
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公开(公告)号:US20140123893A1
公开(公告)日:2014-05-08
申请号:US14155814
申请日:2014-01-15
Applicant: DexCom, Inc.
Inventor: Robert Boock , Jeff Jackson , Huashi Zhang , Jason Mitchell
IPC: B05C3/10
Abstract: Described here are embodiments of processes and systems for the continuous manufacturing of implantable continuous analyte sensors. In some embodiments, a method is provided for sequentially advancing an elongated conductive body through a plurality of stations, each configured to treat the elongated conductive body. In some of these embodiments, one or more of the stations is configured to coat the elongated conductive body using a meniscus coating process, whereby a solution formed of a polymer and a solvent is prepared, the solution is continuously circulated to provide a meniscus on a top portion of a vessel holding the solution, and the elongated conductive body is advanced through the meniscus. The method may also comprise the step of removing excess coating material from the elongated conductive body by advancing the elongated conductive body through a die orifice. For example, a provided elongated conductive body 510 is advanced through a pre-coating treatment station 520, through a coating station 530, through a thickness control station 540, through a drying or curing station 550, through a thickness measurement station 560, and through a post-coating treatment station 570.
Abstract translation: 这里描述了用于连续制造可植入的连续分析物传感器的方法和系统的实施方案。 在一些实施例中,提供了一种用于使细长导电体顺序地前进穿过多个台的方法,每个台被构造成处理细长导电体。 在这些实施例中的一些实施例中,一个或多个工位被配置为使用弯液面涂覆工艺涂覆细长导电体,由此制备由聚合物和溶剂形成的溶液,该溶液被连续循环以在 保持溶液的容器的顶部,并且细长导电体前进通过弯液面。 该方法还可以包括通过使细长导电体通过模头孔从细长导电体去除多余涂层材料的步骤。 例如,提供的细长导电体510通过预涂处理站520,穿过涂覆站530,通过厚度控制站540,穿过干燥或固化站550,穿过厚度测量站560,并通过 后涂层处理站570。
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公开(公告)号:US20230165534A1
公开(公告)日:2023-06-01
申请号:US17929576
申请日:2022-09-02
Applicant: Dexcom, Inc.
Inventor: Apurv U. Kamath , Aarthi Mahalingam , Ying Li , Mohammad Shariati , James H. Brauker , Mark C. Brister , Robert Boock
IPC: A61B5/00 , A61B5/145 , A61B5/1486 , A61B5/1495
CPC classification number: A61B5/7203 , A61B5/14532 , A61B5/14539 , A61B5/14865 , A61B5/1495 , A61B5/6848 , A61B5/725 , A61B5/743 , A61B5/7475 , A61B5/01
Abstract: Systems and methods for detecting noise episodes and processing analyte sensor data responsive thereto. In some embodiments, processing analyte sensor data includes filtering the sensor data to reduce or eliminate the effects of the noise episode on the signal.
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公开(公告)号:US20140148667A1
公开(公告)日:2014-05-29
申请号:US14169033
申请日:2014-01-30
Applicant: DexCom, Inc.
Inventor: Robert Boock , Monica Rixman Swinney , Huashi Zhang , Michael J. Estes , Kristina Lawrence
IPC: A61B5/1486
CPC classification number: A61B5/14865 , A61B5/14503 , A61B5/14532 , A61B5/14546 , A61B5/1468 , A61B5/1473 , A61B5/1486 , A61B5/72 , A61B5/7475 , B33Y70/00 , C12Q1/006 , G01N27/40
Abstract: Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species.
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公开(公告)号:US20140148666A1
公开(公告)日:2014-05-29
申请号:US14169018
申请日:2014-01-30
Applicant: DexCom, Inc.
Inventor: Robert Boock , Monica Rixman Swinney , Huashi Zhang , Michael J. Estes , Kristina Lawrence
IPC: A61B5/1486
CPC classification number: A61B5/14865 , A61B5/14503 , A61B5/14532 , A61B5/14546 , A61B5/1468 , A61B5/1473 , A61B5/1486 , A61B5/72 , A61B5/7475 , B33Y70/00 , C12Q1/006 , G01N27/40
Abstract: Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species.
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公开(公告)号:US11730407B2
公开(公告)日:2023-08-22
申请号:US17583057
申请日:2022-01-24
Applicant: Dexcom, Inc.
Inventor: Robert Boock , Monica Rixman Swinney , Huashi Zhang , Michael J. Estes , Kristina Lawrence
IPC: A61B5/1486 , A61B5/1473 , A61B5/1468 , A61B5/145 , G01N27/40 , B33Y70/00 , C12Q1/00 , A61B5/00
CPC classification number: A61B5/14865 , A61B5/1468 , A61B5/1473 , A61B5/1486 , A61B5/14532 , A61B5/14546 , C12Q1/006 , G01N27/40 , A61B5/7203 , B33Y70/00
Abstract: Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species.
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公开(公告)号:US09173607B2
公开(公告)日:2015-11-03
申请号:US14169033
申请日:2014-01-30
Applicant: DexCom, Inc.
Inventor: Robert Boock , Monica Rixman Swinney , Huashi Zhang , Michael J. Estes , Kristina Lawrence
IPC: A61B5/145 , G01N27/40 , A61B5/1468 , A61B5/1473 , A61B5/1486 , C12Q1/00
CPC classification number: A61B5/14865 , A61B5/14503 , A61B5/14532 , A61B5/14546 , A61B5/1468 , A61B5/1473 , A61B5/1486 , A61B5/72 , A61B5/7475 , B33Y70/00 , C12Q1/006 , G01N27/40
Abstract: Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and/or influence of non-constant noise-causing species.
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