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    Mammalian galanin receptors
    4.
    发明授权
    Mammalian galanin receptors 失效
    哺乳动物甘丙肽受体

    公开(公告)号：US07417122B2

    公开(公告)日：2008-08-26

    申请号：US11768449

    申请日：2007-06-26

    申请人： Marvin Bayne ,  Tanaz Hashemi ,  Chaogang He ,  Suke Wang

    发明人： Marvin Bayne ,  Tanaz Hashemi ,  Chaogang He ,  Suke Wang

    IPC分类号： C07K14/00

    CPC分类号： C07K14/72 ,  A61K38/00

    摘要： The present invention provides isolated mammalian GalR3 receptors, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods for making the receptors using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptors and are useful for treating medical conditions caused or mediated by galanin. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian GalR3 receptors.

    摘要翻译： 本发明提供分离的哺乳动物GalR3受体，分离的或重组的核酸和编码其的重组载体，包含核酸和载体的宿主细胞，以及使用宿主细胞制备受体的方法。 本发明进一步提供了与受体特异性结合并可用于治疗由甘丙肽引起或介导的医学病症的抗体及其抗原结合片段。 还提供了用于鉴定哺乳动物GalR3受体的特异性激动剂和拮抗剂的筛选方法。

    Mammalian Galanin receptors
    6.
    发明申请
    Mammalian Galanin receptors 失效
    哺乳动物Galanin受体

    公开(公告)号：US20050026213A1

    公开(公告)日：2005-02-03

    申请号：US10946767

    申请日：2004-09-22

    申请人： Marvin Bayne ,  Tanaz Hashemi ,  Chaogang He ,  Suke Wang

    发明人： Marvin Bayne ,  Tanaz Hashemi ,  Chaogang He ,  Suke Wang

    IPC分类号： A61K38/00 ,  C07K14/72 ,  C12N15/12 ,  C12Q1/68 ,  C07H21/04 ,  G01N33/567

    CPC分类号： C07K14/72 ,  A61K38/00

    摘要： The present invention provides isolated mammalian GalR3 receptors, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods for making the receptors using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptors and are useful for treating medical conditions caused or mediated by galanin. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian GalR3 receptors.

    摘要翻译： 本发明提供分离的哺乳动物GalR3受体，分离的或重组的核酸和编码其的重组载体，包含核酸和载体的宿主细胞，以及使用宿主细胞制备受体的方法。 本发明进一步提供了与受体特异性结合并可用于治疗由甘丙肽引起或介导的医学病症的抗体及其抗原结合片段。 还提供了用于鉴定哺乳动物GalR3受体的特异性激动剂和拮抗剂的筛选方法。

    Mammalian galanin receptors
    7.
    发明授权
    Mammalian galanin receptors 失效
    哺乳动物甘丙肽受体

    公开(公告)号：US07250163B2

    公开(公告)日：2007-07-31

    申请号：US10946767

    申请日：2004-09-22

    申请人： Marvin Bayne ,  Tanaz Hashemi ,  Chaogang He ,  Suke Wang

    发明人： Marvin Bayne ,  Tanaz Hashemi ,  Chaogang He ,  Suke Wang

    IPC分类号： A61K39/395 ,  C07K14/00

    CPC分类号： C07K14/72 ,  A61K38/00

    摘要： The present invention provides isolated mammalian GalR3 receptors, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods for making the receptors using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptors and are useful for treating medical conditions caused or mediated by galanin. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian GalR3 receptors.

    摘要翻译： 本发明提供分离的哺乳动物GalR3受体，分离的或重组的核酸和编码其的重组载体，包含核酸和载体的宿主细胞，以及使用宿主细胞制备受体的方法。 本发明进一步提供了与受体特异性结合并可用于治疗由甘丙肽引起或介导的医学病症的抗体及其抗原结合片段。 还提供了用于鉴定哺乳动物GalR3受体的特异性激动剂和拮抗剂的筛选方法。

    Mammalian galanin receptors
    8.
    发明授权
    Mammalian galanin receptors 失效
    哺乳动物甘丙肽受体

    公开(公告)号：US06693182B1

    公开(公告)日：2004-02-17

    申请号：US08916247

    申请日：1997-08-22

    申请人： Marvin Bayne ,  Tanaz Hashemi ,  Chaogang He ,  Suke Wang

    发明人： Marvin Bayne ,  Tanaz Hashemi ,  Chaogang He ,  Suke Wang

    IPC分类号： C12N1512

    CPC分类号： C07K14/72 ,  A61K38/00

    摘要： The present invention provides isolated mammalian GalR3 receptors, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods for making the receptors using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptors and are useful for treating medical conditions caused or mediated by galanin. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian GalR3 receptors.

    摘要翻译： 本发明提供分离的哺乳动物GalR3受体，分离的或重组的核酸和编码其的重组载体，包含核酸和载体的宿主细胞，以及使用宿主细胞制备受体的方法。 本发明进一步提供了与受体特异性结合并可用于治疗由甘丙肽引起或介导的医学病症的抗体及其抗原结合片段。 还提供了用于鉴定哺乳动物GalR3受体的特异性激动剂和拮抗剂的筛选方法。

    MAMMALIAN GALANIN RECEPTORS
    9.
    发明申请
    MAMMALIAN GALANIN RECEPTORS 失效
    MAMMALIAN GALANIN受体

    公开(公告)号：US20070255044A1

    公开(公告)日：2007-11-01

    申请号：US11768449

    申请日：2007-06-26

    申请人： Marvin Bayne ,  Tanaz Hashemi ,  Chaogang He ,  Suke Wang

    发明人： Marvin Bayne ,  Tanaz Hashemi ,  Chaogang He ,  Suke Wang

    IPC分类号： C07K16/18 ,  C07K14/00

    CPC分类号： C07K14/72 ,  A61K38/00

    摘要： The present invention provides isolated mammalian GalR3 receptors, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods for making the receptors using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptors and are useful for treating medical conditions caused or mediated by galanin. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian GalR3 receptors.

    摘要翻译： 本发明提供分离的哺乳动物GalR3受体，分离的或重组的核酸和编码其的重组载体，包含核酸和载体的宿主细胞，以及使用宿主细胞制备受体的方法。 本发明进一步提供了与受体特异性结合并可用于治疗由甘丙肽引起或介导的医学病症的抗体及其抗原结合片段。 还提供了用于鉴定哺乳动物GalR3受体的特异性激动剂和拮抗剂的筛选方法。