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    Use of Macrolide Derivatives for Treating Acne
    1.
    发明申请
    Use of Macrolide Derivatives for Treating Acne 审中-公开
    使用大环内酯衍生物治疗痤疮

    公开(公告)号：US20090075916A1

    公开(公告)日：2009-03-19

    申请号：US12094645

    申请日：2006-11-22

    申请人： Dilip J. Upadhyay ,  Anjan Chakrabarti ,  Biswajit Das ,  Radhakrishnan Gowrishankar

    发明人： Dilip J. Upadhyay ,  Anjan Chakrabarti ,  Biswajit Das ,  Radhakrishnan Gowrishankar

    IPC分类号： A61K31/7048 ,  A61P17/10

    CPC分类号： A61K31/7056

    摘要： This invention relates to 14-membered macrolide derivatives for treating or preventing acne vulgaris and associated inflammatory conditions. Also provided herein are medicaments or pharmaceutical compositions comprising one or more 14-membered macrolide derivatives together with one or more pharmaceutically acceptable carriers, excipients, diluents or mixture thereof, and methods for treating or preventing acne vulgaris and associated inflammatory conditions.

    摘要翻译： 本发明涉及用于治疗或预防寻常痤疮和相关炎性病症的14-元大环内酯衍生物。 本文还提供包含一种或多种14-元大环内酯衍生物以及一种或多种药学上可接受的载体，赋形剂，稀释剂或其混合物的药物或药物组合物，以及治疗或预防寻常痤疮和相关炎性病症的方法。

    MACROLIDES DERIVATIVES AS ANTIBACTERIAL AGENTS
    2.
    发明申请
    MACROLIDES DERIVATIVES AS ANTIBACTERIAL AGENTS 审中-公开
    抗坏血酸衍生物作为抗菌剂

    公开(公告)号：US20090130225A1

    公开(公告)日：2009-05-21

    申请号：US12094800

    申请日：2006-11-21

    申请人： Anjan Chakrabarti ,  Biswajit Das ,  Jitendra Sambhaji Jadhav ,  Dilip J. Upadhyay

    发明人： Anjan Chakrabarti ,  Biswajit Das ,  Jitendra Sambhaji Jadhav ,  Dilip J. Upadhyay

    IPC分类号： A61K31/7048 ,  C07H17/08 ,  A61K36/28 ,  A61K36/54 ,  A61K33/06 ,  A61K33/24 ,  A61K33/30 ,  A61P3/04 ,  A61P1/00 ,  C07D403/04

    CPC分类号： C07H17/08

    摘要： The present invention provides macrolide derivatives, which can be used as antibacterial agents. Compounds described herein can be used for treating or preventing conditions caused by or contributed to by gram-positive, gram-negative or anaerobic bacteria, more particularly against, for example, Staphylococci, Streptococci, Enterococci, Haemophilus, Moraxalla spp., Chlamydia spp., Mycoplasm, Legionella spp., Mycobacterium, Helicobacter, Clostridium, Bacteroides, Corynebacterium, Propionibeacterium, Bacillus, Enterobactericeae or any combination thereof. Also provided are processes for preparing compounds described herein, pharmaceutical compositions thereof, and methods of treating bacterial infections.

    摘要翻译： 本发明提供可用作抗菌剂的大环内酯衍生物。 本文所述的化合物可用于治疗或预防由革兰氏阳性，革兰氏阴性或厌氧细菌引起或促成的病症，特别是针对例如葡萄球菌，链球菌，肠球菌，嗜血杆菌，马克拉斯氏菌属，衣原体属。 ，支原体属，军团菌属，分枝杆菌属，幽门螺杆菌属，梭菌属，拟杆菌属，棒状杆菌属，丙酸杆菌属，芽孢杆菌属，肠杆菌属或其任何组合。 还提供了制备本文所述化合物的方法，其药物组合物和治疗细菌感染的方法。