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公开(公告)号：US4640821A
公开(公告)日：1987-02-03
申请号：US756149
申请日：1985-07-16
CPC分类号： G01N35/08 , Y10T436/117497
摘要： A system for analyzing a biological fluid or the like includes a series flow loop that extends between an inlet valve array and an outlet valve array. The flow loop includes an analysis region to which a measuring system is connected in sensing relation and an accumulator chamber connected to the outlet of the analysis region. The inlet valve array is arranged to selectively and alternately connect a sample inlet port and an auxiliary fluid reservoir to the flow loop while the outlet valve array is arranged to selectively connect a controlled source of reduced pressure to the flow loop. The volume of the accumulator chamber is at least as great as the volume of the flow loop (including the analysis region) between the inlet valve array and the accumulator chamber and the system is arranged to capture reduced pressure in the flow loop, the captured reduced pressure then being used to provide the sole transfer force to gently and reliably transfer a minute quantity of fluid to be analyzed from the sample inlet port through the analysis region and at least partially fill the accumulator chamber.
摘要翻译： 用于分析生物流体等的系统包括在入口阀阵列和出口阀阵列之间延伸的串联流动回路。 流动回路包括测量系统以感测关系连接的分析区域和连接到分析区域的出口的蓄液室。 入口阀阵列布置成选择性地和交替地将样品入口端口和辅助流体容器连接到流动回路，同时出口阀阵列被布置成选择性地将受控的减压源连接到流动回路。 蓄能器室的容积至少与入口阀阵列和蓄能室之间的流动回路（包括分析区域）的体积一样大，并且系统被设置成在流动回路中捕获减压，所捕获的减少 压力然后被用于提供唯一的转印力，以便将来自待分析的微量流体从样品入口通过分析区域轻轻地和可靠地传递并且至少部分地填充储存室。
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公开(公告)号：US5750906A
公开(公告)日：1998-05-12
申请号：US739249
申请日：1996-10-29
申请人： Norman K. Parker , James E. Rasmussen , Richard L. Schulkind , Kevin J. Sullivan , Robert B. Green
发明人： Norman K. Parker , James E. Rasmussen , Richard L. Schulkind , Kevin J. Sullivan , Robert B. Green
CPC分类号： G01N35/1097
摘要： The invention features a sample probe and reagent selector valve that enables selection among multiple functions of withdrawing a biological sample from a syringe or capillary into a fluid parameter sensor module, providing calibration and quality control reagents to the sensor module, and flowing a washing fluid through intake passages to prevent cross-contamination and clogging. The valve and sensor module are used in conjunction with an automated analytical instrument, such as an automated blood analyzer, to increase the speed of the analysis, minimize cross contamination between samples, and to overcome the inherent dangers of using the conventional needle/syringe or capillary methods of withdrawing fluids to be tested. The design of the valve provides performance benefits in the form of lower sample and reagent waste volumes, elimination of auxiliary valves and manifolds, and superior performance and reduced cost.
摘要翻译： 本发明的特征在于一种样本探针和试剂选择阀，其能够选择将生物样品从注射器或毛细管抽出到流体参数传感器模块中的多种功能，向传感器模块提供校准和质量控制试剂，以及使洗涤液流过 进气通道，以防止交叉污染和堵塞。 阀和传感器模块与诸如自动血液分析仪之类的自动分析仪器一起使用，以提高分析速度，最小化样品之间的交叉污染，并克服使用常规针头/注射器的固有危险 抽出待测试液体的毛细管法。 阀门的设计以较低的样品和试剂废物量，减少辅助阀门和歧管的形式提供了性能优势，并具有出色的性能和降低的成本。
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公开(公告)号：USD521643S1
公开(公告)日：2006-05-23
申请号：US29201619
申请日：2004-03-18
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公开(公告)号：US5492431A
公开(公告)日：1996-02-20
申请号：US203621
申请日：1994-03-01
申请人： James E. Rasmussen , Larry Mosher , James K. Godwin , Larry Swanda , Robert W. Given , Jerry Maynard , Thomas Sidler , Ronald E. Stewart , Richard D. Turnbow
发明人： James E. Rasmussen , Larry Mosher , James K. Godwin , Larry Swanda , Robert W. Given , Jerry Maynard , Thomas Sidler , Ronald E. Stewart , Richard D. Turnbow
CPC分类号： E01C23/0933 , E01C23/04 , E01C2301/50
摘要： An apparatus and method for simultaneously cutting parallel slots in a pavement surface is provided, especially for dowel bar retrofit load transfer restoration at joints. The apparatus includes a movable frame lockable with a brake, plurality of parallel cutting blades rotatably mounted on twin cutting heads on the frame, vertical travel unit for raising and lowering the blades independently or in unison, and horizontal travel units for moving the blades horizontally. One of the twin cutting heads is mounted on each side of the frame, with hydraulic adjusting rams for independently setting the width therebetween. A slurry control system which is mounted on the frame provides the blades with coolant and vacuums up the slurry produced during cutting. The method for simultaneously cutting a plurality of slots includes the steps of positioning the apparatus and blades in the desired location, locking the machine against movement relative the surface, rotating the blades, lowering the blades to cut the pavement to a first depth, moving the blades horizontally to form an elongated cut, repeating this plunging and traversing process until the desired depth of cut is achieved, raising the blades and moving the apparatus. The pavement between the parallel cuts is easily removed by a jack hammer.
摘要翻译： 提供了一种用于同时切割路面中的平行槽的装置和方法，特别是用于接头处的榫钉改造负载传递恢复。 该装置包括可用制动器锁定的可移动框架，可转动地安装在框架上的双切割头上的多个平行切割刀片，用于独立地或一致地升降叶片的垂直行进单元，以及用于水平移动叶片的水平移动单元。 两个切割头中的一个安装在框架的每一侧，具有用于独立设置其间宽度的液压调节柱塞。 安装在框架上的浆料控制系统为叶片提供冷却剂并使切割期间产生的浆料真空。 用于同时切割多个槽的方法包括以下步骤：将设备和叶片定位在期望的位置，使机器相对于表面防止移动，旋转叶片，降低叶片以将路面切割成第一深度， 水平地形成叶片以形成细长的切口，重复该突入和横切过程，直到实现所需的切割深度，提升叶片并移动设备。 平行切口之间的路面很容易通过千斤顶锤除去。
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公开(公告)号：USD376208S
公开(公告)日：1996-12-03
申请号：US29341
申请日：1994-10-03
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6.发明授权
公开(公告)号：US5133937A
公开(公告)日：1992-07-28
申请号：US360008
申请日：1989-06-01
CPC分类号： B01L7/00 , B01L3/502 , G01N33/48 , G01N35/00 , Y10T436/117497
摘要： An analysis system for analyzing a biological fluid or the like for a constituent of the interest includes metal body structure with sample flow path channel structure that serially interconnects heater chamber structure, recess structure for receiving a reaction chamber cartridge and an analysis region to which a measuring system is coupled. The reaction chamber cartridge preferably includes reaction chamber structure with an immobilized enzyme in the reaction chamber that is capable of converting the constituent of interest to a constituent detectable by the measuring system. Cooperating with the metal body structure is a transparent face plate structure which permits visual observation of the sample flow path in the metal body structure. Thermally coupled to the metal body immediately adjacent the analysis region are a temperature sensor that provides a temperature signal to a control unit and a thermal source that receives control signals from the control unit as a function of signals from the temperature system for stabilizing the temperature of the metal body structure (including the reaction chamber structure, the heater chamber and the analysis region) at a desired analysis temperature.
摘要翻译： 用于分析感兴趣的组成部分的生物流体等的分析系统包括金属体结构，其具有将加热器室结构串联连接的样品流路通道结构，用于接收反应室筒的凹部结构和测量 系统耦合。 反应室筒优选地包括在反应室中具有固定化酶的反应室结构，其能够将感兴趣的成分转化成可由测量系统检测的成分。 与金属体结构配合的是透明的面板结构，其可以在金属体结构中对样品流路进行目视观察。 与分析区域紧邻的金属体热耦合是温度传感器，其向控制单元和热源提供温度信号，该温度信号作为温度系统的信号从控制单元接收控制信号，以稳定温度 金属体结构（包括反应室结构，加热室和分析区）。
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公开(公告)号：US06719888B1
公开(公告)日：2004-04-13
申请号：US08921103
申请日：1997-08-29
申请人： Andy D. C. Chan , Joseph S. Foos , James E. Rasmussen , Richard L. Schulkind , John A. Zalenski
发明人： Andy D. C. Chan , Joseph S. Foos , James E. Rasmussen , Richard L. Schulkind , John A. Zalenski
IPC分类号： G01N27401
CPC分类号： G01N27/401 , G01N27/301
摘要： A reference electrode assembly having a constrained-diffusion liquid junction between a liquid junction solution and a sample solution having separate flow paths, said assembly comprising a flow cell having attached thereto a constraint comprising a region of porous material permeable to water and salts; a remote reservoir for holding said liquid junction solution; a means for moving said liquid junction solution from said reservoir to said constraint; and a reference contact region is provided. This unique configuration provides a reference electrode device of the constrained-diffusion liquid junction type useful in pH and/or ion-selective electrode (ISE) potentiometric sensors and is particularly suitable for use in a mini-integrated electrochemical analyzer.
摘要翻译： 一种参考电极组件，其具有在液体接合溶液和具有分离的流动路径的样品溶液之间的约束扩散液体接合点，所述组件包括流动池，所述流动池附着有包含可透过水和盐的多孔材料区域的约束; 用于保持所述液体接合溶液的远程储存器; 用于将所述液体接合溶液从所述储存器移动到所述约束的装置; 并提供参考接触区域。 这种独特的配置提供了用于pH和/或离子选择性电极（ISE）电位传感器的约束扩散液体接合型的参考电极装置，并且特别适用于微型集成电化学分析仪。
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