Abstract:
A photoelectric sensor is adapted for use in specific applications which require the additional attachment of a circular polarizer. A piece of circular polarizer material is general disc-shaped with two planar surfaces and a peripheral circular surface. The outer periphery of the disc-shaped circular polarizer is encapsulated within a generally annular molded rim. The molded rim is provided with a protrusion that is generally circular and extends from one of the generally flat surfaces of the rim material. The protrusion facilitates the attachment of the rim to the operative face of a photoelectric sensor through the process of ultrasonic welding. Advantages achieved by this device include the facilitated attachment of the circular polarizer to a photoelectric sensor, the protection of the outer peripheral edges of the laminations of the circular polarizer and the avoidance of distortions of the circular polarizer during the manufacturing process.
Abstract:
Immunoassay methods and reagents for the specific quantification of thyroxine in a test sample are disclosed employing antibodies prepared with thyroxine derivatives of the formula: ##STR1## wherein P is an immunogenic carrier material and X is a linking moiety. The present invention also describes the synthesis of unique labelled reagent of the formula: ##STR2## wherein Q is a detectable moiety and W is a linking moiety, preferably fluorescein or a fluorescein derivative.
Abstract:
A high temperature resistant flotation core and a high temperature resistant oil containment boom which allows for the in-situ burning of spilled or leaked oil during offshore oil spill cleanup operations are disclosed. The boom can also be used for precautionary fire containment during non-burn oil spill cleanups and can be easily recovered and redeployed.
Abstract:
Disclosed herein are antibody-nanoparticle conjugates that include two or more nanoparticles (such as gold, palladium, platinum, silver, copper, nickel, cobalt, iridium, or an alloy of two or more thereof) directly linked to an antibody or fragment thereof through a metal-thiol bond. Methods of making the antibody-nanoparticle conjugates disclosed herein include reacting an arylphosphine-nanoparticle composite with a reduced antibody to produce an antibody-nanoparticle conjugate. Also disclosed herein are methods for detecting a target molecule in a sample that include using an antibody-nanoparticle conjugate (such as the antibody-nanoparticle conjugates described herein) and kits for detecting target molecules utilizing the methods disclosed herein.
Abstract:
The present invention is directed to a fluorescence polarization immunoassay for determining the phenylacetylglutamine (PAG) content in body fluids, to the various components needed for preparing and carrying out such an assay, and to the methods of making these components. Specifically, tracers, immunogens and antibodies are disclosed, as well as methods for preparing them. The assay is conducted by measuring the degree of polarization of plane polarized light that has been passed through a solution continuing sample, antiserum and tracer.
Abstract:
Methods and kits for measurement of concentration of FK778 in a biological sample by means of an immunoassay, preferably a competitive immunoassay. In one aspect, the method and kit involve the use of (a) an antibody to FK778 conjugated to a label, e.g., an acridinium label, (b) an antibody to FK778 not conjugated to a label, (c) a solid phase containing an antibody to a first hapten, e.g., a fluorescein hapten, and (d) a bihapten comprising a first hapten and FK778 or an analogue of FK778, e.g., a bihapten comprising a fluorescein hapten and a FK778 hapten. In another aspect, the method and kit involve the use of (a) antibody to FK778, (b) a bihapten comprising FK778 or an analogue of FK778 and a first hapten, e.g., a bihapten comprising the fluorescein hapten and the hapten of FK778 or an analogue of FK778, and (c) a pretreatment reagent.
Abstract:
Immunoassay methods and reagents for the specific quantification of thyroxine in a test sample are disclosed employing antibodies prepared with thyroxine derivatives of the formula: ##STR1## wherein P is an immunogenic carrier material and X is a linking moiety. The present invention also describes the synthesis of unique labelled reagent of the formula: ##STR2## wherein Q is a detectable moiety and W is a linking moiety, preferably fluorescein or a fluorescein derivative.
Abstract:
Immunoassay methods and reagents for the specific quantification of thyroxine in a test sample are disclosed employing antibodies prepared with thyroxine derivatives of the formula: ##STR1## wherein P is an immunogenic carrier material and X is a linking moiety. The present invention also describes the synthesis of unique labelled reagent of the formula: ##STR2## wherein Q is a detectable moiety and W is a linking moiety, preferably fluorescein or a fluorescein derivative.
Abstract:
An asynchronous photodetector circuit is provided to interrogate incoming signals and determine whether the frequency of those incoming signal pulses is acceptable. The circuitry of the present invention permits a series of incoming pulses to be interrogated to determine whether the frequency of those pulses is acceptable and can be assumed with confidence to be emanating from an appropriate light source. Upon the receipt of a first input signal pulse, a time window is created by the present invention to define a period to time during which a subsequent input signal pulse is to be expected. Other than during the duration of the time window, the present invention will not accept an input signal pulse and will not count that pulse as having been received. Each properly received pulse creates a subsequent time window until a predetermined number of consecutive pulses is received during their time windows. When that predetermined number is received, a signal is provided. In a particularly preferred embodiment of the present invention, the signal that the predetermined number of consecutive pulses have been received is used to lower the threshold voltage of a comparator for the purpose of facilitating receipt of subsequent signals once the appropriateness of the incoming stream of pulses is determined.