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    System and method for predicting the interaction between proteins based on domain combination
    1.
    发明申请
    System and method for predicting the interaction between proteins based on domain combination 审中-公开
    基于域组合的蛋白质相互作用的系统和方法

    公开(公告)号：US20050044122A1

    公开(公告)日：2005-02-24

    申请号：US10771407

    申请日：2004-02-05

    申请人： Dong-Soo Han ,  Hong-Soog Kim ,  Jung-Min Seo ,  Woo-Hyuk Jang

    发明人： Dong-Soo Han ,  Hong-Soog Kim ,  Jung-Min Seo ,  Woo-Hyuk Jang

    IPC分类号： G01N33/48 ,  G06F17/15 ,  G06F19/00 ,  G06F19/18 ,  G06F19/22

    CPC分类号： G16B5/00 ,  G16B20/00

    摘要： Disclosed are a system and a method for statistically predicting an interaction probability between proteins, and more particularly to a system and a method for predicting an interaction probability between an unknown protein pair based on information obtained by analyzing differences between interacting and non-interacting sets of protein pairs from the view point of domain combination. The prediction method includes the steps of (a) obtaining appearance frequency information of a designated domain combination selected from each of interacting and non-interacting sets of protein pairs, and storing the obtained appearance frequency information, (b) determining a probability equation applied to predict the interaction between two proteins using the stored appearance frequency information of the domain combination, and (c) obtaining an interaction probability value between the two proteins from the determined probability equation.

    摘要翻译： 公开了用于统计预测蛋白质之间的相互作用概率的系统和方法，更具体地涉及一种系统和方法，用于基于通过分析相互作用和非相互作用的组之间的差异而获得的信息来预测未知蛋白质对之间的相互作用概率 从组合角度看蛋白质对。 该预测方法包括以下步骤：（a）从蛋白质对的相互作用和非相互作用的集合中选出的指定结构域组合的出现频度信息，存储所获得的出现频度信息，（b）确定应用于 使用所述域组合的存储的出现频率信息预测两种蛋白质之间的相互作用，以及（c）从确定的概率方程式获得两种蛋白质之间的相互作用概率值。

    Plasmid originated from bifidobacterium, recombinant expression vector using the plasmid and transformation method
    4.
    发明授权
    Plasmid originated from bifidobacterium, recombinant expression vector using the plasmid and transformation method 失效
    质粒源自双歧杆菌，重组表达载体使用质粒和转化方法

    公开(公告)号：US06887702B2

    公开(公告)日：2005-05-03

    申请号：US10258440

    申请日：2001-03-30

    申请人： Geun-Eog Ji ,  Myeong-Soo Park ,  Yun-Hee Kang ,  Jung-Min Seo

    发明人： Geun-Eog Ji ,  Myeong-Soo Park ,  Yun-Hee Kang ,  Jung-Min Seo

    IPC分类号： C12N15/09 ,  C12N1/21 ,  C12N15/70 ,  C12N15/74

    CPC分类号： C12N15/70 ,  C12N15/746

    摘要： The present invention relates to a new plasmid originated from (Bifidobacterium) a recombinant expression vector and transformation method using the same. More particularly, the present invention relates to a plasmid pMG1 having nucleotide sequence represented by SEQ.ID.NO.1; (Bifidobacterium longum) MG1 including the plasmid pMG1; and a shuttle vector which can be replicated in both (Bifidobacterium) and (E. coli), and comprises (Mob) gene having nucleotide sequence represented by SEQ.ID.NO.2. (Rep) gene having nucleotide sequence represented by SEQ.ID.NO.3 and a selection marker. The shuttle vector and the promoter of the present invention can be used for expressing target gene without additional purification process. The protein expressed from the target gene in (Bifidobacterium) can be added to food, therefore, the protein can be used for preparing food additives or oral vaccine, Furthermore, the potential and the possibilty of probiotics using (Bifidobacterium) can promoted through the development of the shuttle vector.

    摘要翻译： 本发明涉及来自（双歧杆菌）的重组表达载体的新质粒和使用其的转化方法。 更具体地，本发明涉及具有由SEQ.ID.NO.1表示的核苷酸序列的质粒pMG1; （双歧杆菌）MG1，包含质粒pMG1; 和可以在（双歧杆菌）和（大肠杆菌）中复制的穿梭载体，并且包含具有由SEQ.ID.NO.2表示的核苷酸序列的（Mob）基因。 （Rep）基因，其具有由SEQ.ID.NO.3表示的核苷酸序列和选择标记。 本发明的穿梭载体和启动子可用于表达靶基因而无需额外的纯化过程。 从双歧杆菌中的目标基因表达的蛋白质可以添加到食品中，因此蛋白质可用于制备食品添加剂或口服疫苗。此外，使用（双歧杆菌）的益生菌的潜力和可能性可以通过开发来促进 的穿梭载体。

    System and method for providing connection between client and heterogeneous database management systems
    7.
    发明授权
    System and method for providing connection between client and heterogeneous database management systems 有权
    提供客户端和异构数据库管理系统之间的连接的系统和方法

    公开(公告)号：US06732360B1

    公开(公告)日：2004-05-04

    申请号：US09455931

    申请日：1999-12-07

    申请人： Jung-Min Seo ,  Ju-Won Song ,  Eun-Sook Jin ,  Su-Young Yoon ,  Moon-Haeng Huh

    发明人： Jung-Min Seo ,  Ju-Won Song ,  Eun-Sook Jin ,  Su-Young Yoon ,  Moon-Haeng Huh

    IPC分类号： G06F15163

    CPC分类号： H04L41/022 ,  H04L41/024

    摘要： A method for providing a connection between a client and heterogeneous database management systems, includes the steps of: a) generating a thread in response to a request message transmitted from the client; b) determining what is the request message and operating a database driver to process the request message by referring to a client information management table; and c) registering identification information of a client and a database in the client information management table and transmitting an execution result corresponding to the request message from the database driver to the client.

    摘要翻译： 一种用于在客户机和异构数据库管理系统之间提供连接的方法，包括以下步骤：a）响应于从客户端发送的请求消息生成线程; b）通过参考客户端信息管理表来确定请求消息是什么和操作数据库驱动程序来处理请求消息; 以及c）将所述客户端和数据库的识别信息登记在所述客户端信息管理表中，并将与所述请求消息对应的执行结果从所述数据库驱动程序发送到所述客户端。