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公开(公告)号：US07792581B2
公开(公告)日：2010-09-07
申请号：US11363729
申请日：2006-02-28
IPC分类号： A61N1/365
CPC分类号： A61N1/3627
摘要： Methods and systems for treating patients with diastolic heart failure (DHF) are disclosed which include slowing a patient's heart rate below its intrinsic rate, and controlling the rate using cardiac pacing therapy to improve LV filling and cardiac output. In certain embodiments, a pacing treatment rate may be determined by adjusting an adaptive rate by an amount determined by evaluating one or more patient parameters.
摘要翻译： 公开了用于治疗舒张性心力衰竭（DHF）患者的方法和系统，其包括将患者的心率降低到其内在速率以下，并且使用心脏起搏治疗来控制速率以改善LV灌注和心输出量。 在某些实施例中，起搏治疗率可以通过将自适应速率调整到通过评估一个或多个患者参数确定的量来确定。
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公开(公告)号：US09375578B2
公开(公告)日：2016-06-28
申请号：US12178534
申请日：2008-07-23
IPC分类号： A61N1/368
CPC分类号： A61N1/368 , A61N1/3682
摘要： A method and apparatus is provided for determining whether a current atrial-ventricular (AV) delay during cardiac pacing is appropriate for proper mechanical coupling of the atrium and ventricle. If proper mechanical coupling is determined to not exist, an additional atrial contraction is induced within the same ventricular cycle to maintain atrial-ventricular mechanical coupling.
摘要翻译： 提供了一种用于确定心脏起搏期间当前心房（AV）延迟是否适合于心房和心室的适当机械耦合的方法和装置。 如果确定不存在适当的机械耦合，则在相同心室周期内诱发另外的心房收缩以维持心房 - 心室机械耦合。
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3.发明授权System and method for using atrial pacing to enhance function of stunned atrial myocardium following conversion to normal sinus rhythm 有权使用心房起搏来改善正常窦性心律后震颤心房心肌功能的系统和方法公开(公告)号：US08700155B2
公开(公告)日：2014-04-15
申请号：US11095846
申请日：2005-03-31
IPC分类号： A61N1/365
CPC分类号： A61N1/3622 , A61B5/046 , A61N1/3627 , A61N1/36514 , A61N1/36557 , A61N1/36564 , A61N1/3962
摘要： An implantable medical device (IMD) having a therapy circuit for delivering atrial pacing and a control circuit for detecting a return to sinus rhythm. The control circuit determines the duration of an atrial arrhythmia preceding the return to sinus rhythm, and controls the therapy circuit to deliver transient atrial pacing based on the atrial arrhythmia duration.
摘要翻译： 一种具有用于递送心房起搏的治疗电路和用于检测回到窦性心律的控制电路的可植入医疗装置（IMD）。 控制电路确定返回到窦性心律之前的心房心律失常的持续时间，并且控制治疗电路基于心房心律失常持续时间递送瞬时心房起搏。
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4.发明授权Control of atrial defibrillation therapy based on hemodynamic sensor feedback 有权基于血流动力学传感器反馈控制心房除颤治疗公开(公告)号：US07336994B2
公开(公告)日：2008-02-26
申请号：US10760155
申请日：2004-01-16
申请人： Douglas A. Hettrick , David E. Euler , Eduardo N. Warman , Michael R. Ujhelyi , Rahul Mehra , Paul D. Ziegler , Shailesh Kumar V. Musley , Charles E. Distad , David E. Ritscher
发明人： Douglas A. Hettrick , David E. Euler , Eduardo N. Warman , Michael R. Ujhelyi , Rahul Mehra , Paul D. Ziegler , Shailesh Kumar V. Musley , Charles E. Distad , David E. Ritscher
IPC分类号： A61N1/39
CPC分类号： A61N1/3702 , A61N1/3621 , A61N1/365 , A61N1/36564 , A61N1/395 , A61N1/3962
摘要： Control of defibrillation therapy delivered by implantable medical devices (IMDs) using hemodynamic sensor feedback is disclosed. The hemodynamic sensor feedback allows for increased control over application of atrial defibrillation therapy. Specifically, the therapy is delivered when a fibrillation episode results in a discrete loss of hemodynamic function. Defibrillation therapy is thus withheld for hemodynamically benign arrhythmias.
摘要翻译： 公开了使用血液动力学传感器反馈控制由可植入医疗装置（IMD）递送的除颤疗法。 血液动力学传感器反馈允许增加对心房除颤治疗的应用的控制。 具体来说，当纤维性颤动发作导致血液动力学功能的离散损失时，进行治疗。 因此，对于血液动力学良性心律失常，禁止使用除颤疗法。
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5.发明授权Method and apparatus for evaluating ventricular performance during isovolumic contraction 有权在等容收缩期间评估心室性能的方法和装置公开(公告)号：US07233821B2
公开(公告)日：2007-06-19
申请号：US11097706
申请日：2005-03-31
CPC分类号： A61N1/3627 , A61B8/0858 , A61N1/36528 , A61N1/3684
摘要： A method of evaluating ventricular performance of a heart employing sensors to measure a ventricular dimension signal and deriving indices of ventricular performance therefrom. Premature Shortening (PS) and Isovolumic Lengthening (IL) comprise two indices of ventricular performance determined from analysis of the left ventricular dimension signal during the transition from ventricular filling to ventricular ejection. Measured values of PS and IL are compared to other measured values or reference values to determine if ventricular performance has improved (or worsened). In some embodiments, the dimension sensors may comprise piezoelectric sonomicrometer crystals that operate as ultrasound transmitters and receivers. The sensors may be mounted in relation to a ventricle of the heart either temporarily or permanently, and may be configured either separately from or integrally with cardiac pacing leads.
摘要翻译： 评估使用传感器测量心室尺寸信号并从其导出心室性能指数的心脏心室性能的方法。 过早缩短（PS）和等压延长（IL）包括从心室充填到心室射血的过渡期间从左心室尺寸信号的分析确定的两个心室指数指数。 将PS和IL的测量值与其他测量值或参考值进行比较，以确定心室性能是否改善（或恶化）。 在一些实施例中，尺寸传感器可以包括作为超声波发射器和接收器操作的压电经济测量晶体。 传感器可以相对于心脏的心室临时或永久地安装，并且可以与心脏起搏引线分开地或与心脏起搏引线一体地配置。
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公开(公告)号：US20100023079A1
公开(公告)日：2010-01-28
申请号：US12178534
申请日：2008-07-23
IPC分类号： A61N1/368
CPC分类号： A61N1/368 , A61N1/3682
摘要： A method and apparatus is provided for determining whether a current atrial-ventricular (AV) delay during cardiac pacing is appropriate for proper mechanical coupling of the atrium and ventricle. If proper mechanical coupling is determined to not exist, an additional atrial contraction is induced within the same ventricular cycle to maintain atrial-ventricular mechanical coupling.
摘要翻译： 提供了一种用于确定心脏起搏期间当前心房（AV）延迟是否适合于心房和心室的适当机械耦合的方法和装置。 如果确定不存在适当的机械耦合，则在相同心室周期内诱发另外的心房收缩以维持心房 - 心室机械耦合。
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7.发明授权Combination of electrogram and intra-cardiac pressure to discriminate between fibrillation and tachycardia 有权电图和心脏内压力的组合来区分原纤维性颤动和心动过速公开(公告)号：US07233822B2
公开(公告)日：2007-06-19
申请号：US10881541
申请日：2004-06-29
IPC分类号： A61B5/04
CPC分类号： A61B5/6882 , A61B5/0031 , A61B5/0215 , A61B5/0422 , A61B5/046 , A61B5/0464 , A61B5/7257 , A61B5/7264 , A61N1/3622 , A61N1/36564 , A61N1/3956
摘要： A system and method for detecting and classifying cardiac arrhythmias based on cardiac pressure signals or the combination of cardiac electrical and cardiac pressure signals. A cardiac electrogram signal is sensed to derive a cardiac rate from which an arrhythmia detection is made when the cardiac rate meets arrhythmia detection criteria. An intracardiac pressure signal is sensed to derive an indicator of tachycardia based on an analysis of the pressure signal in either the time domain or frequency domain. The detected arrhythmia is classified as tachycardia or fibrillation based on the tachycardia indicator wherein the tachycardia indicator is compared to tachycardia detection criteria and the arrhythmia is classified as tachycardia if tachycardia detection criteria are met and the arrhythmia is classified as fibrillation if the tachycardia detection criteria are not met.
摘要翻译： 一种基于心脏压力信号或心脏电压和心脏压力信号的组合来检测和分类心律失常的系统和方法。 感测到心电图信号以导出当心率达到心律失常检测标准时进行心律失常检测的心率。 基于对时域或频域中的压力信号的分析，感测心内压力信号以导出心动过速的指标。 检测到的心律失常根据心动过速指标分类为心动过速指标，其中心动过速指标与心动过速检测标准进行比较，如果心动过速检测标准得到满足，则将心律不齐分类为心动过速，如果心动过速检测标准为 没见过。
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公开(公告)号：US08369946B2
公开(公告)日：2013-02-05
申请号：US12211254
申请日：2008-09-16
IPC分类号： A61N1/365
CPC分类号： A61N1/3622 , A61B5/0215 , A61B5/0464 , A61B5/11 , A61B5/145 , A61B5/7264 , A61N1/3624 , A61N1/3962
摘要： An implantable medical device and associated method classify therapy outcomes and heart rhythms in association with therapy outcome. A therapy success time interval is started in response to delivering an arrhythmia therapy. If normal sinus rhythm is detected after the therapy success time interval expires, the delivered therapy is classified as unsuccessful and the detected arrhythmia is classified as a self-terminating rhythm.
摘要翻译： 可植入医疗器械和相关方法将治疗结果和心律相结合的治疗结果进行分类。 响应于递送心律失常疗法开始治疗成功时间间隔。 如果治疗成功时间间隔到期后检测到正常的窦性心律，则将所传递的治疗分类为不成功，并将检测到的心律失常归类为自终止节律。
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9.发明授权公开(公告)号：US08290588B2
公开(公告)日：2012-10-16
申请号：US12722959
申请日：2010-03-12
CPC分类号： A61N1/3622
摘要： With a method and apparatus for detecting cardiac arrhythmias during overdrive pacing, a maximum paced rate and a reduced paced rate for a heart are determined, the maximum paced rate being higher than the reduced paced rate. The heart is paced at the maximum paced rate. After the heart is paced at the maximum paced rate for a predetermined amount of time, the heart is paced at the reduced paced rate.
摘要翻译： 利用用于在超速起搏期间检测心律不齐的方法和装置，确定心脏的最大起搏速率和降低的起搏速率，最大起搏速率高于降低的起搏速率。 心脏以最高的起搏速度起搏。 心脏以最大的起搏速度起搏一段预定的时间后，心脏以降低的起搏速度起搏。
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公开(公告)号：US20120109245A1
公开(公告)日：2012-05-03
申请号：US12916012
申请日：2010-10-29
IPC分类号： A61N1/365
CPC分类号： A61N1/36521 , A61B5/0452 , A61B5/0535 , A61B5/7239 , A61N1/3627 , A61N1/3682 , A61N1/3684 , A61N1/3987
摘要： Methods and/or devices are disclosed herein for monitoring cardiac impedance signal and delivering therapy to a patient's heart based upon the monitored cardiac impedance.
摘要翻译： 本文公开了用于监测心脏阻抗信号并基于所监测的心脏阻抗将治疗递送到患者心脏的方法和/或装置。
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