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公开(公告)号：US11759317B2
公开(公告)日：2023-09-19
申请号：US17071641
申请日：2020-10-15
Applicant: Edwards Lifesciences Corporation
Inventor： Son V. Nguyen , Kevin D. Rupp , Ajay Chadha , Jeff Lindstrom
IPC: A61F2/24 , D03D3/02 , D03D25/00 , D03D15/283
CPC classification number: A61F2/2409 , D03D3/02 , D03D15/283 , D03D25/005 , A61F2/2418 , A61F2210/0019 , A61F2210/0071 , A61F2210/0076 , A61F2220/0075 , A61F2230/0069 , A61F2240/004 , A61F2250/006 , A61F2250/0069 , D10B2509/00
Abstract: A docking device includes a hollow cylindrical body portion having an internal surface and an outer surface. The hollow cylindrical body portion is formed of a three-dimensional (3D) woven fabric comprising a plurality of different types of fibers.
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公开(公告)号：US20180168804A1
公开(公告)日：2018-06-21
申请号：US15841046
申请日：2017-12-13
Applicant: Edwards Lifesciences Corporation
Inventor： Son V. Nguyen , Kevin D. Rupp , Ajay Chadha , Jeff Lindstrom
Abstract: A docking device for a bioprosthesis is disclosed that can change shape and recover after a deforming stress is removed, that adjusts to surrounding conditions to accommodate different complex anatomic geometries, and that mitigates leakage around the bioprosthesis. The docking device can include a 3D woven fabric forming an internal surface, an outer surface, and a thickness therebetween. A filler can be coupled to the outer surface. A method for making a docking device is also provided. The method includes weaving a 3D woven fabric by interlacing a shape memory material, a low-melt thermoplastic polymer or resin having a melting point, and a high-tenacity biocompatible material; and pressing and heating the 3D woven fabric over a shape-setting mold at temperatures greater than the melting point of the low-melt thermoplastic polymer or resin.
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公开(公告)号：US11298889B2
公开(公告)日：2022-04-12
申请号：US16294761
申请日：2019-03-06
Applicant: Edwards Lifesciences Corporation
Inventor： Itai Pelled , Elena Sherman , Eran Goldberg , Kevin D. Rupp , Noam Nir
Abstract: An implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration comprises an annular frame having an inflow end and an outflow end, a leaflet structure positioned within the frame and secured thereto, and a laminate sealing member comprising an encapsulating material. The laminate sealing member has a main portion that encapsulates at least a portion of the frame and an end portion extending from the inflow end of the frame, and the end portion of the laminate sealing member is folded to form a cuff adjacent the inflow end of the frame and secured to the main portion of the laminate sealing member.
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公开(公告)号：US10588744B2
公开(公告)日：2020-03-17
申请号：US15252110
申请日：2016-08-30
Applicant: Edwards Lifesciences Corporation
Inventor： Kevin D. Rupp , Tung T. Le , Thanh Huy Le , Brian C. Gray , Alejandro J. Froimovich Rosenberg , Jeff Lindstrom , Kim D. Nguyen , Sonny Tran
Abstract: A delivery apparatus for implanting a radially compressible and expandable prosthetic heart valve in a native heart valve of the heart includes a handle portion and an elongated shaft extending from and movable relative to the handle portion. The shaft includes a proximal end portion coupled to the handle portion and a distal end portion configured to mount a prosthetic heart valve in a radially compressed state. The handle portion includes a control member movable longitudinally with respect to the handle portion, the control member engaging a gear assembly operable to convert longitudinal motion of the control member to rotational motion of the gear assembly. The gear assembly engages the elongated shaft such that rotational motion of the gear assembly causes corresponding longitudinal motion of the elongated shaft relative to the handle portion.
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公开(公告)号：US20190159895A1
公开(公告)日：2019-05-30
申请号：US16262188
申请日：2019-01-30
Applicant: Edwards Lifesciences Corporation
Inventor： Tamir S. Levi , Ron Sharoni , Elena Sherman , Oren H. Wintner , Kevin D. Rupp , Son V. Nguyen , Ajay Chadha , Jeff Lindstrom
IPC: A61F2/24
Abstract: Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. The prosthetic valve can comprise an annular frame, leaflets, an inner skirt, and an outer skirt. The outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack that buckles outward radially when the valve is in the expanded configuration and which lies flat when the valve is in the collapsed configuration. In some embodiments, the outer skirt is stiffer in the axial direction of the valve than in the circumferential direction of the valve. In additional embodiments, the outer skirt comprises a self-expandable fabric comprising fibers made of a shape memory material having a shape memory set to enhance the radially outward buckling of the outer skirt. Methods of crimping such valves to a collapsed or partially collapsed configuration are also disclosed.
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Patent Agency Ranking
公开(公告)号：US10232564B2
公开(公告)日：2019-03-19
申请号：US15140387
申请日：2016-04-27
Applicant: Edwards Lifesciences Corporation
Inventor： Itai Pelled , Elena Sherman , Eran Goldberg , Kevin D. Rupp , Noam Nir
Abstract: The present disclosure relates to laminated sealing members for prosthetic valves and methods of making the same. In a representative embodiment, an implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration comprises an annular frame having an inflow end and an outflow end, a leaflet structure positioned within the frame and secured thereto, and a laminate sealing member comprising an encapsulating material. The laminate sealing member has a main portion that encapsulates at least a portion of the frame and an end portion extending from the inflow end of the frame, and the end portion of the laminate sealing member is folded to form a cuff adjacent the inflow end of the frame and secured to the main portion of the laminate sealing member.
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公开(公告)号：US20150320556A1
公开(公告)日：2015-11-12
申请号：US14704861
申请日：2015-05-05
Applicant: Edwards Lifesciences Corporation
Inventor： Tamir S. Levi , Ron Sharoni , Elena Sherman , Oren H. Wintner , Kevin D. Rupp , Son V. Nguyen , Ajay Chadha , Jeff Lindstrom
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2002/9522 , A61F2220/0025 , A61F2220/0075 , A61F2230/0054 , A61F2250/0018 , A61F2250/0039 , A61F2250/0069 , Y10T29/49927
Abstract: Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. The prosthetic valve can comprise an annular frame, leaflets, an inner skirt, and an outer skirt. The outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack that buckles outward radially when the valve is in the expanded configuration and which lies flat when the valve is in the collapsed configuration. In some embodiments, the outer skirt is stiffer in the axial direction of the valve than in the circumferential direction of the valve. In additional embodiments, the outer skirt comprises a self-expandable fabric comprising fibers made of a shape memory material having a shape memory set to enhance the radially outward buckling of the outer skirt. Methods of crimping such valves to a collapsed or partially collapsed configuration are also disclosed.
Abstract translation: 公开了径向可折叠和可扩张的假体心脏瓣膜的实施例。 假体瓣膜可包括环形框架，小叶，内裙部和外裙部。 外裙部可以固定到框架的流入端部分的外部，外裙部具有纵向松弛，当阀处于膨胀构型时在径向向外弯曲，并且当阀处于折叠构型时它处于平坦状态。 在一些实施例中，外裙部在阀的轴向方向上比阀的圆周方向更硬。 在另外的实施例中，外裙部包括自膨胀织物，其包括由形状记忆材料制成的纤维，该形状记忆材料具有设置成增强外裙部径向向外屈曲的形状记忆。 还公开了将这种阀压接成折叠或部分收缩的构造的方法。
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公开(公告)号：US20240115375A1
公开(公告)日：2024-04-11
申请号：US18542482
申请日：2023-12-15
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Lien Huong Thi Hoang , Son V. Nguyen , Hien Tran Ngo , Vivian Tran , Russell T. Joseph , Dinesh L. Sirimanne , Kevin D. Rupp , Diana Nguyen-Thien-Nhon
IPC: A61F2/24
CPC classification number: A61F2/2409 , A61F2/2418 , A61F2230/0006 , A61F2230/0069 , A61F2230/0076
Abstract: A prosthetic heart valve includes an annular frame that is radially collapsible and expandable between a radially collapsed configuration and a radially expanded configuration. The frame has a plurality of circumferentially extending rows of angled struts, each row of angled struts comprising angled struts arranged in a zig-zag pattern. The prosthetic heart valve further includes a leaflet structure positioned within the frame and secured thereto, and an outer sealing member mounted outside of the frame. The sealing member has an undulating outflow edge portion forming a plurality of triangular projections that are connected to and shaped to correspond to the zig-zag pattern of one of the rows of angled struts. The outer sealing member is sized to fit snugly against the outer surface of the frame when the frame is in the expanded configuration.
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公开(公告)号：US11883281B2
公开(公告)日：2024-01-30
申请号：US17708428
申请日：2022-03-30
Applicant: Edwards Lifesciences Corporation
Inventor： Lien Huong Thi Hoang , Son V. Nguyen , Hien Tran Ngo , Vivian Tran , Russell T. Joseph , Dinesh L. Sirimanne , Kevin D. Rupp , Diana Nguyen-Thien-Nhon
IPC: A61F2/24
CPC classification number: A61F2/2409 , A61F2/2418 , A61F2230/0006 , A61F2230/0069 , A61F2230/0076
Abstract: A prosthetic heart valve includes an annular frame that has an inflow end and an outflow end and is radially compressible and expandable between a radially compressed configuration and a radially expanded configuration. The prosthetic heart valve further includes a leaflet structure positioned within the frame and secured thereto, and an outer sealing member mounted outside of the frame and adapted to seal against surrounding tissue when the prosthetic heart valve is implanted within a native heart valve annulus of a patient. The sealing member can include a mesh layer and pile layer comprising a plurality of pile yarns extending outwardly from the mesh layer.
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公开(公告)号：US11103345B2
公开(公告)日：2021-08-31
申请号：US16262188
申请日：2019-01-30
Applicant: Edwards Lifesciences Corporation
Inventor： Tamir S. Levi , Ron Sharoni , Elena Sherman , Oren H. Wintner , Kevin D. Rupp , Son V. Nguyen , Ajay Chadha , Jeff Lindstrom
Abstract: Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. The prosthetic valve can comprise an annular frame, leaflets, an inner skirt, and an outer skirt. The outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack that buckles outward radially when the valve is in the expanded configuration and which lies flat when the valve is in the collapsed configuration. In some embodiments, the outer skirt is stiffer in the axial direction of the valve than in the circumferential direction of the valve. In additional embodiments, the outer skirt comprises a self-expandable fabric comprising fibers made of a shape memory material having a shape memory set to enhance the radially outward buckling of the outer skirt. Methods of crimping such valves to a collapsed or partially collapsed configuration are also disclosed.
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