公开(公告)号：US20250134656A1

公开(公告)日：2025-05-01

申请号：US19008936

申请日：2025-01-03

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Noam Nir ,  Michael Bukin

IPC: A61F2/24 ,  A61F2/95

Abstract: In some embodiments, a prosthetic valve assembly includes an annular frame being radially expandable and compressible between a radially compressed configuration and a radially expanded configuration, and a valvular structure comprising a plurality of leaflets mounted inside the annular frame. The annular frame includes a plurality of posts. Each post has a pair of commissure attachment members extending away from the post. Each pair of commissure tabs is attached to a corresponding pair of the commissure attachment members.

公开(公告)号：US20250099239A1

公开(公告)日：2025-03-27

申请号：US18969878

申请日：2024-12-05

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Anatoly Dvorsky ,  Eran Grosu ,  Ilan Leshecz ,  Michael Bukin ,  Nikolai Gurovich ,  Assaf Sharon ,  David Maimon

IPC: A61F2/24

Abstract: Prosthetic valves that include support arms extending from support posts thereof, and methods for utilizing such prosthetic valves, are disclosed herein. As one example, a prosthetic valve can include an annular frame movable between a radially compressed state and a radially expanded state, and at least one support arm. The frame can include a plurality of support posts, each extending between a post inflow end and an opposite post outflow end. The support arm can extend from a corresponding support post, and terminate at a free-ended tip which is biased radially away from the corresponding support post.

公开(公告)号：US20240277473A1

公开(公告)日：2024-08-22

申请号：US18645284

申请日：2024-04-24

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Michael Bukin ,  Nikolai Gurovich ,  Anatoly Dvorsky ,  Eran Grosu ,  Noam Nir ,  Joseph Mordechai Leichner

IPC: A61F2/24

CPC classification number: A61F2/243 ,  A61F2/2418 ,  A61F2250/001

Abstract: A prosthetic device, such as a prosthetic heart valve, can include a radially compressible and expandable frame and a screw actuator that is coupled to the frame and configured to be rotated to radially expand the frame from a radially compressed state to a first radially expanded state. The frame includes an over-expansion structure that is configured to allow relative sliding movement between the screw actuator and the frame in a longitudinal direction to permit the frame to radially expand from the first radially expanded state to a second radially expanded state when an external expansion force applied to the prosthetic heart valve exceeds a predetermined force.

公开(公告)号：US12053601B2

公开(公告)日：2024-08-06

申请号：US17111924

申请日：2020-12-04

Applicant: Edwards Lifesciences Corporation

Inventor： Tomer Saar ,  Michael Bukin ,  Dudu Haimovich ,  Roee Haimovich ,  Ohad Yakobovitch

IPC: A61M39/22 ,  A61F2/24 ,  A61M25/10 ,  A61F2/958 ,  A61M5/31 ,  A61M5/315

CPC classification number: A61M25/10182 ,  A61F2/2433 ,  A61M25/10186 ,  A61M39/22 ,  A61F2/958 ,  A61M2005/3128 ,  A61M2005/31598

Abstract: Disclosed herein are inflators and methods of using the inflators for inflating inflatable devices, such as balloons, used in medical procedures. Such procedures include angioplasty and the transcatheter delivery of prosthetic heart valves and stents. The inflators overcome the resistances typically generated during such procedures and reduces the force required to fully inflate the balloon.

公开(公告)号：US20230240840A1

公开(公告)日：2023-08-03

申请号：US18130841

申请日：2023-04-04

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Nadav Ben Zaken ,  Michael Bukin ,  Abdorruhman M. Yousef ,  Sandip Vasant Pawar ,  Assaf Bash

IPC: A61F2/24

CPC classification number: A61F2/24 ,  A61F2220/0025 ,  A61F2250/001

Abstract: The present invention relates to implantable prosthetic devices, such as prosthetic heart valves, provided with a plurality of protective covers over various components of the frame or commissural support members of the valves.

公开(公告)号：US20230051890A1

公开(公告)日：2023-02-16

申请号：US17978826

申请日：2022-11-01

Applicant: Edwards Lifesciences Corporation

Inventor： Noam Nir ,  Michael Bukin

IPC: A61F2/24

Abstract: A buckle commissure clamp can be used to attach leaflets of a valvular structure to a frame of a prosthetic heart valve. Tabs of adjacent leaflets can be assembled to the buckle commissure clamp by passing each leaflet through one or more gaps of the buckle commissure clamp. Each leaflet tab can be wrapped around portions of the buckle commissure clamp. Once the leaflet tabs are assembled to the buckle commissure clamp, the assembly can be attached to the frame, for example, by one or more sutures extending between the buckle commissure clamp and a support member, such as a strut of the frame, an actuator of the frame, a locking mechanism of the frame. In some embodiments, the buckle commissure clamp has a substantially W-shape or M-shape.

公开(公告)号：US20220409366A1

公开(公告)日：2022-12-29

申请号：US17901602

申请日：2022-09-01

Applicant: Edwards Lifesciences Corporation

Inventor： Michael Bukin ,  Noam Nir ,  Tamir S. Levi ,  Ziv Yohanan ,  Elena Sherman ,  Eran Goldberg ,  David Maimon

IPC: A61F2/24

Abstract: A prosthetic heart valve and associated methods for assembling a prosthetic heart valve including a plurality of leaflets is disclosed. As one example, a prosthetic heart valve includes a frame; a plurality of commissure support elements, each connected the frame and including two axially-extending members spaced apart from one another to form a window; and a plurality of leaflets, each leaflet comprising a body and two opposing commissure tabs, each commissure tab arranged adjacent to another commissure tab to form a pair of commissure tabs that are disposed in a commissure support element to form a commissure. Each commissure tab includes a series of overlapping layers that include a first set of two overlapping layers that extends through the window and a second set of two overlapping layers that extends away from the first set of two overlapping layers and over an outer side of a corresponding axially-extending member.

公开(公告)号：US20220257367A1

公开(公告)日：2022-08-18

申请号：US17732985

申请日：2022-04-29

Applicant: Edwards Lifesciences Corporation

Inventor： Yair A. Neumann ,  Oren Cohen ,  Khen Perlmutter ,  Eitan Atias ,  Noam Miller ,  Eran Goldberg ,  Anatoly Dvorsky ,  Tamir S. Levi ,  Haim Yushtein ,  Danny M. Garmahi ,  Ziv Yohanan ,  Michael Bukin ,  Noam Nir ,  Elena Sherman ,  Gideon Sagi

IPC: A61F2/24

Abstract: An implantable prosthetic valve can include a frame movable between a radially compressed and a radially expanded configuration. The frame can include a first strut having a first locking feature disposed on a radially facing inner surface of the strut and a second strut having a second locking feature disposed on a radially facing outer surface of the strut. The first and second locking features can engage each other so as to allow pivoting of the first and second struts relative to one another in a first direction upon radial expansion of the frame and resist pivoting of the first and second struts relative to one another in a second direction to resist radial compression of the frame.

公开(公告)号：US20220233305A1

公开(公告)日：2022-07-28

申请号：US17658584

申请日：2022-04-08

Applicant: Edwards Lifesciences Corporation

Inventor： Ziv Yohanan ,  Tamir S. Levi ,  Netanel Benichou ,  Michael Bukin ,  Nikolay Gurovich ,  Elena Sherman

IPC: A61F2/24

Abstract: A method of implanting a prosthetic heart valve within a patient can comprise inserting a distal end portion of a delivery apparatus and a prosthetic heart valve into the patient and advancing the prosthetic heart valve to a deployment location within the heart of the patient and inflating one or more of a plurality of differently-sized balloons in a balloon-assembly on the distal end portion of the delivery apparatus. The prosthetic heart valve can be mounted on the balloon assembly in a crimped state and the inflating of the one or more of the plurality of differently-sized balloons can expand the prosthetic heart valve from the crimped state to a radially expanded state having a non-cylindrical shape.

公开(公告)号：US20220160507A1

公开(公告)日：2022-05-26

申请号：US17670290

申请日：2022-02-11

Applicant: Edwards Lifesciences Corporation

Inventor： Nikolay Gurovich ,  Michael Bukin ,  Elena Sherman ,  Alexey Tsypenyuk

IPC: A61F2/24

Abstract: A prosthetic heart valve and delivery device for delivering the prosthetic heart valve to a target implantation site, which reduce contact between the prosthetic heart valve and a delivery sheath through which the delivery device is advanced to the target implantation site, is disclosed. As one example, a prosthetic heart valve may comprise a frame including a first end with a plurality of apices spaced apart from one another around a circumference of the first end and a cover element covering the plurality of apices. The cover element may include a cushioning element or a bio-resorbable element.