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公开(公告)号:US10675836B2
公开(公告)日:2020-06-09
申请号:US16352966
申请日:2019-03-14
Applicant: EMD Millipore Corporation
Inventor: David DeCoste , Joseph Cianciolo , Michael Furbush , John Saragosa
IPC: B32B5/02 , B32B27/08 , B32B27/12 , B32B27/32 , B32B27/34 , B32B27/40 , B01L3/00 , B65D65/40 , B65D75/58 , G01M3/32
Abstract: A biocontainer film enhanced with an abrasion resistant or “cut-proof” substrate. Such substrates can be combined with current biocontainer materials, via various techniques of embedding, coextrusion or laminating, to maintain the cleanliness and low extractables already validated for biotech manufacturing. The substrate of choice may be constructed from materials known to be more resistant to abrasion and sharp razor type cuts or from materials oriented in such a way to prevent puncture to occur. The new substrate must also be flexible to allow for typical folding as demonstrated by current packaging practices. The new substrate may be constructed from materials other than polymers such as metal, glass or carbon or in combination with polymers. A non-constrained pressure test is also disclosed.
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公开(公告)号:US10138023B2
公开(公告)日:2018-11-27
申请号:US15860146
申请日:2018-01-02
Applicant: EMD Millipore Corporation
Inventor: Aaron Burke , David DeCoste
Abstract: The present invention provides a process for incorporating a wireless device into a plastic container as part of the steps of manufacturing the container. The plastic container can be a flexible plastic bag and are formed of one or more sheets, generally two or more sheets of plastic film or a rigid plastic container such as a tub or tote. The bags are formed by sealing together adjacent edge portions of each film layer. One embodiment of the present invention is to incorporate a wireless device between the edge portions of the film(s) before or during sealing so that the wireless device becomes permanently sealed into the film material but is isolated from both the bag interior and the outside environment. Another embodiment is to incorporate the wireless device onto or into a plastic component that is sealed to the container, such as a nipple or port, so that the wireless device becomes permanently sealed to the container but is isolated from both the container interior and the outside environment.
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公开(公告)号:US20220323300A1
公开(公告)日:2022-10-13
申请号:US17639973
申请日:2020-09-09
Applicant: James DEE , George GAGNE , Daniel LAMOTHE , EMD Millipore Corporation
Inventor: Shannon Cleveland , Marina Varlamova , John Saragosa , David DeCoste , Benjamin Cacace , Daniel Lamothe , George Gagne , James Dee , Wilson Moya , Stefano Berti Perez
Abstract: A biocontainer having a first film, the film having an interior and exterior side; articulating elements disposed on or within the first film, the articulating elements comprising at least one a folded hinge, a sealed joint, a thinned pathway, a bowed path, an embedded polymeric or metallic cylindrical fiber or rod; and a second film, optionally comprising articulating elements, joined to the first film, to form a biocontainer having a closed volume, wherein the articulating elements permit the biocontainer to expand and collapse along the articulating elements.
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公开(公告)号:US10272639B2
公开(公告)日:2019-04-30
申请号:US15544644
申请日:2016-03-22
Applicant: EMD Millipore Corporation
Inventor: David DeCoste , Joseph Cianciolo , Michael Furbush , John Saragosa
IPC: B32B5/02 , B32B27/08 , B32B27/12 , B32B27/32 , B32B27/34 , B32B27/40 , B01L3/00 , B65D65/40 , B65D75/58 , G01M3/32
Abstract: A biocontainer film enhanced with an abrasion resistant or “cut-proof” substrate. Such substrates can be combined with current biocontainer materials, via various techniques of embedding, coextrusion or laminating, to maintain the cleanliness and low extractables already validated for biotech manufacturing. The substrate of choice may be constructed from materials known to be more resistant to abrasion and sharp razor type cuts or from materials oriented in such a way to prevent puncture to occur. The new substrate must also be flexible to allow for typical folding as demonstrated by current packaging practices. The new substrate may be constructed from materials other than polymers such as metal, glass or carbon or in combination with polymers. A non-constrained pressure test is also disclosed.
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公开(公告)号:US11110684B2
公开(公告)日:2021-09-07
申请号:US16867288
申请日:2020-05-05
Applicant: EMD Millipore Corporation
Inventor: David DeCoste , Joseph Cianciolo , Michael Furbush , John Saragosa
IPC: B32B5/02 , B32B27/08 , B32B27/12 , B32B27/32 , B32B27/34 , B32B27/40 , B01L3/00 , B65D65/40 , B65D75/58 , G01M3/32
Abstract: A multilayered film for biocontainers, an abrasion-resistant substrate attached to the interior or the exterior side of the film wherein the substrate is one of a polymeric woven fibrous material or a polymeric non-woven fibrous material, a woven fibrous material or a non-woven fibrous material having metal fibers, a woven fibrous material or a non-woven fibrous material having glass fibers, or a woven fibrous material or a non-woven fibrous material having carbon fibers; a polymer backing to attach the substrate to the film, including one of polyolefins, polyurethanes and nylons; an outer protective layer disposed on the outside of the substrate to encapsulate the substrate; and a gas impermeable layer that includes ethylene vinyl alcohol disposed intermediate to the substrate and the outer protective layer.
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公开(公告)号:US20200262175A1
公开(公告)日:2020-08-20
申请号:US16867288
申请日:2020-05-05
Applicant: EMD Millipore Corporation
Inventor: David DeCoste , Joseph Cianciolo , Michael Furbush , John Saragosa
IPC: B32B5/02 , G01M3/32 , B65D75/58 , B65D65/40 , B01L3/00 , B32B27/40 , B32B27/34 , B32B27/32 , B32B27/12 , B32B27/08
Abstract: A material for biocontainers including a multilayered film, the multilayered film having an interior and exterior side, an abrasion-resistant substrate attached to the interior or the exterior side of the film wherein the substrate comprises a polymeric woven fibrous material or a polymeric non-woven fibrous material, a woven fibrous material or a non-woven fibrous material comprising metal fibers, a woven fibrous material or a non-woven fibrous material comprising glass fibers, or a woven fibrous material or a non-woven fibrous material comprising carbon fibers; a polymer backing to attach the substrate to the film, the polymer backing comprising one of polyolefins, polyurethanes and nylons; an outer protective layer disposed on the outside of the substrate to encapsulate the substrate; and a gas impermeable layer that includes ethylene vinyl alcohol disposed intermediate to the substrate and the outer protective layer.
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公开(公告)号:US20140252084A1
公开(公告)日:2014-09-11
申请号:US14282831
申请日:2014-05-20
Applicant: EMD Millipore Corporation
Inventor: Aaron Burke , David DeCoste
CPC classification number: B65D25/205 , B31B50/81 , B31D1/028 , B65D33/004 , B65D75/566 , B65D75/5877 , B65D2203/10 , G06K7/10237 , Y10T29/49016 , Y10T156/10
Abstract: The present invention provides a process for incorporating a wireless device into a plastic container as part of the steps of manufacturing the container. The plastic container can be a flexible plastic bag and are formed of one or more sheets, generally two or more sheets of plastic film or a rigid plastic container such as a tub or tote. The bags are formed by sealing together adjacent edge portions of each film layer. One embodiment of the present invention is to incorporate a wireless device between the edge portions of the film(s) before or during sealing so that the wireless device becomes permanently sealed into the film material but is isolated from both the bag interior and the outside environment. Another embodiment is to incorporate the wireless device onto or into a plastic component that is sealed to the container, such as a nipple or port, so that the wireless device becomes permanently sealed to the container but is isolated from both the container interior and the outside environment.
Abstract translation: 本发明提供了一种将无线装置结合到塑料容器中的方法,作为制造容器的步骤的一部分。 塑料容器可以是柔性塑料袋,并且由一个或多个片材形成,一般为两层或更多张塑料薄膜或诸如桶或手提箱的刚性塑料容器。 袋子通过将每个膜层的相邻边缘部分密封在一起而形成。 本发明的一个实施例是在密封之前或期间将无线设备结合在胶片的边缘部分之间,使得无线设备永久地密封到胶片材料中,但与袋内部和外部环境隔离 。 另一个实施例是将无线设备结合到密封到容器(例如乳头或端口)上的塑料部件上,使得无线设备永久地密封到容器,但是与容器内部和外部隔离 环境。
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8.
公开(公告)号:US20190002176A1
公开(公告)日:2019-01-03
申请号:US15743361
申请日:2016-08-15
Applicant: EMD Millipore Corporation
Inventor: Stephen Proulx , David DeCoste
Abstract: A device for storing, transporting and/or handling a liquid or liquids and methods for using the device are described. The device is suitable for use with sterile or aseptic liquids, particularly with large liquid volumes such as 10-1000 liters or more, and avoids the need for bags, bins and carriers commonly used for storing and transporting large volumes of liquids. The device comprises a coiled tubing. The coiled tubing can be loaded onto a spool to support the coiled tubing. The tubing can be filled, sealed, stored and transported in a more robust manner than previously achieved with bags, bins and carriers.
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公开(公告)号:US09889969B2
公开(公告)日:2018-02-13
申请号:US14282831
申请日:2014-05-20
Applicant: EMD Millipore Corporation
Inventor: Aaron Burke , David DeCoste
CPC classification number: B65D25/205 , B31B50/81 , B31D1/028 , B65D33/004 , B65D75/566 , B65D75/5877 , B65D2203/10 , G06K7/10237 , Y10T29/49016 , Y10T156/10
Abstract: The present invention provides a process for incorporating a wireless device into a plastic container as part of the steps of manufacturing the container. The plastic container can be a flexible plastic bag and are formed of one or more sheets, generally two or more sheets of plastic film or a rigid plastic container such as a tub or tote. The bags are formed by sealing together adjacent edge portions of each film layer. One embodiment of the present invention is to incorporate a wireless device between the edge portions of the film(s) before or during sealing so that the wireless device becomes permanently sealed into the film material but is isolated from both the bag interior and the outside environment. Another embodiment is to incorporate the wireless device onto or into a plastic component that is sealed to the container, such as a nipple or port, so that the wireless device becomes permanently sealed to the container but is isolated from both the container interior and the outside environment.
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公开(公告)号:US20170368790A1
公开(公告)日:2017-12-28
申请号:US15544644
申请日:2016-03-22
Applicant: EMD Millipore Corporation
Inventor: David DeCoste , Joseph Cianciolo , Michael Furbush , John Saragosa
IPC: B32B5/02 , B65D75/58 , B32B27/08 , B32B27/12 , B32B27/32 , B32B27/40 , G01M3/32 , B65D65/40 , B01L3/00
CPC classification number: B32B5/024 , B01L3/508 , B01L2300/0887 , B01L2300/16 , B32B5/02 , B32B5/022 , B32B27/08 , B32B27/12 , B32B27/32 , B32B27/34 , B32B27/40 , B32B2262/0253 , B32B2262/0261 , B32B2262/0269 , B32B2262/0276 , B32B2262/103 , B32B2262/106 , B32B2307/554 , B32B2307/7242 , B32B2439/40 , B32B2439/80 , B65D65/40 , B65D75/58 , B65D2275/00 , G01M3/3272
Abstract: A biocontainer film enhanced with an abrasion resistant or “cut-proof” substrate. Such substrates can be combined with current biocontainer materials, via various techniques of embedding, coextrusion or laminating, to maintain the cleanliness and low extractables already validated for biotech manufacturing. The substrate of choice may be constructed from materials known to be more resistant to abrasion and sharp razor type cuts or from materials oriented in such a way to prevent puncture to occur. The new substrate must also be flexible to allow for typical folding as demonstrated by current packaging practices. The new substrate may be constructed from materials other than polymers such as metal, glass or carbon or in combination with polymers. A non-constrained pressure test is also disclosed.
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