公开(公告)号：US20240148856A1

公开(公告)日：2024-05-09

申请号：US18495475

申请日：2023-10-26

Applicant: EUBIOLOGICS CO., LTD.

Inventor： Chan Kyu LEE ,  Jonathan F. LOVELL ,  Yoon Hee WHANG ,  Woo Yeon HWANG ,  Hye Ji KIM ,  Min Chul PARK ,  Seok Kyu KIM ,  Wei-Chiao HUANG ,  Da Hui HA

IPC: A61K39/155 ,  A61P31/14 ,  C07K1/18 ,  C07K1/22 ,  C07K7/00 ,  C07K14/005 ,  C12N5/071

CPC classification number: A61K39/155 ,  A61P31/14 ,  C07K1/18 ,  C07K1/22 ,  C07K7/00 ,  C07K14/005 ,  C12N5/0682 ,  A61K2039/55555

Abstract: Provided is a vaccine composition for preventing respiratory syncytial virus (RSV) infection, which is in the form of a liposome formulation including a RSV antigen, monophosphoryl lipid A (MLA), and/or a cobalt-porphyrin-phospholipid (CoPoP) conjugate. The vaccine composition exhibits excellent vaccine efficacy from a RSV antigen with enhanced immunogenicity and a combination of immune adjuvants for enhancing immune activity and antigen presentation.