公开(公告)号：US20210207224A1

公开(公告)日：2021-07-08

申请号：US17205796

申请日：2021-03-18

Applicant: Mayo Foundation for Medical Education and Research ,  Exact Sciences Development Company, LLC

Inventor： David A. Ahlquist ,  William R. Taylor ,  Douglas W. Mahoney ,  Tracy C. Yab ,  John B. Kisiel ,  Hatim T. Allawi ,  Graham P. Lidgard ,  Michael W. Kaiser

IPC: C12Q1/6886 ,  C12Q1/6853 ,  G16H50/30 ,  C12Q1/6806 ,  C12Q1/6809 ,  C12Q1/6811 ,  C12Q1/6837 ,  C12Q1/6827 ,  C12Q1/682

Abstract: Provided herein is technology for breast cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of breast cancer.

公开(公告)号：US20210172027A1

公开(公告)日：2021-06-10

申请号：US17178110

申请日：2021-02-17

Applicant: Mayo Foundation for Medical Education and Research ,  Exact Sciences Development Company, LLC

Inventor： David A. Ahlquist ,  William R. Taylor ,  Douglas W. Mahoney ,  Tracy C. Yab ,  John B. Kisiel ,  Hatim T. Allawi ,  Graham P. Lidgard ,  Michael W. Kaiser

IPC: C12Q1/6886 ,  C12Q1/6806 ,  C12Q1/6809 ,  C12Q1/6811 ,  C12Q1/6827 ,  C12Q1/6837 ,  C12Q1/6853 ,  G16H50/30 ,  C12Q1/682

Abstract: Provided herein is technology for breast cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of breast cancer.

公开(公告)号：US10934594B2

公开(公告)日：2021-03-02

申请号：US16202944

申请日：2018-11-28

Applicant: Mayo Foundation for Medical Education and Research ,  Exact Sciences Development Company, LLC

Inventor： David A. Ahlquist ,  William R. Taylor ,  Douglas W. Mahoney ,  Tracy C. Yab ,  John B. Kisiel ,  Hatim T. Allawi ,  Graham P. Lidgard ,  Michael W. Kaiser

IPC: C12Q1/68 ,  C07H21/04 ,  C12Q1/6886 ,  C12Q1/6853 ,  G16H50/30 ,  C12Q1/6806 ,  C12Q1/6809 ,  C12Q1/6811 ,  C12Q1/6837 ,  C12Q1/6827 ,  C12Q1/682

Abstract: Provided herein is technology for breast cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of breast cancer.

公开(公告)号：US10648025B2

公开(公告)日：2020-05-12

申请号：US15841006

申请日：2017-12-13

Applicant: EXACT SCIENCES DEVELOPMENT COMPANY, LLC

Inventor： Hatim T. Allawi ,  William G. Weisburg ,  Graham P. Lidgard ,  Michael W. Kaiser ,  Abram M. Vaccaro ,  Gracie Shea

IPC: C12Q1/686 ,  C12Q1/6827 ,  C12P19/34 ,  C12N15/65 ,  C01B17/48

Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.

公开(公告)号：US20190161806A1

公开(公告)日：2019-05-30

申请号：US16202944

申请日：2018-11-28

Applicant: Mayo Foundation for Medical Education and Research ,  Exact Sciences Development Company, LLC

Inventor： David A. Ahlquist ,  William R. Taylor ,  Douglas W. Mahoney ,  Tracy C. Yab ,  John B. Kisiel ,  Hatim T. Allawi ,  Graham P. Lidgard ,  Michael W. Kaiser

IPC: C12Q1/6886 ,  C12Q1/6827 ,  C12Q1/682

Abstract: Provided herein is technology for breast cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of breast cancer.

公开(公告)号：US10975443B2

公开(公告)日：2021-04-13

申请号：US16202935

申请日：2018-11-28

Applicant: Mayo Foundation for Medical Education and Research ,  Exact Sciences Development Company, LLC

Inventor： David A. Ahlquist ,  William R. Taylor ,  Douglas W. Mahoney ,  Tracy C. Yab ,  John B. Kisiel ,  Hatim T. Allawi ,  Graham P. Lidgard ,  Michael W. Kaiser

IPC: C12Q1/68 ,  C07H21/04 ,  C12Q1/6886 ,  C12Q1/6853 ,  G16H50/30 ,  C12Q1/6806 ,  C12Q1/6809 ,  C12Q1/6811 ,  C12Q1/6837 ,  C12Q1/6827 ,  C12Q1/682

Abstract: Provided herein is technology for breast cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of breast cancer.

公开(公告)号：US20200248233A1

公开(公告)日：2020-08-06

申请号：US16789279

申请日：2020-02-12

Applicant: EXACT SCIENCES DEVELOPMENT COMPANY, LLC

Inventor： Hatim T. Allawi ,  William G. Weisburg ,  Graham P. Lidgard ,  Michael W. Kaiser ,  Abram M. Vaccaro ,  Gracie Shea

IPC: C12Q1/686 ,  C12Q1/6827 ,  C12N15/65

Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.

公开(公告)号：US11193168B2

公开(公告)日：2021-12-07

申请号：US16789279

申请日：2020-02-12

Applicant: EXACT SCIENCES DEVELOPMENT COMPANY, LLC

Inventor： Hatim T. Allawi ,  William G. Weisburg ,  Graham P. Lidgard ,  Michael W. Kaiser ,  Abram M. Vaccaro ,  Gracie Shea

IPC: C12Q1/686 ,  C12Q1/6827 ,  C12N15/65 ,  C01B17/48

Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.

公开(公告)号：US10822638B2

公开(公告)日：2020-11-03

申请号：US15335111

申请日：2016-10-26

Applicant: EXACT SCIENCES DEVELOPMENT COMPANY, LLC

Inventor： Hatim Allawi ,  Graham P. Lidgard ,  Brian Aizenstein ,  Tamara J. Sander ,  Maria Giakoumopoulos ,  Michael W. Kaiser ,  Melissa M. Gray ,  Abram Michael Vaccaro

IPC: C12N15/00 ,  C12Q1/6806 ,  C12Q1/686 ,  C12N15/10 ,  C12Q1/6837

Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.

公开(公告)号：US20190177769A1

公开(公告)日：2019-06-13

申请号：US15841006

申请日：2017-12-13

Applicant: EXACT SCIENCES DEVELOPMENT COMPANY, LLC

Inventor： Hatim T. Allawi ,  William G. Weisburg ,  Graham P. Lidgard ,  Michael W. Kaiser ,  Abram M. Vaccaro ,  Gracie Shea

IPC: C12Q1/686 ,  C12N15/65

Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.