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公开(公告)号：US5407742A
公开(公告)日：1995-04-18
申请号：US830104
申请日：1992-02-03
CPC分类号： B32B27/06 , B65D35/02 , Y10T428/1303 , Y10T428/1307 , Y10T428/1338 , Y10T428/1341 , Y10T428/1352 , Y10T428/1359 , Y10T428/1379 , Y10T428/139 , Y10T428/1393 , Y10T428/31681 , Y10T428/31786 , Y10T428/31797
摘要： A structure which is useful for making containers for dentifrices, such as tubes, is comprised of a structure where the layer which contacts the dentifrice consists of a blend of polybutylene terephthalate and polyethylene. Other layers can consist of adhesives, paper, foils, other polymers and the like depending on the properties desired. A polybutylene terephthalate-polyethylene layer has been found to have a low degree of absorption of flavorant.
摘要翻译： 用于制造用于洁牙剂的容器（例如管）的结构包括其中与洁齿剂接触的层由聚对苯二甲酸丁二醇酯和聚乙烯的共混物组成的结构。 根据所需的性质，其它层可以由粘合剂，纸，箔，其它聚合物等组成。 已经发现聚对苯二甲酸丁二醇酯 - 聚乙烯层具有低的食用香料吸收度。
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2.发明授权
公开(公告)号：US4693396A
公开(公告)日：1987-09-15
申请号：US902120
申请日：1986-09-02
CPC分类号： B32B15/08 , B65D35/04 , Y10T428/1303 , Y10T428/31703 , Y10T428/31895
摘要： There is disclosed a substrate of layers of materials comprising fluorinated polyethylene layers having sandwiched therein between a metal foil layer and a paper layer all suitably adhered to one another. It is also contemplated that the substrate be employed in fabricating a dentifrice tube.
摘要翻译： 公开了一种包含氟化聚乙烯层的材料层的基材，其夹在金属箔层和纸层之间，所有这些材料都彼此适当地粘合。 还可以设想，该基底用于制造洁齿管。
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3.发明授权Ethylene propylene copolymer in a substrate and collapsible dispensing container made therefrom 失效基材中的乙烯丙烯共聚物和由其制成的可折叠分配容器
公开(公告)号：US4693395A
公开(公告)日：1987-09-15
申请号：US902119
申请日：1986-09-02
CPC分类号： B32B15/08 , Y10T428/1303 , Y10T428/31703 , Y10T428/31895
摘要： There is disclosed a substrate of layers of materials comprising ethylene propylene copolymer layers having sandwiched therein between a metal foil layer and a paper layer all suitably adhered to one another. It is also contemplated that the substrate be employed in fabricating a dentifrice tube.
摘要翻译： 公开了一种包含乙烯丙烯共聚物层的材料层的基材，所述乙烯丙烯共聚物层夹在金属箔层和纸层之间，均匀地彼此粘附。 还可以设想，该基底用于制造洁齿管。
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4.发明授权Dispensing container made from an ethylene vinyl alcohol containing laminated material and the material therefor 失效由含有乙烯乙烯醇的层压材料制成的分配容器及其材料
公开(公告)号：US4951841A
公开(公告)日：1990-08-28
申请号：US687555
申请日：1984-12-28
CPC分类号： B65D35/14 , B32B15/08 , Y10T428/1379 , Y10T428/31895 , Y10T428/3192
摘要： There is disclosed a substrate of layers of materials comprising ethylene vinyl alcohol copolymer layers having sandwiched therein between a metal foil layer and a paper layer all suitably adhered to one another. It is also contemplated that the substrate be employed in fabricating a dentifrice tube.
摘要翻译： 公开了一种包含乙烯乙烯醇共聚物层的材料层的基材，其中金属箔层和纸层之间夹在其中，所有这些均匀地彼此粘附。 还可以设想，该基底用于制造洁齿管。
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公开(公告)号：US06464963B1
公开(公告)日：2002-10-15
申请号：US09065267
申请日：1998-04-23
IPC分类号： A61K716
CPC分类号： A61Q11/00 , A61K8/19 , A61K2800/88
摘要： A two component desensitizing dentifrice composition is disclosed which comprises a first dentifrice component containing a desensitizing potassium salt such as potassium nitrate and an alkali metal compound such as NaOH and a second dentifrice component containing a desensitizing stannous salt source such as stannous, the first and second dentifrice components being maintained separate from the other until dispensed for application to teeth.
摘要翻译： 公开了一种双组分脱敏洁牙剂组合物，其包含含有脱敏钾盐如硝酸钾和碱金属化合物如NaOH的第一洁齿剂组分和含有脱敏亚锡盐源的第二洁齿剂组分，例如亚锡，第一和第二 洁齿剂组分被保持分开，直到分配用于施用于牙齿。
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公开(公告)号：US5658554A
公开(公告)日：1997-08-19
申请号：US456586
申请日：1995-06-01
申请人： Steven W. Fisher , Edward A. Tavss , Shannon K. Campbell , Marilou T. Joziak , Karen J. De Pierro , John P. Curtis
发明人： Steven W. Fisher , Edward A. Tavss , Shannon K. Campbell , Marilou T. Joziak , Karen J. De Pierro , John P. Curtis
CPC分类号： A61K33/42
摘要： A mouth moistener for alleviating dry mouth condition comprised of an aqueous vehicle containing less than about 2% by weight an edible organic acid such as citric or malic acid and a mixture of a water soluble calcium ion releasing salt and a water soluble phosphate ion releasing salt, wherein the solution is unsaturated with respect to calcium phosphate and the solubility product (S.P.) of the calcium and phosphate ion concentration present in the solution, as expressed by the equationS.P.=[Ca][PO.sub.4 ].sup.2is less than about 0.004, wherein [Ca] is the molar concentration of the released calcium ions and [PO.sub.4 ] is the molar concentration of the released phosphate ion.
摘要翻译： 一种用于缓解口干症状的口腔保湿剂，其由含有少于约2重量％的可食用有机酸如柠檬酸或苹果酸的水性载体和水溶性钙离子释放盐和水溶性磷酸盐离子释放盐的混合物组成 ，其中所述溶液相对于磷酸钙是不饱和的，并且如方程式P = [Ca] [PO 4] 2所表示的溶液中存在的钙和磷酸根离子浓度的溶解度积（SP）小于约0.004 其中[Ca]是释放的钙离子的摩尔浓度，[PO4]是释放的磷酸根离子的摩尔浓度。
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7.发明授权Laminated polyester containing substrate and collapsible dispensing container made therefrom 失效层压聚酯基材和由其制成的可折叠分配容器
公开(公告)号：US4595612A
公开(公告)日：1986-06-17
申请号：US739486
申请日：1985-05-30
申请人： Edward A. Tavss , Samuel C. Temin
发明人： Edward A. Tavss , Samuel C. Temin
CPC分类号： B32B15/08 , B65D35/02 , Y10T428/1303 , Y10T428/1359 , Y10T428/31681 , Y10T428/31703 , Y10T428/3179 , Y10T428/31993
摘要： There is disclosed a substrate of layers of materials comprising polyester layers having sandwiched therein between a metal foil layer and a paper layer all suitably adhered to one another. It is also contemplated that the substrate be employed in fabricating a dentifrice tube.
摘要翻译： 公开了一种材料层的基材，其包括夹在金属箔层和纸层之间的聚酯层，所有这些均匀地彼此粘合。 还可以设想，该基底用于制造洁齿管。
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公开(公告)号：US4992256A
公开(公告)日：1991-02-12
申请号：US413424
申请日：1989-09-27
IPC分类号： G01N33/50 , A61K8/00 , A61K8/34 , A61K8/46 , A61K9/12 , A61K9/68 , A61K49/00 , A61Q11/00 , C12Q1/04
CPC分类号： A61Q11/00 , A61K8/466 , A61K2800/43
摘要： Dental plaque-disclosing compositions comprising FD&C Red No. 40 which selectively stain plaque formed on tooth surfaces, making plaque easily observable to the naked eye at visible light wave-lengths.
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公开(公告)号：US06346235B1
公开(公告)日：2002-02-12
申请号：US09519507
申请日：2000-03-06
IPC分类号： A61K716
CPC分类号： A61Q11/00 , A61K8/21 , A61K8/24 , A61K8/25 , A61K2800/88
摘要： A method is disclosed for enhancing fluoride availability using an acidulated two component dentifrice system in which the first component contains sodium fluoride and a silica abrasive in an alkaline environment and the second component contains an acid, a phosphate ion source, and a silica abrasive.
摘要翻译： 公开了一种使用酸化双组分洁齿剂体系来提高氟化物可利用率的方法，其中第一组分在碱性环境中含有氟化钠和二氧化硅磨料，第二组分含有酸，磷酸根离子源和二氧化硅磨料。
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公开(公告)号：US4391798A
公开(公告)日：1983-07-05
申请号：US357918
申请日：1982-03-15
申请人： Edward A. Tavss , Edward Eigen
发明人： Edward A. Tavss , Edward Eigen
IPC分类号： A61K8/21 , A61K20060101 , A61K8/40 , A61K8/44 , A61K8/46 , A61K8/64 , A61K9/16 , A61K9/18 , A61Q11/00 , A61K7/22
CPC分类号： A61Q11/00 , A61K8/463 , A61K8/64 , A61K2800/75
摘要： A dentifrice composition containing an anionic surfactant, and a minor amount of a water soluble positively charged protein hydrolysate having an isoionic point above 7, and a Bloom gel value of zero, selected from the group consisting of a protein hydrolysate fraction containing high concentrations of basic amino acids or a quaternary derivative of a protein hydrolysate, which counters the irritation to the oral tissue and reduces the bitterness caused by said anionic surfactant, without reducing its foaming and cleansing properties.The present invention relates to novel oral compositions which are substantially non-irritating to the oral tissue, comprising an anionic surfactant and a positively charged water soluble protein hydrolysate fraction containing a high concentration of basic amino acids or a quaternary derivative of a protein hydrolysate. The protein hydrolysate fraction is obtained by extraction from a partially hydrolyzed protein mixture by means of ion exchange separation with an anion exchange resin. The quaternary derivative is obtained by quaternizing a protein hydrolysate mixture by chemically modifying the available terminal amino groups of the protein.
摘要翻译： 含有阴离子表面活性剂的洁牙剂组合物和少量具有高于7的等离子点的水溶性带正电荷的蛋白质水解产物和Bloom凝胶值为零，选自含有高浓度碱性的蛋白质水解产物 氨基酸或蛋白质水解产物的季衍生物，其反映了对口腔组织的刺激，并降低了由所述阴离子表面活性剂引起的苦味，而不降低其起泡和清洁性能。 本发明涉及对口腔组织基本无刺激性的新型口服组合物，其包含阴离子表面活性剂和含有高浓度碱性氨基酸或蛋白质水解产物的季衍生物的带正电荷的水溶性蛋白质水解产物级分。 通过用阴离子交换树脂通过离子交换分离从部分水解的蛋白质混合物中提取蛋白质水解产物级分。 通过化学修饰蛋白质的可用末端氨基，通过蛋白质水解产物混合物季铵化获得季衍生物。
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