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15 条记录 (耗时 0.021 秒)

    Plaque inhibition with antiplaque oral composition dispensed from container having polymeric material in contact and compatible with the composition
    3.
    发明授权
    Plaque inhibition with antiplaque oral composition dispensed from container having polymeric material in contact and compatible with the composition 失效
    从具有接触并与组合物相容的聚合材料的容器分配的抗斑块口服组合物的斑块抑制

    公开(公告)号：US5496540A

    公开(公告)日：1996-03-05

    申请号：US179272

    申请日：1994-01-10

    申请人： Abdul Gaffar ,  Richard S. Robinson ,  Jeffrey Miller ,  Chimpiramma Potini ,  Michael A. Collins ,  Theresa G. Shackil

    发明人： Abdul Gaffar ,  Richard S. Robinson ,  Jeffrey Miller ,  Chimpiramma Potini ,  Michael A. Collins ,  Theresa G. Shackil

    IPC分类号： A61K8/04 ,  A61K8/24 ,  A61K8/34 ,  A61Q11/00 ,  A61K7/16 ,  A61K7/18

    CPC分类号： A61K8/046 ,  A61K8/24 ,  A61K8/347 ,  A61Q11/00 ,  Y10S514/90 ,  Y10S514/901 ,  Y10S514/902

    摘要： An oral composition, such as a paste or gel dentifrice or a liquid mouthwash, containing a substantially water insoluble non-cationic antibacterial agent, such as triclosan, which, when used to clean the teeth or rinse the mouth, acts to decrease plaque on the teeth, is packaged in a dispensing container which includes a solid polymeric material, such as polyfluoroethylene, which is compatible with the antibacterial agent so that excessive loss of anti-plaque activity of such agent on storage is avoided. Alternatively, various other polymers may be employed as container parts, which normally would cause excessive losses of anti-plaque action of the antibacterial agent in the composition, but such action is countered by the presence of a stabilizer, such as a terpene, e.g., limonene, in the oral composition formula. The oral composition preferably contains a tooth hardening proportion of a source of fluoride ions, an anti-tartar proportion of a polyphosphate, a stabilizing proportion (in conjunction with the fluoride source) for the polyphosphate, of a polyvinyl methyl ether-maleic anhydride copolymer, and normal adjuvants for the oral preparation. A method for inhibiting development of plaque on teeth is also within the invention, as is a cleaning article containing an effective amount of the invented dentifrice.

    摘要翻译： 包含基本上不溶于水的非阳离子抗菌剂（例如三氯生）的口服组合物，例如糊剂或凝胶洁齿剂或液体漱口剂，其用于清洁牙齿或冲洗口腔时起作用以减少 牙齿被包装在分配容器中，该分配容器包括与抗菌剂相容的固体聚合物材料，例如聚氟乙烯，从而避免了这种药剂在储存时过度的抗斑块活性损失。 或者，可以使用各种其它聚合物作为容器部件，其通常将导致组合物中抗菌剂的抗斑块作用的过度损失，但是这种作用由稳定剂如萜烯的存在来抵消，例如， 柠檬烯，口服组合物配方。 口服组合物优选含有聚乙烯基醚 - 马来酸酐共聚物的氟化物离子源，多磷酸盐的抗牙垢比例，多磷酸盐的稳定化比例（与氟化物源结合）的牙齿硬化比例， 和用于口服制剂的正常佐剂。 抑制牙齿斑块发展的方法也在本发明的范围内，含有有效量的本发明洁牙剂的清洁用品也是如此。

    Plaque inhibition with antiplaque oral composition dispensed from container having polymeric material in contact and compatible with the composition
    4.
    发明授权
    Plaque inhibition with antiplaque oral composition dispensed from container having polymeric material in contact and compatible with the composition 失效
    从具有接触并与组合物相容的聚合材料的容器分配的抗斑块口服组合物的斑块抑制

    公开(公告)号：US5279813A

    公开(公告)日：1994-01-18

    申请号：US931622

    申请日：1992-08-18

    申请人： Abdul Gaffar ,  Richard S. Robinson ,  Jeffrey Miller ,  Chimpiramma Potini ,  Michael A. Collins ,  Theresa G. Shackil

    发明人： Abdul Gaffar ,  Richard S. Robinson ,  Jeffrey Miller ,  Chimpiramma Potini ,  Michael A. Collins ,  Theresa G. Shackil

    IPC分类号： A61K8/04 ,  A61K8/24 ,  A61K8/34 ,  A61Q11/00 ,  A61K7/16

    CPC分类号： A61K8/046 ,  A61K8/24 ,  A61K8/347 ,  A61Q11/00 ,  Y10S514/90 ,  Y10S514/901 ,  Y10S514/902

    摘要： An oral composition, such as a paste or gel dentifrice or a liquid mouthwash, containing a substantially water insoluble non-cationic antibacterial agent, such as triclosan, which, when used to clean the teeth or rinse the mouth, acts to decrease plaque on the teeth, is packaged in a dispensing container which includes a solid polymeric material, such as polyfluoroethylene, which is compatible with the antibacterial agent so that excessive loss of anti-plaque activity of such agent on storage is avoided. Alternatively, various other polymers may be employed as container parts, which normally would cause excessive losses of anti-plaque action of the antibacterial agent in the composition but such action is countered by the presence of a stabilizer, such as a terpene, e.g., limonene, in the oral composition formula. The oral composition preferably contains a tooth hardening proportion of a source of fluoride ions, an anti-tartar proportion of a polyphosphate, a stabilizing proportion (in conjunction with the fluoride source) for the polyphosphate, of a polyvinyl methyl ether-maleic anhydride copolymer, and normal adjuvants for the oral preparation. A method for inhibiting development of plaque on teeth is also within the invention, as is a cleaning article containing an effective amount of the invented dentifrice.

    摘要翻译： 包含基本上不溶于水的非阳离子抗菌剂（例如三氯生）的口服组合物，例如糊剂或凝胶洁齿剂或液体漱口剂，其用于清洁牙齿或冲洗口腔时起作用以减少 牙齿被包装在分配容器中，该分配容器包括与抗菌剂相容的固体聚合物材料，例如聚氟乙烯，从而避免了这种药剂在储存时过度的抗斑块活性损失。 或者，可以使用各种其它聚合物作为容器部件，其通常将导致组合物中抗菌剂的抗斑块作用的过度损失，但是这种作用通过稳定剂如萜烯的存在来抵消，例如苎烯 ，在口服组合物配方中。 口服组合物优选含有聚乙烯基醚 - 马来酸酐共聚物的氟化物离子源，多磷酸盐的抗牙垢比例，多磷酸盐的稳定化比例（与氟化物源结合）的牙齿硬化比例， 和用于口服制剂的正常佐剂。 抑制牙齿斑块发展的方法也在本发明的范围内，含有有效量的本发明洁牙剂的清洁用品也是如此。

    Article comprising a dispensing container of polymeric material in contact with an antiplaque oral composition with which it is compatible
    7.
    发明授权
    Article comprising a dispensing container of polymeric material in contact with an antiplaque oral composition with which it is compatible 失效
    包含聚合物质分配容器的文章与其兼容的ANTIPLAQUE口味组合物接触

    公开(公告)号：US5135738A

    公开(公告)日：1992-08-04

    申请号：US427660

    申请日：1989-10-26

    申请人： Abdul Gaffar ,  Richard S. Robinson ,  Jeffrey Miller ,  Chimpiramma Potini ,  Michael A. Collins ,  Theresa G. Shackil

    发明人： Abdul Gaffar ,  Richard S. Robinson ,  Jeffrey Miller ,  Chimpiramma Potini ,  Michael A. Collins ,  Theresa G. Shackil

    IPC分类号： A61K8/34 ,  A61K8/81 ,  A61Q11/00

    CPC分类号： A61Q11/00 ,  A61K8/347 ,  A61K8/8164 ,  A61K2800/87 ,  Y10S514/90 ,  Y10S514/901 ,  Y10S514/902

    摘要： An oral composition, such as a paste or gel dentifrice or a liquid mouthwash, containing a substantially water insoluble non-cationic antibacterial agent, such as triclosan, which, when used to clean the teeth or rinse the mouth, acts to decrease plaque on the teeth, is packaged in a dispensing container or bottle which includes a solid polymeric material, such as polyfluoroethylene, which is compatible with the antibacterial agent so that excessive loss of anti-plaque acitivity of such agent on storage is avoided. Alternatively, various other polymers may be employed as container parts, which normally would cause excessive losses of anti-plaque action of the antibacterial agent in the composition but such action is countered by the presence of a stabilizer, such as a terpene, e.g., limonene, in the oral composition formula. Also described is a method for inhibiting development of plaque on teeth.

    摘要翻译： 包含基本上不溶于水的非阳离子抗菌剂（例如三氯生）的口服组合物，例如糊剂或凝胶洁齿剂或液体漱口剂，其用于清洁牙齿或冲洗口腔时起作用以减少 牙齿被包装在分配容器或瓶子中，该分配容器或瓶子包括与抗菌剂相容的固体聚合材料，例如聚氟乙烯，从而避免了这种药剂在储存时过量的抗斑块活性丧失。 或者，可以使用各种其它聚合物作为容器部件，其通常将导致组合物中抗菌剂的抗斑块作用的过度损失，但是这种作用通过稳定剂如萜烯的存在来抵消，例如苎烯 ，在口服组合物配方中。 还描述了抑制牙齿斑块发展的方法。

    Packaged anti-plaque oral compositions
    10.
    发明授权
    Packaged anti-plaque oral compositions 失效
    包装的抗斑块口服组合物

    公开(公告)号：US5273741A

    公开(公告)日：1993-12-28

    申请号：US922252

    申请日：1992-07-30

    申请人： Abdul Gaftar ,  Richard S. Robinson ,  Jeffrey Miller ,  Chimpiramma Potini ,  Michael A. Collins ,  Theresa G. Shackil

    发明人： Abdul Gaftar ,  Richard S. Robinson ,  Jeffrey Miller ,  Chimpiramma Potini ,  Michael A. Collins ,  Theresa G. Shackil

    IPC分类号： A61K8/34 ,  A61Q11/00 ,  A61K7/16 ,  A61K7/18 ,  A61K7/26

    CPC分类号： A61Q11/00 ,  A61K8/347 ,  A61K2800/87 ,  Y10S514/90 ,  Y10S514/901 ,  Y10S514/902

    摘要： An oral composition, such as a paste or gel dentifrice or a liquid mouthwash, containing a substantially water insoluble non-cationic antibacterial agent, such as triclosan, which, when used to clean the teeth or rinse the mouth, acts to decrease plaque on the teeth, is packaged in a dispensing container or bottle which includes a solid polymeric material, such as polyfluoroethylene, which is compatible with the antibacterial agent so that excessive loss of anti-plaque activity of such agent on storage is avoided. Alternatively, various other polymers may be employed as container parts, which normally would cause excessive losses of anti-plaque action of the antibacterial agent in the composition but such action is countered by the presence of a stabilizer, such as a terpene, e.g., limonene, in the oral composition formula. Also described is a method for inhibiting development of plaque on teeth.

    摘要翻译： 包含基本上不溶于水的非阳离子抗菌剂（例如三氯生）的口服组合物，例如糊剂或凝胶洁齿剂或液体漱口剂，其用于清洁牙齿或冲洗口腔时起作用以减少 牙齿包装在分配容器或瓶子中，该分配容器或瓶子包括与抗菌剂相容的诸如聚氟乙烯的固体聚合物材料，从而避免了这种药剂在储存时过度的抗斑块活性损失。 或者，可以使用各种其它聚合物作为容器部件，其通常将导致组合物中抗菌剂的抗斑块作用的过度损失，但是这种作用通过稳定剂如萜烯的存在来抵消，例如苎烯 ，在口服组合物配方中。 还描述了抑制牙齿斑块发展的方法。