公开(公告)号：US10407439B2

公开(公告)日：2019-09-10

申请号：US15906401

申请日：2018-02-27

Applicant: Eisai R&D Management Co., Ltd.

Inventor： Francis G. Fang ,  Hyeong-Wook Choi ,  Silvio Campagna ,  Steven Mathieu

IPC: C07D493/22 ,  C07D493/08 ,  C07D493/18 ,  C07B57/00 ,  C07D313/00

Abstract: The present invention relates to stereochemically defined polypropionates and methods for preparing and using the same. The stereochemically defined polypropionates may be useful in the synthesis of natural products and/or natural product-like libraries.

公开(公告)号：US10160768B2

公开(公告)日：2018-12-25

申请号：US15501658

申请日：2015-08-04

Applicant: Eisai R&D Management Co., Ltd.

Inventor： Francis G. Fang ,  Hyeong-Wook Choi ,  Silvio Campagna ,  Steven Mathieu

IPC: C07D493/18 ,  C07D493/22 ,  C07B57/00 ,  C07D313/00 ,  C07D493/08

Abstract: The present invention relates to stereochemically defined polypropionates and methods for preparing and using the same. The stereochemically defined polypropionates may be useful in the synthesis of natural products and/or natural product-like libraries.

公开(公告)号：US10793581B2

公开(公告)日：2020-10-06

申请号：US16521691

申请日：2019-07-25

Applicant: Eisai R&D Management Co., Ltd.

Inventor： Francis G. Fang ,  Hyeong-wook Choi ,  Silvio Campagna ,  Steven Mathieu

IPC: C07D493/22 ,  C07B57/00 ,  C07D313/00 ,  C07D493/08 ,  C07D493/18

Abstract: The present invention relates to stereochemically defined polypropionates and methods for preparing and using the same. The stereochemically defined polypropionates may be useful in the synthesis of natural products and/or natural product-like libraries.

公开(公告)号：USRE47797E1

公开(公告)日：2020-01-07

申请号：US15944480

申请日：2018-04-03

Applicant: EISAI R&D MANAGEMENT CO., LTD.

Inventor： Farid Benayoud ,  Trevor Lee Calkins ,  Charles E. Chase ,  William Christ ,  Bryan M. Lewis ,  Matthew Schnaderbeck ,  Marc Pesant ,  Brian Austad ,  Silvio Campagna ,  Yongbo Hu ,  Gordon Wilkie ,  Xiaojie Zhu ,  Francis G. Fang

IPC: C07D307/28 ,  C07F7/18 ,  C07C33/42 ,  C07D407/06 ,  C07D407/14 ,  C07D493/04 ,  C07D493/08 ,  C07D493/18 ,  C07D493/22 ,  C07D493/20 ,  C07D317/72 ,  C07H15/26 ,  A61K31/341 ,  C07D307/12 ,  C07D493/10 ,  C07D307/33

Abstract: Intermediates and methods of their use in the synthesis of analogs of halichondrin B are provided.