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公开(公告)号:US5116738A
公开(公告)日:1992-05-26
申请号:US692827
申请日:1991-04-26
申请人: Elizabeth A. Wang , John M. Wozney , Vicki Rosen
发明人: Elizabeth A. Wang , John M. Wozney , Vicki Rosen
CPC分类号: C07K14/51 , A61L24/043 , A61L27/227 , A61K38/00
摘要: Purified BMP-3 proteins and processes for producing them are disclosed. They may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
摘要翻译: 公开了纯化的BMP-3蛋白质及其生产方法。 它们可用于治疗骨和软骨缺损以及伤口愈合和相关组织修复。
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公开(公告)号:US06177406B1
公开(公告)日:2001-01-23
申请号:US08927124
申请日:1997-09-05
申请人: Elizabeth A. Wang , John M. Wozney , Vicki Rosen
发明人: Elizabeth A. Wang , John M. Wozney , Vicki Rosen
IPC分类号: A61K3818
CPC分类号: C07K14/51 , A61K38/00 , A61L24/043 , A61L27/227 , C08L89/00
摘要: Purified BMP-3 proteins and processes for producing them are disclosed. They may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
摘要翻译: 公开了纯化的BMP-3蛋白质及其生产方法。 它们可用于治疗骨和软骨缺损以及伤口愈合和相关组织修复。
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公开(公告)号:US06432919B1
公开(公告)日:2002-08-13
申请号:US07655578
申请日:1991-03-04
申请人: Elizabeth A. Wang , John M. Wozney , Vicki Rosen
发明人: Elizabeth A. Wang , John M. Wozney , Vicki Rosen
IPC分类号: A61K3816
CPC分类号: C07K14/51 , A61K38/00 , A61L24/043 , A61L27/227 , C08L89/00
摘要: Purified BMP-3 proteins and processes for producing them are disclosed. They may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
摘要翻译: 公开了纯化的BMP-3蛋白质及其生产方法。 它们可用于治疗骨和软骨缺损以及伤口愈合和相关组织修复。
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公开(公告)号:US4877864A
公开(公告)日:1989-10-31
申请号:US31346
申请日:1987-03-26
申请人: Elizabeth A. Wang , John M. Wozney , Vicki Rosen
发明人: Elizabeth A. Wang , John M. Wozney , Vicki Rosen
CPC分类号: C07K14/51 , A61K35/32 , A61L24/043 , A61L27/227 , A61K38/00
摘要: Human and bovine bone inductive factors are provided. Such factors may be produced by recombinant techniques and be useful in the treatment of bone defects.
摘要翻译: 提供了人骨和牛骨诱导因子。 这些因素可以通过重组技术产生并且可用于治疗骨缺损。
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公开(公告)号:US5618924A
公开(公告)日:1997-04-08
申请号:US655579
申请日:1991-03-18
申请人: Elizabeth A. Wang , John M. Wozney , Vicki Rosen
发明人: Elizabeth A. Wang , John M. Wozney , Vicki Rosen
IPC分类号: A61K38/00 , A61L24/04 , A61L27/22 , C07K14/51 , C12N1/21 , C12N15/12 , C07K14/435 , C12N15/00
CPC分类号: C07K14/51 , A61L24/043 , A61L27/227 , A61K38/00
摘要: Purified BMP-2 proteins and processes for producing them are disclosed. They may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
摘要翻译: 公开了纯化的BMP-2蛋白质及其制备方法。 它们可用于治疗骨和软骨缺损以及伤口愈合和相关组织修复。
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公开(公告)号:US5108922A
公开(公告)日:1992-04-28
申请号:US561496
申请日:1990-07-31
申请人: Elizabeth A. Wang , John M. Wozney , Vicki Rosen
发明人: Elizabeth A. Wang , John M. Wozney , Vicki Rosen
CPC分类号: C07K14/51 , A61L24/043 , A61L27/227 , A61K38/00
摘要: Purified BMP-1 proteins and processes for producing them are disclosed. They may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
摘要翻译: 公开了纯化的BMP-1蛋白质及其生产方法。 它们可用于治疗骨和软骨缺损以及伤口愈合和相关组织修复。
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公开(公告)号:US5013649A
公开(公告)日:1991-05-07
申请号:US179100
申请日:1988-04-08
申请人: Elizabeth A. Wang , John M. Wozney , Vicki Rosen
发明人: Elizabeth A. Wang , John M. Wozney , Vicki Rosen
CPC分类号: C07K14/51 , A61L24/043 , A61L27/227 , A61K38/00
摘要: Purified BMP-2 proteins and processes for producing them are disclosed. They may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
摘要翻译: 公开了纯化的BMP-2蛋白质及其生产方法。 它们可用于治疗骨和软骨缺损以及伤口愈合和相关组织修复。
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公开(公告)号:US06207813B1
公开(公告)日:2001-03-27
申请号:US09189157
申请日:1998-11-09
IPC分类号: C07H2104
CPC分类号: C12N15/85 , A61K38/00 , A61L24/043 , A61L27/227 , C07K14/51 , Y10S530/84 , C08L89/00
摘要: Purified BMP-6 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
摘要翻译: 公开了纯化的BMP-6蛋白质及其生产方法。 蛋白质可用于治疗骨和/或软骨缺损以及伤口愈合和相关组织修复。
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公开(公告)号:US5141905A
公开(公告)日:1992-08-25
申请号:US438919
申请日:1989-11-17
IPC分类号: A61K20060101 , A61K38/00 , A61L24/04 , A61L27/22 , C07K20060101 , C07K14/51 , C12N20060101 , C12N15/85
CPC分类号: C12N15/85 , A61L24/043 , A61L27/227 , C07K14/51 , A61K38/00
摘要: Purified BMP-7 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartlage defects and in wound healing and related tissue repair.
摘要翻译: 公开了纯化的BMP-7蛋白质及其生产方法。 蛋白质可用于治疗骨和/或卡氏缺陷以及伤口愈合和相关组织修复。
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公开(公告)号:US5635373A
公开(公告)日:1997-06-03
申请号:US469935
申请日:1995-06-06
CPC分类号: C12N15/85 , A61L24/043 , A61L27/227 , C07K14/51 , A61K38/00 , C12N2800/108 , C12N2840/20
摘要: Purified BMP-5 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
摘要翻译: 公开了纯化的BMP-5蛋白质及其生产方法。 蛋白质可用于治疗骨和/或软骨缺损以及伤口愈合和相关组织修复。
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