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公开(公告)号:US07910708B2
公开(公告)日:2011-03-22
申请号:US12091020
申请日:2006-10-19
申请人: Emma Campbell , Sofia Parveen , Joe Buechler , Gunars Valkirs
发明人: Emma Campbell , Sofia Parveen , Joe Buechler , Gunars Valkirs
IPC分类号: C12P21/08 , C07K16/00 , A61K39/395 , A61K39/00
CPC分类号: C07K16/244 , A61K38/012 , A61K2039/505 , A61K2039/507 , C07K2317/21 , C07K2317/76 , C07K2317/92 , C12N15/81 , C12P21/02 , Y10S514/853
摘要: The present invention relates to human anti-IL-13 binding molecules, particularly antibodies, and to methods for using anti-IL-13 antibody molecules in diagnosis or treatment of IL-13 related disorders, such as asthma, atopic dermatitis, allergic rhinitis, fibrosis, inflammatory bowel disease and Hodgkin's lymphoma.
摘要翻译: 本发明涉及人抗IL-13结合分子,特别是抗体,以及在诊断或治疗IL-13相关疾病如哮喘,特应性皮炎,过敏性鼻炎, 纤维化,炎性肠病和霍奇金淋巴瘤。
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公开(公告)号:US20080267959A1
公开(公告)日:2008-10-30
申请号:US12091020
申请日:2006-10-19
申请人: Emma Campbell , Sofia Parveen , Joe Buechler , Gunars Valkirs
发明人: Emma Campbell , Sofia Parveen , Joe Buechler , Gunars Valkirs
IPC分类号: A61K39/395 , C07K16/24 , A61P11/06
CPC分类号: C07K16/244 , A61K38/012 , A61K2039/505 , A61K2039/507 , C07K2317/21 , C07K2317/76 , C07K2317/92 , C12N15/81 , C12P21/02 , Y10S514/853
摘要: The present invention relates to human anti-IL-13 binding molecules, particularly antibodies, and to methods for using anti-IL-13 antibody molecules in diagnosis or treatment of IL-13 related disorders, such as asthma, atopic dermatitis, allergic rhinitis, fibrosis, inflammatory bowel disease and Hodgkin's lymphoma.
摘要翻译: 本发明涉及人抗IL-13结合分子,特别是抗体,以及在诊断或治疗IL-13相关疾病如哮喘,特应性皮炎,过敏性鼻炎, 纤维化,炎性肠病和霍奇金淋巴瘤。
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公开(公告)号:US20110091458A1
公开(公告)日:2011-04-21
申请号:US12975667
申请日:2010-12-22
申请人: Emma CAMPBELL , Sofia Parveen , Joe Buechler , Gunars Valkirs
发明人: Emma CAMPBELL , Sofia Parveen , Joe Buechler , Gunars Valkirs
CPC分类号: C07K16/244 , A61K38/012 , A61K2039/505 , A61K2039/507 , C07K2317/21 , C07K2317/76 , C07K2317/92 , C12N15/81 , C12P21/02 , Y10S514/853
摘要: The present invention relates to human anti-IL-13 binding molecules, particularly antibodies, and to methods for using anti-IL-13 antibody molecules in diagnosis or treatment of IL-13 related disorders, such as asthma, atopic dermatitis, allergic rhinitis, fibrosis, inflammatory bowel disease and Hodgkin's lymphoma.
摘要翻译: 本发明涉及人抗IL-13结合分子,特别是抗体,以及在诊断或治疗IL-13相关疾病如哮喘,特应性皮炎,过敏性鼻炎, 纤维化,炎性肠病和霍奇金淋巴瘤。
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公开(公告)号:US08580260B2
公开(公告)日:2013-11-12
申请号:US12975667
申请日:2010-12-22
IPC分类号: A61K39/395 , A61P11/06 , C07K14/47 , C07K16/24 , C07K7/06
CPC分类号: C07K16/244 , A61K38/012 , A61K2039/505 , A61K2039/507 , C07K2317/21 , C07K2317/76 , C07K2317/92 , C12N15/81 , C12P21/02 , Y10S514/853
摘要: The present invention relates to human anti-IL-13 binding molecules, particularly antibodies, and to methods for using anti-IL-13 antibody molecules in diagnosis or treatment of IL-13 related disorders, such as asthma, atopic dermatitis, allergic rhinitis, fibrosis, inflammatory bowel disease and Hodgkin's lymphoma.
摘要翻译: 本发明涉及人抗IL-13结合分子,特别是抗体,以及在诊断或治疗IL-13相关疾病如哮喘,特应性皮炎,过敏性鼻炎, 纤维化,炎性肠病和霍奇金淋巴瘤。
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公开(公告)号:US09650438B2
公开(公告)日:2017-05-16
申请号:US14629587
申请日:2015-02-24
CPC分类号: C07K16/244 , A61K38/012 , A61K2039/505 , A61K2039/507 , C07K2317/21 , C07K2317/76 , C07K2317/92 , C12N15/81 , C12P21/02 , Y10S514/853
摘要: The present invention relates to human anti-IL-13 binding molecules, particularly antibodies, and to methods for using anti-IL-13 antibody molecules in diagnosis or treatment of IL-13 related disorders, such as asthma, atopic dermatitis, allergic rhinitis, fibrosis, inflammatory bowel disease and Hodgkin's lymphoma.
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公开(公告)号:US20170101467A9
公开(公告)日:2017-04-13
申请号:US14629587
申请日:2015-02-24
IPC分类号: C07K16/24
CPC分类号: C07K16/244 , A61K38/012 , A61K2039/505 , A61K2039/507 , C07K2317/21 , C07K2317/76 , C07K2317/92 , C12N15/81 , C12P21/02 , Y10S514/853
摘要: The present invention relates to human anti-IL-13 binding molecules, particularly antibodies, and to methods for using anti-IL-13 antibody molecules in diagnosis or treatment of IL-13 related disorders, such as asthma, atopic dermatitis, allergic rhinitis, fibrosis, inflammatory bowel disease and Hodgkin's lymphoma.
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公开(公告)号:US20150259411A1
公开(公告)日:2015-09-17
申请号:US14629587
申请日:2015-02-24
IPC分类号: C07K16/24
CPC分类号: C07K16/244 , A61K38/012 , A61K2039/505 , A61K2039/507 , C07K2317/21 , C07K2317/76 , C07K2317/92 , C12N15/81 , C12P21/02 , Y10S514/853
摘要: The present invention relates to human anti-IL-13 binding molecules, particularly antibodies, and to methods for using anti-IL-13 antibody molecules in diagnosis or treatment of IL-13 related disorders, such as asthma, atopic dermatitis, allergic rhinitis, fibrosis, inflammatory bowel disease and Hodgkin's lymphoma.
摘要翻译: 本发明涉及人抗IL-13结合分子,特别是抗体,以及在诊断或治疗IL-13相关疾病如哮喘,特应性皮炎,过敏性鼻炎, 纤维化,炎性肠病和霍奇金淋巴瘤。
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公开(公告)号:US08992916B2
公开(公告)日:2015-03-31
申请号:US14044314
申请日:2013-10-02
IPC分类号: A61K39/395 , C07K16/24 , A61K39/00
CPC分类号: C07K16/244 , A61K38/012 , A61K2039/505 , A61K2039/507 , C07K2317/21 , C07K2317/76 , C07K2317/92 , C12N15/81 , C12P21/02 , Y10S514/853
摘要: The present invention relates to human anti-IL-13 binding molecules, particularly antibodies, and to methods for using anti-IL-13 antibody molecules in diagnosis or treatment of IL-13 related disorders, such as asthma, atopic dermatitis, allergic rhinitis, fibrosis, inflammatory bowel disease and Hodgkin's lymphoma.
摘要翻译: 本发明涉及人抗IL-13结合分子,特别是抗体,以及在诊断或治疗IL-13相关疾病如哮喘,特应性皮炎,过敏性鼻炎, 纤维化,炎性肠病和霍奇金淋巴瘤。
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公开(公告)号:US07189515B2
公开(公告)日:2007-03-13
申请号:US10149737
申请日:2000-12-06
申请人: Joe Buechler , Gunars Valkirs , Jeff Gray , Nils Lonberg
发明人: Joe Buechler , Gunars Valkirs , Jeff Gray , Nils Lonberg
IPC分类号: G01N33/543
CPC分类号: C07K16/18 , C07K16/244 , C07K2317/21 , C07K2317/55 , G01N33/543 , Y02A50/55 , Y02A50/58 , Y10S435/962 , Y10S435/973 , Y10S436/809
摘要: The invention provides in vitro methods of detection using human antibodies. The methods are particularly useful for analyzing human samples containing HAMA or heterophilic antibodies. A human antibody can bind to an analyte in such samples without binding to HAMA or heterophilic antibodies present in the samples. The methods can be effected using a sandwich format among others.
摘要翻译: 本发明提供使用人抗体的体外检测方法。 该方法对于分析含有HAMA或异嗜性抗体的人类样品特别有用。 人抗体可以结合这样的样品中的分析物而不与样品中存在的HAMA或异嗜性抗体结合。 这些方法可以使用夹心形式等来实现。
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公开(公告)号:US20080039338A1
公开(公告)日:2008-02-14
申请号:US11685068
申请日:2007-03-12
申请人: Joe Buechler , Gunars Valkirs , Jeff Gray , Nils Lonberg
发明人: Joe Buechler , Gunars Valkirs , Jeff Gray , Nils Lonberg
IPC分类号: G01N33/543 , C40B30/04
CPC分类号: C07K16/18 , C07K16/244 , C07K2317/21 , C07K2317/55 , G01N33/543 , Y02A50/58 , Y10S435/962 , Y10S435/973 , Y10S436/809
摘要: The invention provides in vitro methods of detection using human antibodies. The methods are particularly useful for analyzing human samples containing HAMA or heterophilic antibodies. A human antibody can bind to an analyte in such samples without binding to HAMA or heterophilic antibodies present in the sample. The methods can be effected using a sandwich format among others.
摘要翻译: 本发明提供使用人抗体的体外检测方法。 该方法对于分析含有HAMA或异嗜性抗体的人类样品特别有用。 人抗体可以结合到这些样品中的分析物而不与样品中存在的HAMA或异嗜性抗体结合。 这些方法可以使用夹心形式等来实现。
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