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公开(公告)号：US20160025716A1
公开(公告)日：2016-01-28
申请号：US14844468
申请日：2015-09-03
Inventor： Jack Coleman , Elazar Rabbani , Jannis Stavrianopoulos , Praveen Pande
IPC: G01N33/533 , C12Q1/68 , G01N33/58
CPC classification number: C07H21/00 , C07D219/08 , C07D405/14 , C07D491/22 , C07H21/04 , C09B11/00 , C09B11/08 , C09B11/24 , C09B57/02 , C12Q1/68 , C12Q1/6818 , G01N33/533 , G01N33/582
Abstract: Provided are compounds comprising two DNA supramolecular binding molecules covalently joined by a linker group. Also provided are multisignal labeling reagents comprising (i) an oligomer of nucleotides or nucleotide analogs; (ii) a DNA supramolecular binding molecule noncovalently bound to the oligomer; and (iii) a first reactive group or a first partner of a first binding pair covalently bound to the oligomer. Additionally provided are methods of producing multisignal labeling reagents.
Abstract translation: 提供了包含由连接基共价连接的两个DNA超分子结合分子的化合物。 还提供了多信号标记试剂，其包含（i）核苷酸或核苷酸类似物的寡聚物; （ii）非共价结合寡聚体的DNA超分子结合分子; 和（iii）与低聚物共价结合的第一结合对的第一反应性基团或第一配偶体。 另外提供了生产多信号标记试剂的方法。
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公开(公告)号：US09884889B2
公开(公告)日：2018-02-06
申请号：US14844468
申请日：2015-09-03
Applicant: Enzo Life Science, Inc.
Inventor： Jack Coleman , Elazar Rabbani , Jannis Stavrianopoulos , Praveen Pande
IPC: C07H19/04 , C07H21/00 , C07D219/08 , C07D491/22 , C07H21/04 , C09B11/08 , C09B11/24 , C12Q1/68 , C07D405/14 , C09B11/00 , C09B57/02 , G01N33/533 , G01N33/58
CPC classification number: C07H21/00 , C07D219/08 , C07D405/14 , C07D491/22 , C07H21/04 , C09B11/00 , C09B11/08 , C09B11/24 , C09B57/02 , C12Q1/68 , C12Q1/6818 , G01N33/533 , G01N33/582
Abstract: Provided are compounds comprising two DNA supramolecular binding molecules covalently joined by a linker group. Also provided are multisignal labeling reagents comprising (i) an oligomer of nucleotides or nucleotide analogs; (ii) a DNA supramolecular binding molecule noncovalently bound to the oligomer; and (iii) a first reactive group or a first partner of a first binding pair covalently bound to the oligomer. Additionally provided are methods of producing multisignal labeling reagents.
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Patent Agency Ranking
公开(公告)号：US20200270297A1
公开(公告)日：2020-08-27
申请号：US16830483
申请日：2020-03-26
Applicant: Enzo Life Science, Inc.
Inventor： Jack Coleman , Elazar Rabbani , Jannis Stavrianopoulos , Praveen Pande
IPC: C07H21/00 , C07D219/08 , C07D491/22 , C07H21/04 , C09B11/08 , C12Q1/6818 , C07D405/14 , C09B11/00 , C09B57/02 , C12Q1/68 , C09B11/24 , G01N33/533 , G01N33/58
Abstract: Provided are compounds comprising two DNA supramolecular binding molecules covalently joined by a linker group. Also provided are multisignal labeling reagents comprising (i) an oligomer of nucleotides or nucleotide analogs; (ii) a DNA supramolecular binding molecule noncovalently bound to the oligomer; and (iii) a first reactive group or a first partner of a first binding pair covalently bound to the oligomer. Additionally provided are methods of producing multisignal labeling reagents.
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公开(公告)号：US10647740B2
公开(公告)日：2020-05-12
申请号：US15850028
申请日：2017-12-21
Applicant: Enzo Life Science, Inc.
Inventor： Jack Coleman , Elazar Rabbani , Jannis Stavrianopoulos , Praveen Pande
IPC: C12Q1/68 , C07H21/00 , C07D219/08 , C07D491/22 , C07H21/04 , C09B11/08 , C12Q1/6818 , C07D405/14 , C09B11/00 , C09B57/02 , C09B11/24 , G01N33/533 , G01N33/58
Abstract: Provided are compounds comprising two DNA supramolecular binding molecules covalently joined by a linker group. Also provided are multisignal labeling reagents comprising (i) an oligomer of nucleotides or nucleotide analogs; (ii) a DNA supramolecular binding molecule noncovalently bound to the oligomer; and (iii) a first reactive group or a first partner of a first binding pair covalently bound to the oligomer. Additionally provided are methods of producing multisignal labeling reagents.
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公开(公告)号：US11028121B2
公开(公告)日：2021-06-08
申请号：US16830483
申请日：2020-03-26
Applicant: Enzo Life Science, Inc.
Inventor： Jack Coleman , Elazar Rabbani , Jannis Stavrianopoulos , Praveen Pande
IPC: C07H21/00 , C07D219/08 , C07D491/22 , C07H21/04 , C09B11/08 , C12Q1/6818 , C07D405/14 , C09B11/00 , C09B57/02 , C12Q1/68 , C09B11/24 , G01N33/533 , G01N33/58
Abstract: Provided are compounds comprising two DNA supramolecular binding molecules covalently joined by a linker group. Also provided are multisignal labeling reagents comprising (i) an oligomer of nucleotides or nucleotide analogs; (ii) a DNA supramolecular binding molecule noncovalently bound to the oligomer; and (iii) a first reactive group or a first partner of a first binding pair covalently bound to the oligomer. Additionally provided are methods of producing multisignal labeling reagents.
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公开(公告)号：US20180127456A1
公开(公告)日：2018-05-10
申请号：US15850028
申请日：2017-12-21
Inventor： Jack Coleman , Elazar Rabbani , Jannis Stavrianopoulos , Praveen Pande
IPC: C07H21/00 , G01N33/58 , C12Q1/6818 , C09B11/24 , G01N33/533 , C12Q1/68 , C09B57/02 , C07D219/08 , C07D405/14 , C09B11/08 , C07H21/04 , C07D491/22 , C09B11/00
CPC classification number: C07H21/00 , C07D219/08 , C07D405/14 , C07D491/22 , C07H21/04 , C09B11/00 , C09B11/08 , C09B11/24 , C09B57/02 , C12Q1/68 , C12Q1/6818 , G01N33/533 , G01N33/582
Abstract: Provided are compounds comprising two DNA supramolecular binding molecules covalently joined by a linker group. Also provided are multisignal labeling reagents comprising (i) an oligomer of nucleotides or nucleotide analogs; (ii) a DNA supramolecular binding molecule noncovalently bound to the oligomer; and (iii) a first reactive group or a first partner of a first binding pair covalently bound to the oligomer. Additionally provided are methods of producing multisignal labeling reagents.
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公开(公告)号：US20180127455A1
公开(公告)日：2018-05-10
申请号：US15849997
申请日：2017-12-21
Inventor： Jack Coleman , Elazar Rabbani , Jannis Stavrianopoulos , Praveen Pande
IPC: C07H21/00 , G01N33/58 , C12Q1/6818 , C09B11/24 , G01N33/533 , C12Q1/68 , C09B57/02 , C07D219/08 , C07D405/14 , C09B11/08 , C07H21/04 , C07D491/22 , C09B11/00
CPC classification number: C07H21/00 , C07D219/08 , C07D405/14 , C07D491/22 , C07H21/04 , C09B11/00 , C09B11/08 , C09B11/24 , C09B57/02 , C12Q1/68 , C12Q1/6818 , G01N33/533 , G01N33/582
Abstract: Provided are compounds comprising two DNA supramolecular binding molecules covalently joined by a linker group. Also provided are multisignal labeling reagents comprising (i) an oligomer of nucleotides or nucleotide analogs; (ii) a DNA supramolecular binding molecule noncovalently bound to the oligomer; and (iii) a first reactive group or a first partner of a first binding pair covalently bound to the oligomer. Additionally provided are methods of producing multisignal labeling reagents.
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