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公开(公告)号：US20050166679A1
公开(公告)日：2005-08-04
申请号：US11091607
申请日：2005-03-28
申请人： Eric Carlson , Oleg Kolosov , Leonid Matsiev , Laura Mazzola , Mikhail Spitkovsky , John Gallipeo
发明人： Eric Carlson , Oleg Kolosov , Leonid Matsiev , Laura Mazzola , Mikhail Spitkovsky , John Gallipeo
CPC分类号： G01N29/036 , B01J2219/00689 , B01J2219/00707 , G01G3/13 , G01N5/045 , G01N33/15 , G01N2291/0257
摘要： A method and apparatus for measurement of mass of small sample sizes. The method and apparatus is particularly adapted for providing microbalance measurement of solid materials as part of a combinatorial research program. The method and apparatus contemplate monitoring the response of a resonator holding a sample and correlating the response with mass change in the samples.
摘要翻译： 用于测量小样品量的质量的方法和装置。 该方法和装置特别适于提供固体材料的微量天平测量作为组合研究程序的一部分。 该方法和装置考虑监测保持样品的谐振器的响应并将响应与样本中的质量变化相关联。
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公开(公告)号：US06928877B2
公开(公告)日：2005-08-16
申请号：US10155207
申请日：2002-05-24
申请人： Eric D. Carlson , Oleg Kolosov , Leonid Matsiev , Laura T. Mazzola , Mikhail Spitkovsky , John Gallipeo
发明人： Eric D. Carlson , Oleg Kolosov , Leonid Matsiev , Laura T. Mazzola , Mikhail Spitkovsky , John Gallipeo
CPC分类号： G01N29/036 , B01J2219/00689 , B01J2219/00707 , G01G3/13 , G01N5/045 , G01N33/15 , G01N2291/0257
摘要： A method and apparatus for measurement of mass of small sample sizes. The method and apparatus is particularly adapted for providing microbalance measurement of solid materials as part of a combinatorial research program. The method and apparatus contemplate monitoring the response of a resonator holding a sample and correlating the response with mass change in the samples.
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公开(公告)号：US08592220B2
公开(公告)日：2013-11-26
申请号：US12447143
申请日：2007-10-26
申请人： H. Sam Bergh , Jason Wells , Victor Wong , John Gallipeo , Lynn Van Erden , Anthony F. Volpe , Jeffrey Maag
发明人： H. Sam Bergh , Jason Wells , Victor Wong , John Gallipeo , Lynn Van Erden , Anthony F. Volpe , Jeffrey Maag
IPC分类号： G01N1/10
CPC分类号： G01N31/10 , B01J19/0046 , B01J2219/00286 , B01J2219/00306 , B01J2219/00389 , B01J2219/00477 , B01J2219/00495 , B01J2219/00585 , B01J2219/00596 , B01J2219/00601 , B01J2219/00689 , B01J2219/00704 , B01J2219/00736 , B01J2219/00747 , C40B60/12
摘要： The present invention discloses an apparatus and method for rapid analysis of members of a combinatorial library. The apparatus includes a plurality of reactor vessels for containing individual library members, a fluid handling system that apportions a test fluid about equally between each of the vessels and a housing for enclosing the reactor vessels, the housing defining a pressure chamber, wherein the housing is configured to sustain a pressure substantially above atmospheric pressure. This allows for simultaneous screening of library members at high pressure by providing a small pressure differential on reactor components. The disclosed apparatus is especially useful for screening library members based on their ability to catalyze the conversion of fluid reactants.
摘要翻译： 本发明公开了一种用于快速分析组合图书馆成员的装置和方法。 该装置包括用于容纳单个文件库构件的多个反应堆容器，在每个容器之间大致相等地分配测试流体的流体处理系统和用于封闭反应堆容器的壳体，壳体限定压力室，其中壳体 被配置为维持基本上高于大气压的压力。 这允许通过在反应器组件上提供小的压差同时筛选高压力下的文库构件。 基于它们催化流体反应物转化的能力，所公开的装置对于筛选文库成员特别有用。
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公开(公告)号：US20100144539A1
公开(公告)日：2010-06-10
申请号：US12447143
申请日：2007-10-26
申请人： H. Sam Bergh , Jason Wells , Victor Wong , John Gallipeo , Lynn Van Erden , Anthony F. Volpe , Jeffrey Maag
发明人： H. Sam Bergh , Jason Wells , Victor Wong , John Gallipeo , Lynn Van Erden , Anthony F. Volpe , Jeffrey Maag
CPC分类号： G01N31/10 , B01J19/0046 , B01J2219/00286 , B01J2219/00306 , B01J2219/00389 , B01J2219/00477 , B01J2219/00495 , B01J2219/00585 , B01J2219/00596 , B01J2219/00601 , B01J2219/00689 , B01J2219/00704 , B01J2219/00736 , B01J2219/00747 , C40B60/12
摘要： The present invention discloses an apparatus and method for rapid analysis of members of a combinatorial library. The apparatus includes a plurality of reactor vessels for containing individual library members, a fluid handling system that apportions a test fluid about equally between each of the vessels and a housing for enclosing the reactor vessels, the housing defining a pressure chamber, wherein the housing is configured to sustain a pressure substantially above atmospheric pressure. This allows for simultaneous screening of library members at high pressure by providing a small pressure differential on reactor components. The disclosed apparatus is especially useful for screening library members based on their ability to catalyze the conversion of fluid reactants.
摘要翻译： 本发明公开了一种用于快速分析组合图书馆成员的装置和方法。 该装置包括用于容纳单个文件库构件的多个反应堆容器，在每个容器之间大致相等地分配测试流体的流体处理系统和用于封闭反应堆容器的壳体，壳体限定压力室，其中壳体 被配置为维持基本上高于大气压的压力。 这允许通过在反应器组件上提供小的压差同时筛选高压力下的文库构件。 基于它们催化流体反应物转化的能力，所公开的装置对于筛选文库成员特别有用。
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