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公开(公告)号：US20240123418A1
公开(公告)日：2024-04-18
申请号：US18279702
申请日：2022-03-04
Inventor： Andreas Mueller , Peter Kolb , Michael Dejmek , Max Christoph Schmid
CPC classification number: B01J19/0006 , B01J19/0046 , B01J19/0093 , G05D16/024 , B01J2219/00306 , B01J2219/00337 , B01J2219/00369 , B01J2219/00585 , B01J2219/00689 , B01J2219/00698 , B01J2219/00704 , B01J2219/00997
Abstract: The invention relates to an apparatus for analyzing reaction systems with a liquid phase (13) and a gas phase (15), the apparatus (1) comprising at least two tank reactors (3), a common feed line (5), a common drain line (25) for the liquid phase and a common drain line (21) for the gas phase, each tank reactor (3) being connected to the common feed line (5) by a supply line (7), to the common drain line (25) for the liquid phase by a liquid withdrawal line (27) and to the common drain line (21) for the gas phase by a gas withdrawal line (23), wherein the pressure in each tank reactor (3) is controlled by one of:
(a) a pressure control (31) in the common feed line (5);
(b) a pressure line (29) which is connected to the gas space of each tank reactor (3);
(c) a pressure control (31) in the common drain line (21) for the gas phase and a flow restrictor (33) in the common drain line (25) for the liquid phase or a pressure control (31) in the common drain line (25) for the liquid phase and a flow restrictor (33) in the common drain line (21) for the gas phase; or
(d) a pressure line (29) which enters into the common drain line (25) for the liquid phase or into the common drain line (21) for the gas phase.
The invention further relates to a process for analyzing reaction systems in such an apparatus.-
公开(公告)号：US20180272346A1
公开(公告)日：2018-09-27
申请号：US15926900
申请日：2018-03-20
Applicant: Massachusetts Institute of Technology
Inventor： Linda G. Griffith , David Trumper , Collin Edington , Gaurav Rohatgi , Duncan Freake , Luis Soenksen , Timothy Kassis , Mohan Brij Bhushan
CPC classification number: B01L3/502715 , B01J2219/00182 , B01J2219/00306 , B01J2219/00355 , B01J2219/00479 , B01J2219/00889 , B01J2219/00952 , B01L3/50273 , B01L3/502738 , B01L2200/0621 , B01L2300/0829 , B01L2300/0887 , B01L2400/0406 , B01L2400/0457 , B01L2400/0487 , B01L2400/0655 , B01L2400/086 , C12M23/04 , C12M23/16 , C12M23/42 , F04B19/006 , F04B23/06 , F04B43/043 , F04B43/12 , G01F23/263
Abstract: Fluidic multiwell bioreactors are provided as a microphysiological platform for in vitro investigation of multi-organ crosstalks with microbiome for an extended period of time of at least weeks and months. The platform has one or more improvements over existing bioreactors, including on-board pumping for pneumatically driven fluid flow, a redesigned spillway for self-leveling from source to sink, a non-contact built-in fluid level sensing device, precise control on fluid flow profile and partitioning, and facile reconfigurations such as daisy chaining and multilayer stacking. The platform supports the culture of multiple organs together with microbiome in a microphysiological, interacted systems, suitable for a wide range of biomedical applications including systemic toxicity studies and physiology-based pharmacokinetic and pharmacodynamic predictions. A process to fabricate the bioreactors is also provided.
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公开(公告)号：US20180111127A1
公开(公告)日：2018-04-26
申请号：US15525444
申请日：2015-11-09
Applicant: Chemspeed Technologies AG
Inventor： Rolf Gueller , Michael Schneider , Thomas Thaler , Markus Schindler
CPC classification number: B01L3/523 , B01J2219/00306 , B01L3/02 , B01L3/0289 , B01L2200/0605 , B01L2200/18 , B01L2300/046 , B01L2300/0672 , B01L2300/0832 , B01L2300/0838 , B01L2400/0406 , B01L2400/0478 , B65D13/02 , B65D47/10
Abstract: A container for taking up and dispensing a substance includes a glass tubule, a glass punch that slides adjustably in the glass tubule, forming a seal, and a glass sleeve closed on one side, in which the glass tubule is accommodated. The glass sleeve is shorter than the glass tubule, so that the glass tubule projects out of the glass sleeve. The glass punch is longer than the glass tubule and projects out of the glass tubule at the end situated outside of the glass sleeve. The glass punch does not fill the glass tubule completely, so that a substance chamber remains in the region of the end of the glass tubule situated within the glass sleeve.
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公开(公告)号：US20180093246A1
公开(公告)日：2018-04-05
申请号：US15833364
申请日：2017-12-06
Applicant: International Business Machines Corporation
Inventor： Evan Colgan , Alexey Y. Lvov , Stanislav Polonsky
CPC classification number: B01J19/0046 , B01J2219/00286 , B01J2219/00306 , B01J2219/00418 , B01J2219/00511 , B01J2219/00522 , B01J2219/00527 , B01J2219/00576 , B01J2219/00585 , B01J2219/00596 , B01J2219/00621 , B01J2219/00659 , B01J2219/00689 , B01J2219/00695 , B01J2219/00698 , B01J2219/00702 , B01L3/502 , B01L3/5027 , B01L2200/0684 , B01L2200/10 , B01L2300/024 , B01L2300/041 , B01L2300/0874 , C12Q1/6874
Abstract: Systems, computer program products, and methods for using a flow cell array are provided herein. A system includes at least one processor coupled to a memory and configured for delivering multiple items of chemical matter independently to multiple reaction sites of a flow cell array across multiple distinct instances of time; imaging multiple parallel chemical reactions at the multiple reaction sites of the flow cell array; and recording an emission from each of the multiple chemical reactions site.
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公开(公告)号：US20180044180A1
公开(公告)日：2018-02-15
申请号：US15554752
申请日：2016-02-08
Applicant: International Dioxcide, Inc.
Inventor： Adrian Alan BURKE , Scott C. GLYNN , William J. HULSMAN , Michael TROTTIER , Neil ANDRE , Randy D. BELISLE , Peter GARRISON
CPC classification number: C01B11/024 , B01J19/002 , B01J19/006 , B01J19/24 , B01J2219/00162 , B01J2219/00164 , B01J2219/00306 , C01B11/022 , C02F1/76 , E21B41/0007 , E21B43/124 , F15D1/02
Abstract: A method for treating water with chlorine dioxide wherein the reactor is contained inside of the water supply line being treated and an eductor is used to draw in the chemical precursors. The method offers facilitated chlorine dioxide (ClO 2) generation and safer operation over wider ClO2 mass flow capacity, thus offering a more adaptable system for CLO2 treatments. Noise reduction and ease-of-use versus traditional eductor-based ClO2 generators are additional benefits from using this method.
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Patent Agency Ranking
公开(公告)号：US20170121271A1
公开(公告)日：2017-05-04
申请号：US15342686
申请日：2016-11-03
Applicant: National University of Singapore
Inventor： Saif A. Khan , Swee Kun Yap
IPC: C07C209/36 , B01J8/04 , B01J19/24 , B01J8/06
CPC classification number: C07C209/36 , B01J8/0492 , B01J8/065 , B01J19/0046 , B01J19/0093 , B01J19/2425 , B01J2208/06 , B01J2219/00286 , B01J2219/00306 , B01J2219/00353 , B01J2219/00418 , B01J2219/00587 , B01J2219/0072 , B01J2219/00747 , B01J2219/00783 , B01J2219/00792 , B01J2219/00813 , B01J2219/00833 , B01J2219/00835 , B01J2219/0086 , B01J2219/00869 , B01J2219/00871 , B01J2219/00891 , B01J2219/009 , B01J2219/00997 , B01J2219/0254 , B01J2219/0277 , B01J2219/0295 , C07C211/46
Abstract: A one-to-many parallelized millireactor system capable of high throughput production in millireactors. Also disclosed is a method for carrying out multi-phase reactions.
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公开(公告)号：US09387451B2
公开(公告)日：2016-07-12
申请号：US14170845
申请日：2014-02-03
Applicant: International Business Machines Corporation
Inventor： Evan C. Colgan , Alexey Y. Lvov , Stanislav Polonsky
CPC classification number: B01J19/0046 , B01J2219/00286 , B01J2219/00306 , B01J2219/00418 , B01J2219/00511 , B01J2219/00522 , B01J2219/00527 , B01J2219/00576 , B01J2219/00585 , B01J2219/00596 , B01J2219/00621 , B01J2219/00659 , B01J2219/00689 , B01J2219/00695 , B01J2219/00698 , B01J2219/00702 , B01L3/502 , B01L3/5027 , B01L2200/0684 , B01L2200/10 , B01L2300/024 , B01L2300/041 , B01L2300/0874 , C12Q1/6874
Abstract: Apparatus and methods for using a flow cell array are provided herein. An apparatus includes an array comprising one or more pixels, wherein each of the one or more pixels comprises multiple reaction sites openings; a first set of one or more sub-surface channels, wherein each of the multiple reaction site openings is connected to a sub-surface channel from the first set of one or more sub-surface channels; a second set of two or more sub-surface channels; and multiple vias connecting each channel from the first set of one or more sub-surface channels to (i) a first sub-surface channel from the second set of two or more sub-surface channels and (ii) a second sub-surface channel from the second set of two or more sub-surface channels.
Abstract translation: 本文提供了使用流动池阵列的装置和方法。 一种装置包括包括一个或多个像素的阵列，其中所述一个或多个像素中的每一个包括多个反应位置开口; 第一组一个或多个子表面通道，其中所述多个反应位置开口中的每一个连接到来自所述第一组一个或多个子表面通道的子表面通道; 第二组两个或多个子表面通道; 以及多个通孔，其将来自所述第一组一个或多个子表面通道的每个通道连接到（i）来自所述第二组两个或多个子表面通道的第一子表面通道，以及（ii）第二子表面通道 从第二组两个或多个子表面通道。
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公开(公告)号：US20160102351A1
公开(公告)日：2016-04-14
申请号：US14973241
申请日：2015-12-17
Applicant: International Business Machines Corporation
Inventor： Evan C. Colgan , Alexey Y. Lvov , Stanislav Polonsky
IPC: C12Q1/68
CPC classification number: B01J19/0046 , B01J2219/00286 , B01J2219/00306 , B01J2219/00418 , B01J2219/00511 , B01J2219/00522 , B01J2219/00527 , B01J2219/00576 , B01J2219/00585 , B01J2219/00596 , B01J2219/00621 , B01J2219/00659 , B01J2219/00689 , B01J2219/00695 , B01J2219/00698 , B01J2219/00702 , B01L3/502 , B01L3/5027 , B01L2200/0684 , B01L2200/10 , B01L2300/024 , B01L2300/041 , B01L2300/0874 , C12Q1/6874
Abstract: Apparatus and methods for using a flow cell array are provided herein. A method includes delivering multiple items of chemical matter independently to multiple reaction sites of a flow cell array across multiple distinct instances of time; imaging multiple parallel chemical reactions at the multiple reaction sites of the flow cell array; and recording an emission from each of the multiple chemical reactions site.
Abstract translation: 本文提供了使用流动池阵列的装置和方法。 一种方法包括在多个不同的时间段内独立地将多个化学物质项目独立地提供给流动池阵列的多个反应位点; 在流动池阵列的多个反应位点成像多个平行的化学反应; 并记录来自多个化学反应位点的排放。
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9.发明申请METHOD FOR CLEANING PRODUCER GAS USING A MICROWAVE INDUCED PLASMA CLEANING DEVICE 有权使用微波诱导等离子体清洁装置清洁生产商气体的方法公开(公告)号：US20150368573A1
公开(公告)日：2015-12-24
申请号：US14842494
申请日：2015-09-01
Applicant: PHG Energy, LLC
Inventor： Deon John POTGIETER , Mark Oliver LOFTIN , Tom STANZIONE , Jeffrey Scott BROWN
CPC classification number: C10K3/008 , B01J8/001 , B01J8/002 , B01J8/008 , B01J8/0453 , B01J8/0457 , B01J8/0492 , B01J8/0496 , B01J19/245 , B01J2208/00061 , B01J2208/0007 , B01J2208/00212 , B01J2208/00442 , B01J2208/00495 , B01J2208/0061 , B01J2208/00752 , B01J2208/00761 , B01J2219/00306 , B01J2219/00495 , B01J2219/185 , C01B3/50 , C01B3/56 , C10K1/002 , C10K1/024 , C10K1/20 , C10K1/32 , C10K1/34 , C10K3/023
Abstract: A device and method for cleaning producer gas includes a filter bed chamber, a microwave chamber, a first catalytic chamber and a second catalytic chamber. The filter bed chamber comprises an inlet for carbon-based material and a spent carbon outlet. The microwave chamber comprises a permeable top and wave guides around the perimeter through which microwaves can be introduced into the device using magnetrons. The first catalytic chamber is connected to the microwave chamber, and the second catalytic chamber is connected to the first catalytic chamber. The method comprises using the device by filling the filter bed chamber with carbon-based material, introducing microwaves into the microwave chamber using the magnetrons and wave guides, dissociating heavy carbons entrained within the gas by passing the gas through carbon-based material in the filter bed chamber, the microwave chamber, the first catalytic chamber and the second catalytic chamber.
Abstract translation: 用于清洁发生器气体的装置和方法包括滤床室，微波室，第一催化室和第二催化室。 过滤床室包括用于碳基材料的入口和废碳出口。 微波室包括围绕周边的可渗透顶部和波导，微波可通过该波导引入到使用磁控管的装置中。 第一催化室连接到微波室，第二催化室连接到第一催化室。 该方法包括通过用碳基材料填充滤床室来使用该装置，使用磁控管和波导将微波引入微波室，通过使气体通过过滤器中的碳基材料来解离夹带在气体内的重碳 床室，微波室，第一催化室和第二催化室。
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公开(公告)号：US20150217257A1
公开(公告)日：2015-08-06
申请号：US14170845
申请日：2014-02-03
Applicant: International Business Machines Corporation
Inventor： Evan C. Colgan , Alexey Y. Lvov , Stanislav Polonsky
CPC classification number: B01J19/0046 , B01J2219/00286 , B01J2219/00306 , B01J2219/00418 , B01J2219/00511 , B01J2219/00522 , B01J2219/00527 , B01J2219/00576 , B01J2219/00585 , B01J2219/00596 , B01J2219/00621 , B01J2219/00659 , B01J2219/00689 , B01J2219/00695 , B01J2219/00698 , B01J2219/00702 , B01L3/502 , B01L3/5027 , B01L2200/0684 , B01L2200/10 , B01L2300/024 , B01L2300/041 , B01L2300/0874 , C12Q1/6874
Abstract: Apparatus and methods for using a flow cell array are provided herein. An apparatus includes an array comprising one or more pixels, wherein each of the one or more pixels comprises multiple reaction sites openings; a first set of one or more sub-surface channels, wherein each of the multiple reaction site openings is connected to a sub-surface channel from the first set of one or more sub-surface channels; a second set of two or more sub-surface channels; and multiple vias connecting each channel from the first set of one or more sub-surface channels to (i) a first sub-surface channel from the to second set of two or more sub-surface channels and (ii) a second sub-surface channel from the second set of two or more sub-surface channels.
Abstract translation: 本文提供了使用流动池阵列的装置和方法。 一种装置包括包括一个或多个像素的阵列，其中所述一个或多个像素中的每一个包括多个反应位置开口; 第一组一个或多个子表面通道，其中所述多个反应位置开口中的每一个连接到来自所述第一组一个或多个子表面通道的子表面通道; 第二组两个或多个子表面通道; 以及多个通孔，其将来自所述第一组一个或多个子表面通道的每个通道连接到（i）从所述至第二组两个或更多个子表面通道的第一子表面通道和（ii）第二子表面 来自第二组两个或多个子表面通道的通道。
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