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公开(公告)号：US08204607B2
公开(公告)日：2012-06-19
申请号：US11450148
申请日：2006-06-09
IPC分类号： A61N1/36
CPC分类号： A61N1/0531 , A61N1/0534 , A61N1/0553 , A61N1/36071 , A61N1/37211
摘要： The disclosure describes an implantable medical lead for delivering stimulation to a patient. Electrodes may be located on two or more surfaces of the lead to, for example, selectively deliver stimulation to one or more tissue layers within the patient. The lead may be implanted within or between intra-dermal, deep dermal, or subcutaneous tissue layers, and may be used to, for example, deliver peripheral nerve field stimulation to treat pain experienced by the patient at the site at which the lead is implanted. The lead may comprise a paddle lead or a multiple level lead, e.g., a lead having a plurality of flat or paddle shaped lead bodies arranged in substantially parallel planes. Further, the lead may include fixation structures on the distal end, proximal end, or both ends to prevent migration.
摘要翻译： 本公开描述了用于将刺激递送给患者的可植入医疗引线。 电极可以位于引线的两个或更多个表面上，以例如选择性地将刺激递送到患者体内的一个或多个组织层。 铅可以植入在真皮内，深层皮肤或皮下组织层之内或之间，并且可以用于例如递送周围神经域刺激，以治疗患者在植入铅的部位所经历的疼痛 。 引线可以包括桨引线或多级引线，例如具有布置在基本上平行的平面中的多个扁平或桨状引线的引线。 此外，引线可以包括远端，近端或两端的固定结构，以防止迁移。
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2.发明授权公开(公告)号：US08588914B2
公开(公告)日：2013-11-19
申请号：US11450127
申请日：2006-06-09
IPC分类号： A61N1/375
CPC分类号： A61N1/375 , A61N1/0504 , A61N1/0531 , A61N1/0534 , A61N1/0553 , A61N1/36071 , A61N1/3756
摘要： An implantable medical device (IMD) with a housing and electrodes on at least two surfaces of the housing is described. The surfaces may be, for example, opposed, substantially parallel surfaces, e.g., top and bottom surfaces. Location of electrodes on multiple surfaces of the housing may allow the IMD to deliver stimulation to a variety of tissues and with a variety of current field configurations. For example, the IMD may deliver peripheral nerve field stimulation (PNFS) to one or more tissue areas via electrodes selected from one or both of the surfaces to, for example, reduce the sensation of pain in a tissue area proximate to an implantation site of the IMD without targeting a specific nerve. The IMD may be implanted between or within intra-dermal, deep dermal, or subcutaneous layers of the tissue of the patient to deliver PNFS to any one or more of these layers.
摘要翻译： 描述了在壳体的至少两个表面上具有壳体和电极的可植入医疗装置（IMD）。 表面可以是例如相对的基本上平行的表面，例如顶部和底部表面。 电极在壳体的多个表面上的位置可以允许IMD将刺激递送到各种组织以及各种当前的现场配置。 例如，IMD可以通过选自一个或两个表面的电极将外周神经区域刺激（PNFS）递送到一个或多个组织区域，以例如减少接近植入部位的组织区域中的疼痛感觉 IMD没有针对特定的神经。 IMD可以植入在患者组织的真皮内，深层皮肤或皮下层之间或内，以将PNFS递送到这些层中的任何一个或多个层。
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公开(公告)号：US08644941B2
公开(公告)日：2014-02-04
申请号：US11450144
申请日：2006-06-09
申请人： Ethan A. Rooney , Carl D. Wahlstrand , Gary W. King , Thomas E. Cross, Jr. , Jeffrey S. Evanson , Kenneth T. Heruth , Paul W. Wacnik
发明人： Ethan A. Rooney , Carl D. Wahlstrand , Gary W. King , Thomas E. Cross, Jr. , Jeffrey S. Evanson , Kenneth T. Heruth , Paul W. Wacnik
IPC分类号： A61N1/34
CPC分类号： A61N1/36071 , A61N1/0531 , A61N1/0534 , A61N1/0553 , A61N1/0558 , A61N1/36021 , A61N1/37205 , A61N1/37211 , A61N1/375 , A61N1/3756
摘要： Delivery of peripheral nerve field stimulation (PNFS) in combination with one or more other therapies is described. The other therapy delivered in combination with PNFS may be, for example, a different type of neurostimulation, such as spinal cord stimulation (SCS), or a drug. PNFS and the other therapy may be delivered simultaneously, in an alternating fashion, according to a schedule, and/or selectively, e.g., in response to a request received from a patient or clinician. A combination therapy that includes PNFS may be able to more completely address complex or multifocal pain than would be possible through delivery of either PNFS or other therapies alone. Further, the combination of PNFS with one or more other therapies may reduce the likelihood that neural accommodation will impair the perceived effectiveness PNFS or the other therapies.
摘要翻译： 描述了外周神经区域刺激（PNFS）与一种或多种其他疗法的结合。 与PNFS组合递送的另一疗法可以是例如不同类型的神经刺激，例如脊髓刺激（SCS）或药物。 PNFS和其他治疗可以根据时间表以交替方式同时递送，和/或选择性地，例如响应于从患者或临床医生接收到的请求。 包括PNFS的联合治疗可能能够更全面地解决复杂或多焦点疼痛，而不仅仅是通过传送PNFS或其他疗法来实现。 此外，PNFS与一种或多种其它疗法的组合可以降低神经调节可能损害所感知的有效性PNFS或其他疗法的可能性。
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公开(公告)号：US08620435B2
公开(公告)日：2013-12-31
申请号：US11450133
申请日：2006-06-09
申请人： Ethan A. Rooney , Carl D. Wahlstrand , Gary W. King , Thomas E. Cross, Jr. , Jeffrey S. Evanson , Kenneth T. Heruth , Paul W. Wacnik
发明人： Ethan A. Rooney , Carl D. Wahlstrand , Gary W. King , Thomas E. Cross, Jr. , Jeffrey S. Evanson , Kenneth T. Heruth , Paul W. Wacnik
IPC分类号： A61N1/34
CPC分类号： A61N1/36021 , A61M5/14 , A61M5/142 , A61M2205/054 , A61N1/0531 , A61N1/0534 , A61N1/0553 , A61N1/0558 , A61N1/36017 , A61N1/36071 , A61N1/37211 , A61N1/375
摘要： Delivery of peripheral nerve field stimulation (PNFS) in combination with one or more other therapies is described. The other therapy delivered in combination with PNFS may be, for example, a different type of neurostimulation, such as spinal cord stimulation (SCS), or a drug. PNFS and the other therapy may be delivered simultaneously, in an alternating fashion, according to a schedule, and/or selectively, e.g., in response to a request received from a patient or clinician. A combination therapy that includes PNFS may be able to more completely address complex or multifocal pain than would be possible through delivery of either PNFS or other therapies alone. Further, the combination of PNFS with one or more other therapies may reduce the likelihood that neural accommodation will impair the perceived effectiveness PNFS or the other therapies.
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公开(公告)号：US20100324570A1
公开(公告)日：2010-12-23
申请号：US12869891
申请日：2010-08-27
IPC分类号： A61B17/00
CPC分类号： A61M25/0662 , A61N1/0551 , A61N1/0553 , A61N1/372 , A61N1/37205 , A61N1/3756
摘要： The disclosure describes an introducer for facilitating implantation of therapy elements into a patient. The introducer has an elongated body that defines a lumen for advancement of a therapy element to an implant site, and includes a curved portion medially located between substantially straight proximal and distal portions. As an example, the shape of the introducer may allow a clinician to more easily, and without substantially damaging surrounding tissue, find the correct tissue depth and follow that tissue depth to the implant site. For example, the introducer may facilitate implantation of a therapy element within or between desired layers of tissue of the patient. In some embodiments, fluid may be injected through the introducer to create a space within the tissue to implant the therapy element. Fluid may also be evacuated through the introducer prior to implantation.
摘要翻译： 本公开描述了一种用于促进将治疗元件植入患者体内的导引器。 引导器具有限定用于使治疗元件前进到植入部位的内腔的细长主体，并且包括中间位于基本上直的近端部分和远端部分之间的弯曲部分。 作为示例，引导器的形状可以允许临床医生更容易地且不会基本上损伤周围的组织，找到正确的组织深度并且将该组织深度跟随到植入部位。 例如，导引器可以有助于将治疗元件植入患者组织的期望的层之内或之间。 在一些实施例中，流体可以通过导引器注入，以在组织内产生植入治疗元件的空间。 在植入之前，流体也可以通过引入器排空。
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公开(公告)号：US07792591B2
公开(公告)日：2010-09-07
申请号：US11450147
申请日：2006-06-09
CPC分类号： A61M25/0662 , A61N1/0551 , A61N1/0553 , A61N1/372 , A61N1/37205 , A61N1/3756
摘要： The disclosure describes an introducer for facilitating implantation of therapy elements into a patient. The introducer has an elongated body that defines a lumen for advancement of a therapy element to an implant site, and includes a curved portion medially located between substantially straight proximal and distal portions. As an example, the shape of the introducer may allow a clinician to more easily, and without substantially damaging surrounding tissue, find the correct tissue depth and follow that tissue depth to the implant site. For example, the introducer may facilitate implantation of a therapy element within or between desired layers of tissue of the patient. In some embodiments, fluid may be injected through the introducer to create a space within the tissue to implant the therapy element. Fluid may also be evacuated through the introducer prior to implantation.
摘要翻译： 本公开描述了一种用于促进将治疗元件植入患者体内的导引器。 引导器具有限定用于使治疗元件前进到植入部位的内腔的细长主体，并且包括中间位于基本上直的近端部分和远端部分之间的弯曲部分。 作为示例，引导器的形状可以允许临床医生更容易地且不会基本上损伤周围的组织，找到正确的组织深度并且将该组织深度跟随到植入部位。 例如，导引器可以有助于将治疗元件植入患者组织的期望的层之内或之间。 在一些实施例中，流体可以通过导引器注入，以在组织内产生植入治疗元件的空间。 在植入之前，流体也可以通过引入器排空。
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公开(公告)号：US09084872B2
公开(公告)日：2015-07-21
申请号：US12869891
申请日：2010-08-27
CPC分类号： A61M25/0662 , A61N1/0551 , A61N1/0553 , A61N1/372 , A61N1/37205 , A61N1/3756
摘要： The disclosure describes an introducer for facilitating implantation of therapy elements into a patient. The introducer has an elongated body that defines a lumen for advancement of a therapy element to an implant site, and includes a curved portion medially located between substantially straight proximal and distal portions. As an example, the shape of the introducer may allow a clinician to more easily, and without substantially damaging surrounding tissue, find the correct tissue depth and follow that tissue depth to the implant site. For example, the introducer may facilitate implantation of a therapy element within or between desired layers of tissue of the patient. In some embodiments, fluid may be injected through the introducer to create a space within the tissue to implant the therapy element. Fluid may also be evacuated through the introducer prior to implantation.
摘要翻译： 本公开描述了一种用于促进将治疗元件植入患者体内的导引器。 引导器具有限定用于使治疗元件前进到植入部位的内腔的细长主体，并且包括中间位于基本上直的近端部分和远端部分之间的弯曲部分。 作为示例，引导器的形状可以允许临床医生更容易地且不会基本上损伤周围的组织，找到正确的组织深度并且将该组织深度跟随到植入部位。 例如，导引器可以有助于将治疗元件植入患者组织的期望的层之内或之间。 在一些实施例中，流体可以通过导引器注入，以在组织内产生植入治疗元件的空间。 在植入之前，流体也可以通过引入器排空。
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