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公开(公告)号：US20210079451A1
公开(公告)日：2021-03-18
申请号：US17031383
申请日：2020-09-24
Applicant: Exact Sciences Development Company, LLC
Inventor： Hatim Allawi , Graham P. Lidgard , Brian Aizenstein , Tamara J. Sander , Maria Giakoumopoulos , Michael W. Kaiser , Melissa M. Gray , Abram Michael Vaccaro
IPC: C12Q1/6806 , C12Q1/686 , C12N15/10 , C12Q1/6837
Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.
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公开(公告)号：US10822638B2
公开(公告)日：2020-11-03
申请号：US15335111
申请日：2016-10-26
Applicant: EXACT SCIENCES DEVELOPMENT COMPANY, LLC
Inventor： Hatim Allawi , Graham P. Lidgard , Brian Aizenstein , Tamara J. Sander , Maria Giakoumopoulos , Michael W. Kaiser , Melissa M. Gray , Abram Michael Vaccaro
IPC: C12N15/00 , C12Q1/6806 , C12Q1/686 , C12N15/10 , C12Q1/6837
Abstract: Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA. The technology further provides methods for isolating DNA from blood or blood product samples, e.g., plasma samples.
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公开(公告)号：US20190330702A1
公开(公告)日：2019-10-31
申请号：US16460647
申请日：2019-07-02
Applicant: Exact Sciences Development Company, LLC , Mayo Foundation for Medical Education and Research
Inventor： Hatim Allawi , Graham P. Lidgard , Maria Giakoumopoulos , David A. Ahlquist , William R. Taylor , Douglas Mahoney
IPC: C12Q1/6886 , C12Q1/6806
Abstract: Provided herein is technology for lung neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of lung cancer.
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公开(公告)号：US20220136058A1
公开(公告)日：2022-05-05
申请号：US17297356
申请日：2019-11-26
Applicant: Exact Sciences Development Company, LLC , Mayo Foundation for Medical Education and Research
Inventor： Hatim Allawi , Graham P. Lidgard , Maria Giakoumopoulos , David A. Ahlquist , William R. Taylor , Douglas Mahoney
IPC: C12Q1/6886 , G01N33/574
Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting neoplasms such as lung cancer.
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Patent Agency Ranking
公开(公告)号：US20220106644A1
公开(公告)日：2022-04-07
申请号：US17424422
申请日：2020-01-24
Applicant: Mayo Foundation for Medical Education and Research , Exact Sciences Development Company, LLC
Inventor： William R. Taylor , John B. Kisiel , Douglas W. Mahoney , David A. Ahlquist , Hatim T. Allawi , Maria Giakoumopoulos
IPC: C12Q1/6886 , G16B30/10 , G16B35/20
Abstract: Provided herein is technology for endometrial cancer (EC) screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of endometrial cancer and various subtypes of endometrial cancer.
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公开(公告)号：US20220071605A1
公开(公告)日：2022-03-10
申请号：US17233199
申请日：2021-04-16
Applicant: Exact Sciences Development Company, LLC , Mayo Foundation for Medical Education and Research
Inventor： Robert F. Eisele , Michael E. Williams , Prasad G. Iyer , Paul Marrione , Hatim T. Allawi , Graham P. Lidgard , Maria Giakoumopoulos , William R. Taylor , Tracy C. Yab , Douglas W. Mahoney , John B. Kisiel , David A. Ahlquist
Abstract: The invention relates to cell sampling devices. In particular, the present invention relates to ingestible cell sampling devices for sampling cells in a subject, and methods of use for detecting abnormalities in a subject using the same. Provided herein is technology for neoplasia screening, and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of cancer.
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公开(公告)号：US20210262042A1
公开(公告)日：2021-08-26
申请号：US17314099
申请日：2021-05-07
Applicant: Exact Sciences Development Company, LLC , Mayo Foundation for Medical Education and Research
Inventor： Hatim Allawi , Graham P. Lidgard , Maria Giakoumopoulos , David A. Ahlquist , William R. Taylor , Douglas Mahoney
IPC: C12Q1/6886 , C12Q1/6806
Abstract: Provided herein is technology for lung neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of lung cancer.
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公开(公告)号：US11028447B2
公开(公告)日：2021-06-08
申请号：US16460647
申请日：2019-07-02
Applicant: Exact Sciences Development Company, LLC , Mayo Foundation for Medical Education and Research
Inventor： Hatim Allawi , Graham P. Lidgard , Maria Giakoumopoulos , David A. Ahlquist , William R. Taylor , Douglas Mahoney
IPC: C12Q1/6886 , C12Q1/6806
Abstract: Provided herein is technology for lung neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of lung cancer.
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公开(公告)号：US10385406B2
公开(公告)日：2019-08-20
申请号：US15471337
申请日：2017-03-28
Applicant: EXACT SCIENCES DEVELOPMENT COMPANY, LLC , Mayo Foundation for Medical Education and Research
Inventor： Hatim Allawi , Graham P. Lidgard , Maria Giakoumopoulos , David A. Ahlquist , William R. Taylor , Douglas Mahoney
IPC: C12Q1/6886 , C12Q1/6806 , A61K31/713
Abstract: Provided herein is technology for lung neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of lung cancer.
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