METHOD OF PRODUCING MICRONEEDLE ARRAY
    2.
    发明申请

    公开(公告)号:US20200376247A1

    公开(公告)日:2020-12-03

    申请号:US16997696

    申请日:2020-08-19

    Abstract: An object of the present invention is to provide a method of producing a microneedle array that enables concentration of a drug at needle tips of the microneedle array. According to the present invention, provided is a method of producing a microneedle array, including a step of filling a hydrophobic mold with a drug-containing solution to form a needle tip, and a step of filling the mold including the formed needle tip with a liquid which contains a water-soluble polymer or disaccharides to form a needle base and a sheet, in which the drug-containing solution contains 0.01 mg/mL to 5 mg/mL of a surfactant.

    MICRO-NEEDLE ARRAY DEVICE
    3.
    发明申请

    公开(公告)号:US20210244927A1

    公开(公告)日:2021-08-12

    申请号:US17243860

    申请日:2021-04-29

    Abstract: An object of the present invention is to provide a micro-needle array device that can have the needle part sufficiently dissolved. According to the present invention, there is provided a micro-needle array device including: a micro-needle array having a sheet part and a plurality of needle parts existing on the top face of the sheet part; and a pressing member for pressing a surface of the sheet part, the surface being on the opposite side of the surface having the needle parts, wherein the sheet part has a thickness of 0.1 to 0.6 mm, and an area A of a pressing face of the pressing member for pressing the sheet part of the micro-needle array and an area B of a region where the needle parts of the needle array exist, satisfy the formula: 0.3≤A/B≤0.75.

    TRANSDERMAL ABSORPTION SHEET AND METHOD OF MANUFACTURING TRANSDERMAL ABSORPTION SHEET
    5.
    发明申请
    TRANSDERMAL ABSORPTION SHEET AND METHOD OF MANUFACTURING TRANSDERMAL ABSORPTION SHEET 有权
    超吸收片和制造超吸收片的方法

    公开(公告)号:US20170036003A1

    公开(公告)日:2017-02-09

    申请号:US15299563

    申请日:2016-10-21

    Abstract: To provide a transdermal absorption sheet with which control of a dissolution rate and suppression of drug diffusion can be achieved, and a method of manufacturing the transdermal absorption sheet. A transdermal absorption sheet 100 is provided with a sheet portion 116, a plurality of frustum portions 114 that is disposed on the sheet portion 116, and needle portions 112 that are disposed on the frustum portions 114, each of the plurality of needle portions 112 includes a first layer 120 containing a drug and a second layer 122 not containing a drug, and at least one of the plurality of needle portions 112 contains an air bubble 124.

    Abstract translation: 提供可以实现对溶出速度的控制和抑制药物扩散的透皮吸收片,以及制造透皮吸收片的方法。 透皮吸收片100设置有片状部116,设置在片状部116上的多个截头圆锥部114和设置在截头圆锥部114上的针部112,多个针部112中的每一个包括 含有药物的第一层120和不含药物的第二层122,并且多个针部112中的至少一个包含气泡124。

    MICRONEEDLE ARRAY
    7.
    发明申请
    MICRONEEDLE ARRAY 审中-公开

    公开(公告)号:US20190111188A1

    公开(公告)日:2019-04-18

    申请号:US16212803

    申请日:2018-12-07

    Abstract: An object of the present invention is to provide a microneedle array which has strength of withstanding the impact at the time of puncture. According to the present invention, provided is a microneedle array including: a sheet; and a plurality of needles which are present on an upper surface of the sheet, in which the needles contain a water-soluble polymer, the sheet contains a water-soluble polymer, the sheet has a central portion, which is a region where the plurality of needles are formed, and an end portion, and an average film thickness of the end portion is smaller than an average film thickness of the central portion.

Patent Agency Ranking