公开(公告)号：US10739361B2

公开(公告)日：2020-08-11

申请号：US15861753

申请日：2018-01-04

Applicant: FUJIFILM Corporation

Inventor： Tatsuya Ishizaka ,  Haruyasu Nakatsugawa ,  Susumu Osawa ,  Shinya Sugimoto

IPC: G01N33/96 ,  C12Q1/34 ,  G01N33/50 ,  G01N33/48 ,  G01N33/49 ,  A61B5/15 ,  G01N1/10 ,  G01N33/66

Abstract: An object of the present invention is to provide a blood analysis method in which a high level of repeatability and reproducibility is achieved with respect to measurement values in a blood sample, and a blood test kit which is used for the blood analysis method. According to the present invention, a blood analysis method including a step of diluting a collected blood sample with a diluent solution; a step of quantitatively determining sodium ions in the diluent solution of the blood sample by using a solution containing β-galactosidase and at least one substrate which is convertible by β-galactosidase so as to determine a dilution factor from a normal value of serum and blood plasm sodium ions which are homeostatically present in the blood and the quantitative value of sodium ions; and a step of analyzing a concentration of a target component to be measured in the blood sample from the determined dilution factor and a measurement value of a concentration of the target component to be measured in the blood sample, in which the diluent solution is a diluent solution which does not contain sodium ions, is provided.

公开(公告)号：US10823745B2

公开(公告)日：2020-11-03

申请号：US15862700

申请日：2018-01-05

Applicant: FUJIFILM Corporation

Inventor： Seiji Yamashita ,  Haruyasu Nakatsugawa ,  Susumu Osawa ,  Shinya Sugimoto

IPC: A61B5/15 ,  B01L3/00 ,  G01N33/96 ,  G01N33/48 ,  G01N33/49 ,  G01N1/38

Abstract: An object of the present invention is to provide a blood test kit and a blood analysis method capable of performing a blood test with a small amount of blood at high accuracy by visualizing a volume of blood collection and keeping the volume constant. According to the present invention, a blood test kit including a diluent solution for diluting components of a blood sample; and at least one transparent container for storing the components of the blood sample and the diluent solution, in which at least one constituent component included in the blood test kit is marked with a graduation for measuring the components of the blood sample and a liquid volume of the diluent solution, is provided.

公开(公告)号：US10697870B2

公开(公告)日：2020-06-30

申请号：US15861238

申请日：2018-01-03

Applicant: FUJIFILM Corporation

Inventor： Hikaru Urano ,  Tatsuya Ishizaka ,  Haruyasu Nakatsugawa ,  Susumu Osawa ,  Shinya Sugimoto

IPC: A61B5/15 ,  B01L3/00 ,  G01N1/38 ,  G01N1/10 ,  G01N33/96 ,  G01N33/48 ,  G01N33/49

Abstract: An object is to provide a blood test kit and a blood analysis method capable of performing a blood test with a small amount of blood at high accuracy by visualizing a volume of blood collection and keeping the volume constant. Provided is a blood test kit for analyzing a concentration of a target component in a blood sample using a normal component homeostatically present in blood, the kit including: a blood collection instrument for collecting the blood sample; a diluent solution for diluting the collected blood sample; and a storing instrument for storing the diluted blood sample, in which the blood collection instrument is a capillary.

公开(公告)号：US10788478B2

公开(公告)日：2020-09-29

申请号：US15861875

申请日：2018-01-04

Applicant: FUJIFILM Corporation

Inventor： Hikaru Urano ,  Haruyasu Nakatsugawa ,  Susumu Osawa ,  Shinya Sugimoto

IPC: G01N33/49 ,  A61B5/15 ,  G01N1/10 ,  G01N33/96 ,  G01N33/48 ,  B01L3/00 ,  G01N1/38 ,  G01N33/66

Abstract: An object is to perform analysis of a target component contained in a small volume of blood sample at high accuracy using a normal component homeostatically present in blood. Provided is a blood test kit for analyzing a concentration of a target component in a blood sample by using a normal component homeostatically present in blood, the kit including: a diluent solution for diluting a blood sample; and a member selected from the group consisting of a first storing instrument in which the diluent solution is stored, a separating instrument for separating and recovering blood plasma from the blood sample diluted with the diluent solution, a holding instrument for holding the separating instrument, a second storing instrument for storing the recovered blood plasma, and a sealing instrument for keeping the stored blood plasma in the second storing instrument, in which an amount of the normal component which is derived from the member and may be contained in the diluent solution is defined.

公开(公告)号：US10746723B2

公开(公告)日：2020-08-18

申请号：US15861353

申请日：2018-01-03

Applicant: FUJIFILM Corporation

Inventor： Seiji Yamashita ,  Haruyasu Nakatsugawa ,  Susumu Osawa ,  Shinya Sugimoto

IPC: G01N33/48 ,  A61B5/15 ,  G01N33/487 ,  G01N1/28 ,  G01N33/49 ,  G01N1/00 ,  G01N1/38 ,  G01N33/66 ,  G01N33/96 ,  G01N1/10

Abstract: An object of the present invention is to provide a blood test kit of which a component in a small volume of blood can be mailed in a safe state by controlling the influence of the outside temperature during the mailing, and a highly accurate blood analysis method in which coefficient of variation of a measurement value is reduced. According to the present invention, a blood test kit including a diluent solution for diluting a blood sample; a separating means for recovering blood plasma components from the diluted blood sample; a container for storing the blood plasma components recovered from the diluted blood sample; and a cold insulation means for cold-insulating the container, is provided.