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    COMPOSITIONS FOR THE IMPROVED TREATMENT OF ACNE AND RELATED DISORDERS
    2.
    发明申请
    COMPOSITIONS FOR THE IMPROVED TREATMENT OF ACNE AND RELATED DISORDERS 审中-公开
    改善治疗ACNE和相关疾病的组合物

    公开(公告)号：US20140121188A1

    公开(公告)日：2014-05-01

    申请号：US14147376

    申请日：2014-01-03

    申请人： Foamix Ltd.

    发明人： Dov Tamarkin ,  Elana Gazal ,  Rita Keynan ,  Meir Eini ,  David Schuz

    IPC分类号： A61K31/65

    CPC分类号： A61K31/65 ,  A61K9/0014 ,  A61K9/06 ,  A61K9/122 ,  A61K47/06 ,  A61K47/10 ,  A61K47/12 ,  A61K47/24 ,  A61K47/44

    摘要： Methods of treatment and dosage regimes using hydrophobic gel or foam composition comprising a tetracycline antibiotic in treating or alleviating a disorder including, acne, acne related symptoms, a tetracycline antibiotic responsive acne related disorder, skin disorder caused by a bacteria, and a tetracycline antibiotic responsive sebaceous gland disease, P. acne bacteria associated disorders and other superficial infections, including skin infections wherein the foam composition or gel is administered topically to a target area on a subject having the disorder and wherein the target area comprises an area of skin.

    摘要翻译： 使用包含四环素抗生素的疏水性凝胶或泡沫组合物在治疗或缓解包括痤疮，痤疮相关症状，四环素抗生素反应性痤疮相关病症，由细菌引起的皮肤病，以及四环素抗生素反应性 皮肤腺病，P.痤疮细菌相关疾病和其他浅表感染，包括皮肤感染，其中泡沫组合物或凝胶局部施用于具有病症的受试者的靶区域，并且其中所述目标区域包括皮肤区域。

    DICARBOXYLIC ACID FOAMABLE VEHICLE AND PHARMACEUTICAL COMPOSITIONS THEREOF
    4.
    发明申请
    DICARBOXYLIC ACID FOAMABLE VEHICLE AND PHARMACEUTICAL COMPOSITIONS THEREOF 审中-公开
    二羧酸可燃性汽车及其药用组合物

    公开(公告)号：US20130189195A1

    公开(公告)日：2013-07-25

    申请号：US13796860

    申请日：2013-03-12

    申请人： Foamix Ltd.

    发明人： Dov Tamarkin ,  Doron Friedman ,  Tal Berman ,  Enbal Ziv ,  David Schuz

    IPC分类号： A61K9/12

    CPC分类号： A61K9/122 ,  A01N25/16 ,  A61K8/046 ,  A61K8/362 ,  A61K8/37 ,  A61K8/4993 ,  A61K8/86 ,  A61K9/0014 ,  A61Q19/00

    摘要： The present invention teaches a foamable pharmaceutical carrier comprising a benefit agent, selected from the group consisting of a dicarboxylic acid and a dicarboxylic acid ester; a stabilizer selected from the group consisting of at least one surface-active agent; at least one polymeric agent and mixtures thereof; a solvent selected from the group consisting of water, a hydrophilic solvent, a hydrophobic solvent, a potent solvent, a polar solvent, a silicone, an emollient, and mixtures thereof, wherein the benefit agent, stabilizer and solvent are selected to provide a composition that is substantially resistant to aging and to phase separation and or can substantially stabilize other active ingredients. The invention further relates to a foamable composition further containing a liquefied hydrocarbon gas propellant.

    摘要翻译： 本发明教导了一种可发泡药物载体，其包含选自二羧酸和二羧酸酯的有益剂; 选自由至少一种表面活性剂组成的组的稳定剂; 至少一种聚合物及其混合物; 选自水，亲水溶剂，疏水溶剂，有效溶剂，极性溶剂，硅氧烷，软化剂及其混合物的溶剂，其中选择有益剂，稳定剂和溶剂以提供组合物 其基本上耐老化和相分离，或基本上稳定其它活性成分。 本发明还涉及另外含有液化烃气体推进剂的可发泡组合物。

    SUBSTANTIALLY NON-AQUEOUS FOAMABLE PETROLATUM BASED PHARMACEUTICAL AND COSMETIC COMPOSITIONS AND THEIR USES
    7.
    发明申请
    SUBSTANTIALLY NON-AQUEOUS FOAMABLE PETROLATUM BASED PHARMACEUTICAL AND COSMETIC COMPOSITIONS AND THEIR USES 有权
    基于非水性可泡沫PETROLATUM的药物和化妆品组合物及其用途

    公开(公告)号：US20140248219A1

    公开(公告)日：2014-09-04

    申请号：US14189559

    申请日：2014-02-25

    申请人： Foamix Ltd.

    发明人： Dov Tamarkin ,  Doron Friedman ,  Enbal Ziv ,  Meir Eini ,  Tal Berman ,  Jorge Danziger ,  Rita Keynan ,  David Schuz

    IPC分类号： A61K9/12 ,  A61K47/06

    CPC分类号： A61K8/046 ,  A61K8/31 ,  A61K9/0014 ,  A61K9/107 ,  A61K9/122 ,  A61K47/06 ,  A61K2800/31 ,  A61Q19/00 ,  Y10S514/859

    摘要： The present invention relates to stable substantially non-aqueous, non-alcoholic, non-silicone, foamable carrier compositions comprising petrolatum or mixtures thereof, at least one foam agent, at least one propellant, and with and without the addition of an active agent. The formulations may contain a solvent substantially miscible therein. The present invention further provides a method of treating, alleviating or preventing a disorder of mammalian subject in need thereof, comprising administering the above-mentioned compositions to an afflicted target site of said mammalian subject.

    摘要翻译： 本发明涉及包含凡士林或其混合物，至少一种泡沫剂，至少一种推进剂，以及加入和不添加活性剂的稳定的基本上非水性，非醇，非硅氧烷，可发泡的载体组合物。 制剂可以含有其中基本上可混溶的溶剂。 本发明还提供了治疗，减轻或预防有此需要的哺乳动物受试者病症的方法，包括将上述组合物施用于所述哺乳动物受试者的受影响的靶位点。