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公开(公告)号：US11905299B2
公开(公告)日：2024-02-20
申请号：US17317041
申请日：2021-05-11
Applicant: Gilead Sciences, Inc.
Inventor： Elizabeth M. Bacon , Gayatri Balan , Chien-Hung Chou , Christopher T. Clark , Jeromy J. Cottell , Musong Kim , Thorsten A. Kirschberg , John O. Link , Gary Phillips , Scott D. Schroeder , Neil H. Squires , Kirk L. Stevens , James G. Taylor , William J. Watkins , Nathan E. Wright , Sheila M. Zipfel
IPC: C07D401/12 , C07D498/04 , C07D405/14 , C07D413/14 , C07D409/14 , C07D417/14 , C07D471/04 , C07D495/04 , C07D401/14 , C07B59/00
CPC classification number: C07D498/04 , C07B59/002 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D495/04 , C07B2200/05
Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
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公开(公告)号：US20210323922A1
公开(公告)日：2021-10-21
申请号：US17098171
申请日：2020-11-13
Applicant: Gilead Sciences, Inc.
Inventor： Evangelos Aktoudianakis , Todd Appleby , Aesop Cho , Zhimin Du , Michael Graupe , Juan A. Guerrero , Salman Y. Jabri , Lateshkumar Thakorlal Lad , Paulo A. Machicao Tello , Jonathan William Medley , Samuel E. Metobo , Prasenjit Kumar Mukherjee , Devan Naduthambi , Gregory Notte , Eric Q. Parkhill , Barton W. Phillips , Scott Preston Simonovich , Neil H. Squires , Chandrasekar Venkataramani , Peiyuan Wang , William J. Watkins , Jie Xu , Kin Shing Yang , Christopher Allen Ziebenhaus
IPC: C07D213/69 , A61K45/06 , A61K31/444 , C07D401/14 , A61K31/5377 , C07D213/85 , A61K31/44 , C07D213/30 , C07D295/088 , A61K31/4545 , C07D401/04 , A61K31/497 , C07D519/00 , C07D487/10 , C07D487/08 , C07D213/64 , C07D491/107 , C07D498/04 , C07D213/61 , C07D405/14
Abstract: Compounds according to formula (I), methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.
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公开(公告)号：US11066414B2
公开(公告)日：2021-07-20
申请号：US16717074
申请日：2019-12-17
Applicant: Gilead Sciences, Inc.
Inventor： Elizabeth M. Bacon , Gayatri Balan , Chien-Hung Chou , Christopher T. Clark , Jeromy J. Cottell , Musong Kim , Thorsten A. Kirschberg , John O. Link , Gary Phillips , Scott D. Schroeder , Neil H. Squires , Kirk L. Stevens , James G. Taylor , William J. Watkins , Nathan E. Wright , Sheila M. Zipfel
IPC: C07D401/14 , C07D498/04 , C07D405/14 , C07D413/14 , C07D401/12 , C07D409/14 , C07D417/14 , C07D471/04 , C07D495/04 , C07B59/00
Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
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公开(公告)号：US10710986B2
公开(公告)日：2020-07-14
申请号：US16274106
申请日：2019-02-12
Applicant: Gilead Sciences, Inc.
Inventor： Evangelos Aktoudianakis , Aesop Cho , Zhimin Du , Michael Graupe , Lateshkumar Thakorlal Lad , Paulo A. Machicao Tello , Jonathan William Medley , Samuel E. Metobo , Prasenjit Kumar Mukherjee , Devan Naduthambi , Eric Q. Parkhill , Barton W. Phillips , Scott Preston Simonovich , Neil H. Squires , Peiyuan Wang , William J. Watkins , Jie Xu , Kin Shing Yang , Christopher Allen Ziebenhaus
IPC: C07D403/14 , A61P31/20 , A61P35/02 , A61K31/496 , C07D519/00 , C07D241/20 , C07D487/10 , C07D405/14 , C07D487/08 , A61K31/497 , C07D491/107 , C07D241/18 , A61P35/00 , C07K16/28
Abstract: Compounds of Formula (I), methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.
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公开(公告)号：US20170008873A1
公开(公告)日：2017-01-12
申请号：US15199779
申请日：2016-06-30
Applicant: Gilead Sciences, Inc.
Inventor： Elizabeth M. Bacon , Gayatri Balan , Chien-Hung Chou , Christopher T. Clark , Jeromy J. Cottell , Musong Kim , Thorsten A. Kirschberg , John O. Link , Gary Phillips , Scott D. Schroeder , Neil H. Squires , Kirk L. Stevens , James G. Taylor , William J. Watkins , Nathan E. Wright , Sheila M. Zipfel
IPC: C07D401/12 , C07D413/12 , C07D413/14 , C07D417/14 , C07D409/14 , C07F7/08 , C07D453/02 , C07D401/14 , C07D405/14
CPC classification number: C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/14 , C07D453/02 , C07F7/0814
Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
Abstract translation: 本公开一般涉及Cot（癌症大阪甲状腺）的调节剂及其使用和制造方法。
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Patent Agency Ranking
公开(公告)号：US20240254137A1
公开(公告)日：2024-08-01
申请号：US18534800
申请日：2023-12-11
Applicant: Gilead Sciences, Inc.
Inventor： Elizabeth M. Bacon , Gayatri Balan , Chien-Hung Chou , Christopher T. Clark , Jeromy J. Cottell , Musong Kim , Thorsten A. Kirschberg , John O. Link , Gary Phillips , Scott D. Schroeder , Neil H. Squires , Kirk L. Stevens , James G. Taylor , William J. Watkins , Nathan E. Wright , Sheila M. Zipfel
IPC: C07D498/04 , C07B59/00 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D495/04
CPC classification number: C07D498/04 , C07B59/002 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D495/04 , C07B2200/05
Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
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公开(公告)号：US20230212155A1
公开(公告)日：2023-07-06
申请号：US18060934
申请日：2022-12-01
Applicant: Gilead Sciences, Inc.
Inventor： Evangelos Aktoudianakis , Aesop Cho , Zhimin Du , Michael Graupe , Lateshkumar Thakorlal Lad , Paulo A. Machicao Tello , Jonathan William Medley , Samuel E. Metobo , Prasenjit Kumar Mukherjee , Devan Naduthambi , Eric Q. Parkhill , Barton W. Phillips , Scott Preston Simonovich , Neil H. Squires , Peiyuan Wang , William J. Watkins , Jie Xu , Kin Shing Yang , Christopher Allen Ziebenhaus
IPC: C07D403/14 , A61P31/20 , A61P35/02 , A61K31/496 , C07D519/00 , C07D241/20 , C07D487/10 , C07D405/14 , C07D487/08 , A61K31/497 , C07D491/107 , C07D241/18 , A61P35/00
CPC classification number: C07D403/14 , A61P31/20 , A61P35/02 , A61K31/496 , C07D519/00 , C07D241/20 , C07D487/10 , C07D405/14 , C07D487/08 , A61K31/497 , C07D491/107 , C07D241/18 , A61P35/00 , C07K16/2818
Abstract: Compounds of Formula (I), methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.
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公开(公告)号：US10703733B2
公开(公告)日：2020-07-07
申请号：US16410457
申请日：2019-05-13
Applicant: Gilead Sciences, Inc.
Inventor： Hang Chu , Juan A. Guerrero , Anna E. Hurtley , Tae H. Hwang , Lan Jiang , Darryl Kato , Tetsuya Kobayashi , John E. Knox , Scott E. Lazerwith , Xiaofen Li , David W. Lin , Jonathan W. Medley , Michael L. Mitchell , Devan Naduthambi , Zachary Newby , Neil H. Squires , Vickie H. Tsui , Chandrasekar Venkataramani , William J. Watkins , Hong Yang
IPC: C07D513/08 , C07D267/20 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04 , C07D487/04 , C07D498/04 , A61K45/06
Abstract: The present disclosure generally relates to compounds and pharmaceutical compositions that may be used in methods of treating cancer.
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公开(公告)号：US20190352271A1
公开(公告)日：2019-11-21
申请号：US16410457
申请日：2019-05-13
Applicant: Gilead Sciences, Inc.
Inventor： Hang Chu , Juan A. Guerrero , Anna E. Hurtley , Tae H. Hwang , Lan Jiang , Darryl Kato , Tetsuya Kobayashi , John E. Knox , Scott E. Lazerwith , Xiaofen Li , David W. Lin , Jonathan W. Medley , Michael L. Mitchell , Devan Naduthambi , Zachary Newby , Neil H. Squires , Vickie H. Tsui , Chandrasekar Venkataramani , William J. Watkins , Hong Yang
IPC: C07D267/20 , C07D413/12 , C07D471/04 , C07D417/12 , C07D487/04 , C07D498/04 , C07D413/14
Abstract: The present disclosure generally relates to compounds and pharmaceutical compositions that may be used in methods of treating cancer.
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公开(公告)号：US10328053B2
公开(公告)日：2019-06-25
申请号：US15686499
申请日：2017-08-25
Applicant: Gilead Sciences, Inc.
Inventor： Jinfa Du , Joshua A. Kaplan , Thorsten A. Kirschberg , Tetsuya Kobayashi , Scott E. Lazerwith , Rick Andrew Lee , Jonathan William Medley , Michael L. Mitchell , Philip Anthony Morganelli , Hyung-Jung Pyun , Sophia L. Shevick , Neil H. Squires , William J. Watkins
IPC: A61K31/403 , A61P31/20 , A61K31/03 , A61K31/16 , C07D487/04 , C07D519/00 , A61K31/38 , A61K31/4192
Abstract: This application relates generally to certain substituted pyrrolizine compounds, and pharmaceutical compositions which inhibit HBV replication, and methods of making and using them.
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