公开(公告)号：US20180318415A1

公开(公告)日：2018-11-08

申请号：US15781351

申请日：2016-12-06

Applicant: GLAXOSMITHKLINE BIOLOGICALS, SA

Inventor： David BURKHART ,  Jay T. Evans ,  Hardeep OBEROI ,  Yvonne M. YORGENSEN

IPC: A61K39/39 ,  A61K39/145

CPC classification number: A61K39/39 ,  A61K9/5123 ,  A61K9/5161 ,  A61K31/7008 ,  A61K31/722 ,  A61K39/145 ,  A61K45/06 ,  A61K2039/541 ,  A61K2039/55555 ,  A61K2039/55572 ,  C12N2760/16134 ,  A61K2300/00

Abstract: The invention relates to a composition comprising solid lipid nanoparticles (SLNs), wherein the SLNs comprise an aminoalkyl glucosaminide phosphate (AGP).

公开(公告)号：US11274115B2

公开(公告)日：2022-03-15

申请号：US16330599

申请日：2017-09-05

Applicant: GLAXOSMITHKLINE BIOLOGICALS SA

Inventor： Helene G. Bazin-Lee ,  Jay T. Evans ,  David Burkhart ,  Michael Cochran ,  David A. Johnson

IPC: C07F9/6561

Abstract: This invention relates inter alia to novel imidazoquinoline derivatives and their use in therapy, particularly as vaccine adjuvants.