-
公开(公告)号:US20160136230A1
公开(公告)日:2016-05-19
申请号:US14898832
申请日:2014-07-01
Inventor: Sebastien Andre CAMPOS , John David HARLING
CPC classification number: A61K38/06 , A61K45/06 , C07K5/06017 , C07K5/06043 , C07K5/06078 , C07K5/0812
Abstract: A compound of formula (I): or a pharmaceutically acceptable salt thereof, compositions, combinations and medicaments containing said compounds and processes for their preparation. The invention also relates to the use of said compounds, combinations, compositions and medicaments, for example as inhibitors of the activity of the estrogen receptor, including degrading the estrogen receptor, the treatment of diseases and conditions mediated by the estrogen receptor.
Abstract translation: 式(I)化合物或其药学上可接受的盐,含有所述化合物的组合物,组合和药物及其制备方法。 本发明还涉及所述化合物,组合,组合物和药物的用途,例如作为雌激素受体活性的抑制剂,包括降解雌激素受体,治疗由雌激素受体介导的疾病和病症。
-
公开(公告)号:US20190040051A1
公开(公告)日:2019-02-07
申请号:US16073355
申请日:2017-02-10
Inventor: Niall Andrew ANDERSON , Nicholas Paul BARTON , Sebastien Andre CAMPOS , Edward Paul CANNONS , Anthony William James COOPER , Kenneth David DOWN , Kevin James DOYLE , Julie Nicole HAMBLIN , Graham George Adam INGLIS , Armelle LE GALL , Vipulkumar Kantibhai PATEL , Simon PEACE , Andrew SHARPE , Gemma Victoria WHITE
CPC classification number: C07D413/14 , A61P11/06 , A61P15/08 , A61P25/24 , A61P25/28 , A61P37/08 , C07D213/76
Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular PI3-kinase activity.
-
公开(公告)号:US20190161480A1
公开(公告)日:2019-05-30
申请号:US16323529
申请日:2017-08-07
IPC: C07D413/14 , A61P11/06
Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular PI3-kinase activity.
-
公开(公告)号:US20200071311A1
公开(公告)日:2020-03-05
申请号:US16572917
申请日:2019-09-17
Inventor: Niall Andrew ANDERSON , Nicholas Paul BARTON , Sebastien Andre CAMPOS , Edward Paul CANNONS , Anthony William James COOPER , Kenneth David DOWN , Kevin James DOYLE , Julie Nicole HAMBLIN , Graham George Adam INGLIS , Armelle LE GALL , Vipulkumar Kantibhai PATEL , Simon PEACE , Andrew SHARPE , Gemma Victoria WHITE
IPC: C07D413/14 , A61P15/08 , A61P25/24 , A61P37/08 , A61P11/06 , A61P25/28 , C07D213/76
Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular PI3-kinase activity.
-
5.
公开(公告)号:US20160368911A1
公开(公告)日:2016-12-22
申请号:US14898782
申请日:2014-07-01
Inventor: Sebastien Andre CAMPOS , John David HARLING , Afjal Hussain MIAH , Ian Edward, David SMITH
IPC: C07D417/14 , C07D413/14 , A61K31/422 , A61K45/06 , C07D471/10 , A61K31/435 , C07K5/062 , A61K38/05 , A61K31/427 , A61K31/496
CPC classification number: C07D417/14 , A61K31/422 , A61K31/427 , A61K31/435 , A61K31/496 , A61K38/05 , A61K45/06 , C07D409/12 , C07D409/14 , C07D413/14 , C07D471/10 , C07K5/06052
Abstract: A compound of formula (I): or a pharmaceutically acceptable salt thereof, compositions, combinations and medicaments containing said compounds and processes for their preparation. The invention also relates to the use of said compounds, combinations, compositions and medicaments, for example as inhibitors of the activity of the estrogen receptor, including degrading the estrogen receptor, the treatment of diseases and conditions mediated by the estrogen receptor,
Abstract translation: 或其药学上可接受的盐,含有所述化合物的组合物,组合和药物及其制备方法。 本发明还涉及所述化合物,组合,组合物和药物的用途,例如作为雌激素受体活性的抑制剂,包括降解雌激素受体,治疗由雌激素受体介导的疾病和病症,
-
-
-
-