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公开(公告)号:US20200071311A1
公开(公告)日:2020-03-05
申请号:US16572917
申请日:2019-09-17
发明人: Niall Andrew ANDERSON , Nicholas Paul BARTON , Sebastien Andre CAMPOS , Edward Paul CANNONS , Anthony William James COOPER , Kenneth David DOWN , Kevin James DOYLE , Julie Nicole HAMBLIN , Graham George Adam INGLIS , Armelle LE GALL , Vipulkumar Kantibhai PATEL , Simon PEACE , Andrew SHARPE , Gemma Victoria WHITE
IPC分类号: C07D413/14 , A61P15/08 , A61P25/24 , A61P37/08 , A61P11/06 , A61P25/28 , C07D213/76
摘要: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular PI3-kinase activity.
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公开(公告)号:US20190023715A1
公开(公告)日:2019-01-24
申请号:US16143788
申请日:2018-09-27
发明人: Zehong WAN , Xiaomin ZHANG , Jian WANG , Matthew Robert SENDER , Eric Steven MANAS , Raphael Anthony RIVERO , Joseph E PERO , Christopher Ernst NEIPP , Vipulkumar Kantibhai PATEL
IPC分类号: C07D487/14 , C07D513/14 , C07D498/14 , C07D487/04 , C07D471/14 , C07D491/20 , C07D471/20
CPC分类号: C07D487/14 , C07D471/14 , C07D471/20 , C07D487/04 , C07D491/20 , C07D498/14 , C07D513/14 , H05K999/99
摘要: The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example Alzheimer's disease.
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公开(公告)号:US20190040051A1
公开(公告)日:2019-02-07
申请号:US16073355
申请日:2017-02-10
发明人: Niall Andrew ANDERSON , Nicholas Paul BARTON , Sebastien Andre CAMPOS , Edward Paul CANNONS , Anthony William James COOPER , Kenneth David DOWN , Kevin James DOYLE , Julie Nicole HAMBLIN , Graham George Adam INGLIS , Armelle LE GALL , Vipulkumar Kantibhai PATEL , Simon PEACE , Andrew SHARPE , Gemma Victoria WHITE
CPC分类号: C07D413/14 , A61P11/06 , A61P15/08 , A61P25/24 , A61P25/28 , A61P37/08 , C07D213/76
摘要: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular PI3-kinase activity.
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公开(公告)号:US20190161480A1
公开(公告)日:2019-05-30
申请号:US16323529
申请日:2017-08-07
IPC分类号: C07D413/14 , A61P11/06
摘要: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular PI3-kinase activity.
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